Recruitment of mesenchymal stem cells by stromal cell-derived factor 1α in pulp cells from deciduous teeth.

abstract：:To estimate the genetic and dietary factors influencing bone mineral density (BMD) in young adults, a total of 53 healthy volunteers (HV) (age 20.89+/-1.34), from whom informed consent was obtained, answered a questionnaire on dietary factors and had DNA from peripheral blood mononuclear cells analyzed for single nucl...

journal_title：International journal of molecular medicine

authors： Otsuki T,Sakaguchi H,Hatta E,Hatayama T,Hatada S,Miura Y,Takata-Tomokuni A,Hyodoh F,Tomomitsu T,Fukunaga M,Katsuyama H

更新日期：2004-10-01 00:00:00

abstract：:Hepatocellular carcinoma is a common type of cancer that is usually associated with poor prognosis. In this study, we examined the in vitro and in vivo mechanisms of the traditional Vietnamese herb Zanthoxylum avicennae on the inhibition of HA22T human hepatocellular carcinoma cell ...

journal_title：International journal of molecular medicine

authors： Dung TD,Chang HC,Binh TV,Lee MR,Tsai CH,Tsai FJ,Kuo WW,Chen LM,Huang CY

更新日期：2012-06-01 00:00:00

abstract：:Glioblastoma multiforme (GBM) is one of the most aggressive brain tumors. GBM represents >50% of primary tumors of the nervous system and ~20% of intracranial neoplasms. Standard treatment involves surgery, radiation and chemotherapy. However, the prognosis of GBM is usually poor, with a median survival of 15 months. ...

journal_title：International journal of molecular medicine

authors： Bryukhovetskiy I,Ponomarenko A,Lyakhova I,Zaitsev S,Zayats Y,Korneyko M,Eliseikina M,Mischenko P,Shevchenko V,Shanker Sharma H,Sharma A,Khotimchenko Y

更新日期：2018-08-01 00:00:00

abstract：:We evaluated the mechanism of antitumor effects of buserelin, which is one of LH-RH agonists, on a hormone dependent breast cancer model, using 7,12-dimethylbenz(a)anthracene (DMBA)-induced rat mammary cancer. Rats developing solid mammary tumors within 5-7 weeks following the DMBA administration were divided into gro...

journal_title：International journal of molecular medicine

authors： Koibuchi Y,Sugamata N,Iino Y,Yokoe T,Andoh T,Maemura M,Takei H,Horiguchi J,Matsumoto H,Morishita Y

更新日期：1999-08-01 00:00:00

abstract：:We describe a novel spontaneous autosomal recessive mutation, cervelet-4 (crv4), which arose in a BALB/c strain. Mice homozygous for the mutation exhibit principally a reduced body size, a congenital neurological phenotype characterized by ataxic gait and intention tremor, with no gross anomalies observed in brain or ...

journal_title：International journal of molecular medicine

authors： Conti V,Aghaie A,Cilli M,Martin N,Caridi G,Musante L,Candiano G,Castagna M,Fairen A,Ravazzolo R,Guenet JL,Puliti A

更新日期：2006-10-01 00:00:00

abstract：:Resveratrol is a representative polyphenol of diet‑derived putative cancer chemopreventive agents, which have attracted increasing interest in the cancer chemoprevention community. The inhibition of the action of human papillomavirus (HPV) E6 and E7 has been considered a key approach for cervical cancer therapy. Resve...

journal_title：International journal of molecular medicine

authors： Sun X,Fu P,Xie L,Chai S,Xu Q,Zeng L,Wang X,Jiang N,Sang M

更新日期：2021-01-01 00:00:00

abstract：:Fruits, vegetables, spices and a variety of teas are suggested for the prevention of many diseases. They encompass active, non-nutritional ingredients called nutraceuticals which are defined as food products that provide health benefits. Many nutraceuticals have been tested to identify inhibitors of plasminogen activa...

journal_title：International journal of molecular medicine

authors： Jankun J,Skotnicka M,Łysiak-Szydłowska W,Al-Senaidy A,Skrzypczak-Jankun E

更新日期：2011-04-01 00:00:00

abstract：:Endothelial progenitor cells (EPCs) are an independent factor predicting cardiovascular events. Visfatin plays an important role in the pathogenesis of various metabolic disorders. In this study, we examined the effects of visfatin on the apoptosis of EPCs and the mechanisms underlying these effects. Cultured EPCs pre...

journal_title：International journal of molecular medicine

authors： Sun L,Chen S,Gao H,Ren L,Song G

更新日期：2017-09-01 00:00:00

abstract：:The thermo-enhancement effects of the sesquiterpene lactone parthenolide (PTL), which targets the transcription factor nuclear factor-kappaB (NF-kappaB), and hyperthermia at 40, 42 and 44 degrees C on the human lung adenocarcinoma A549 cell line were investigated in vitro. Thermotherapy using a combined treatment with...

journal_title：International journal of molecular medicine

authors： Hayashi S,Hatashita M,Hayashi A,Matsumoto H,Shioura H,Kitai R

更新日期：2008-05-01 00:00:00

abstract：:Tumor suppressor gene mutations in TSG101, FHIT, and PTEN/MMAC1 were found in many types of cancer and the defects in these genes are responsible for the tumor development. Since aberrant transcripts of these genes were also identified in normal tissues, the significance of these mutations in carcinogenesis has become...

journal_title：International journal of molecular medicine

authors： Wang NM,Chang JG

更新日期：1999-05-01 00:00:00

abstract：:A wide range of therapeutic options exists for the treatment of keloids, all of which have their own strengths; however, a high risk of side‑effects and frequent recurrence remains. Therefore, the present study aimed to identify improved therapeutic approaches or drugs for the treatment of keloids. Ginsenoside Rg3 (Rg...

journal_title：International journal of molecular medicine

authors： Tang M,Bian W,Cheng L,Zhang L,Jin R,Wang W,Zhang Y

更新日期：2018-03-01 00:00:00

abstract：:High mobility group box-1 protein (HMGB1), primarily from the nucleus, is released into the extracellular milieu either passively from necrotic cells or actively through secretion by monocytes/macrophages. Extracellular HMGB1 acts as a potent inflammatory agent by promoting the release of cytokines such as tumor necro...

journal_title：International journal of molecular medicine

authors： Kawahara K,Hashiguchi T,Masuda K,Saniabadi AR,Kikuchi K,Tancharoen S,Ito T,Miura N,Morimoto Y,Biswas KK,Nawa Y,Meng X,Oyama Y,Takenouchi K,Shrestha B,Sameshima H,Shimizu T,Adachi T,Adachi M,Maruyama I

更新日期：2009-05-01 00:00:00

abstract：:Apoptosis plays a critical role in the pathogenesis of chronic myocardial ischemia (CMI) and heart failure (HF). Endoplasmic reticulum stress (ERS) is one of the newly defined signaling pathways which initiate apoptosis. Previous studies have shown that ERS-associated apoptosis is involved in the pathogenesis of HF in...

journal_title：International journal of molecular medicine

authors： Xin W,Li X,Lu X,Niu K,Cai J

更新日期：2011-04-01 00:00:00

abstract：:A role of GLP-1 (glucagon-like peptide-1) in the recovery of the metabolic conditions of morbidly obese patients after bariatric surgery has been proposed. Exendin 4 (Ex-4) and exendin 9 (Ex-9) both have GLP-1-like effects upon glucose metabolism in human myocytes. We investigated in normal human adipocytes the effect...

journal_title：International journal of molecular medicine

authors： Sancho V,Nuche B,Arnés L,Cancelas J,González N,Díaz-Miguel M,Martín-Duce A,Valverde I,Villanueva-Peñacarrillo ML

更新日期：2007-06-01 00:00:00

abstract：:The tumor suppressor genes p15INK4B and p16INK4A, located in the chromosomal region 9p21, are frequently inactivated by homo- or hemizygous deletions, point mutation or promotor methylation in various types of cancer. No commercial probe is yet available that allows the detection of such deletions by FISH. Long distan...

journal_title：International journal of molecular medicine

authors： Bleichert A,Fiedler W,Claussen U,Ernst G,Loncarevic IF,Heller A,Liehr T,Kunert C,von Eggeling F

更新日期：2001-06-01 00:00:00

abstract：:Blood supply plays a crucial role in solid tumour development and leukaemogenesis. It has been suggested that blocking of angiogenesis could be possible in cancer therapy. We have demonstrated the antiproliferative activity of Gleditsia sinensis fruit extract (GSE) on various human solid tumour cancer cell lines as we...

journal_title：International journal of molecular medicine

authors： Chow LM,Chui CH,Tang JC,Lau FY,Yau MY,Cheng GY,Wong RS,Lai PB,Leung TW,Teo IT,Cheung F,Guo D,Chan AS

更新日期：2003-08-01 00:00:00

abstract：:Dynamin-related peptide 1 (Drpl)-mediated mitochondrial fission is an important process associated with cardiac dysfunction under different pathological conditions. The aim of the present study was to investigate the expression of Drpl during inflammatory myocardial injury. Sprague‑Dawley rats were treated intraperito...

journal_title：International journal of molecular medicine

authors： Shen YL,Shi YZ,Chen GG,Wang LL,Zheng MZ,Jin HF,Chen YY

更新日期：2018-04-01 00:00:00

abstract：:Evodiamine is a botanical alkaloid compound extracted from Tetradium plants. Previous studies have reported that evodiamine (Evo) treatment can reduce food uptake and improve insulin resistance in animals . The skeletal muscle comprises about 40% of the body mass of adults and has a vital role in regulating whole body...

journal_title：International journal of molecular medicine

authors： Yao X,Yu T,Zhao C,Li Y,Peng Y,Xi F,Yang G

更新日期：2018-03-01 00:00:00

abstract：:We have previously reported comparative genomics analyses on FGF3, FGF4, FGF6, FGF7, FGF8, FGF10, FGF11, FGF17, FGF18, FGF19, FGF20, FGF22 and FGF23 genes. Here, we performed comparative genomics analyses on FGF1, FGF2, FGF5, FGF9, FGF12, FGF13, FGF14, FGF16 and FGF21 genes, and further characterized the FGF16 gene. C...

journal_title：International journal of molecular medicine

authors： Katoh Y,Katoh M

更新日期：2005-11-01 00:00:00

abstract：:Mammalian cardiomyocytes may permanently lose their ability to proliferate after birth. Therefore, studying the proliferation and growth arrest of cardiomyocytes during the postnatal period may enhance the current understanding regarding this molecular mechanism. The present study identified the differentially express...

journal_title：International journal of molecular medicine

authors： Wang R,Su C,Wang X,Fu Q,Gao X,Zhang C,Yang J,Yang X,Wei M

更新日期：2018-01-01 00:00:00

abstract：:ARHGAP1, ARHGAP2, ARHGAP3, ARHGAP4, ARHGAP5, ARHGAP6, ARHGAP7 (DLC1), ARHGAP8, ARHGAP9, ARHGAP10, ARHGAP12, ARHGAP13 (SRGAP1), ARHGAP14 (SRGAP2), ARHGAP15, ARHGAP17 (RICH1), ARHGAP18, ARHGAP19, ARHGAP20, ARHGAP21, ARHGAP22, ARHGAP23, ARHGAP24, ARHGAP25, ARHGAP26, STARD13 (DLC2), HA-1, GMIP, PARG1, RACGAP1, PIK3R1, PIK...

journal_title：International journal of molecular medicine

authors： Katoh Y,Katoh M

更新日期：2004-11-01 00:00:00

abstract：:Burn trauma is a clinical condition accompanied by muscle wasting that severely impedes rehabilitation in burn survivors. Mitochondrial uncoupling protein 3 (UCP3) is uniformly expressed in myoskeletal mitochondria and its expression has been found to increase in other clinical syndromes that, like burn trauma, are as...

journal_title：International journal of molecular medicine

authors： Zhang Q,Cao H,Astrakas LG,Mintzopoulos D,Mindrinos MN,Schulz J 3rd,Tompkins RG,Rahme LG,Tzika AA

更新日期：2006-12-01 00:00:00

abstract：:The tree shrew (Tupaia belangeri) diverges from the primate order (Primates) and is classified as a separate taxonomic group of mammals - Scandentia. It has been suggested that the tree shrew can be used as an animal model for studying human diseases; however, the genomic sequence of the tree shrew is largely unidenti...

journal_title：International journal of molecular medicine

authors： Zheng Y,Yun C,Wang Q,Smith WW,Leng J

更新日期：2015-02-01 00:00:00

abstract：:Non‑small cell lung carcinoma (NSCLC) is a life‑threatening malignancy. The level of the cell growth regulator mitogen‑activated protein kinase kinase kinase kinase 3 (MAP4K3) has been shown to be correlated with a high risk of NSCLC recurrence and poor recurrence‑free survival rate. The present study examined the eff...

journal_title：International journal of molecular medicine

authors： Zhou Y,Hong T,Tong L,Liu W,Yang X,Luo J,Wang F,Li J,Yan L

更新日期：2018-12-01 00:00:00

abstract：:Androgen-independent growth of prostate cancer is correlated with expression of bcl-2. The impact of bcl-2 expression on the growth of prostate cancer cells following androgen ablation, was examined in the androgen-sensitive prostatic carcinoma cell line, LNCaP. Vector control and bcl-2 expressing LNCaP cells were gro...

journal_title：International journal of molecular medicine

authors： Beham AW,Sarkiss M,Brisbay S,Tu SM,von Eschenbach AC,McDonnell TJ

更新日期：1998-06-01 00:00:00

abstract：:Trypsinogen/trypsin is one of the major serine proteases and is produced by pancreatic acinar cells. Tumor-associated trypsinogen (TAT) has been reported to be produced by several cancer cell lines. The biological roles and activation mechanisms of both TAT and pancreatic acinar trypsinogen (PAT) have not been elucida...

journal_title：International journal of molecular medicine

authors： Uchima Y,Sawada T,Nishihara T,Umekawa T,Ohira M,Ishikawa T,Nishino H,Hirakawa K

更新日期：2003-12-01 00:00:00

abstract：:Celastrol, a natural biologically active compound isolated from Tripterygium wilfordii Hook F root extracts, has been shown to possess antitumor properties and therefore, is an interesting candidate for the development of novel chemotherapeutic cancer agents. In this study, we have demonstrated that Celastrol is a pot...

journal_title：International journal of molecular medicine

authors： Huang L,Zhang Z,Zhang S,Ren J,Zhang R,Zeng H,Li Q,Wu G

更新日期：2011-03-01 00:00:00

abstract：:Wiskott-Aldrich syndrome (WAS) is an X-linked recessive disorder characterized by microthrombocytopenia, eczema, immunodeficiency, and susceptibility to lymphoid malignancy. Loss-of-function mutations in WAS gene have been identified to cause disorders with platelet defects including WAS and X-linked thrombocytopenia....

journal_title：International journal of molecular medicine

authors： Chatchatee P,Srichomthong C,Chewatavorn A,Shotelersuk V

更新日期：2003-12-01 00:00:00

abstract：:Type 2 cytokine‑associated immunity may be involved in the pathogenesis of allergic asthma. Although interleukin 27 (IL‑27) has been reported as an initiator and suppressor of T‑helper 1 (Th1) and T‑helper 2 (Th2) responses, respectively, its effects on the development of asthma remain unclear. In the present study, m...

journal_title：International journal of molecular medicine

authors： Lu D,Lu J,Ji X,Ji Y,Zhang Z,Peng H,Sun F,Zhang C

更新日期：2020-08-01 00:00:00

abstract：:Sprouty (SPRY) was first identified in a genetic screen in Drosophila to be an antagonist of fibroblast growth factor (FGF) and epidermal growth factor (EGF) signaling, seemingly by inhibiting the Ras/MAP kinase pathway. During large scale DNA sequencing of the human fetal brain cDNA library, we cloned a novel splice ...

journal_title：International journal of molecular medicine

authors： Wang L,Ji C,Wu H,Xu J,Wu Q,Dai J,Yin G,Ye X,Gu S,Xie Y,Mao Y

更新日期：2003-11-01 00:00:00