Gastroesophageal Reflux Disease in the Neonatal Intensive Care Unit Neonate: Controversies, Current Understanding, and Future Directions.

Abstract:

:Gastroesophageal reflux (GER) is considered physiologic and is a normal process; whereas, when aerodigestive consequences are associated, it is often interpreted as GER disease (GERD). However, the distinction between them remains a challenge in infants in the NICU. Reflux-type of symptoms are heterogeneous, and often managed with changes in diet, feeding methods, and acid-suppressive therapy; all these empiric therapies lack objectivity; hence, practice variation is universal. We clarify the current controversies, explain the potential role of GERD in causing symptoms and complications, and highlight current advances. The evidence basis for the diagnostic strategies is discussed.

journal_name

Clin Perinatol

journal_title

Clinics in perinatology

authors

Hasenstab KA,Jadcherla SR

doi

10.1016/j.clp.2020.02.004

subject

Has Abstract

pub_date

2020-06-01 00:00:00

pages

243-263

issue

2

eissn

0095-5108

issn

1557-9840

pii

S0095-5108(20)30016-6

journal_volume

47

pub_type

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