Abstract:
:[This corrects the article DOI: 10.1126/sciadv.aaz7822.].
journal_name
Sci Advjournal_title
Science advancesauthors
doi
10.1126/sciadv.abd5216subject
Has Abstractpub_date
2020-07-08 00:00:00pages
eabd5216issue
28issn
2375-2548pii
abd5216journal_volume
6pub_type
已发布勘误相关文献
Science Advances文献大全abstract::Advanced molecular materials that combine two or more physical properties are typically constructed by combining different molecules, each being responsible for one of the properties required. Ideally, single molecules could take care of this combined functionality, provided they are self-assembled correctly and endow...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.1701017
更新日期:2017-09-29 00:00:00
abstract::The structure of many real-world systems is best captured by networks consisting of several interaction layers. Understanding how a multilayered structure of connections affects the synchronization properties of dynamical systems evolving on top of it is a highly relevant endeavor in mathematics and physics and has po...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.1601679
更新日期:2016-11-16 00:00:00
abstract::The geothermal heat flux is a critical thermal boundary condition that influences the melting, flow, and mass balance of ice sheets, but measurements of this parameter are difficult to make in ice-covered regions. We report the first direct measurement of geothermal heat flux into the base of the West Antarctic Ice Sh...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.1500093
更新日期:2015-07-10 00:00:00
abstract::Two-dimensional (2D) polymers hold great promise in the rational materials design tailored for next-generation applications. However, little is known about the grain boundaries in 2D polymers, not to mention their formation mechanisms and potential influences on the material's functionalities. Using aberration-correct...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.abb5976
更新日期:2020-08-14 00:00:00
abstract::Tropical forest fragmentation results in habitat and biodiversity loss and increased carbon emissions. Here, we link an increased likelihood of tropical forest loss to decreasing fragment size, particularly in primary forests. The relationship holds for protected areas, albeit with half the rate of loss compared with ...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aax8574
更新日期:2020-03-11 00:00:00
abstract::Hybrid organic-inorganic halide perovskites have shown remarkable optoelectronic properties, exhibiting an impressive tolerance to defects believed to originate from correlated motion of charge carriers and the polar lattice forming large polarons. Few experimental techniques are capable of directly probing these corr...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aaw5558
更新日期:2019-05-31 00:00:00
abstract::Behavioral and clinical studies suggest a critical role of substance P (SP)/neurokinin-1 receptor (NK-1R) signaling in alcohol dependence. Here, we examined regulation of GABA transmission in the medial subdivision of the central amygdala (CeM) by the SP/NK-1R system, and its neuroadaptation following chronic alcohol ...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aaz1050
更新日期:2020-03-18 00:00:00
abstract::Calcium silicate hydrate (C-S-H) is the binder in concrete, the most used synthetic material in the world. The main weakness of concrete is the lack of elasticity and poor flexural strength considerably limiting its potential, making reinforcing steel constructions necessary. Although the properties of C-S-H could be ...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.1701216
更新日期:2017-11-29 00:00:00
abstract::Among the existing elemental characterization techniques, particle-induced x-ray emission (PIXE) and energy-dispersive x-ray (EDX) spectroscopy are two of the most widely used in different scientific and technological fields. Here, we present the first quantitative laser-driven PIXE and laser-driven EDX experimental i...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.abc8660
更新日期:2021-01-15 00:00:00
abstract::During the Last Glacial Maximum, expansive continental ice sheets lowered globally averaged sea level ~130 m, exposing a land bridge at the Bering Strait. During the subsequent deglaciation, sea level rose rapidly and ultimately flooded the Bering Strait, linking the Arctic and Pacific Oceans. Observational records of...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aay2935
更新日期:2020-02-26 00:00:00
abstract::Cellular cross-talk between ubiquitination and other posttranslational modifications contributes to the regulation of numerous processes. One example is ADP-ribosylation of the carboxyl terminus of ubiquitin by the E3 DTX3L/ADP-ribosyltransferase PARP9 heterodimer, but the mechanism remains elusive. Here, we show that...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.abc0418
更新日期:2020-09-18 00:00:00
abstract::Bones adapt to mechanical forces according to strict principles predicting straight shape. Most bones are, however, paradoxically curved. To solve this paradox, we used computed tomography-based, four-dimensional imaging methods and computational analysis to monitor acute and chronic whole-bone shape adaptation and re...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aax8301
更新日期:2020-03-06 00:00:00
abstract::The cyclic GMP-AMP synthase (cGAS), a sensor of cytosolic DNA, is critical for the innate immune response. Here, we show that loss of cGAS in untransformed and cancer cells results in uncontrolled DNA replication, hyperproliferation, and genomic instability. While the majority of cGAS is cytoplasmic, a fraction of cGA...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.abb8941
更新日期:2020-10-14 00:00:00
abstract::Approaching predators cast expanding shadows (i.e., looming) that elicit innate defensive responses in most animals. Where looming is first detected and how critical parameters of predatory approaches are extracted are unclear. In mice, we identify a retinal interneuron (the VG3 amacrine cell) that responds robustly t...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.abc9920
更新日期:2020-11-18 00:00:00
abstract::Since Darwin's conception of sexual selection theory, scientists have struggled to identify the evolutionary forces underlying the pervasive differences between male and female behavior, morphology, and physiology. The Darwin-Bateman paradigm predicts that anisogamy imposes stronger sexual selection on males, which, i...
journal_title:Science advances
pub_type: 杂志文章,评审
doi:10.1126/sciadv.1500983
更新日期:2016-02-12 00:00:00
abstract::Nanometer-scale skyrmions are prospective candidates for information bits in low-power consumption devices owing to their topological nature and controllability with low current density. Studies on skyrmion dynamics in different classes of materials have exploited the topological Hall effect and current-driven fast mo...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aaz9744
更新日期:2020-06-17 00:00:00
abstract::Presently, the Indian Ocean (IO) resides in a climate state that prevents strong year-to-year climate variations. This may change under greenhouse warming, but the mechanisms remain uncertain, thus limiting our ability to predict future changes in climate extremes. Using climate model simulations, we uncover the emerg...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aay7684
更新日期:2020-05-06 00:00:00
abstract::The transcription factor p63 is a key mediator of epidermal development. Point mutations in p63 in patients lead to developmental defects, including orofacial clefting. To date, knowledge on how pivotal the role of p63 is in human craniofacial development is limited. Using an inducible transdifferentiation model, comb...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aaw0946
更新日期:2019-05-01 00:00:00
abstract::Fluid commonly flows in response to an external pressure gradient. However, when a tunnel-containing hydrogel is immersed in water, spontaneous flow occurs through the tunnel without any pressure gradient. We confirmed this flow in a wide range of plant- and animal-derived hydrogels. The flow appears to be driven by a...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aba0941
更新日期:2020-05-08 00:00:00
abstract::The hydrogen atom-the smallest and most abundant atom-is of utmost importance in physics and chemistry. Although many analysis methods have been applied to its study, direct observation of hydrogen atoms in a single molecule remains largely unexplored. We use atomic force microscopy (AFM) to resolve the outermost hydr...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.1603258
更新日期:2017-05-12 00:00:00
abstract::Species interactions have long been predicted to increase in intensity toward the tropics and low elevations because of gradients in climate, productivity, or biodiversity. Despite their importance for understanding global ecological and evolutionary processes, plant-animal interaction gradients are particularly diffi...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aau4403
更新日期:2019-02-20 00:00:00
abstract::Injection-induced earthquakes pose a serious seismic hazard but also offer an opportunity to gain insight into earthquake physics. Currently used models relating the maximum magnitude of injection-induced earthquakes to injection parameters do not incorporate rupture physics. We develop theoretical estimates, validate...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aap7528
更新日期:2017-12-20 00:00:00
abstract::The formation of the Isthmus of Panama stands as one of the greatest natural events of the Cenozoic, driving profound biotic transformations on land and in the oceans. Some recent studies suggest that the Isthmus formed many millions of years earlier than the widely recognized age of approximately 3 million years ago ...
journal_title:Science advances
pub_type: 杂志文章,评审
doi:10.1126/sciadv.1600883
更新日期:2016-08-17 00:00:00
abstract::Bacterial chemotaxis-a fundamental example of directional navigation in the living world-is key to many biological processes, including the spreading of bacterial infections. Many bacterial species were recently reported to exhibit several distinct swimming modes-the flagella may, for example, push the cell body or wr...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aaz6153
更新日期:2020-05-27 00:00:00
abstract::Planarians exhibit traits of cephalization but are unique among bilaterians in that they ingest food by means of goal-directed movements of a trunk-positioned pharynx, following protrusion of the pharynx out of the body, raising the question of how planarians control such a complex set of body movements for achieving ...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aaz0882
更新日期:2020-04-08 00:00:00
abstract::Mineralization is the most fundamental process in vertebrates. It is predominantly mediated by osteoblasts, which secrete mineral precursors, most likely through matrix vesicles (MVs). These vesicular structures are calcium and phosphate rich and contain organic material such as acidic proteins. However, it remains la...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aax0672
更新日期:2019-07-03 00:00:00
abstract::The control and use of light polarization in optical sciences and engineering are widespread. Despite remarkable developments in polarization-resolved imaging for life sciences, their transposition to strongly scattering media is currently not possible, because of the inherent depolarization effects arising from multi...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.1600743
更新日期:2017-09-01 00:00:00
abstract::The human transfer RNA methyltransferase 9-like gene (TRM9L, also known as KIAA1456) encodes a negative regulator of tumor growth that is frequently silenced in many forms of cancer. While TRM9L can inhibit tumor cell growth in vivo, the molecular mechanisms underlying the tumor inhibition activity of TRM9L are unknow...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aas9184
更新日期:2018-07-11 00:00:00
abstract::Self-propelling micromotors are emerging as a promising micro- and nanoscale tool for single-cell analysis. We have recently shown that the field gradients necessary to manipulate matter via dielectrophoresis can be induced at the surface of a polarizable active ("self-propelling") metallodielectric Janus particle (JP...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aay4412
更新日期:2020-01-29 00:00:00
abstract::Nanoparticles have been extensively used for inflammation imaging and photodynamic therapy of cancer. However, the major translational barriers to most nanoparticle-based imaging and therapy applications are the limited depth of tissue penetration, inevitable requirement of external irradiation, and poor biocompatibil...
journal_title:Science advances
pub_type: 杂志文章
doi:10.1126/sciadv.aat2953
更新日期:2019-01-09 00:00:00