Late presenters among minority patients with chronic hepatitis C infection in the USA.

Abstract:

OBJECTIVES:Minority patients are under-screened for chronic hepatitis C (CHC) in the USA, and limited data exist for minority patients with advanced fibrosis. METHODS:In this cross-sectional study, CHC patients who were prescribed direct-acting antiviral agents were divided into White patients and minority patient groups. Primary measurements were the mean fibrosis scores and percentages of patients with stage III-IV fibrosis (late presenters) for the two groups. RESULTS:Among the 1421 patients with self-reported ethnicity, 697 were White patients, and 724 were minority patients (484 Hispanic, 175 Black, 65 Asians). Compared to the White, minority patients had significantly higher mean fibrosis score (p < 0.001) and a higher percentage of late presenters (p < 0.001). In subgroup analyses, the mean fibrosis scores for Hispanic, Black and Asian patients were 2.58 ± 1.38, 2.28 ± 1.41 and 2.28 ± 1.40, respectively. CONCLUSIONS:Minority populations with CHC in the USA experience disparities in access to treatment in the early stages of liver fibrosis. Public health strategies are necessitated to address the inequality, as late presenters are at risk of hepatocellular carcinoma.

journal_name

Int J Public Health

authors

Pan CQ,Rabinovich C,Gayam V,Normatov M,Fidman B,Wang D

doi

10.1007/s00038-020-01467-3

subject

Has Abstract

pub_date

2020-09-01 00:00:00

pages

1181-1191

issue

7

eissn

1661-8556

issn

1661-8564

pii

10.1007/s00038-020-01467-3

journal_volume

65

pub_type

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