Abstract:
:Neonatal infections continue to cause morbidity and mortality in infants. Among approximately 400,000 infants followed nationally, the incidence rates of early-onset sepsis infection within 3 days of life are 0.98 cases per 1000 live births. Newborn infants are at increased risk for infections because they have relative immunodeficiency. This article provides evidence-based practical approaches to the diagnosis, management, and prevention of neonatal infections.
journal_name
Pediatr Clin North Amjournal_title
Pediatric clinics of North Americaauthors
Santos RP,Tristram Ddoi
10.1016/j.pcl.2014.11.010subject
Has Abstractpub_date
2015-04-01 00:00:00pages
491-508issue
2eissn
0031-3955issn
1557-8240pii
S0031-3955(14)00255-7journal_volume
62pub_type
杂志文章,评审abstract::In the past decade, considerable advances have occurred in our understanding of the pathophysiology of this disorder, its metabolic sequelae, and its management, particularly with respect to continuous low-dose insulin infusion and the potential benefits of phosphate. This article reviews these advances as they pertai...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)34608-9
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abstract::Children who have a dental home are more likely to receive preventative care, require fewer dental treatments, and are less likely to have dental disease. Many children demonstrate behavior management concerns that may impede families from establishing a dental home for their children. Conceptually, behavior concerns ...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
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abstract::The ingestion of caustic chemical agents, usually accidentally by children, produces a wide range of injuries from minor mouth burns to necrosis of the esophagus and stomach. The type of agent, amount, concentration, and duration of exposure are the determining factors. The treatment for the average burn is fairly wel...
journal_title:Pediatric clinics of North America
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abstract::Renal arteriography remains the only study to identify and define correctly both location and extent of renal artery stenosis. Because other studies do not adequately identify all children who have renal artery disease, it is reasonable to perform renal arteriography in those children with severe hypertension who do n...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)38485-1
更新日期:1993-02-01 00:00:00
abstract::The family is the most central and enduring influence on children. Families, regardless of their composition, are themselves subject to a variety of social forces that influence how well they are able to meet children's needs. Pediatricians who understand the functions families serve and the factors that constrain the...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
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abstract::Food allergies have become a growing public health concern. At present the standard of care focuses on avoidance of trigger foods, education, and treatment of symptoms following accidental ingestions. This article provides a framework for primary care physicians and allergists for the diagnosis, management, and treatm...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2015.07.012
更新日期:2015-12-01 00:00:00
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journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
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journal_title:Pediatric clinics of North America
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.pcl.2009.03.003
更新日期:2009-06-01 00:00:00
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journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2011.02.005
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abstract::This article presents the studies that show that asthma in children is strongly associated with sensitization to dust mite and other indoor allergens. In addition, the recent evidence that this association reflects a causal relationship between allergen exposure and asthma is reviewed. The relevance of quantitative me...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章
doi:10.1016/s0031-3955(16)38445-0
更新日期:1992-12-01 00:00:00
abstract::Healthy children may present acute mountain sickness (AMS) within a few hours after arrival at high altitudes. In few cases, serious complications may occur, including high-altitude pulmonary edema and rarely high-altitude cerebral edema. Those with preexisting conditions especially involving hypoxia and pulmonary hyp...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2020.09.015
更新日期:2021-02-01 00:00:00
abstract::Important first steps have been taken towards establishing how some nutrients interact with genes and affect intestinal adaptation. These mechanisms may be typical of how other nutrients influence cell function and turnover and help to maintain intestinal integrity. The dietary effects of nucleotides on intestinal cel...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(05)70415-6
更新日期:1996-04-01 00:00:00
abstract::Pediatric patients presenting with painless scrotal masses can be perplexing because of the long differential diagnosis. A careful plan based on the physical examination and sonogram findings localizes the mass to the testis or an extratesticular location. Sonography distinguishes solid from cystic lesions. Subsequent...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(05)70555-1
更新日期:1997-10-01 00:00:00
abstract::The experience of hypoglycemia is probably the most feared and hated consequence of life with type 1 diabetes among pediatric patients and their parents. Although transient detrimental effects are clearly disturbing and may have severe results, there is surprisingly little evidence of long-term CNS damage, even after ...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章
doi:10.1016/j.pcl.2005.08.002
更新日期:2005-12-01 00:00:00
abstract::Improvements in diagnosis and treatment have increased survival for many children with malignant bone tumors. New molecular genetic discoveries are providing insights into the mechanisms of tumorigenesis and may provide novel therapeutic modalities based on interfering with aberrant transcriptional activation by hybri...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(05)70445-4
更新日期:1996-08-01 00:00:00
abstract::Acute cerebrovascular injury in term and preterm infants is a cause of significant morbidity. Treatment efforts in the past have focused on attempts to prevent such injury by interceding during labor in term infants and improving neonatal care in preterm infants. Epidemiologic studies suggest that these strategies hav...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)38368-7
更新日期:1992-08-01 00:00:00
abstract::As a result of their preadoptive histories and experiences, internationally adopted children, especially those with a history of institutionalization, can present with a complex profile of developmental and behavioral issues. Although many children demonstrate significant recovery and resilience after joining their ad...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2005.06.010
更新日期:2005-10-01 00:00:00
abstract::Term infants who have sustained brain damage from intrauterine asphyxia can often be classified into one of two distinct clinical and radiologic syndromes. The first consists of damage to the cerebral hemispheres. The second consists of damage predominantly involving the basal ganglia and thalamus. Results of studies ...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)38623-0
更新日期:1993-10-01 00:00:00
abstract::The rheumatic diseases of childhood are a relatively common and extraordinarily diverse group of illnesses; nevertheless, they are at least distantly related by similarities of immunodysregulation. These pathophysiologic relationships are reflected in affected children in similarities of historical, physical, and labo...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)38808-3
更新日期:1994-08-01 00:00:00
abstract::Infections occur in childhood and adolescent athletes just as they do in all children and adolescents. Because of the sports environment, and in some instances the sport itself, athletes can be prone to infections that will alter their athletic performance or present risks to other athletes. Recognition of the infecti...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(02)00016-0
更新日期:2002-08-01 00:00:00
abstract::Highly specialized pediatric critical care centers have matured significantly over the past two decades; however, access to this care is limited to tertiary care facilities and constrained by geography. With the advances of transport medicine, great distances can be spanned to bring critical care to the patient and pr...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)38508-x
更新日期:1993-04-01 00:00:00
abstract::A left-to-right shunt lesions exists when blood from the left atrium, left ventricle, or aorta transits to the right atrium or its tributaries, the right ventricle, or the pulmonary artery. This article discusses: the incidence, types, embryology, clinical presentations, physical examinations, electrocardiographic fea...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
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abstract::Hyperthyroidism in infants and children usually is caused by Graves' disease; however, several other diseases can also produce hyperthyroidism in these age groups. Because the pathophysiology and clinical course of these conditions differ, optimal treatment depends on precise diagnosis. ...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)37011-0
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abstract::This article describes the process of clinical assessment that may lead to differential treatment of psychiatric-related learning difficulties. The authors review differences in information processing among individuals with attention, affective, and primary thought disorders. ...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章
doi:10.1016/s0031-3955(16)34578-3
更新日期:1984-04-01 00:00:00
abstract::I have stressed the known medical and environmental factors associated with unexpected, sudden death in sports in children, and I have recommended restrictions or environmental alterations to prevent sudden death associated with an individual sport. Medical problems such as cardiomyopathies, posterior mitral valve lea...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章
doi:10.1016/s0031-3955(16)34285-7
更新日期:1982-12-01 00:00:00
abstract::Obstructive sleep apnea (OSA) is increasingly recognized in children. There is accumulating robust evidence to support early diagnosis and treatment of this condition. The purpose of this review is to provide an update on the epidemiology, clinical features, complications, and treatment of childhood OSA. The authors h...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2008.10.012
更新日期:2009-02-01 00:00:00
abstract::This article provides an overview of the composition of human milk, its variation, and its clinical relevance. The composition of human milk is the biological norm for infant nutrition. Human milk also contains many hundreds to thousands of distinct bioactive molecules that protect against infection and inflammation a...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2012.10.002
更新日期:2013-02-01 00:00:00
abstract::Interprofessional collaborative practice (IPCP) is a service delivery approach that seeks to improve health care outcomes and the patient experience while simultaneously decreasing health care costs. The current article reviews the core competencies and current trends associated with IPCP, including challenges faced b...
journal_title:Pediatric clinics of North America
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abstract::This article describes the evolution of board certification for pediatricians and the current ongoing assessment process called Maintenance of Certification (MOC). To be called a board-certified pediatrician under the MOC framework requires a level of training, competence, and knowledge that can only be achieved by co...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章
doi:10.1016/j.pcl.2009.05.010
更新日期:2009-08-01 00:00:00
abstract::This article defines short bowel syndrome and reviews the pathophysiology, medical management, and surgical manipulations proposed to improve intestinal absorption. Emphasis is also placed on possible future methods of management. ...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)34904-5
更新日期:1985-10-01 00:00:00