In Kluyveromyces lactis a Pair of Paralogous Isozymes Catalyze the First Committed Step of Leucine Biosynthesis in Either the Mitochondria or the Cytosol.

abstract：:Due to the globally observed increase in antibiotic resistance of bacterial pathogens and the simultaneous decline in new antibiotic developments, the need for alternative inactivation approaches is growing. This is especially true for the treatment of infections with the problematic ESKAPE pathogens, which include En...

journal_title：Frontiers in microbiology

authors： Hoenes K,Bauer R,Meurle T,Spellerberg B,Hessling M

更新日期：2021-01-13 00:00:00

abstract：:Candida glabrata is an opportunistic fungal pathogen that currently ranks as the second most common cause of candidiasis. Although the mechanisms underlying virulence and drug resistance in C. glabrata are now starting to be elucidated, we still lack a good understanding of how this yeast adapts during the course of a...

journal_title：Frontiers in microbiology

authors： Carreté L,Ksiezopolska E,Gómez-Molero E,Angoulvant A,Bader O,Fairhead C,Gabaldón T

更新日期：2019-02-12 00:00:00

abstract：:Climate change is accelerating the spread of plants and their associated species to new ranges. The differences in range shift capacity of the various types of species may disrupt long-term co-evolved relationships especially those belowground, however, this may be less so for seed-borne endophytic microbes. We collec...

journal_title：Frontiers in microbiology

authors： Geisen S,Kostenko O,Cnossen MC,Ten Hooven FC,Vreš B,van der Putten WH

更新日期：2017-08-29 00:00:00

abstract：:A type of photoheterotrophic bacteria contain a transmembrane light-driven proton pump called proteorhodopsins (PRs). Due to the prevalence of these organisms in the upper water column of the World's Ocean, and their potential for light-driven ATP generation, they have been suggested to significantly influence energy ...

journal_title：Frontiers in microbiology

authors： Courties A,Riedel T,Rapaport A,Lebaron P,Suzuki MT

更新日期：2015-07-10 00:00:00

abstract：:Bacterial host tropism is a primary determinant of the range of host organisms they can infect. Salmonella serotypes are differentiated into host-restricted and host-adapted specialists, and host-unrestricted generalists. In order to elucidate the underlying molecular mechanisms of host specificity in Salmonella infec...

journal_title：Frontiers in microbiology

authors： Kolenda R,Burdukiewicz M,Schiebel J,Rödiger S,Sauer L,Szabo I,Orłowska A,Weinreich J,Nitschke J,Böhm A,Gerber U,Roggenbuck D,Schierack P

更新日期：2018-08-22 00:00:00

abstract：:Schistosomiasis japonica is a significant health problem that leads to morbidity and mortality of humans. It is characterized by hepatic granulomatous response and fibrosis caused by eggs deposition in the liver. β-actin, a traditional housekeeping gene, is widely used as an internal control to normalize gene and prot...

journal_title：Frontiers in microbiology

authors： Zhang B,Wu X,Liu J,Song L,Song Q,Wang L,Yuan D,Wu Z

更新日期：2019-01-31 00:00:00

abstract：:This review describes target-enrichment approaches followed by next generation sequencing and their recent application to the research and diagnostic field of modern and past infectious human diseases caused by viruses, bacteria, parasites and fungi. ...

journal_title：Frontiers in microbiology

authors： Gaudin M,Desnues C

更新日期：2018-11-27 00:00:00

abstract：:A major global concern is the emergence and spread of systemic life-threatening fungal infections in critically ill patients. The increase in invasive fungal infections, caused most commonly by Candida and Aspergillus species, occurs in patients with impaired defenses due to a number of reasons such as underlying dise...

journal_title：Frontiers in microbiology

authors： Ravikumar S,Win MS,Chai LY

更新日期：2015-11-26 00:00:00

abstract：:Root-colonizing bacteria can support plant growth and help fend off pathogens. It is clear that such bacteria benefit from plant-derived carbon, but it remains ambiguous why they invest in plant-beneficial traits. We suggest that selection via protist predation contributes to recruitment of plant-beneficial traits in ...

journal_title：Frontiers in microbiology

authors： Amacker N,Gao Z,Agaras BC,Latz E,Kowalchuk GA,Valverde CF,Jousset A,Weidner S

更新日期：2020-12-15 00:00:00

abstract：:Ramoplanin is a glycolipodepsipeptide antibiotic obtained from fermentation of Actinoplanes sp. ATCC 33076 that exhibits activity against clinically important multi-drug-resistant, Gram-positive pathogens including vancomycin-resistant Enterococcus (VRE), methicillin-resistant Staphylococcus aureus (MRSA), and vancomy...

journal_title：Frontiers in microbiology

authors： de la Cruz M,González I,Parish CA,Onishi R,Tormo JR,Martín J,Peláez F,Zink D,El Aouad N,Reyes F,Genilloud O,Vicente F

更新日期：2017-03-06 00:00:00

abstract：:Merkel cell polyomavirus (MCV) plays a causal role in ∼80% of Merkel cell carcinomas (MCC). MCV is clonally integrated into the MCC tumor genome, which results in persistent expression of large T (LT) and small T (sT) antigen oncoproteins encoded by the early locus. In MCV-positive MCC tumors, LT is truncated by prema...

journal_title：Frontiers in microbiology

authors： Velásquez C,Amako Y,Harold A,Toptan T,Chang Y,Shuda M

更新日期：2018-04-11 00:00:00

abstract：:Bacteria adopt alternative cell fates during development. In Bacillus subtilis, the transition from planktonic growth to biofilm formation and sporulation is controlled by a complex regulatory circuit, in which the most important event is activation of Spo0A, a transcription factor and a master regulator for genes inv...

journal_title：Frontiers in microbiology

authors： Yan F,Yu Y,Wang L,Luo Y,Guo JH,Chai Y

更新日期：2016-06-28 00:00:00

abstract：:Objective: The aim of this study was to investigate the molecular mechanism of inflammasome activation in response to Streptococcus suis serotype 2 (SS2) infection and its contribution to the development of streptococcal toxic shock-like syndrome (STSS). Methods: To verify the role of suilysin (SLY) in STSS, we infect...

journal_title：Frontiers in microbiology

authors： Song L,Li X,Xiao Y,Huang Y,Jiang Y,Meng G,Ren Z

更新日期：2020-08-14 00:00:00

abstract：:Chagasic chronic cardiomyopathy is one of the most frequent and severe manifestations of Chagas disease, caused by the parasite Trypanosoma cruzi. The pathogenic and biochemical mechanisms responsible for cardiac lesions remain not completely understood, although it is clear that hypertrophy and subsequent heart dilat...

journal_title：Frontiers in microbiology

authors： Libisch MG,Faral-Tello P,Garg NJ,Radi R,Piacenza L,Robello C

更新日期：2018-08-16 00:00:00

abstract：:Interactions with microbes affect many aspects of animal biology, including immune system development, nutrition and health. In vertebrates, the gut microbiota is dominated by a small subset of phyla, but the species composition within these phyla is typically not conserved. Moreover, several recent studies have shown...

journal_title：Frontiers in microbiology

authors： Ellegaard KM,Engel P

更新日期：2016-09-21 00:00:00

abstract：:The microbiome within a poultry production house influences the attainment of physiologically strong birds and thus food safety and public health. Yet little is known about the microbial communities within the house and the effects on the soil microbes onto which the houses are placed; nor the effects of management pr...

journal_title：Frontiers in microbiology

authors： Crippen TL,Sheffield CL,Singh B,Byrd JA,Beier RC

更新日期：2019-09-13 00:00:00

abstract：:In this study, we characterized the β-lactamase genes and phenotypic resistance of cephalosporin-resistant Enterobacteriaceae isolated from retail foods in China. Of 1,024 Enterobacteriaceae isolates recovered from raw meat products, aquatic products, raw vegetables, retail-level ready-to-eat (RTE) foods, frozen foods...

journal_title：Frontiers in microbiology

authors： Ye Q,Wu Q,Zhang S,Zhang J,Yang G,Wang J,Xue L,Chen M

更新日期：2018-08-08 00:00:00

abstract：:We aimed at isolating lactic acid bacteria (LAB) from different plant materials to study their crossed-fermentation capacity in silos and to find strains able to confer enhanced aerobic stability to silage. A total of 129 LAB isolates were obtained from lucerne (alfalfa), maize, sorghum, ryegrass, rice, barley, canola...

journal_title：Frontiers in microbiology

authors： Puntillo M,Gaggiotti M,Oteiza JM,Binetti A,Massera A,Vinderola G

更新日期：2020-12-08 00:00:00

abstract：:The rapid detection of foodborne microbial pathogens contaminating fresh fruits and vegetables during the intervening period between harvest and consumption could revolutionize microbial quality assurance of food usually consumed raw and those with a limited shelf life. We have developed a sensitive, shotgun whole gen...

journal_title：Frontiers in microbiology

authors： Ogunremi D,Dupras AA,Naushad S,Gao R,Duceppe MO,Omidi K,Márquez IG,Huang H,Goodridge L,Lévesque RC,Hasan NA,Dadlani M,Dixon B,Magierowski S,Masson L

更新日期：2020-04-17 00:00:00

abstract：:Adequate comparisons of DNA and cDNA libraries from complex environments require methods for co-extraction of DNA and RNA due to the inherent heterogeneity of such samples, or risk bias caused by variations in lysis and extraction efficiencies. Still, there are few methods and kits allowing simultaneous extraction of ...

journal_title：Frontiers in microbiology

authors： Lim NY,Roco CA,Frostegård Å

更新日期：2016-10-18 00:00:00

abstract：:The cheese-derived strains Streptococcus thermophilus 84C isolated from Nostrano cheese, and Lactobacillus brevis DSM 32386 isolated from Traditional Mountain Malga cheese have been previously reported as γ-aminobutyric acid (GABA)-producers in vitro. In the present study, the ability of these strains to produce GABA ...

journal_title：Frontiers in microbiology

authors： Carafa I,Stocco G,Nardin T,Larcher R,Bittante G,Tuohy K,Franciosi E

更新日期：2019-02-13 00:00:00

abstract：:Cefquinome is a fourth generation cephalosporin with antimicrobial activity against gram negative and gram positive bacterial species, including Staphylococcus aureus. The aim of our study was to observe the ex-vivo activity of cefquinome against Staphylococcus aureus strains by using bovine serum from intravenously t...

journal_title：Frontiers in microbiology

authors： Ahmad I,Hao H,Huang L,Sanders P,Wang X,Chen D,Tao Y,Xie S,Xiuhua K,Li J,Dan W,Yuan Z

更新日期：2015-06-17 00:00:00

abstract：:During the pre-erythrocytic asymptomatic phase of malarial infection, sporozoites develop transiently inside less than 100 hepatocytes that subsequently release thousands of merozoites. Killing of these hepatocytes by cytotoxic T cells (CTLs) confers protection to subsequent malarial infection, suggesting that this bo...

journal_title：Frontiers in microbiology

authors： Bertolino P,Bowen DG

更新日期：2015-02-18 00:00:00

abstract：:Active volcanoes in Antarctica contrast with their predominantly cold surroundings, resulting in environmental conditions capable of selecting for versatile and extremely diverse microbial communities. This is especially true on Deception Island, where geothermal, marine, and polar environments combine to create an ex...

journal_title：Frontiers in microbiology

authors： Bendia AG,Signori CN,Franco DC,Duarte RTD,Bohannan BJM,Pellizari VH

更新日期：2018-05-07 00:00:00

abstract：:The gastrointestinal microbiome is crucial in human health. With greater than 10 times the cell count of an individual, the gastrointestinal microbiome provides many benefits to the host. It plays an important role in chronic illnesses and immune diseases and also following burns and trauma. This study aimed to determ...

journal_title：Frontiers in microbiology

authors： Huang G,Sun K,Yin S,Jiang B,Chen Y,Gong Y,Chen Y,Yang Z,Chen J,Yuan Z,Peng Y

更新日期：2017-07-06 00:00:00

abstract：:Most microbes can produce surface-associated or suspended aggregates called biofilms, which are encased within a biopolymer-rich matrix. The biofilm matrix provides structural integrity to the aggregates and shields the resident cells against environmental stressors, including antibiotic treatment. Microscopy permits ...

journal_title：Frontiers in microbiology

authors： Reichhardt C,Parsek MR

更新日期：2019-04-02 00:00:00

abstract：:Bacterial species differ greatly in the number and location of the rRNA operons which may be present in the bacterial chromosomes and plasmids. Most bacterial species contain more than one ribosomal RNA operon copy in their genomes, with some species containing up to 15 such copies. We review the number and location o...

journal_title：Frontiers in microbiology

authors： Espejo RT,Plaza N

更新日期：2018-06-08 00:00:00

abstract：:The dlt operon of Gram-positive bacteria is required for the incorporation of D-alanine esters into cell wall-associated teichoic acids (TAs). Addition of D-alanine to TAs reduces the negative charge of the cell envelope thereby preventing cationic antimicrobial peptides (CAMPs) from reaching their target of action on...

journal_title：Frontiers in microbiology

authors： Kamar R,Réjasse A,Jéhanno I,Attieh Z,Courtin P,Chapot-Chartier MP,Nielsen-Leroux C,Lereclus D,El Chamy L,Kallassy M,Sanchis-Borja V

更新日期：2017-08-03 00:00:00

abstract：:The estuarine nitrogen cycle can be substantially altered due to anthropogenic activities resulting in increased amounts of inorganic nitrogen (mainly nitrate). In the past, denitrification was considered to be the main ecosystem process removing reactive nitrogen from the estuarine ecosystem. However, recent reports ...

journal_title：Frontiers in microbiology

authors： Decleyre H,Heylen K,Van Colen C,Willems A

更新日期：2015-10-14 00:00:00

abstract：:Limited data are available on the contribution of wildlife to the spread of antibacterial resistance. We determined the prevalence of resistance to antibiotics in Escherichia coli isolates collected from wild animals in 2013 and 2014 and the genetic basis for resistance to third-generation cephalosporin in Guadeloupe....

journal_title：Frontiers in microbiology

authors： Guyomard-Rabenirina S,Reynaud Y,Pot M,Albina E,Couvin D,Ducat C,Gruel G,Ferdinand S,Legreneur P,Le Hello S,Malpote E,Sadikalay S,Talarmin A,Breurec S

更新日期：2020-07-10 00:00:00