Case report: Oral manifestations of systemic amyloidosis, an aid to diagnosis of multiple myeloma - report of two cases.


BACKGROUND:Amyloidosis is the term applied to a diverse group of disorders that share the features of deposition of amorphous, extracellular material at various sites. Amyloid deposits may occur locally or may involve various organs, resulting number of clinical manifestations. Amyloidosis of the head and neck is rare and reflects underlying plasma cell dyscrasia. METHODS:A 57-year-old female patient presented with multiple painful oral ulcerative lesions on tongue and bilateral buccal mucosa for 1year and 6 months duration and a 76-year old male patient with small yellowish nodules on mucosal surfaces of the tongue and buccal mucosa. Results both cases histopathologically diagnosed as amyloidosis. Further investigations confirmed multiple myeloma. CONCLUSION:unusual oral lesions could be the first sign of systemic diseases such as multiple myeloma that account the significance of the role of the oral and maxillofacial specialists and dental surgeons.


Dissanayaka DWVN,Bandara HMMR,Sabesan T,Mohomed YS,Siriwardena BSMS




Has Abstract


2020-12-19 00:00:00








  • Study of otoacoustic emissions during the female hormonal cycle.

    abstract:UNLABELLED:The hormonal changes that occur in a short time span promote modifications all over the woman's body, with physical and emotional manifestations which are frequently observed. AIM:to evaluate the activity of the external ciliated cells in women during their menstrual cycle, observing the effect of hormonal ...

    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Arruda PO,Silva IM

    更新日期:2008-01-01 00:00:00

  • Effect of mitomycin C on the secretion of granulocyte macrophages colonies stimulating factor and interleukin-5 in eosinophilic nasal polyps stromal culture.

    abstract:UNLABELLED:The research involving tissue factors, such as granulocyte macrophage colonies stimulating factor (GM-CSF) and interleukin 5 (IL-5), leads to the mechanisms involved in the maintenance of eosinophilia, which is essential for the pathogenesis on eosinophilic nasal polyps. Mitomycin C has been successfully use...

    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Crosara PF,Vasconcelos AC,Guimarães RE,Becker HM,Becker CG,Crosara SL,Nascimento E

    更新日期:2005-07-01 00:00:00

  • Prospective evaluation of the effect of early nasal layer closure on definitive repair in cleft palate patients.

    abstract:INTRODUCTION:The cleft palate is one of the most common congenital anomalies treated by plastic surgeons. The cleft width increases the tension of repair and necessitates excessive dissection that might affect maxillary growth. Decreasing the width of cleft minimize tension, dissection and may limit the impact on maxil...

    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Aljodah MA,Al-Zajrawee MZ

    更新日期:2020-05-05 00:00:00

  • Auditory steady state response in pediatric audiology.

    abstract:UNLABELLED:The main issue regarding pediatric audiology diagnosis is determining procedures to configure reliable results which can be used to predict frequency-specific hearing thresholds. AIM:To investigate the correlation between auditory steady-state response (ASSR) with other tests in children with sensorineural ...

    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Linares AE,Costa Filho OA,Martinez MA

    更新日期:2010-11-01 00:00:00

  • Molecular genetics of non-syndromic deafness.

    abstract::One in every 1,000 newborn suffers from congenital hearing impairment. More than 60% of the congenital cases are caused by genetic factors. In most cases, hearing loss is a multifactorial disorder caused by both genetic and environmental factors. Molecular genetics of deafness has experienced remarkable progress in th...

    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章,评审


    authors: Piatto VB,Nascimento EC,Alexandrino F,Oliveira CA,Lopes AC,Sartorato EL,Maniglia JV

    更新日期:2005-03-01 00:00:00

  • Evaluating the ototoxicity of an anti-MRSA peptide KR-12-a2.

    abstract:INTRODUCTION:Methicillin-resistant staphylococcus aureus is an emerging problem for the treatment of chronic suppurative otitis media, and also for pediatric tympanostomy tube otorrhea. To date, there are no effective topical antibiotic drugs to treat methicillin-resistant staphylococcus aureus otorrhea. OBJECTIVE:In ...

    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Sung CM,Kim HC,Cho YB,Shin SY,Jang CH

    更新日期:2018-01-01 00:00:00

  • Histomorphometric evaluation of calcium phosphate bone grafts on bone repair.

    abstract:UNLABELLED:Because of its biocompatibility and osteoconductive properties, calcium-phosphate cement has been used as bone surrogate. OBJECTIVE:The purpose of this study was to do a histomorphometric comparison of bone regeneration using hydroxyapatite biphasic ceramic, calcium-phosphate cement and autogenous bone graf...

    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Guimarães KB,Vasconcelos BC,Limeira Júnior Fde A,Sousa FB,Andrade ES,Vasconcellos RJ

    更新日期:2011-07-01 00:00:00

  • Balance improvement and reduction of likelihood of falls in older women after Cawthorne and Cooksey exercises.

    abstract:UNLABELLED:Vestibular system is the absolute referential for the maintenance of balance. Functional deficit with aging can result in balance disturbance and in increase of likelihood of falls. AIM:To verify whether specific therapeutic approach of the system can promote motor learning and can contribute to the improve...

    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Ribeiro Ados S,Pereira JS

    更新日期:2005-01-01 00:00:00

  • Different techniques for caudal extension graft placement in rhinoplasty: [[pt]]Diferentes técnicas para colocação de enxerto de extensão caudal em rinoplastia.

    abstract:INTRODUCTION:The caudal extension graft is usually a cartilage graft that overlaps the caudal margin of the nasal septum. A combination of the caudal extension graft and the tongue-in-groove technique is used to stabilize the nasal base, set tip projection, and refine the alar-columellar relationship. OBJECTIVES:In th...

    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Sazgar AA,Kheradmand A,Razfar A,Hajialipour S,Sazgar AK

    更新日期:2019-09-14 00:00:00

  • Auditory-perceptual analysis of voice in abused children and adolescents.

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    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Stivanin L,Santos FP,Oliveira CC,Santos Bd,Ribeiro ST,Scivoletto S

    更新日期:2015-01-01 00:00:00

  • Prevalence of depressive symptoms in patients with cleft lip and palate.

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    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Lima LS,Ribeiro GS,Aquino SN,Volpe FM,Martelli DR,Swerts MS,Paranaíba LM,Martelli Júnior H

    更新日期:2015-03-01 00:00:00

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    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Wang G,Li G,Wu J,Song P

    更新日期:2020-08-06 00:00:00

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    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: de Aquino TJM,de Oliveira JAA,Rossato M

    更新日期:2008-11-01 00:00:00

  • Surgical treatment strategy in Warthin tumor of the parotid gland.

    abstract:INTRODUCTION:Warthin tumors are the second most common benign tumors of the parotid gland. We examined the clinical features of Warthin tumors in our hospital, and analyzed the consistency within the literatures. OBJECTIVE:The aim of this study is to analyze the clinical features of Warthin tumors in our 10-year exper...

    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Lee DH,Yoon TM,Lee JK,Lim SC

    更新日期:2019-01-01 00:00:00

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    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Caly Dde N,Rapoport A,Curioni OA,Dedivitis RA,Cernea CR,Brandão LG

    更新日期:2013-09-01 00:00:00

  • Free Field Word recognition test in the presence of noise in normal hearing adults.

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    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Almeida GVM,Ribas A,Calleros J

    更新日期:2017-01-01 00:00:00

  • Otologic and audiologic characteristics of type 2 diabetics in a tertiary health institution in Nigeria.

    abstract:INTRODUCTION:This cross-sectional comparative study was carried out at the Diabetes outpatient clinic of LAUTECH Teaching Hospital (LTH) Ogbomoso, Nigeria. OBJECTIVE:This study assessed patterns of otologic diseases and auditory acuity among type 2 diabetics and determinants of these findings among diabetics. METHODS...

    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Adebola SO,Olamoyegun MA,Sogebi OA,Iwuala SO,Babarinde JA,Oyelakin AO

    更新日期:2016-09-01 00:00:00

  • Endoscopic cartilage tympanoplasty: full thickness and partial thickness tragal graft.

    abstract:INTRODUCTION:Cartilage is the grafting material of choice for certain disorders of the middle ear. The indications for its routine use remain controversial due to the possible detrimental effect on post-operative hearing. OBJECTIVE:The present study was carried out to report a personal experience with "tragal cartilag...

    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Parelkar K,Thorawade V,Marfatia H,Shere D

    更新日期:2020-01-01 00:00:00

  • Nasal septal perforation closure with bacterial cellulose in rabbits.

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    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Martinez Neto EE,Dolci JE

    更新日期:2010-07-01 00:00:00

  • Frontonasal dysplasia: clinical evaluation on audiological and brainstem electrophysiological profiles.

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    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Antoneli MZ,Giacheti CM,Genaro KF,Zorzetto NL,Richieri-Costa A

    更新日期:2011-09-01 00:00:00

  • Interpretation and use of caloric testing.

    abstract:UNLABELLED:Caloric testing is an otoneurologic evaluation of the status of the vestibular-ocular reflex; it allows an evaluation of each labyrinth separately. The main aspects on the use and interpretation of caloric testing are reviewed. METHOD:A systematic review of papers published in the past one hundred years on ...

    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章,评审


    authors: Gonçalves DU,Felipe L,Lima TM

    更新日期:2008-05-01 00:00:00

  • Cervical vestibular evoked myogenic potentials and video head impulse test in Ménière disease.

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    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Grigol TAAES,Lopes KC,Ganança FF

    更新日期:2020-01-01 00:00:00

  • Our 12 year experience with Montgomery T-tube in the management of acute blunt laryngotracheal trauma patients.

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    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Kaintura M,Wadhera R,Hernot S

    更新日期:2020-07-27 00:00:00

  • Non syndromic cleft lip and palate: relationship between sex and clinical extension.

    abstract:UNLABELLED:Cleft lip and/or palate represent the most common congenital anomaly of the face. AIM:To describe the correlation between non-syndromic cleft lip and/or palate and gender, and its severity in the Brazilian population. METHODS:Cross-sectional study, between 2009 and 2011, in a sample of 366 patients. The da...

    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Martelli DR,Machado RA,Swerts MS,Rodrigues LA,Aquino SN,Martelli Júnior H

    更新日期:2012-10-01 00:00:00

  • Nasal mucosa study of leprosy contacts with positive serology for the phenolic glycolipid 1 antigen.

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    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Martins AC,Miranda A,Oliveira ML,Bührer-Sékula S,Martinez A

    更新日期:2010-09-01 00:00:00

  • Effect of hearing aids use on speech stimulus decoding through speech-evoked ABR.

    abstract:INTRODUCTION:The electrophysiological responses obtained with the complex auditory brainstem response (cABR) provide objective measures of subcortical processing of speech and other complex stimuli. The cABR has also been used to verify the plasticity in the auditory pathway in the subcortical regions. OBJECTIVE:To co...

    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Leite RA,Magliaro FCL,Raimundo JC,Gândara M,Garbi S,Bento RF,Matas CG

    更新日期:2016-12-08 00:00:00

  • Total rhinectomy for nasal carcinomas.

    abstract:INTRODUCTION:Total rhinectomy is an uncommon procedure for the treatment of nasal malignancies, usually reserved for locally advanced tumors. There are few case series studying total rhinectomy in the literature, reporting conflicting results about recurrence and metastasis. OBJECTIVE:Evaluate prognosis of total rhine...

    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Girardi FM,Hauth LA,Abentroth AL

    更新日期:2020-01-01 00:00:00

  • Acute effects of radioiodine therapy on the voice and larynx of Basedow-Graves patients.

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    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Isolan-Cury RW,Monte O,Cury AN,Andrada E Silva MA,Duprat A,Marone M,Almeida Rd,Iglesias A

    更新日期:2008-03-01 00:00:00

  • Incidence of bifid uvula and its relationship to submucous cleft palate and a family history of oral cleft in the Brazilian population.

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    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


    authors: Sales SAG,Santos ML,Machado RA,Dias VO,Nascimento JE,Swerts MSO,Júnior HM,Martelli DRB

    更新日期:2018-01-01 00:00:00

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    journal_title:Brazilian journal of otorhinolaryngology

    pub_type: 杂志文章


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    更新日期:2020-12-26 00:00:00