Research priorities in epilepsy for the Asia-Oceanian region.

abstract：:The research literature is consistent in reporting somewhat less familial aggregation in partial than in generalized epilepsy. However, relatives of patients with partial seizures do appear to have higher seizure risks than relatives of controls, suggesting that genetic factors are important in at least some partial e...

journal_title：Epilepsia

authors： Ottman R

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:Higher homocysteine levels were found in actively drinking patients with alcohol dependence. Recent studies have shown that high homocysteine levels are associated with alcohol-withdrawal seizures. The aim of the present study was to calculate the best predictive cutoff value of plasma homocysteine levels in ac...

journal_title：Epilepsia

authors： Bleich S,Bayerlein K,Hillemacher T,Degner D,Kornhuber J,Frieling H

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:Transient hyperammonemia (THA) was reported to follow generalized convulsions without sufficient evidence to confirm the epileptic nature of those events. We aimed to determine if postictal THA can differentiate between different types of events as confirmed electroencephalographically using video-electroence...

journal_title：Epilepsia

authors： Albadareen R,Gronseth G,Landazuri P,He J,Hammond N,Uysal U

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:High-dose i.v. opioids (e.g., alfentanil, 50 microg/kg bolus) are known to increase the intraoperative reading of epileptiform activity during epilepsy surgery (ES), thereby facilitating localization of the epileptogenic zone (i.e., the site of ictal onset and initial seizure propagation). However, this phenome...

journal_title：Epilepsia

authors： Wass CT,Grady RE,Fessler AJ,Cascino GD,Lozada L,Bechtle PS,Marsh WR,Sharbrough FW,Schroeder DR

更新日期：2001-10-01 00:00:00

abstract：PURPOSE:To assess medical intractability in patients considered for restrictive epilepsy surgery. METHODS:Seventy-four patients received single drug treatment with carbamazepine (CBZ), phenytoin (PHT), and either phenobarbital (PB) or primidone (PRM). Medical intractability was established if seizure control was not o...

journal_title：Epilepsia

authors： Hermanns G,Noachtar S,Tuxhorn I,Holthausen H,Ebner A,Wolf P

更新日期：1996-07-01 00:00:00

abstract：PURPOSE:The role of the superior colliculus (SC) in seizure expression is controversial and appears to be dependent upon the epilepsy model. This study shows the effect of disconnection between SC deep layers and adjacent tissues in the expression of acute and kindling seizures. METHODS:Subcollicular transections, abl...

journal_title：Epilepsia

authors： Doretto MC,Cortes-de-Oliveira JA,Rossetti F,Garcia-Cairasco N

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:The annual prevalence of antiepileptic drug (AED) prescribing reported in the literature differs considerably among European countries due to use of different type of data sources, time periods, population distribution, and methodologic differences. This study aimed to measure prevalence of AED prescribing ac...

journal_title：Epilepsia

authors： de Groot MC,Schuerch M,de Vries F,Hesse U,Oliva B,Gil M,Huerta C,Requena G,de Abajo F,Afonso AS,Souverein PC,Alvarez Y,Slattery J,Rottenkolber M,Schmiedl S,Van Dijk L,Schlienger RG,Reynolds R,Klungel OH

更新日期：2014-05-01 00:00:00

abstract：:Kindling of the cingulate cortex in the Senegalese baboon Papio papio led to a protracted nonconvulsive seizure state characterized by immobile staring with (anterior cingulate, AC) or without (posterior cingulate, PC) widening of eyelids and neck flexion, followed by postictal visual searching behavior. Despite early...

journal_title：Epilepsia

authors： Wada JA,Tsuchimochi H

更新日期：1995-11-01 00:00:00

abstract：PURPOSE:Schizophrenia and epilepsy may share a mutual susceptibility. This study examined the bidirectional relation between the two disorders. METHODS:We used claims data obtained from the Taiwan National Health Insurance database to conduct retrospective cohort analyses. Analysis 1 compared 5,195 patients with incid...

journal_title：Epilepsia

authors： Chang YT,Chen PC,Tsai IJ,Sung FC,Chin ZN,Kuo HT,Tsai CH,Chou IC

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:Previous studies of patient-reported seizure precipitants have not evaluated whether different epilepsy syndromes are differentially affected. METHODS:Patients of a tertiary-care epilepsy center were consecutively surveyed with the use of a standardized questionnaire that lists precipitants that might trigger ...

journal_title：Epilepsia

authors： Frucht MM,Quigg M,Schwaner C,Fountain NB

更新日期：2000-12-01 00:00:00

abstract：:Seizures cannot be medically controlled in approximately 40% of people with epilepsy. Although we are beginning to understand how to better treat certain seizure types, we still do not know the regulatory events that determine antiepileptic drug resistance. Proposed pathoetiologic mechanisms include altered expression...

journal_title：Epilepsia

authors： Kobow K,El-Osta A,Blümcke I

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:To analyze the relationship between ictal electroencephalography (EEG) and ictal single-photon emission computed tomography (SPECT) and to evaluate the diagnostic usefulness of ictal SPECT as an independent presurgical evaluation technique. METHODS:Sixty-eight patients with temporal lobe epilepsy who underwent...

journal_title：Epilepsia

authors： Lee SK,Lee SH,Kim SK,Lee DS,Kim H

更新日期：2000-08-01 00:00:00

abstract：:Forty-eight patients with complex partial and/or tonic-clonic seizures were treated with an 8 p.m. single dose of carbamazepine slow release (CBZ-SR) monotherapy. The steady-state serum level profiles of carbamazepine (CBZ) and its metabolites CBZ-10,11-epoxide (CBZE) and 10,11-dihydro-CBZ-10,11-diole (CBZD) during 24...

journal_title：Epilepsia

authors： Stefan H,Schäfer H,Kuhnen C,Schneider S

更新日期：1988-09-01 00:00:00

abstract：PURPOSE:Hippocampal sclerosis (HS) is the most common pathologic finding in intractable temporal lobe epilepsy (TLE). In many patients, HS is accompanied by an extrahippocampal lesion (EHL). We sought to assess the lobar distribution and side of EHLs in relation to HS in a large consecutive series of patients presentin...

journal_title：Epilepsia

authors： Hofman PA,Fitt G,Mitchell LA,Jackson GD

更新日期：2011-04-01 00:00:00

abstract：:Periventricular nodular heterotopia (PNH) is a common structural malformation of cortical development. Mutations in the filamin A gene are frequent in familial cases with X-linked PNH. However, many cases with sporadic PNH remain genetically unexplained. Although medically refractory epilepsy often brings attention to...

journal_title：Epilepsia

authors： Montier L,Haneef Z,Gavvala J,Yoshor D,North R,Verla T,Van Ness PC,Drabek J,Goldman AM

更新日期：2019-10-01 00:00:00

abstract：:We explored Kentuckians' attitudes toward children with epilepsy. Questions compared respondents' attitudes about children with epilepsy, asthma, hyperactivity, and AIDS. Random digit dialing led to 617 completed interviews. The key questions asked concerned (a) how a pupil with each illness would alter the classroom ...

journal_title：Epilepsia

authors： Baumann RJ,Wilson JF,Wiese HJ

更新日期：1995-10-01 00:00:00

abstract：PURPOSE:Temporal lobe epilepsy is associated with the inflammatory process related to the basic mechanisms that lead to seizure susceptibility and brain damage. Platelet-activating factor (PAF), a potent, short-lived phospholipid mediator of inflammation, participates in physiologic signaling in the brain. However, aft...

journal_title：Epilepsia

authors： Musto AE,Samii M

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:To identify and define clinical and behavioral features of patients with adult-onset idiopathic generalized epilepsy (IGE). METHODS:We reviewed the charts of 313 IGE patients at the NYU Comprehensive Epilepsy Center over the past 5 years to identify patients with adult onset (18 years old or older). We exclude...

journal_title：Epilepsia

authors： Cutting S,Lauchheimer A,Barr W,Devinsky O

更新日期：2001-11-01 00:00:00

abstract：:The relationship between dreams and epilepsy is illustrated by two patients whose awake epileptic seizures and recurrent dreams during night sleep had similar content. In both of our cases the EEG showed right anterior temporal spike discharge, suggesting a role for the temporal lobe in the association between dreams ...

journal_title：Epilepsia

authors： Reami DO,Silva DF,Albuquerque M,Campos CJ

更新日期：1991-01-01 00:00:00

abstract：:We conducted a retrospective longitudinal self-controlled study of 124 adult patients treated with resective surgery for medically uncontrolled partial epilepsy from 1949 to 1988. Approximately 65% of the patients experienced > 95% reduction in seizure frequency, and 75% had worthwhile improvement of at least 75% seiz...

journal_title：Epilepsia

authors： Guldvog B,Løyning Y,Hauglie-Hanssen E,Flood S,Bjørnaes H

更新日期：1994-05-01 00:00:00

abstract：:Since it was originally described nearly 70 years ago, insular epilepsy has been increasingly recognized and may explain failures after apparently well-planned operations. We review the history of awareness of the phenomenon, techniques for its assessment, and its surgical management. Insular epilepsy can mimic featur...

journal_title：Epilepsia

authors： Laoprasert P,Ojemann JG,Handler MH

更新日期：2017-04-01 00:00:00

abstract：:Our understanding of the neural mechanisms of non-rapid eye movement sleep (NREM) is steadily increasing. Given the intriguing activation of paroxysmal activity during NREM sleep in patients with Landau-Kleffner syndrome (LKS), a thorough characterization of commonalities and differences between the neural correlates ...

journal_title：Epilepsia

authors： Mascetti L,Foret A,Bonjean M,Matarazzo L,Dang-Vu T,Maquet P

更新日期：2009-08-01 00:00:00

abstract：:Nicotinamide is a ligand of the benzodiazepine receptor and has been reported to have anticonvulsant activity. In addition, our previous clinical experience has raised the possibility that it may also potentiate the action of barbiturates. Therefore, we have examined the anticonvulsant activity and neurotoxicity of ni...

journal_title：Epilepsia

authors： Bourgeois BF,Dodson WE,Ferrendelli JA

更新日期：1983-04-01 00:00:00

abstract：:Polypharmacy is a widely employed treatment strategy in epilepsy, particularly for individuals with poorly controlled seizures. Drug combinations should be carefully considered to minimize the potential for unfavorable interactions. Older-generation antiepileptic drugs (AEDs) are well known for their pharmacokinetic i...

journal_title：Epilepsia

authors： Sills G,Brodie M

更新日期：2007-03-01 00:00:00

abstract：PURPOSE:Very fast activity was investigated on the ictal EEGs of epileptic spasms to elucidate the pathophysiology of West syndrome (WS) and related disorders from a novel point of view. METHODS:The traces of scalp ictal EEG of spasms temporally were expanded in 11 patients whose clinical diagnosis was symptomatic WS ...

journal_title：Epilepsia

authors： Kobayashi K,Oka M,Akiyama T,Inoue T,Abiru K,Ogino T,Yoshinaga H,Ohtsuka Y,Oka E

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:Nuclear receptors and cytochrome P450 (CYP) regulate hepatic metabolism of several drugs. Nuclear receptors are expressed at the neurovascular unit of patients with drug-resistant epilepsy. We studied whether glucocorticoid receptor (GR) silencing or inhibition in human epileptic brain endothelial cells (EPI-...

journal_title：Epilepsia

authors： Ghosh C,Hossain M,Mishra S,Khan S,Gonzalez-Martinez J,Marchi N,Janigro D,Bingaman W,Najm I

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the incidence of new onset epilepsy and associated risk factors in patients with periodic patterns on continuous electroencephalography (cEEG) during critical illness. METHODS:The local cEEG database and then medical records were reviewed from January 1, 2013 to June 30, 2013 to find adult patien...

journal_title：Epilepsia

authors： Punia V,Bena J,Krishnan B,Newey C,Hantus S

更新日期：2018-08-01 00:00:00

abstract：:Epilepsy is frequently associated with cognitive dysfunction. However, the reasons for this correlation are unclear. Possible influential factors include patient age; duration, frequency, etiology, and type of seizures; hereditary factors; psychosocial issues; and antiepileptic drug (AED) therapy. Whereas many of thes...

journal_title：Epilepsia

authors： Vining EP

更新日期：1987-01-01 00:00:00

abstract：PURPOSE:To clarify the differences between postictal mania (PIM) and postictal psychosis (PIP). METHODS:Five patients with PIM were compared to 17 patients with PIP, with respect to clinical, epileptological, electrophysiological, and neuroimaging features. PIM was distinguished from PIP by the symptoms observed in th...

journal_title：Epilepsia

authors： Nishida T,Kudo T,Inoue Y,Nakamura F,Yoshimura M,Matsuda K,Yagi K,Fujiwara T

更新日期：2006-12-01 00:00:00

abstract：PURPOSE:Neuropsychological studies suggest frontal lobe dysfunctions in patients with juvenile myoclonic epilepsy (JME). In this study we investigated whether an underlying mechanism could be a regional neuronal damage not visible with structural magnetic resonance (MR), but detectable with magnetic resonance spectrosc...

journal_title：Epilepsia

authors： Savic I,Lekvall A,Greitz D,Helms G

更新日期：2000-03-01 00:00:00