Clinical and genetic evidence that juvenile arthritis is not a single disease.

abstract：:Autologous and allogeneic hematopoietic stem cell transplantation (HSCT) can be used in the management of patients with autoimmune disorders. Experience gained in adults has helped to better define the conditioning regimens required and appropriate selection of patients who are most likely to benefit from autologous H...

journal_title：Pediatric clinics of North America

authors： Milanetti F,Abinun M,Voltarelli JC,Burt RK

更新日期：2010-02-01 00:00:00

abstract：:The benefits and possible detriment of resistance training have been noted extensively in the literature. Although the benefits of resistance training are well known, many professionals fail to heed scientific advice or follow appropriate recommendations for resistance training in adolescents. When developing a resist...

journal_title：Pediatric clinics of North America

authors： Miller MG,Cheatham CC,Patel ND

更新日期：2010-06-01 00:00:00

abstract：:With the recent mandate for early intervention services, the pediatrician is more involved than ever in the identification and evaluation of children with developmental disabilities. Developmental surveillance at routine visits and listening to parental concerns are crucial in the early diagnosis of developmental dela...

journal_title：Pediatric clinics of North America

authors： Levy SE,Hyman SL

更新日期：1993-06-01 00:00:00

abstract：:The causes of macroscopic and microscopic hematuria overlap; both are often caused by urinary tract infections or urethral/bladder irritation. Coexistent hypertension and proteinuria should prompt investigation for glomerular disease. The most common glomerulonephritis in children is postinfectious glomerulonephritis....

journal_title：Pediatric clinics of North America

authors： Brown DD,Reidy KJ

更新日期：2019-02-01 00:00:00

abstract：:The increase in single-parent families, step-families, maternal employment, and young children in substitute care are among several important changes in the American family in recent decades. Although it is not clear that these changes necessarily lead to negative outcomes in children, it is apparent that a variety of...

journal_title：Pediatric clinics of North America

authors： Dubowitz H,Newberger CM,Melnicoe LH,Newberger EH

更新日期：1988-12-01 00:00:00

abstract：:The clinical challenge of determining the medical conditions that are associated with obvious symptoms of gastroesophageal reflux and what diagnostic tests are appropriate to define this relationship is substantial. To determine which infants may be suffering from pathologic conditions associated with subtle signs of ...

journal_title：Pediatric clinics of North America

authors： Hillemeier AC

更新日期：1996-02-01 00:00:00

abstract：:As new therapies for pediatric asthma are approved by the Food and Drug Administration, clinicians should be aware of their benefits and limitations. Accompanying these therapies are potential obstacles, including the delivery of inhaled therapies and age-specific issues regarding implementation and adherence. New ins...

journal_title：Pediatric clinics of North America

authors： Anderson WC 3rd,Gleason MC,Miyazawa N,Szefler SJ

更新日期：2017-12-01 00:00:00

abstract：:In summary, it is apparent that discussions on substance abuse should begin at the prenatal visit and extend through adolescence. Educational efforts and preventive strategies must be given highest priority. Signs and symptoms may be subtle, and pediatricians should have a high index of suspicion, particularly for hig...

journal_title：Pediatric clinics of North America

authors： Fuller PG Jr,Cavanaugh RM Jr

更新日期：1995-04-01 00:00:00

abstract：:In summary, wheezing is a common manifestation of viral respiratory tract disease in infancy. The precise pathogenetic mechanisms of virus-induced wheezing and its sequelae are not clear, although recent reports about participation of the cellular and humoral immune systems are promising. Although therapies like those...

journal_title：Pediatric clinics of North America

authors： Skoner D,Caliguiri L

更新日期：1988-10-01 00:00:00

abstract：:Endocrine disorders are common in infants in the neonatal ICU. They often are associated with prematurity, low birth weight or very low birth weight, and small size for gestational age. They also frequently occur in infants who are critically ill or stressed. This article describes the most common conditions and curre...

journal_title：Pediatric clinics of North America

authors： Hyman SJ,Novoa Y,Holzman I

更新日期：2011-10-01 00:00:00

abstract：:The author discusses the epidemiology of injuries from motor vehicles, the leading killer of children. Type and mechanism of trauma, restrain use, children's relative risk, and issues for advocacy are presented in this article on the occupants of motor vehicles. ...

journal_title：Pediatric clinics of North America

authors： Robertson LS

更新日期：1985-02-01 00:00:00

abstract：:The last decade has seen an increase of interest in autism spectrum disorders (ASD). With the prevalence now approaching 1%, children with ASD are usually first evaluated by clinicians working in primary care, such as pediatricians and family practitioners. Although classic autism is easy to recognize, differentiating...

journal_title：Pediatric clinics of North America

authors： Nazeer A,Ghaziuddin M

更新日期：2012-02-01 00:00:00

abstract：:The more common and more glaring pitfalls in developmental diagnosis encountered during infancy and early childhood have been outlined. Much of the ability to avoid these traps depends on a comfortable understanding of the four spheres of early child development and a sound familiarity with the principles of developme...

journal_title：Pediatric clinics of North America

authors： Blasco PA

更新日期：1991-12-01 00:00:00

abstract：:The many diseases and disorders that frequently have ophthalmologic implications in the pediatric age group are discussed. ...

journal_title：Pediatric clinics of North America

authors： Richard JM,Friendly DS

更新日期：1983-12-01 00:00:00

abstract：:Ensuring the safety of young athletes is a priority among health care providers. Controversy remains as to the best method of preparticipation screening. The American Academy of Pediatrics and the American Heart Association currently recommend screening with history and physical examination, without routine electrocar...

journal_title：Pediatric clinics of North America

authors： Galas JM

更新日期：2014-02-01 00:00:00

abstract：:Intestinal failure (IF) is the ultimate malabsorption state, with multiple causes, requiring long-term therapy with enteral or intravenous fluids and nutrient supplements. The primary goal during management of children with potentially reversible IF is to promote intestinal autonomy while supporting normal growth, nut...

journal_title：Pediatric clinics of North America

authors： Mziray-Andrew CH,Sentongo TA

更新日期：2009-10-01 00:00:00

abstract：:Acutely poisoned children remain a common problem facing pediatricians working in acute care medicine in the United States and worldwide. The management of such children continues to be challenging, and their care has evolved throughout the years. The concept of gastric decontamination in acute poisoning has significa...

journal_title：Pediatric clinics of North America

authors： Hanhan UA

更新日期：2008-06-01 00:00:00

abstract：:The stress response in humans commonly includes elevations in plasma concentrations of glucocorticoids, catecholamines, glucagon, growth hormone, aldosterone, and renin, resulting in alterations in the metabolism of glucose and other energy substrates, and in increased sodium and water retention. In severe illness, tr...

journal_title：Pediatric clinics of North America

authors： Weise K,Zaritsky A

更新日期：1987-02-01 00:00:00

abstract：:The authors provide the reader with the pharmacologic tools useful in managing chronic pain in children. The agents discussed include the analgesics, the psychotropics, and miscellaneous anticonvulsants, antihistamines, steroids, and skeletal muscle relaxants. ...

journal_title：Pediatric clinics of North America

authors： Lacouture PG,Gaudreault P,Lovejoy FH Jr

更新日期：1984-10-01 00:00:00

abstract：:This article describes important aspects of health-care quality, quality improvement (QI), patient safety (PS), and approaches to research on QI/PS efforts. Common terminology to facilitate an understanding of QI and PS research is reviewed. Models for understanding system and process performance are discussed. Introd...

journal_title：Pediatric clinics of North America

authors： Niedner MF

更新日期：2016-04-01 00:00:00

abstract：:Feeding problems in infants and young children are common. In healthy children who are developing and growing normally, feeding problems are usually not serious and can be managed conservatively by reassuring the family and providing them with anticipatory guidance and follow-up. A majority of serious childhood feedin...

journal_title：Pediatric clinics of North America

authors： Borowitz KC,Borowitz SM

更新日期：2018-02-01 00:00:00

abstract：:Prevention of enuresis has not been studied directly. Positive results from a randomized clinical trial evaluating early intervention for children at risk for enuresis would establish the value of prevention and help to promote its practice. Enuresis is not a disease process, and therefore a clinical trial may never b...

journal_title：Pediatric clinics of North America

authors： Friman PC

更新日期：1986-08-01 00:00:00

abstract：:A left-to-right shunt lesions exists when blood from the left atrium, left ventricle, or aorta transits to the right atrium or its tributaries, the right ventricle, or the pulmonary artery. This article discusses: the incidence, types, embryology, clinical presentations, physical examinations, electrocardiographic fea...

journal_title：Pediatric clinics of North America

authors： Driscoll DJ

更新日期：1999-04-01 00:00:00

abstract：:The author discusses his experience with the flexible bronchoscope, covering current instrumentation, techniques, and indications and contraindications, showing that, when used carefully by a well-trained physician, the flexible bronchoscope is a safe, relatively simple, and effective tool for exploration of the pedia...

journal_title：Pediatric clinics of North America

authors： Wood RE

更新日期：1984-08-01 00:00:00

abstract：:Selected topics of violence against children and adolescents that occur in countries outside of the United States are discussed. Focus is given to middle-income and low-income countries and emphasis is placed on the epidemiology of this pressing public health problem, particularly on conditions that are peculiar to ch...

journal_title：Pediatric clinics of North America

authors： Forjuoh SN,Zwi AB

更新日期：1998-04-01 00:00:00

abstract：:The management of vesicoureteral reflux (VUR) is varied and remains controversial, which is likely because children with VUR have different risks for urinary tract infection or renal injury. Consequently, the treatment of VUR needs to be individualized based on the patient's characteristics. In this article, the autho...

journal_title：Pediatric clinics of North America

authors： Fonseca FF,Tanno FY,Nguyen HT

更新日期：2012-08-01 00:00:00

abstract：:More than 6 per cent of poisonings involve alcohols and glycols, reflecting their availability in a wide range of household products, including aftershave, brake fluid, gas line antifreeze, model airplane fuel, mouthwash, rubbing alcohol, and windshield washing solution. Diagnosis involves recognition of an osmolal ga...

journal_title：Pediatric clinics of North America

authors： Litovitz T

更新日期：1986-04-01 00:00:00

abstract：:Beginning with a brief description of mature anatomic pathways and neurotransmitters in the "pain system," this article details their development in the human fetus, neonate, and child. Special emphasis is given to the basic mechanisms and physiologic effects of opioid analgesia. The clinical implications of these dat...

journal_title：Pediatric clinics of North America

authors： Anand KJ,Carr DB

更新日期：1989-08-01 00:00:00

abstract：:Recently, great progress has been made in the development of vaccines against Hib. Four polysaccharide-protein conjugate vaccines are actively being tested. Three of these (PRP-D, HbOC, and PRP-OMP) are currently licensed for use in children at 15-18 months of age. Clinical trials of these vaccines in infants are curr...

journal_title：Pediatric clinics of North America

authors： Shapiro ED

更新日期：1990-06-01 00:00:00

abstract：:Evaluation of the newborn with hyperbilirubinemia is an important and commonly encountered problem in all clinical pediatric-based practices. Cholestatic jaundice is always pathologic and warrants prompt assessment. The timely evaluation and directed treatment of any jaundiced newborn are essential to prevent serious ...

journal_title：Pediatric clinics of North America

authors： Hicks BA,Altman RP

更新日期：1993-12-01 00:00:00