Blood lead level and Helicobacter pylori infection in a healthy population: A cross-sectional study.

Abstract:

:The aim of this study was to investigate whether elevated blood lead level (BLL) is a risk factor for Helicobacter pylori infection. Upper gastrointestinal endoscopy was performed on 2,625 subjects who visited a university hospital for general health examination. H. pylori infection was detected using histologic examination with Giemsa staining, and BLLs were measured. The mean BLL was 2.83 ± 1.31 μg/dL. The prevalence of H. pylori infection was 27.8%. The BLL was significantly higher in the H. pylori infection-positive group compared to the non-infected group (2.96 ± 1.33 μg/dL vs. 2.78 ± 1.30 μg/dL, p < 0.001), which remained significant after adjusting for other confounders. H. pylori infection significantly increased as the BLL increased (OR: 1.143, 95% CI 1.068-1.223). We found a relationship between BLL elevation and H. pylori infection rate.

authors

Park WJ,Kim SH,Kang W,Ahn JS,Cho S,Lim DY,Kim S,Moon JD

doi

10.1080/19338244.2019.1654969

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

333-338

issue

6

eissn

1933-8244

issn

2154-4700

journal_volume

75

pub_type

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