Abstract:
:Workers exposed to fuels and paints may present alterations in several parameters. Thus, we assessed potential biomarkers, with the aim of detecting early changes in gasoline station attendants and painters. Blood samples were collected for the analysis of inflammatory and DNA damage markers, besides biochemical, haematological and oxidative stress parameters. Biochemical and haematological parameters, which are assessed with routine exams, showed few changes. However, these findings could mask the workers' real health status. Besides, markers of oxidative damage were not modified. Levels of inflammatory parameters (cytokines and nitric oxide levels) and the DNA damage marker 8-hydroxydeoxyguanosine were significantly changed in the workers. Our results suggest that inflammatory and DNA damage parameters can be potential biomarkers for the biological monitoring of workers exposed to fuels and paints and may contribute to the development of occupational protection standards.
journal_name
Arch Environ Occup Healthjournal_title
Archives of environmental & occupational healthauthors
Brum EDS,da Silva LM,Teixeira TP,Moreira LDR,Kober H,Lavall MC,Silva JÉPD,Piana M,Lenz LS,da Cruz IBM,Duarte T,Duarte MMMF,Brandão Rdoi
10.1080/19338244.2020.1783502subject
Has Abstractpub_date
2020-07-02 00:00:00pages
1-11eissn
1933-8244issn
2154-4700pub_type
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journal_title:Archives of environmental & occupational health
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