Abstract：
INTRODUCTION:We have previously shown that hyperbaric oxygen treatment (HBOT) increased insulin sensitivity in men who were obese or overweight, both with and without type 2 diabetes. The aim of this study was to test whether this insulin-sensitising effect is seen in hyperbaric air (HA). METHODS:Men with type 2 diabetes who were obese or overweight were randomised to two groups: HBOT (n = 13) or HA (n = 11). A hyperinsulinaemic euglycaemic glucose clamp (80 mU·m-2·min-1) was performed at baseline and during hyperbaric intervention. Both groups were compressed to 203 kPa (two atmospheres absolute) for 90 minutes followed by a linear 30-minute decompression. The HBOT group breathed oxygen via a hood while the HA group breathed chamber air. Insulin sensitivity was assessed from the glucose infusion rate (GIR) during the last 30 minutes in the hyperbaric chamber (SS1) and the first 30 minutes after exit (SS2). Data were analysed for within-group effect by paired student t-test and between-group effect by one-way ANOVA. RESULTS:HBOT increased GIR by a mean 26% at SS1 (P = 0.04) and 23% at SS2 (P = 0.018). There was no significant change in GIR during or after HA. A between-group effect was evident for the change in GIR at SS1 in HBOT vs HA (P = 0.036). CONCLUSIONS:The pathway by which insulin sensitivity is increased in men with type 2 diabetes requires the high oxygen partial pressures of HBOT and should be further investigated. Insulin sensitivity was not changed in hyperbaric air.
journal_name
Diving Hyperb Medjournal_title
Diving and hyperbaric medicineauthors
Wilkinson DC,Chapman IM,Heilbronn LKdoi
10.28920/dhm50.4.386-390subject
Has Abstractpub_date
2020-12-20 00:00:00pages
386-390issue
4eissn
1833-3516issn
2209-1491journal_volume
50pub_type
杂志文章,随机对照试验abstract：INTRODUCTION:The Diver Emergency Service (DES) in Australia provides specialised medical advice on diving incidents 24 hours a day to divers, dive operators, families and health professionals. It is operated from the Hyperbaric Medicine Unit of the Royal Adelaide Hospital where the physician-on-call also carries the DE...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2012-09-01 00:00:00
abstract：INTRODUCTION:Decompression sickness (DCS) results from a decrease in ambient pressure leading to supersaturation of tissues with inert gas and bubble formation. Perfluorocarbons (PFCs) are able to dissolve vast amounts of non-polar gases. Intravenous (IV) PFC emulsions reduce both morbidity and mortality associated wit...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2012-03-01 00:00:00
abstract：:Sphenoid sinus mucocele is a rare cystic lesion. It grows gradually and causes visual disturbances, ocular motility abnormalities and headache due to cavernous sinus compression. Sudden change in sinus cavity volume by a barotrauma may compress a mucocele and precipitate symptoms that may easily be confused with decom...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：10.28920/dhm50.2.168-172
更新日期：2020-06-30 00:00:00
abstract：:Cerebral arterial gas embolism (CAGE) is a feared complication of ambient depressurisation and can also be a complication of hydrogen peroxide ingestion. We present an unusual case of CAGE in a 57-year-old woman exposed to both of these risk factors. We describe her subsequent successful treatment with hyperbaric oxyg...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2016-06-01 00:00:00
abstract：:Recreational scuba diving is a popular leisure activity with the number of divers reaching several millions worldwide. Scuba diving represents a huge challenge for integrative physiology. In mammalian evolution, physiological reflexes developed to deal with lack of oxygen, rather than with an excess, which makes adapt...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章,评审
doi：
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND AND AIMS:Severe decompression sickness (DCS) is a multi-organ injury. This study investigated the preventive effects of rosiglitazone on liver injury following rapid decompression in mice and examined the underlying mechanisms. METHODS:Mice were randomly divided into four groups: a control group, vehicle gr...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：10.28920/dhm47.1.17-23
更新日期：2017-03-01 00:00:00
abstract：:Basic life support (BLS) in a diving bell (DB) or deck decompression chamber (DDC) is difficult due to the confined space and limited equipment. Retrieval of the unconscious diver into the DB requires the use of a pulley system. Once inside the bell, space limitations dictate that any resuscitative efforts are attempt...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2008-06-01 00:00:00
abstract：:We present a case of cerebral venous gas embolism. Our patient made a complete neurological recovery after hyperbaric oxygen therapy (HBOT). The principles of HBOT, compressing and eliminating air bubbles and decreasing Β-2 integrin function, thus improving microcirculation, can only be beneficial in a situation where...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2012-06-01 00:00:00
abstract：INTRODUCTION:We investigated in a prospective, observational trial the feasibility of using the Eustachian tube function test (ETFT) to measure the effect of repetitive pressure exposure during open seawater dives on Eustachian tube function. METHODS:The study included 28 adult divers during six consecutive days of di...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：10.28920/dhm47.4.216-222
更新日期：2017-12-01 00:00:00
abstract：:Two cases are presented of divers suffering epileptic seizure and loss of consciousness as a result of probable cerebral arterial gas embolism (CAGE). Both cases had apparently problem-free dives with no obvious provocation for CAGE, though one case may have been having repeated embolisms for some time in their diving...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2008-03-01 00:00:00
abstract：INTRODUCTION:Decompression illness (DCI) is associated with a right-to-left shunt, such as persistent foramen ovale (PFO), atrial septal defect (ASD) and pulmonary arteriovenous malformations. About one-quarter of the population have a PFO, but considerably less than one-quarter of divers suffer DCI. Our aim was to det...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2015-06-01 00:00:00
abstract：INTRODUCTION:Scuba diving is a big part of the tourism sector in Malta, and all the cases of decompression illness (DCI)are treated within the single hyperbaric referral centre in the country. METHODS:This retrospective analysis reviews all the medical records of divers with DCI in Malta within the 30-year period betw...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：10.28920/dhm49.3.161-166
更新日期：2019-09-30 00:00:00
abstract：BACKGROUND:Both negative wound pressure therapy (NPWT) and hyperbaric oxygen therapy (HBOT) are useful modalities in the treatment of problem wounds. However, none of the commercially available portable negative-pressure devices have been certified safe for use in a recompression chamber. Thus, the NPWT device is remov...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2011-09-01 00:00:00
abstract：INTRODUCTION:After a maximal apnoea, breath-hold divers must restore O2 levels and clear CO2 and lactic acid produced. High intensity interval training (HIIT) and inspiratory muscle training (IMT) could be employed with the aim of increasing recovery capacity. This study aimed to evaluate the relative effects of IMT ve...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章,随机对照试验
doi：10.28920/dhm50.4.318-324
更新日期：2020-12-20 00:00:00
abstract：INTRODUCTION:During a hyperbaric oxygen therapy (HBOT) session, every medical device that is used within the hyperbaric chamber is exposed to several hazards, including an increased ambient pressure and partial pressure of oxygen. In Europe, all medical devices marketed and/or sold for use in hyperbaric conditions must...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：10.28920/dhm49.2.137-140
更新日期：2019-06-30 00:00:00
abstract：:Inner-ear decompression sickness (DCS) is an incompletely understood and increasingly recognized condition in compressed-air divers. Previous reports show a high association of inner-ear DCS with persistent foramen ovale (PFO), suggesting that a moderate-to-severe right-to-left shunt might represent a major predisposi...
journal_title：Diving and hyperbaric medicine
pub_type： 信件
doi：
更新日期：2015-06-01 00:00:00
abstract：INTRODUCTION:In-water resuscitation has recently been proposed in the European resuscitation guidelines. Initiation of mechanical ventilation underwater might be considered when an immediate ascent to the surface is impossible or dangerous. The present study evaluated the feasibility of such ventilation underwater. ME...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2013-06-01 00:00:00
abstract：INTRODUCTION:An individual case review of diving-related deaths reported as occurring in Australia in 2006 was conducted as part of the Divers Alert Network Asia-Pacific (DAN AP) dive fatality reporting project. METHOD:The case studies were compiled using reports from witnesses, the police and coroners. In each case, ...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2011-06-01 00:00:00
abstract：INTRODUCTION:In studies of decompression procedures, ultrasonically detected venous gas emboli (VGE) are commonly used as a surrogate outcome if decompression sickness (DCS) is unlikely to be observed. There is substantial variability in observed VGE grades, and studies should be designed with sufficient power to detec...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2014-03-01 00:00:00
abstract：:Commercial or occupational breath-hold (BH) harvest divers along the coast and islands of Japan are collectively called Ama divers. Repetitive BH diving by Ama divers may place them at risk of developing neurological decompression sickness (DCS). We report a 74-year-old Ama diver who demonstrated right hemiparesis dur...
journal_title：Diving and hyperbaric medicine
pub_type：
doi：10.28920/dhm48.4.262-263
更新日期：2018-12-24 00:00:00
abstract：:Divers from many countries travel to explore various diving sites worldwide. In 2005, the Divers Alert Network (DAN) wrote guidelines for recreational diving and diabetes mellitus, but there is no up-to-date consensus or adoption of international guidelines on diabetes and diving. There are also large differences betw...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2012-12-01 00:00:00
abstract：INTRODUCTION:Running out of air, buoyancy problems and rapid ascents are known risk factors for diving morbidity and mortality. The effects of the diving environment and equipment and the influence of individual diver characteristics on these risks were studied. METHODS:Between 1995 and 2004, Project Dive Exploration ...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:Since 2009, the United Kingdom diving incident data show an increasing number of fatalities in the over-50s age group. Previous studies also suggest some divers take cardiac medications. Since 2001, diving medicals have not been mandatory for UK sport divers. Instead, an annual medical self-certification for...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2015-09-01 00:00:00
abstract：:Cerebral arterial gas embolism (CAGE) from breath-holding or inadequate exhalation during ascent is a well-recognised complication of scuba diving. It does not usually occur with breath-hold (BH) diving in those with normal lungs, as the volume of gas in the lungs on surfacing cannot exceed what it was on leaving the ...
journal_title：Diving and hyperbaric medicine
pub_type：
doi：10.28920/dhm49.4.304-305
更新日期：2019-12-20 00:00:00
abstract：INTRODUCTION:The adverse effects of hyperbaric oxygen (HBO) on cardiac physiology are considered a potential hazard during the treatment of some patients. The haemodynamic effects of HBO are poorly understood and the incompatibility of electrical equipment inside the chamber has made assessment difficult. At Fremantle ...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2014-09-01 00:00:00
abstract：:Exposure to hyperoxia is associated with oxidative stress and is known to cause inflammation in the lung and the airways. Exhaled nitric oxide concentration (FENO) is a marker of some inflammatory processes in the lung and airways, and is reduced immediately after a single session of hyperbaric oxygen (HBO) exposure. ...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2009-06-01 00:00:00
abstract：INTRODUCTION:This study identified pre-existing medical conditions among scuba diving fatalities in Australia from 2001 to 2013, inclusive, and assessed whether these conditions likely contributed to the deaths. METHODS:The National Coronial Information System (NCIS) was searched for scuba diving-related cases during ...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：10.28920/dhm50.2.98-104
更新日期：2020-06-30 00:00:00
abstract：:Decompression illness (DCI) is a syndrome with diverse clinical manifestations but in which cardiac symptoms are rare. In the presence of cardiac symptoms, the necessity to rule out an acute coronary syndrome (ACS) which requires prompt treatment may result in delay to appropriate recompression treatment. We describe ...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2013-12-01 00:00:00
abstract：INTRODUCTION:Scuba diving involves risks, and candidates in Australia usually have a medical evaluation prior to undertaking a diving course. Hyperbaric physicians act as secondary referral practitioners for these assessments. This study aimed to identify reasons for these secondary referrals, and document the assessme...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2010-09-01 00:00:00
abstract：INTRODUCTION:Various prescribed and over-the-counter medications may theoretically be incompatible with the diving environment. Anecdotally, it is known divers regularly take medications around the time of their diving activities for different health conditions, possibly ignoring the recommendations not to do so. As pa...
journal_title：Diving and hyperbaric medicine
pub_type： 杂志文章
doi：
更新日期：2011-03-01 00:00:00
