Abstract：
:This article outlines the use of alternative agents to TCAs and SSRIs. Features of the more commonly used alternative antidepressant agents are outlined. In addition, antidepressant agents that are currently either under development or used in other countries are indicated for completeness because it seems likely that many of these will be introduced in the United States within the next few years. Many of these agents will be used by pediatricians and child psychiatrists for treatment of depression in children, and although much further research is needed, the future for alternative antidepressants and augmenting strategies is extremely promising.
journal_name
Pediatr Clin North Amjournal_title
Pediatric clinics of North Americaauthors
McConville BJ,Chaney RO,Browne KL,Friedman L,Cottingham E,Nelson Ddoi
10.1016/s0031-3955(05)70067-5subject
Has Abstractpub_date
1998-10-01 00:00:00pages
1157-71issue
5eissn
0031-3955issn
1557-8240pii
S0031-3955(05)70067-5journal_volume
45pub_type
杂志文章,评审abstract：:Deformities are abnormalities of shape or form caused by abnormal or imbalanced mechanical forces. In prenatal deformation, most infants are intrinsically normal and the deformation results from extrinsic constraining forces. Most prenatal deformities will resolve spontaneously or with the application of counteracting...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/s0031-3955(16)36142-9
更新日期：1986-12-01 00:00:00
abstract：:Available infant formulas contain a vast assortment of carbohydrate, protein, and fat sources in an effort to emulate the composition of human milk. Although infants receiving commercial formulas thrive, physicians should be cognizant of differences in formula composition and the research that has resulted in the diff...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(16)38838-1
更新日期：1994-10-01 00:00:00
abstract：:Breast lesions, including mastalgia; benign proliferative changes; and benign masses, including fibroadenomas, are common in adolescents and young adult women. Breast cancer is rare in women less than 20 years old and uncommon in women less than 30 years old. Discrete masses in women less than 30 years old that do not...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(05)70140-1
更新日期：1999-06-01 00:00:00
abstract：:ADHD is a highly prevalent condition with the core symptoms of functionally impairing limitations in sustained attention and impulsivity/overactivity. Other frequent symptoms include overemotionality or overreactivity, academic underachievement, low self-esteem, and interpersonal difficulties. The assessment for and d...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(05)70157-7
更新日期：1999-10-01 00:00:00
abstract：:The stress response in humans commonly includes elevations in plasma concentrations of glucocorticoids, catecholamines, glucagon, growth hormone, aldosterone, and renin, resulting in alterations in the metabolism of glucose and other energy substrates, and in increased sodium and water retention. In severe illness, tr...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(16)36185-5
更新日期：1987-02-01 00:00:00
abstract：:Ingestion of potentially poisonous agents is a common reason for children to present to an emergency department. The clinician must decide whether gastrointestinal decontamination is indicated for these patients. The controversy over the type of gastrointestinal decontamination is resolving and recent recommendations ...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(05)70181-4
更新日期：1999-12-01 00:00:00
abstract：:Worldwide, cervical cancer is the fourth most common cancer among women. Human papillomavirus (HPV) vaccination, if broadly implemented, has the potential to significantly reduce global rates of morbidity and mortality associated with cervical and other HPV-related cancers. More than 100 countries around the world hav...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2015.08.004
更新日期：2016-02-01 00:00:00
abstract：:Varicella zoster virus (VZV), herpes simplex virus (HSV) and cytomegalovirus (CMV) are all members of the Herpesviridae family.Humans are the only source of infection for these double stranded DNA viruses. Infants may acquire these infections in utero, peripartum, or postnatally, resulting in a variety of clinical syn...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2004.03.005
更新日期：2004-08-01 00:00:00
abstract：:This article describes the evolution of board certification for pediatricians and the current ongoing assessment process called Maintenance of Certification (MOC). To be called a board-certified pediatrician under the MOC framework requires a level of training, competence, and knowledge that can only be achieved by co...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/j.pcl.2009.05.010
更新日期：2009-08-01 00:00:00
abstract：:The experience of hypoglycemia is probably the most feared and hated consequence of life with type 1 diabetes among pediatric patients and their parents. Although transient detrimental effects are clearly disturbing and may have severe results, there is surprisingly little evidence of long-term CNS damage, even after ...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/j.pcl.2005.08.002
更新日期：2005-12-01 00:00:00
abstract：:The evaluation of syncopal children or adolescents relies heavily on a thorough, detailed history and physical examination. All syncope associated with exercise or exertion must be considered dangerous. The ECG is mandatory, but other laboratory tests are generally of limited value unless guided by pertinent positives...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(05)70113-9
更新日期：1999-04-01 00:00:00
abstract：:Methicillin-resistant Staphylococcus aureus (MRSA) is an emerging bacterial infection worldwide, and community-acquired MRSA (CA-MRSA) infection, which has increased dramatically in frequency in many areas, is of particular clinical and public health concern. CA-MRSA outbreaks and severe infections have been reported ...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2006.05.004
更新日期：2006-08-01 00:00:00
abstract：:Ultimately, after gathering and assessing all available evidence, pediatricians and health care policymakers must make informed decisions on whether exposure to a specific agent has the potential to cause cancer in children. In the case of DES, for which the results were clear, there was no question that the drug shou...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(05)70370-9
更新日期：2001-10-01 00:00:00
abstract：:This article outlines a few of the hematologic problems that are particular to developing countries, particularly those of the tropics. Because of globalization and the increasing movement of populations, hematologists in wealthier countries must be aware of the general patterns of hematologic change in the important ...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(02)00087-1
更新日期：2002-12-01 00:00:00
abstract：:Most children with cancer are immunocompromised during therapy and for a variable period after completion of therapy. They are at an increased risk of infections, including vaccine-preventable infections. There is a reduction in immunity to vaccine-preventable diseases after completion of standard-dose chemotherapy an...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2007.10.012
更新日期：2008-02-01 00:00:00
abstract：:In an otherwise healthy child with acute dehydration known to be due to diarrhea or vomiting, the amount of deficit can best be estimated by accurate weight. Total serum protein and hematocrit provide a rough estimate of reduction in circulating blood volume, but calculation from these data will usually underestimate ...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/s0031-3955(16)32538-x
更新日期：1971-02-01 00:00:00
abstract：:In children, laboratory evaluations can assist in the screening of patients for inflammatory disorders, confirm diagnoses, allow for monitoring of disease activity and response to therapy, and suggest prognoses and risk of morbidities associated with rheumatic diseases. This review provides an overview of the usefulne...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2012.03.008
更新日期：2012-04-01 00:00:00
abstract：:Refugee children and international adoptees have special medical considerations that must be addressed. Providers must be aware of the immigration history, where, and under what circumstances the child lived and migrated to the United States. Federal guidelines exist regarding which infections should be screened for, ...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2017.03.011
更新日期：2017-08-01 00:00:00
abstract：:More than half of US adolescents will experiment with marijuana. Of those who try marijuana more than once, approximately one third will subsequently use marijuana regularly, although most will have stopped by their late 20s. Although genetic predisposition plays the most important role in determining who will develop...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(01)00011-6
更新日期：2002-04-01 00:00:00
abstract：:The presence of certain medical or orthopedic conditions need not preclude adolescents from being physically active and participating in sports. The benefits of continued physical activity far outweigh any concerns for potential complications for most such conditions. This article reviews sport participation guideline...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/j.pcl.2010.03.005
更新日期：2010-06-01 00:00:00
abstract：:Diuretics are used in various conditions with fluid overload. Their efficacy in the management of congestive heart failure is well documented. In contrast, the indication of diuretics in chronic lung disease and central nervous system disorders of the newborn have not been clearly established. Substantial pharmacologi...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(16)36766-9
更新日期：1989-10-01 00:00:00
abstract：:This article outlines and summarizes the rationale and the working process that was undertaken by the National Spina Bifida Program to address the issues of transitioning throughout the life course for persons growing up with spina bifida. Their challenges include achieving independent living, vocational independence,...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/j.pcl.2010.07.010
更新日期：2010-08-01 00:00:00
abstract：:Table 4 briefly summarizes the relative advantages and disadvantages of skin tests versus in vitro tests for detecting allergen-specific IgE. The skin test remains unexcelled as a sensitive and cost efficient test for specific IgE. The high degree of skin test sensitivity is very important when a patient must be evalu...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(16)36544-0
更新日期：1988-10-01 00:00:00
abstract：:Based on the current knowledge of pulmonary mechanics and the results of clinical studies, we have reviewed principles that govern gas exchange during assisted ventilation in infants with RDS. Guidelines for changes in ventilator settings have been presented with respect to their specific effects on CO2 elimination an...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(16)34977-x
更新日期：1986-02-01 00:00:00
abstract：:Sepsis remains a major clinical problem in children, with a high mortality rate. Recent discoveries have identified the major cytokines involved in sepsis and several anticytokine strategies have been used in clinical trials. Antiendotoxin, anticytokine, and even steroid therapy have been studied in humans, with limit...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(05)70469-7
更新日期：1997-02-01 00:00:00
abstract：:Although progress had been made in reducing cardiovascular disease (CVD) mortality, the positive trend has reversed in recent years, and CVD remains the most common cause of mortality in US women and men. Youth represent the future of CVD prevention; emerging evidence suggests exposure to risk factors in children cont...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2020.06.006
更新日期：2020-10-01 00:00:00
abstract：:College-age young women frequently experience a variety of menstrual-related complaints, including dysmenorrheal, menorrhagia, irregular menses, and menstrual-related mood changes. These problems deserve careful evaluation; they may reflect normal ovulatory menstrual symptoms or be suggestive of significant pathology ...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2004.10.004
更新日期：2005-02-01 00:00:00
abstract：:Neonatal surgery has reached a high degree of sophistication. We are now entering a new era of widespread screening of the unborn by means of ultrasound, with planned intrauterine, intrapartum, and immediate postpartum interventions. Many pediatric surgical centers are now focusing their investigative efforts on eluci...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(05)70031-6
更新日期：1998-06-01 00:00:00
abstract：:Spina bifida occurs when the neural tube fails to close during early fetal development, resulting in a range of neural tube defects (NTDs). The cause of spina bifida is not fully understood, but scientists believe that NTDs are the result of genetic and environmental factors acting simultaneously. The Centers for Dise...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2010.07.019
更新日期：2010-08-01 00:00:00
abstract：:Youth-onset type 2 diabetes is a serious public health problem for Indigenous people throughout the world. This article reviews the epidemiology, disease burden, treatment, and challenges in achieving successful clinical management of this disorder in Indigenous youth. Screening criteria and the complications and como...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2009.09.013
更新日期：2009-12-01 00:00:00
