Strong coupling of single quantum dots with low-refractive-index/high-refractive-index materials at room temperature.

abstract：:One of the most plausible scenarios of the origin of life assumes the preceding prebiotic autotrophic metabolism in sulfide-rich hydrothermal vent environments. However, geochemical mechanisms to harness the reductive power provided by hydrothermal systems remain to be elucidated. Here, we show that, under a geoelectr...

journal_title：Science advances

authors： Kitadai N,Nakamura R,Yamamoto M,Takai K,Yoshida N,Oono Y

更新日期：2019-06-19 00:00:00

abstract：:Human sleep is highly regulated by temperature. Might climate change-through increases in nighttime heat-disrupt sleep in the future? We conduct the inaugural investigation of the relationship between climatic anomalies, reports of insufficient sleep, and projected climate change. Using data from 765,000 U.S. survey r...

journal_title：Science advances

authors： Obradovich N,Migliorini R,Mednick SC,Fowler JH

更新日期：2017-05-26 00:00:00

abstract：:Skyrmions are topologically protected nanoscale magnetic spin entities in helical magnets. They behave like particles and tend to form hexagonal close-packed lattices, like atoms, as their stable structure. Domain boundaries in skyrmion lattices are considered to be important as they affect the dynamic properties of m...

journal_title：Science advances

authors： Matsumoto T,So YG,Kohno Y,Sawada H,Ikuhara Y,Shibata N

更新日期：2016-02-12 00:00:00

abstract：:Terrestrial predators can modulate the energy used for prey capture to maximize efficiency, but diving animals face the conflicting metabolic demands of energy intake and the minimization of oxygen depletion during a breath hold. It is thought that diving predators optimize their foraging success when oxygen use and e...

journal_title：Science advances

authors： Hazen EL,Friedlaender AS,Goldbogen JA

更新日期：2015-10-02 00:00:00

abstract：:Neural organoids provide a powerful tool for investigating neural development, modeling neural diseases, screening drugs, and developing cell-based therapies. Somatic cells have previously been reprogrammed by transcription factors (TFs) into sensory ganglion (SG) neurons but not SG organoids. We identify a combinatio...

journal_title：Science advances

authors： Xiao D,Deng Q,Guo Y,Huang X,Zou M,Zhong J,Rao P,Xu Z,Liu Y,Hu Y,Shen Y,Jin K,Xiang M

更新日期：2020-05-29 00:00:00

abstract：:The tet methylcytosine dioxygenase 2 (TET2) enzyme catalyzes the conversion of the modified DNA base 5-methylcytosine to 5-hydroxymethylcytosine. TET2 is frequently mutated or dysregulated in multiple human cancers, and loss of TET2 is associated with changes in DNA methylation patterns. Here, using newly developed TE...

journal_title：Science advances

authors： Wang L,Ozark PA,Smith ER,Zhao Z,Marshall SA,Rendleman EJ,Piunti A,Ryan C,Whelan AL,Helmin KA,Morgan MA,Zou L,Singer BD,Shilatifard A

更新日期：2018-11-07 00:00:00

abstract：:Ornithine transcarbamylase (OTC) deficiency is an X-linked urea cycle disorder associated with high mortality. Although a promising treatment for late-onset OTC deficiency, adeno-associated virus (AAV) neonatal gene therapy would only provide short-term therapeutic effects as the non-integrated genome gets lost during...

journal_title：Science advances

authors： Wang L,Yang Y,Breton C,Bell P,Li M,Zhang J,Che Y,Saveliev A,He Z,White J,Latshaw C,Xu C,McMenamin D,Yu H,Morizono H,Batshaw ML,Wilson JM

更新日期：2020-02-12 00:00:00

abstract：:During the Last Glacial Maximum, expansive continental ice sheets lowered globally averaged sea level ~130 m, exposing a land bridge at the Bering Strait. During the subsequent deglaciation, sea level rose rapidly and ultimately flooded the Bering Strait, linking the Arctic and Pacific Oceans. Observational records of...

journal_title：Science advances

authors： Pico T,Mitrovica JX,Mix AC

更新日期：2020-02-26 00:00:00

abstract：:Quantum walks, in virtue of the coherent superposition and quantum interference, have exponential superiority over their classical counterpart in applications of quantum searching and quantum simulation. The quantum-enhanced power is highly related to the state space of quantum walks, which can be expanded by enlargin...

journal_title：Science advances

authors： Tang H,Lin XF,Feng Z,Chen JY,Gao J,Sun K,Wang CY,Lai PC,Xu XY,Wang Y,Qiao LF,Yang AL,Jin XM

更新日期：2018-05-11 00:00:00

abstract：:Although electromagnetic brain stimulation is a promising treatment in neurology and psychiatry, clinical outcomes are variable, and underlying mechanisms are ill-defined, which impedes the development of new effective stimulation protocols. Here, we show, in vivo and ex vivo, that repetitive transcranial magnetic sti...

journal_title：Science advances

authors： Dufor T,Grehl S,Tang AD,Doulazmi M,Traoré M,Debray N,Dubacq C,Deng ZD,Mariani J,Lohof AM,Sherrard RM

更新日期：2019-10-30 00:00:00

abstract：:[This corrects the article DOI: 10.1126/sciadv.aaz7822.]. ...

journal_title：Science advances

authors：

更新日期：2020-07-08 00:00:00

abstract：:Human and murine skin wounding commonly results in fibrotic scarring, but the murine wounding model wound-induced hair neogenesis (WIHN) can frequently result in a regenerative repair response. Here, we show in single-cell RNA sequencing comparisons of semi-regenerative and fibrotic WIHN wounds, increased expression o...

journal_title：Science advances

authors： Gay D,Ghinatti G,Guerrero-Juarez CF,Ferrer RA,Ferri F,Lim CH,Murakami S,Gault N,Barroca V,Rombeau I,Mauffrey P,Irbah L,Treffeisen E,Franz S,Boissonnas A,Combadière C,Ito M,Plikus MV,Romeo PH

更新日期：2020-03-20 00:00:00

abstract：:By introducing a superconducting gap in Weyl or Dirac semimetals, the superconducting state inherits the nontrivial topology of their electronic structure. As a result, Weyl superconductors are expected to host exotic phenomena, such as nonzero-momentum pairing due to their chiral node structure, or zero-energy Majora...

journal_title：Science advances

authors： Bachmann MD,Nair N,Flicker F,Ilan R,Meng T,Ghimire NJ,Bauer ED,Ronning F,Analytis JG,Moll PJW

更新日期：2017-05-24 00:00:00

abstract：:Earthquakes in the continental crust commonly occur in the upper 15 to 20 km. Recent studies demonstrate that earthquakes also occur in the lower crust of collision zones and play a key role in metamorphic processes that modify its physical properties. However, details of the failure process and sequence of events tha...

journal_title：Science advances

authors： Petley-Ragan A,Ben-Zion Y,Austrheim H,Ildefonse B,Renard F,Jamtveit B

更新日期：2019-07-31 00:00:00

abstract：:Perovskite oxides with poor conductivity call for three-dimensional (3D) conductive scaffolds to demonstrate their superb reactivities for oxygen evolution reaction (OER). However, perovskite formation usually requires high-temperature annealing at 600° to 900°C in air, under which most of the used conductive framewor...

journal_title：Science advances

authors： Li BQ,Tang C,Wang HF,Zhu XL,Zhang Q

更新日期：2016-10-21 00:00:00

abstract：:Reef-building corals form their calcium carbonate skeletons within an extracellular calcifying medium (ECM). Despite the critical role of the ECM in coral calcification, ECM carbonate chemistry is poorly constrained in vivo, and full ECM carbonate chemistry has never been characterized based solely on direct in vivo m...

journal_title：Science advances

authors： Sevilgen DS,Venn AA,Hu MY,Tambutté E,de Beer D,Planas-Bielsa V,Tambutté S

更新日期：2019-01-16 00:00:00

abstract：:Goat domestication was critical for agriculture and civilization, but its underlying genetic changes and selection regimes remain unclear. Here, we analyze the genomes of worldwide domestic goats, wild caprid species, and historical remains, providing evidence of an ancient introgression event from a West Caucasian tu...

journal_title：Science advances

authors： Zheng Z,Wang X,Li M,Li Y,Yang Z,Wang X,Pan X,Gong M,Zhang Y,Guo Y,Wang Y,Liu J,Cai Y,Chen Q,Okpeku M,Colli L,Cai D,Wang K,Huang S,Sonstegard TS,Esmailizadeh A,Zhang W,Zhang T,Xu Y,Xu N,Yang Y,Han J,C

更新日期：2020-05-20 00:00:00

abstract：:Nitrogen oxides (NO x = NO + NO2) are a primary component of air pollution-a leading cause of premature death in humans and biodiversity declines worldwide. Although regulatory policies in California have successfully limited transportation sources of NO ...

journal_title：Science advances

authors： Almaraz M,Bai E,Wang C,Trousdell J,Conley S,Faloona I,Houlton BZ

更新日期：2018-01-31 00:00:00

abstract：:Multicellular organisms are composed of tissues that have distinct functions requiring specialized proteomes. To define the proteome of a live animal with tissue and subcellular resolution, we adapted a localized proteomics technology for use in the multicellular model organism Caenorhabditis elegans. This approach co...

journal_title：Science advances

authors： Reinke AW,Mak R,Troemel ER,Bennett EJ

更新日期：2017-05-10 00:00:00

abstract：:Cytosolic RNA sensing is a prerequisite for initiation of innate immune response against RNA viral pathogens. Signaling through RIG-I (retinoic acid-inducible gene I)-like receptors (RLRs) to TBK1 (Tank-binding kinase 1)/IKKε (IκB kinase ε) kinases is transduced by mitochondria-associated MAVS (mitochondrial antiviral...

journal_title：Science advances

authors： Xiang W,Zhang Q,Lin X,Wu S,Zhou Y,Meng F,Fan Y,Shen T,Xiao M,Xia Z,Zou J,Feng XH,Xu P

更新日期：2016-07-01 00:00:00

abstract：:There have been increasing attempts to reverse habitat degradation through active restoration, but few large-scale successes are reported to guide these efforts. Here, we report outcomes from a unique and very successful seagrass restoration project: Since 1999, over 70 million seeds of a marine angiosperm, eelgrass (...

journal_title：Science advances

authors： Orth RJ,Lefcheck JS,McGlathery KS,Aoki L,Luckenbach MW,Moore KA,Oreska MPJ,Snyder R,Wilcox DJ,Lusk B

更新日期：2020-10-07 00:00:00

abstract：:Here, we demonstrate the use of pump-probe microscopy for high-resolution studies of vermilion degradation. Vermilion (mostly α-HgS), an important red pigment used in historical paintings, blackens over time, and metallic Hg and β-HgS have been implicated as possible degradation products. Conventional analysis techniq...

journal_title：Science advances

authors： Yu J,Warren WS,Fischer MC

更新日期：2019-06-21 00:00:00

abstract：:A new set of time-of-day-dependent global maps of the lunar near-infrared water/hydroxyl (H2O/OH) absorption band strength near 2.8 to 3.0 μm constructed on the basis of Moon Mineralogy Mapper (M3) data is presented. The analyzed absorption band near 2.8 to 3.0 μm indicates the presence of surficial H2O/OH. To remove ...

journal_title：Science advances

authors： Wöhler C,Grumpe A,Berezhnoy AA,Shevchenko VV

更新日期：2017-09-08 00:00:00

abstract：:Biogenesis in prokaryotes and eukaryotes requires the insertion of α-helical proteins into cellular membranes for which they use universally conserved cellular machineries. In bacterial inner membranes, insertion is facilitated by YidC insertase and SecYEG translocon working individually or cooperatively. How insertas...

journal_title：Science advances

authors： Serdiuk T,Steudle A,Mari SA,Manioglu S,Kaback HR,Kuhn A,Müller DJ

更新日期：2019-01-30 00:00:00

abstract：:The exceptionally long quantum coherence times of phosphorus donor nuclear spin qubits in silicon, coupled with the proven scalability of silicon-based nano-electronics, make them attractive candidates for large-scale quantum computing. However, the high threshold of topological quantum error correction can only be ca...

journal_title：Science advances

authors： Hill CD,Peretz E,Hile SJ,House MG,Fuechsle M,Rogge S,Simmons MY,Hollenberg LC

更新日期：2015-10-30 00:00:00

abstract：:Colloidal-scale assemblies that reconfigure on demand may serve as the next generation of soft "microbots," artificial muscles, and other biomimetic devices. This requires the precise arrangement of particles into structures that are preprogrammed to reversibly change shape when actuated by external fields. The design...

journal_title：Science advances

authors： Han K,Shields CW 4th,Diwakar NM,Bharti B,López GP,Velev OD

更新日期：2017-08-04 00:00:00

abstract：:Eruptive phenomena at all scales, from hydrothermal geysers to flood basalts, can potentially be initiated or modulated by external mechanical perturbations. We present evidence for the triggering of magmatism on a global scale by the Chicxulub meteorite impact at the Cretaceous-Paleogene (K-Pg) boundary, recorded by ...

journal_title：Science advances

authors： Byrnes JS,Karlstrom L

更新日期：2018-02-07 00:00:00

abstract：:Adoptive cell transfers have emerged as a disruptive approach to treat disease in a manner that is more specific than using small-molecule drugs; however, unlike traditional drugs, cells are living entities that can alter their function in response to environmental cues. In the present study, we report an engineered p...

journal_title：Science advances

authors： Shields CW 4th,Evans MA,Wang LL,Baugh N,Iyer S,Wu D,Zhao Z,Pusuluri A,Ukidve A,Pan DC,Mitragotri S

更新日期：2020-04-29 00:00:00

abstract：:A sulfide-oxidizing microorganism, Desulfurivibrio alkaliphilus (DA), generates a consistent enrichment of sulfur-34 (34S) in the produced sulfate of +12.5 per mil or greater. This observation challenges the general consensus that the microbial oxidation of sulfide does not result in large 34S enrichments and suggests...

journal_title：Science advances

authors： Pellerin A,Antler G,Holm SA,Findlay AJ,Crockford PW,Turchyn AV,Jørgensen BB,Finster K

更新日期：2019-07-24 00:00:00

abstract：:Compound climate extremes are receiving increasing attention because of their disproportionate impacts on humans and ecosystems. However, risks assessments generally focus on univariate statistics. We analyze the co-occurrence of hot and dry summers and show that these are correlated, inducing a much higher frequency ...

journal_title：Science advances

authors： Zscheischler J,Seneviratne SI

更新日期：2017-06-28 00:00:00