Abstract：
INTRODUCTION:Middle ear adenomatous neuroendocrine tumors are extremely rare neoplasms with epithelial and neuroendocrine differentiation, accounting for fewer than 2% of all middle and inner ear tumors. Universal standard surgical procedures for different stages of these tumors remain elusive due to the limitation of the small number of case reports or investigations. OBJECTIVE(S):This study intends to investigate proper surgical strategies for patients with middle ear adenomatous neuroendocrine tumors. METHODS:Six patients with middle ear adenomatous neuroendocrine tumors who were treated at the Second Affiliated Hospital of Nanchang University (Nanchang, China) and the Eye, Ear, Nose, and Throat Hospital of Fudan University (Shanghai, China) respectively. Clinical characteristics and management strategies of patients were reviewed. The mean follow-up time was 63.7 months (range, 13-153 months). All the information was collected from medical records and prognosis postoperatively. RESULTS:Three patients underwent canal wall-up tympanomastoidectomy, including one patient with recurrence who underwent a previous tympanotomy; the other three patients underwent lateral temporal bone resection All of these patients were followed up with no evidence of recurrence or metastasis. Patients underwent canal wall-up surgery treatment accompanied with hearing function preservation measurements during follow-up periods. CONCLUSIONS:Complete surgical resection provided good results for patients with middle ear adenomatous neuroendocrine tumors. The ossicular chain should be removed. Because of the propensity for local recurrence and invasiveness, as well as regional or distant metastasis of these tumors, it is necessary to schedule long-term follow-up and an observation plan postoperatively.
journal_name
Braz J Otorhinolaryngoljournal_title
Brazilian journal of otorhinolaryngologyauthors
Xie B,Zhang S,Dai C,Liu Ydoi
10.1016/j.bjorl.2020.05.011subject
Has Abstractpub_date
2020-06-15 00:00:00eissn
1808-8694issn
1808-8686pii
S1808-8694(20)30069-0pub_type
杂志文章abstract：UNLABELLED:Children with enlarged tonsils and adenoids usually present breathing abnormalities such as snoring, mouth breathing and sleep apnea. It is known that upper airway obstruction and consequent mouth breathing may result in pulmonary diseases. AIM:The goal of this preliminary study was to evaluate the inspirat...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s1808-8694(15)31263-5
更新日期：2005-09-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章,评审
doi：10.1590/s1808-86942011000100010
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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journal_title：Brazilian journal of otorhinolaryngology
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章,评审
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pub_type： 杂志文章
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：
更新日期：2009-05-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2017-01-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2011-06-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2005-05-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2008-05-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.5935/1808-8694.20130076
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pub_type： 杂志文章
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journal_title：Brazilian journal of otorhinolaryngology
pub_type：
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更新日期：2020-12-19 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2015-05-01 00:00:00
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pub_type： 杂志文章
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更新日期：2017-01-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2020-01-01 00:00:00
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更新日期：2020-08-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2015-09-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2019-01-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2011-09-01 00:00:00
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journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
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更新日期：2006-07-01 00:00:00
abstract：UNLABELLED:Sickle cell anemia is still a significant public health issue in underdeveloped and developing countries. Sickle cell disease is one of the most common inherited diseases in Brazil. It affects mainly the mixed race population. Approximately 1 African-Brazilian child is affected with sickle cell disease for e...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章,评审
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更新日期：2012-02-01 00:00:00
