Abstract:
AIMS:Urinary tract infection (UTI) is a common complication after pelvic floor surgery. Antibiotics as prophylaxis may reduce the prevalence of UTI's by 50%, but bacterial resistance may be a large disadvantage, necessitating the search for other possible prophylactic options. Recent research found a 50% reduction in the rate of UTI's with the use of cranberry capsules after elective gynecologic surgery, suggesting that cranberry capsules may serve as a good prophylaxis. The aim of this study was to assess whether perioperative cranberry prophylaxis reduces the risk of clinical overt UTI after elective pelvic floor surgery with indwelling catheter. METHODS:We conducted a single-center randomized, double-blind, placebo-controlled trial. Women were given cranberry capsules twice daily or identical placebo for 6 weeks, starting the day before surgery. The main endpoint of the trial was the incidence of UTI within 6 weeks after surgery, defined as clinical diagnosis and treatment of UTI by the medical doctor. Analyses were performed with the intention to treat. RESULTS:Two hundred ten participants were included, 105 in each arm. There was no significant difference in the prevalence of UTI between the cranberry arm (n = 13, 12.4%) and the placebo arm (n = 21, 20.0%; P = .13), but the prevalence in both arms was lower than anticipated. CONCLUSIONS:This trial shows no beneficial effect of adequately dosed cranberry prophylaxis in women undergoing pelvic floor surgery, although such effect cannot be ruled out in settings with a higher prevalence of UTI's.
journal_name
Neurourol Urodynjournal_title
Neurourology and urodynamicsauthors
Mooren ES,Liefers WJ,de Leeuw JWdoi
10.1002/nau.24391subject
Has Abstractpub_date
2020-06-01 00:00:00pages
1543-1549issue
5eissn
0733-2467issn
1520-6777journal_volume
39pub_type
杂志文章,随机对照试验abstract:AIM:Urinary incontinence is one of the most common, disruptive and often disabling conditions affecting frail older people living in community. The aims of present study were to describe the prevalence of bladder catheter in a population of older women living in community and to examine the relationship between urinary...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20059
更新日期:2004-01-01 00:00:00
abstract:AIMS:To evaluate if pelvic floor innervation differed in patients with rectocele compared to control subjects and to assess if nerve fiber density of the rectovaginal wall correlated to the clinical presentation of rectocele. METHODS:Biopsies from 24 female patients with posterior vaginal wall prolapse stage II (ICS-c...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20249
更新日期:2006-01-01 00:00:00
abstract:AIMS:Urodynamic studies (UDS) are complex, invasive and may be emotionally and physically distressing. Inadequate information may heighten distress. Prior to UDS, our patients receive written and verbal information, yet concerns remains that some women may not be adequately informed. This study examined how informed wo...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21014
更新日期:2011-04-01 00:00:00
abstract:AIMS:To systematically assess all available evidence on efficacy and safety of vanilloids for treating neurogenic lower urinary tract dysfunction (NLUTD) in patients with multiple sclerosis (MS). METHODS:This systematic review and meta-analysis was performed according to the Preferred Reporting Items for Systematic Re...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,meta分析,实务指引
doi:10.1002/nau.23314
更新日期:2018-01-01 00:00:00
abstract:AIMS:To identify clinical and urodynamic factors leading to spontaneous voiding in men with detrusor underactivity (DU) and suspected bladder outlet obstruction who underwent an outlet de-obstruction procedure. METHODS:We identified 614 men who underwent an outlet procedure at our institution from 2005 to 2014. Men we...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24122
更新日期:2019-11-01 00:00:00
abstract:AIMS:Pubovisceral (PV) muscle tears are associated with pelvic floor disorders. The goal of this study was to determine whether index finger palpatory assessment of PV muscle body integrity through the lateral vaginal wall is a reliable indicator of PV muscle tear severity diagnosed by magnetic resonance imaging (MRI)....
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23967
更新日期:2019-04-01 00:00:00
abstract:AIMS:We investigated the role of transient receptor potential ankyrin 1 (TRPA1) channel on the single unit mechanosensitive afferent activities (SAAs) primarily originating from the bladder in the rat. METHODS:Female Sprague-Dawley rats were used. Cystometry with continuous saline instillation was performed after intr...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22449
更新日期:2014-06-01 00:00:00
abstract:AIM:Here, we present the clinical presentation and surgical outcomes of women with symptomatic urethral prolapse presenting to our institution over 20 years, and seek to provide treatment recommendations for management of symptomatic urethral prolapse and caruncle. METHODS:A retrospective review of medical records fro...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23232
更新日期:2017-11-01 00:00:00
abstract:AIMS:The aim of our study was to access the variability of maximum flow rate (Q(max)), average flow rate (Q(av)) and flow pattern while varying the point of impact of flow on the flowmeter. METHODS:Water was delivered through a motorised tube holder in a standardised experimental set up. Flow was directed in 4 differe...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20846
更新日期:2010-09-01 00:00:00
abstract::Estrogens are known to have a major role in the function of the lower urinary tract although the role of exogenous estrogen replacement therapy in the management of women with lower urinary tract dysfunction remains controversial. Whilst for many years systemic and vaginal estrogen therapy was felt to be beneficial in...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.22464
更新日期:2014-09-01 00:00:00
abstract:AIMS:Nervous system involvement occurs in about half of patients with systemic lupus erythematosis (SLE). Seizures and psychiatric disorders are the most common manifestations; spinal cord lesions are uncommon. We had eight such patients who presented with urinary dysfunction. METHODS:The patients consisted of two men...
journal_title:Neurourology and urodynamics
pub_type: 临床试验,杂志文章
doi:10.1002/nau.10126
更新日期:2003-01-01 00:00:00
abstract:AIMS:Progressive weakness in pelvic floor tissues is extremely common and leads to the distressing problems of stress urinary incontinence (SUI) and pelvic organ prolapse (POP). There has been extensive work on a vast array of materials spanning synthetics, autografts, allografts, and xenografts. Uniaxial testing of ma...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.21156
更新日期:2012-01-01 00:00:00
abstract:AIM:NK-1 receptors in sensory nerves, the spinal cord and bladder smooth muscle participate in complex sensory mechanisms that regulate bladder activity. This study was designed to assess the efficacy and safety of a new NK-1 receptor antagonist, netupitant, in patients with OAB. METHODS:This was a phase II, multicent...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/nau.22406
更新日期:2014-03-01 00:00:00
abstract:AIMS:Lower urinary tract dysfunctions (LUTD) are very common in Multiple Sclerosis (MS), have a significant social impact, while the organic impact is discussed. We studied urinary complications and their risk factors in our cohort of MS patients, in order to improve the management of LUTD in MS. METHODS:Between 2004 ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22495
更新日期:2015-01-01 00:00:00
abstract:AIMS:Overactive bladder (OAB) affects over 17% of the population and significantly effect the health-related quality of life. The treatments for OAB include first line (lifestyle modification, pelvic floor muscle training), second line (anticholinergic or beta-3 agonist medications), and third line therapies (intradetr...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24158
更新日期:2019-11-01 00:00:00
abstract:AIMS:To assess the different treatment methods in management of neurogenic bladder (NGB) in patients with Parkinson's disease (PD). METHODS:A systematic search was performed in Cochrane library, EMBASE, Proquest, Clinicaltrial.gov, WHO, Google Scholar, MEDLINE via PubMed, Ovid, ongoing trials registers, and conference...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23869
更新日期:2019-01-01 00:00:00
abstract:AIMS:In the bladder, ATP is an important signaling molecule, which is released by bladder stretch and acid. We hypothesized that ATP might play a unique role in patients with OAB, characterized by low bladder volumes at first desire to void (FDV) and maximal cystometric capacity (MCC) and symptoms of frequency/urgency ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22344
更新日期:2013-09-01 00:00:00
abstract:AIMS:To determine the prevalence of urinary incontinence (UI) and associated factors in the institutionalized elderly. METHODS:A cross-sectional study is presented herein, conducted between October and December 2013, in 10 nursing homes in the city of Natal (Northeast Brazil). Individuals over the age of 60, who resid...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22675
更新日期:2016-01-01 00:00:00
abstract:AIMS:The objective of this document created by the ICCS standardization subcommittee is to provide a uniform guideline on measurement, quality control and documentation of urodynamic studies in children. METHODS:This guideline was created using expert opinion and critical review of the published literature on urodynam...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,实务指引,评审
doi:10.1002/nau.22783
更新日期:2015-09-01 00:00:00
abstract::In our hospital, we have followed a group of patients with familial amyloidotic polyneuropathy (FAP), type I. This disease is characterized by a progressive sensitive-motor and autonomic polyneuropathy. The amyloid fibrils of FAP I contain a mutant transthyretin (TTR) molecule. More than 90% of TTR production occurs i...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/(sici)1520-6777(1997)16:1<55::aid-nau7>3.0
更新日期:1997-01-01 00:00:00
abstract:AIMS:To evaluate the reproducibility of bladder sensation during standardized filling cystometry in female volunteers and overactive bladder (OAB) patients, repeated with weekly interval. METHODS:We recruited 13 female nulliparous volunteers (age 21-47) and 17 female patients with OAB between (age 18-72). They partici...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21100
更新日期:2011-11-01 00:00:00
abstract:AIM:To describe how the use of new and established animal models and methods can generate vital and far reaching experimental data in the study of mechanism underlying neurogenic bladder overactivity. METHODS:Bladder and colonic irradiated mice and those with upper and lower motor neuron lesions were used to study neu...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.21120
更新日期:2011-06-01 00:00:00
abstract:AIMS:To report for the first time bladder rupture during filling cystometry many years after bladder augmentation. METHODS:A 17-year-old girl with T10 meningomyelocele had received an ileocystoplasty, continent catheterizable stoma, and bladder neck sling for neurogenic bladder dysfunction and intractable incontinence...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20394
更新日期:2007-01-01 00:00:00
abstract:AIMS:To evaluate the impacts of hydrogen sulfide (H2 S) donor, sodium hydrogen sulfide (NaHS), and phosphodiesterase type-5 inhibitor (PDE5i), tadalafil per se and their combination treatment on partial bladder outlet obstruction (PBOO)-induced erectile dysfunction (ED). METHODS:Sprague-Dawley rats were equally divide...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24333
更新日期:2020-04-01 00:00:00
abstract:AIMS:Urgency is a key symptom in the diagnosis of overactive bladder (OAB), yet its definition and measurement are subject to continuing debate whether urinary urgency is a pathologic sensation or an intensification of normal desire to pass urine. The objective of this research was to explore the concept of urgency amo...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21242
更新日期:2012-04-01 00:00:00
abstract:AIMS:We sought to compare in-office physical exam findings via standing cough test (SCT) versus 24-hour pad weights among men seeking treatment for postprostatectomy stress urinary incontinence (SUI). METHODS:A retrospective review of a single surgeon database of incontinence procedures was performed. Documentation of...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24200
更新日期:2020-01-01 00:00:00
abstract:AIMS:To obtain improved assessment of bladder sensitivity during cystometry by using a 10 cm visual analogue scale (VAS), and comparing it with the standard method according to the International Continence Society (ICS). METHODS:Twenty-five patients with presumed normal bladder functioning underwent filling cystometri...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/nau.20301
更新日期:2007-01-01 00:00:00
abstract::This study was conducted to evaluate whether passive urethral resistance, detrusor internal work, and detrusor external work are independent measures of the voiding process. Passive urethral resistance, detrusor internal work, detrusor external work, and detrusor total work of 5 canines were determined under nonobstru...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/(SICI)1520-6777(1996)15:5<529::AID-NAU9>3.
更新日期:1996-01-01 00:00:00
abstract::For both treatment and research it is useful to classify detrusor hyperreflexia/instability according to degree of severity, because it relates to symptomatic impact. However, there has been no systematic evaluation of criteria for severity assignment. This report compares patient classification by urodynamic data acc...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.1930130507
更新日期:1994-01-01 00:00:00
abstract:AIMS:Phelan-McDermid syndrome (PMD) is a congenital syndrome caused by a deletion on chromosome 22q13.3. About 600 cases have been identified worldwide. PMD is characterized by neonatal hypotonia, moderate/severe intellectual impairment, impaired expressive language, and typical dysmorphic features. Psychological sympt...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24197
更新日期:2020-01-01 00:00:00