Abstract:
OBJECTIVES:The study aimed to assess the effect of demographic and clinical features of epilepsy, anxiety, depressed mood, sleep, and quality of life on the prediction of cognitive decline in patients with epilepsy. METHODS:Two hundred and six consecutive patients with epilepsy (age 41.8 ± 15.6 years, mean, SD) out of 279, were included in this cross-sectional study. We used simple linear regression to calculate the results. RESULTS:Objective cognitive status was predicted by anxiety and depression mood changes (Beck Anxiety Inventory (BAI), p = 0.03, Beck Depression Inventory (BDI), p = 0.005), language subdomain of Quality of Life Inventory in Epilepsy-89 (QOLIE-89) (p = 0.003), and total QOLIE-89 (p = 0.001). No significance was shown in demographic and clinical features of epilepsy (gender, age at onset, epilepsy duration, type, etiology of epilepsy, and antiepileptic treatment), except frequency of generalized epileptic seizures (p = 0.03), which also served as an independent predictor of anxiety (BAI) and depression (BDI). CONCLUSIONS:Our findings point at the role of mood changes in the cognitive status of patients with epilepsy, which should be used as an essential therapeutic target apart of seizure control.
journal_name
Int J Public Healthjournal_title
International journal of public healthauthors
Jarčušková D,Palušná M,Gazda J,Feketeová E,Gdovinová Zdoi
10.1007/s00038-020-01401-7subject
Has Abstractpub_date
2020-07-01 00:00:00pages
947-956issue
6eissn
1661-8556issn
1661-8564pii
10.1007/s00038-020-01401-7journal_volume
65pub_type
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更新日期:2008-01-01 00:00:00
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更新日期:2014-08-01 00:00:00
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更新日期:2015-05-01 00:00:00
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更新日期:2015-01-01 00:00:00
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更新日期:2017-11-01 00:00:00
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更新日期:2011-04-01 00:00:00
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更新日期:2017-12-01 00:00:00
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更新日期:2007-01-01 00:00:00
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更新日期:2011-06-01 00:00:00
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更新日期:2019-01-01 00:00:00
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更新日期:2012-04-01 00:00:00
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更新日期:2011-02-01 00:00:00