Pulmonary Manifestations of Systemic Vasculitis in Children.

Abstract:

:Vasculitides are defined according to the vessel size involved, and they tend to affect certain organ systems. Pulmonary involvement is rare in the common childhood vasculitides, such as Kawasaki disease, IgA vasculitis (Henoch Schonlein purpura). On the other hand, lung involvement is common in a rare pediatric vasculitis, granulomatosis with polyangiitis (GPA) (Wegener granulomatosis), where respiratory system findings are common. A criterion in the Ankara 2008 classification criteria for GPA is the presence of nodules, cavities, or fixed infiltrates. The adult data suggest that rituximab may be an alternative to cyclophosphamide in induction treatment.

journal_name

Pediatr Clin North Am

authors

Cuceoglu MK,Ozen S

doi

10.1016/j.pcl.2020.09.014

subject

Has Abstract

pub_date

2021-02-01 00:00:00

pages

167-176

issue

1

eissn

0031-3955

issn

1557-8240

pii

S0031-3955(20)30136-X

journal_volume

68

pub_type

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