Obstructive sleep breathing disorders.

abstract：:Significant advances have been made in the understanding of allograft rejection. There is growing awareness that allograft acceptance, or tolerance, is also an active process rather than a passive absence of rejection. Mechanistic awareness of this process has spawned many preclinical strategies for the prevention of ...

journal_title：Pediatric clinics of North America

authors： Pearl JP,Preston E,Kirk AD

更新日期：2003-12-01 00:00:00

abstract：:Recently, great progress has been made in the development of vaccines against Hib. Four polysaccharide-protein conjugate vaccines are actively being tested. Three of these (PRP-D, HbOC, and PRP-OMP) are currently licensed for use in children at 15-18 months of age. Clinical trials of these vaccines in infants are curr...

journal_title：Pediatric clinics of North America

authors： Shapiro ED

更新日期：1990-06-01 00:00:00

abstract：:Advances in genetics, including mapping the human genome, improved therapy for genetic disorders, recognition of the role of genetic factors in common diseases of adulthood, and new screening tests for carrier detection and presymptomatic diagnosis create an increased demand for and awareness of clinical genetic servi...

journal_title：Pediatric clinics of North America

authors： Bernhardt BA,Pyeritz RE

更新日期：1992-02-01 00:00:00

abstract：:This article outlines the use of alternative agents to TCAs and SSRIs. Features of the more commonly used alternative antidepressant agents are outlined. In addition, antidepressant agents that are currently either under development or used in other countries are indicated for completeness because it seems likely that...

journal_title：Pediatric clinics of North America

authors： McConville BJ,Chaney RO,Browne KL,Friedman L,Cottingham E,Nelson D

更新日期：1998-10-01 00:00:00

abstract：:Advancements in the care of children with cancer have, in part, been achieved through improvements in supportive care. Situations that require prompt care can occur at the time of presentation as well as during treatment. This article discusses the approach to children with fever and neutropenia, a complication encoun...

journal_title：Pediatric clinics of North America

authors： Henry M,Sung L

更新日期：2015-02-01 00:00:00

abstract：:More than half of US adolescents will experiment with marijuana. Of those who try marijuana more than once, approximately one third will subsequently use marijuana regularly, although most will have stopped by their late 20s. Although genetic predisposition plays the most important role in determining who will develop...

journal_title：Pediatric clinics of North America

authors： Gruber AJ,Pope HG Jr

更新日期：2002-04-01 00:00:00

abstract：:Extracorporeal membrane oxygenation has now evolved into standard therapy for patients unresponsive to conventional ventilatory and pharmacological support. This article presents a clinical review of extracorporeal life support and its application to neonatal and pediatric patients as well as children requiring circul...

journal_title：Pediatric clinics of North America

authors： Klein MD,Whittlesey GC

更新日期：1994-04-01 00:00:00

abstract：:Herpes simplex encephalitis (HSE) is an uncommon disease, yet 25 to 30 per cent of cases involve children. The initial clinical findings are nonspecific (fever, altered mental status), but most cases evolve to demonstrate focal neurologic signs and symptoms. The CSF is abnormal in over 90 per cent of cases. The EEG, C...

journal_title：Pediatric clinics of North America

authors： Kohl S

更新日期：1988-06-01 00:00:00

abstract：:Hospitals that care for children are establishing medical emergency or rapid response teams as system solutions for preventing unexpected but foreseeable respiratory and cardiac arrest on inpatient units. Typically, an experienced team of doctors and nurses responds quickly to a direct request by any level of staff or...

journal_title：Pediatric clinics of North America

authors： Tibballs J,van der Jagt EW

更新日期：2008-08-01 00:00:00

abstract：:Vascular malformations are rare but important skin disorders in children, which often require multidisciplinary care. The goal of this article is to orient pediatricians to the various types of vascular malformations. We discuss the clinical characteristics, diagnostic criteria, and management of capillary, venous, ar...

journal_title：Pediatric clinics of North America

authors： Huang JT,Liang MG

更新日期：2010-10-01 00:00:00

abstract：:Retinoblastoma is the most common neoplasm of the eye in childhood, and represents 3% of all childhood malignancies. Retinoblastoma is a cancer of the very young; two-thirds are diagnosed before 2 years of age and 95% before 5 years. Retinoblastoma presents in 2 distinct clinical forms: (1) a bilateral or multifocal, ...

journal_title：Pediatric clinics of North America

authors： Rodriguez-Galindo C,Orbach DB,VanderVeen D

更新日期：2015-02-01 00:00:00

abstract：:Ultimately, after gathering and assessing all available evidence, pediatricians and health care policymakers must make informed decisions on whether exposure to a specific agent has the potential to cause cancer in children. In the case of DES, for which the results were clear, there was no question that the drug shou...

journal_title：Pediatric clinics of North America

authors： DeBaun MR,Gurney JG

更新日期：2001-10-01 00:00:00

abstract：:Vaccines are now available for the prevention of hepatitis A and hepatitis B. In this article, biologics are reviewed with special attention to their use in the pediatric patient. Special attention is paid to issues that developed in 1999. For hepatitis A vaccine, it is the change in US recommendations regarding incre...

journal_title：Pediatric clinics of North America

authors： Malay S,Tizer K,Lutwick LI

更新日期：2000-04-01 00:00:00

abstract：:Early recognition and treatment of pediatric shock, regardless of cause, decreases mortality and improves outcome. In addition to the conventional parameters (eg, heart rate, systolic blood pressure, urine output, and central venous pressure), biomarkers and noninvasive methods of measuring cardiac output are availabl...

journal_title：Pediatric clinics of North America

authors： Mtaweh H,Trakas EV,Su E,Carcillo JA,Aneja RK

更新日期：2013-06-01 00:00:00

abstract：:With the recent mandate for early intervention services, the pediatrician is more involved than ever in the identification and evaluation of children with developmental disabilities. Developmental surveillance at routine visits and listening to parental concerns are crucial in the early diagnosis of developmental dela...

journal_title：Pediatric clinics of North America

authors： Levy SE,Hyman SL

更新日期：1993-06-01 00:00:00

abstract：:Disorders of excessive sleepiness are uncommon in children. When they occur, the presentation is often consistent with the developmental age of the child and does not meet either historical or laboratory criteria determined with adults in mind. Because of these differences, the true diagnosis can be missed or inadequa...

journal_title：Pediatric clinics of North America

authors： Givan DC

更新日期：2004-02-01 00:00:00

abstract：:Evaluation and treatment of acute musculoskeletal injuries can be rewarding for primary care providers. They are common presenting complaints, and with appropriate management, many patients make a full recovery in a short period of time. This article reviews basic principles of evaluation of acutely injured children, ...

journal_title：Pediatric clinics of North America

authors： Apel PJ,Howard A

更新日期：2014-12-01 00:00:00

abstract：:The control of nosocomial infection in a pediatric intensive care unit is important not only because of the serious nature of the patient's condition, but also because of the greater staff-patient contact and inevitable crowding of patients, staff, and equipment. In order to control the spread of nosocomial infection,...

journal_title：Pediatric clinics of North America

authors： Holzman BH,Scott GB

更新日期：1981-08-01 00:00:00

abstract：:In this review, the authors describe the current information on nutrition modulation of immunity, enumerate the various immunologic tests that are potentially useful in nutritional assessment, examine the reliability of tests predicting disease and complications, and discuss how immunologic evaluation may help in the ...

journal_title：Pediatric clinics of North America

authors： Puri S,Chandra RK

更新日期：1985-04-01 00:00:00

abstract：:Disorders of sodium and water homeostasis are common occurrences in pediatric practice. They reflect distinct problems in the regulation of total body sodium balance and water distribution, respectively. Each of these groups of disorders has separate afferent and efferent mechanisms that are activated during disease s...

journal_title：Pediatric clinics of North America

authors： Trachtman H

更新日期：1995-12-01 00:00:00

abstract：:Pediatric hematologist/oncologists have a critical role in the diagnosis and management of patients who have complex vascular anomalies. They provide the clinical and medical skills needed to diagnose, treat, and manage these patients. Hematologist/oncologists also provide support for clinical trials and drug developm...

journal_title：Pediatric clinics of North America

authors： Adams DM,Wentzel MS

更新日期：2008-04-01 00:00:00

abstract：:An "apparent life-threatening event" (ALTE) refers to an episode that is of concern to the caregiver and is associated with a combination of apnea, color change, change in tone, choking, or gagging. Although the natural history of ALTE is most often benign, there is a risk for subsequent morbidity and mortality. The p...

journal_title：Pediatric clinics of North America

authors： Dewolfe CC

更新日期：2005-08-01 00:00:00

abstract：:Laryngotracheal stenosis should be suspected in children with recurrent, prolonged, or atypical croup; a history of endotracheal intubation; or a history of stridor, feeding difficulties, and failure to thrive. Tracheotomy-dependent patients with acquired laryngotracheal stenosis are candidates for surgical interventi...

journal_title：Pediatric clinics of North America

authors： Lesperance MM,Zalzal GH

更新日期：1996-12-01 00:00:00

abstract：:Asthmatic children living in low-income families in United States inner city communities continue to have disproportionately high rates of hospitalizations, emergency department visits, disability, and death. Current research implicates a combination of environmental, biologic, and disease mismanagement factors that u...

journal_title：Pediatric clinics of North America

authors： Federico MJ,Liu AH

更新日期：2003-06-01 00:00:00

abstract：:Beginning with a brief description of mature anatomic pathways and neurotransmitters in the "pain system," this article details their development in the human fetus, neonate, and child. Special emphasis is given to the basic mechanisms and physiologic effects of opioid analgesia. The clinical implications of these dat...

journal_title：Pediatric clinics of North America

authors： Anand KJ,Carr DB

更新日期：1989-08-01 00:00:00

abstract：:Derangements of fluid, electrolyte, and acid-base homeostasis are an inevitable part of acute renal failure. Understanding the pathophysiology of these disorders is essential to treating and preventing potentially life-threatening complications. Appropriate nutritional support is also an important part of management i...

journal_title：Pediatric clinics of North America

authors： Feld LG,Cachero S,Springate JE

更新日期：1990-04-01 00:00:00

abstract：:This article defines short bowel syndrome and reviews the pathophysiology, medical management, and surgical manipulations proposed to improve intestinal absorption. Emphasis is also placed on possible future methods of management. ...

journal_title：Pediatric clinics of North America

authors： Schwartz MZ,Maeda K

更新日期：1985-10-01 00:00:00

abstract：:Despite incomplete understanding of the etiology of Hodgkin's disease and its malignant cell of origin, the majority of children and adolescents diagnosed with Hodgkin's disease will be longterm survivors. Staging and treatment for pediatric Hodgkin's disease has evolved over the past 30 years in attempts to reduce la...

journal_title：Pediatric clinics of North America

authors： Hudson MM,Donaldson SS

更新日期：1997-08-01 00:00:00

abstract：:This brief overview serves as an introduction to the vast array of basic and clinical concepts that are pertinent to the basic understanding of ventricular fibrillation, its genesis, and its clinical management. ...

journal_title：Pediatric clinics of North America

authors： Fish FA

更新日期：2004-10-01 00:00:00

abstract：:Injury is the most important threat to the health of children in the United States and the leading cause of death after the first year of life. Injuries must be viewed as diseases that can be prevented by using principles of epidemiology, engineering, biomechanics, and health education. Effective preventative strategi...

journal_title：Pediatric clinics of North America

authors： Stylianos S,Eichelberger MR

更新日期：1993-12-01 00:00:00