Conjunctivitis in children.

abstract：:The innate immune response system forms an important line of defense by deploying a limited number of receptors specific for conserved microbial components. This deployment generates a rapid inflammatory response, while activating the adaptive immune system. Improvements in our understanding of the innate immune syste...

journal_title：Pediatric clinics of North America

authors： Kaur BP,Secord E

更新日期：2019-10-01 00:00:00

abstract：:Emergency medicine requires diagnosing unfamiliar patients with undifferentiated acute presentations. This requires hypothesis generation and questioning, examination, and testing. Balancing patient load, care across the severity spectrum, and frequent interruptions create time pressures that predispose humans to fast...

journal_title：Pediatric clinics of North America

authors： Medford-Davis LN,Singh H,Mahajan P

更新日期：2018-12-01 00:00:00

abstract：:Based on the current knowledge of pulmonary mechanics and the results of clinical studies, we have reviewed principles that govern gas exchange during assisted ventilation in infants with RDS. Guidelines for changes in ventilator settings have been presented with respect to their specific effects on CO2 elimination an...

journal_title：Pediatric clinics of North America

authors： Carlo WA,Martin RJ

更新日期：1986-02-01 00:00:00

abstract：:This article provides an overview of the composition of human milk, its variation, and its clinical relevance. The composition of human milk is the biological norm for infant nutrition. Human milk also contains many hundreds to thousands of distinct bioactive molecules that protect against infection and inflammation a...

journal_title：Pediatric clinics of North America

authors： Ballard O,Morrow AL

更新日期：2013-02-01 00:00:00

abstract：:Highly specialized pediatric critical care centers have matured significantly over the past two decades; however, access to this care is limited to tertiary care facilities and constrained by geography. With the advances of transport medicine, great distances can be spanned to bring critical care to the patient and pr...

journal_title：Pediatric clinics of North America

authors： Pon S,Notterman DA

更新日期：1993-04-01 00:00:00

abstract：:In this article, I have attempted to summarize the concept of intestinal permeability to antigens such as ingested food proteins, bacterial breakdown products, endotoxins, and enzymes. The mature gut retains the capacity to absorb macromolecules by a pinocytotic mechanism which is more pronounced during the neonatal p...

journal_title：Pediatric clinics of North America

authors： Walker WA

更新日期：1975-11-01 00:00:00

abstract：:In this article we reviewed some of the important concepts and techniques of molecular biology applied to the study of lymphoid malignancies. Molecular biology is a tool for addressing certain basic research and clinical questions. It is also a key to the development of a new perspective in biology and medicine. For t...

journal_title：Pediatric clinics of North America

authors： Kirsch IR

更新日期：1988-08-01 00:00:00

abstract：:Pediatric hematologist/oncologists have a critical role in the diagnosis and management of patients who have complex vascular anomalies. They provide the clinical and medical skills needed to diagnose, treat, and manage these patients. Hematologist/oncologists also provide support for clinical trials and drug developm...

journal_title：Pediatric clinics of North America

authors： Adams DM,Wentzel MS

更新日期：2008-04-01 00:00:00

abstract：:This article presents the studies that show that asthma in children is strongly associated with sensitization to dust mite and other indoor allergens. In addition, the recent evidence that this association reflects a causal relationship between allergen exposure and asthma is reviewed. The relevance of quantitative me...

journal_title：Pediatric clinics of North America

authors： Duff AL,Platts-Mills TA

更新日期：1992-12-01 00:00:00

abstract：:Spinal deformity is a relatively common disorder, particularly in teenage girls. Early detection is possible by a simple, quick visual inspection that should be a standard part of the routine examination of all preteen and teenage patients. Follow-up observation will reveal those curvatures that are progressive and pe...

journal_title：Pediatric clinics of North America

authors： Bunnell WP

更新日期：1986-12-01 00:00:00

abstract：:Caustic ingestions, both accidental and intentional, continue to cause significant morbidity and mortality. This article recommends the best methods of managing caustic ingestion and the related problems of foreign bodies in the digestive tracts of small children, and also stresses the need for prevention as the best ...

journal_title：Pediatric clinics of North America

authors： Friedman EM

更新日期：1989-12-01 00:00:00

abstract：:The development of feeding skills is an extremely complex process influenced by multiple anatomic, neurophysiologic, environmental, social, and cultural factors. Most children negotiate the necessary developmental sequence without significant difficulties. An understanding of the development of normal feeding abilitie...

journal_title：Pediatric clinics of North America

authors： Stevenson RD,Allaire JH

更新日期：1991-12-01 00:00:00

abstract：:Respiratory system involvement in cystic fibrosis is the leading cause of morbidity and mortality. Defects in the cystic fibrosis transmembrane regulator (CFTR) gene throughout the sinopulmonary tract result in recurrent infections with a variety of organisms including Pseudomonas aeruginosa, methicillin-resistant Sta...

journal_title：Pediatric clinics of North America

authors： Goetz DM,Singh S

更新日期：2016-08-01 00:00:00

abstract：:CAD results from atherosclerosis, a chronic disease process that has its origin in childhood. Children and adolescents can be at higher risk for CAD by virtue of being from families with premature CAD or familial dyslipoproteinemias. The plasma lipid and lipoprotein levels result from a number of complex metabolic pro...

journal_title：Pediatric clinics of North America

authors： Kwiterovich PO Jr

更新日期：1990-12-01 00:00:00

abstract：:The American family is changing. Pediatricians are increasingly aware of treating children within a family systems context. Patients present with a variety of biopsychosocial problems, and pediatrics must continue to adjust to fit the changing needs of children and their families. Pediatricians must view themselves as...

journal_title：Pediatric clinics of North America

authors： Richman JM,Chapman MV,Bowen GL

更新日期：1995-02-01 00:00:00

abstract：:The stress response in humans commonly includes elevations in plasma concentrations of glucocorticoids, catecholamines, glucagon, growth hormone, aldosterone, and renin, resulting in alterations in the metabolism of glucose and other energy substrates, and in increased sodium and water retention. In severe illness, tr...

journal_title：Pediatric clinics of North America

authors： Weise K,Zaritsky A

更新日期：1987-02-01 00:00:00

abstract：:This article describes developments in pain assessment in critically ill neonates and infants during the last 5 to 6 years. Pain assessment instruments show a redundancy of items and a lack of profound psychometric background. Although most research focuses primarily on acute pain, in clinical practice there is also t...

journal_title：Pediatric clinics of North America

authors： van Dijk M,Tibboel D

更新日期：2012-10-01 00:00:00

abstract：:Radiologic studies are a vital component in the workup and diagnosis of disease. An appropriate radiographic study will accurately rule in or rule out disease with the least possible harm. Special considerations are necessary for the imaging of children. Current trends in pediatric imaging support the increased use of...

journal_title：Pediatric clinics of North America

authors： Baker N,Woolridge D

更新日期：2013-10-01 00:00:00

abstract：:Neonatal infections continue to cause morbidity and mortality in infants. Among approximately 400,000 infants followed nationally, the incidence rates of early-onset sepsis infection within 3 days of life are 0.98 cases per 1000 live births. Newborn infants are at increased risk for infections because they have relati...

journal_title：Pediatric clinics of North America

authors： Santos RP,Tristram D

更新日期：2015-04-01 00:00:00

abstract：:The etiology of hypertension in children and adolescents is varied; however, the prevalence of pediatric primary hypertension is increasing. Early identification and appropriate management of hypertension in children and adolescents is important to prevent the development of hypertensive end organ disease. The 2017 Am...

journal_title：Pediatric clinics of North America

authors： Guzman-Limon M,Samuels J

更新日期：2019-02-01 00:00:00

abstract：:The presence of certain medical or orthopedic conditions need not preclude adolescents from being physically active and participating in sports. The benefits of continued physical activity far outweigh any concerns for potential complications for most such conditions. This article reviews sport participation guideline...

journal_title：Pediatric clinics of North America

authors： Diokno E,Rowe D

更新日期：2010-06-01 00:00:00

abstract：:Disorders of excessive sleepiness are uncommon in children. When they occur, the presentation is often consistent with the developmental age of the child and does not meet either historical or laboratory criteria determined with adults in mind. Because of these differences, the true diagnosis can be missed or inadequa...

journal_title：Pediatric clinics of North America

authors： Givan DC

更新日期：2004-02-01 00:00:00

abstract：:Ample evidence shows that what was formerly called "juvenile rheumatoid arthritis" is not a single disease. At least six separate diseases were included as subgroups or subtypes of juvenile rheumatoid arthritis in other classifications. The clinical and laboratory features that differentiate these diseases are discuss...

journal_title：Pediatric clinics of North America

authors： Fink CW,Fernandez-Vina M,Stastny P

更新日期：1995-10-01 00:00:00

abstract：:Cancer in children is rare and accounts for about 1% of all malignancies. In the developed world, however, it is the commonest cause of disease-related deaths in childhood, carrying with it a great economic and emotional cost. Cancers are assumed to be multivariate, multifactorial diseases that occur when a complex an...

journal_title：Pediatric clinics of North America

authors： Buka I,Koranteng S,Osornio Vargas AR

更新日期：2007-02-01 00:00:00

abstract：:In the clinical arena of transplantation, tolerance remains, for the most part, a concept rather than a reality. Although modern immunosuppression regimens have effectively handled acute rejection, nearly all organs except the liver commonly suffer chronic immunologic damage that impairs organ function, threatening pa...

journal_title：Pediatric clinics of North America

authors： Seyfert-Margolis V,Feng S

更新日期：2010-04-01 00:00:00

abstract：:This article addresses the current and desired future state of interprofessional practice in pediatric hospital medicine. It focuses on identifying optimal team composition and work patterns, describing the value of parent involvement on both the patient's care team and on operational teams, describing the need for in...

journal_title：Pediatric clinics of North America

authors： Baird J,Ashland M,Rosenbluth G

更新日期：2019-08-01 00:00:00

abstract：:Asthmatic children living in low-income families in United States inner city communities continue to have disproportionately high rates of hospitalizations, emergency department visits, disability, and death. Current research implicates a combination of environmental, biologic, and disease mismanagement factors that u...

journal_title：Pediatric clinics of North America

authors： Federico MJ,Liu AH

更新日期：2003-06-01 00:00:00

abstract：:Human autoinflammatory diseases (except for the periodic fever, adenopathy, pharyngitis, aphthae syndrom) are a heterogeneous group of genetically determined diseases characterized by seemingly unprovoked inflammation, in the absence of autoimmune or infective causes. Tremendous advances in the understanding of these ...

journal_title：Pediatric clinics of North America

authors： Padeh S

更新日期：2005-04-01 00:00:00

abstract：:In this article, we review theory and evidence on stigma and minority stress as social/structural determinants of health among lesbian, gay, bisexual, and transgender (LGBT) youth. We discuss different forms of stigma at individual (eg, identity concealment), interpersonal (eg, victimization), and structural (eg, laws...

journal_title：Pediatric clinics of North America

authors： Hatzenbuehler ML,Pachankis JE

更新日期：2016-12-01 00:00:00

abstract：:Feeding disorders are common in infants and children. Multiple interacting behavioral, anatomic, and functional factors all can impact on the feeding process, making the evaluation and treatment of pediatric disorders complex and challenging. Knowledge of the normal process of feeding and swallowing, a careful history...

journal_title：Pediatric clinics of North America

authors： Rudolph CD,Link DT

更新日期：2002-02-01 00:00:00