Abstract:
INTRODUCTION:In studies of decompression procedures, ultrasonically detected venous gas emboli (VGE) are commonly used as a surrogate outcome if decompression sickness (DCS) is unlikely to be observed. There is substantial variability in observed VGE grades, and studies should be designed with sufficient power to detect an important effect. METHODS:Data for estimating sample size requirements for studies using VGE as an outcome is provided by a comparison of two decompression schedules that found corresponding differences in DCS incidence (3/192 [DCS/dives] vs. 10/198) and median maximum VGE grade (2 vs. 3, P < 0.0001, Wilcoxon test). Sixty-two subjects dived each schedule at least once, accounting for 183 and 180 man-dives on each schedule. From these data, the frequency with which 10,000 randomly resampled, paired samples of maximum VGE grade were significantly different (paired Wilcoxon test, one-sided P ⋜ 0.05 or 0.025) in the same direction as the VGE grades of the full data set were counted (estimated power). Resampling was also used to estimate power of a Bayesian method that ranks two samples based on DCS risks estimated from the VGE grades. RESULTS:Paired sample sizes of 50 subjects yielded about 80% power, but the power dropped to less than 50% with fewer than 30 subjects. CONCLUSIONS:Comparisons of VGE grades that fail to find a difference between paired sample sizes of 30 or fewer must be interpreted cautiously. Studies can be considered well powered if the sample size is 50 even if only a one-grade difference in median VGE grade is of interest.
journal_name
Diving Hyperb Medjournal_title
Diving and hyperbaric medicineauthors
Doolette DJ,Gault KA,Gutvik CRsubject
Has Abstractpub_date
2014-03-01 00:00:00pages
14-9issue
1eissn
1833-3516issn
2209-1491journal_volume
44pub_type
杂志文章abstract::We present a case of cerebral venous gas embolism. Our patient made a complete neurological recovery after hyperbaric oxygen therapy (HBOT). The principles of HBOT, compressing and eliminating air bubbles and decreasing Β-2 integrin function, thus improving microcirculation, can only be beneficial in a situation where...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章
doi:
更新日期:2012-06-01 00:00:00
abstract::Livedoid vasculopathy is a painful, ulcerating condition of the lower legs, ankles and feet with the typical histological feature of hyalinising vascular change of dermal blood vessels with minimal inflammation. Therapeutic interventions have been diverse and varyingly successful. We report a biopsy-proven case in a 2...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章
doi:
更新日期:2013-03-01 00:00:00
abstract::Decompression illness (DCI) is a syndrome with diverse clinical manifestations but in which cardiac symptoms are rare. In the presence of cardiac symptoms, the necessity to rule out an acute coronary syndrome (ACS) which requires prompt treatment may result in delay to appropriate recompression treatment. We describe ...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章
doi:
更新日期:2013-12-01 00:00:00
abstract::Firstly I would like to thank SPUMS members for making me a Life Member of SPUMS; I was surprised and greatly honoured by the award. I also want to confirm and expand on the findings on carbon dioxide absorbents reported by David Harvey et al. For about 35 years, I was the main player in deciding which absorbent went ...
journal_title:Diving and hyperbaric medicine
pub_type: 评论,信件
doi:
更新日期:2016-09-01 00:00:00
abstract::Dear Editor, By focussing on the details of the Watson case, I believe Bryan Walpole has missed the thrust of my earlier letter. I agree this was a complex case, which is why I deliberately avoided the murky specifics in order to consider the 'big-picture' ramifications of the judgement. My concerns relate to the pote...
journal_title:Diving and hyperbaric medicine
pub_type: 信件
doi:
更新日期:2011-12-01 00:00:00
abstract:INTRODUCTION:Decompression sickness (DCS) results from a decrease in ambient pressure leading to supersaturation of tissues with inert gas and bubble formation. Perfluorocarbons (PFCs) are able to dissolve vast amounts of non-polar gases. Intravenous (IV) PFC emulsions reduce both morbidity and mortality associated wit...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章
doi:
更新日期:2012-03-01 00:00:00
abstract::Commercial or occupational breath-hold (BH) harvest divers along the coast and islands of Japan are collectively called Ama divers. Repetitive BH diving by Ama divers may place them at risk of developing neurological decompression sickness (DCS). We report a 74-year-old Ama diver who demonstrated right hemiparesis dur...
journal_title:Diving and hyperbaric medicine
pub_type:
doi:10.28920/dhm48.4.262-263
更新日期:2018-12-24 00:00:00
abstract:BACKGROUND:Colorectal cancer is the third most common form of cancer and colorectal surgery is the treatment of choice in local disease. Anastomotic leakage following colorectal surgery is a major complication with a high incidence and mortality. Adjuvant hyperbaric oxygen treatment (HBOT) may be associated with reduct...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章,meta分析
doi:10.28920/dhm48.3.173-185
更新日期:2018-09-30 00:00:00
abstract:INTRODUCTION:After a maximal apnoea, breath-hold divers must restore O2 levels and clear CO2 and lactic acid produced. High intensity interval training (HIIT) and inspiratory muscle training (IMT) could be employed with the aim of increasing recovery capacity. This study aimed to evaluate the relative effects of IMT ve...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章,随机对照试验
doi:10.28920/dhm50.4.318-324
更新日期:2020-12-20 00:00:00
abstract::Two cases are presented of divers suffering epileptic seizure and loss of consciousness as a result of probable cerebral arterial gas embolism (CAGE). Both cases had apparently problem-free dives with no obvious provocation for CAGE, though one case may have been having repeated embolisms for some time in their diving...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章
doi:
更新日期:2008-03-01 00:00:00
abstract::Gas micronuclei are gas-filled voids in liquids from which bubbles can form at low gas supersaturation. If water is depleted of gas micronuclei, high gas supersaturation is required for bubble formation. This high gas supersaturation is required in part to overcome the Laplace pressure at the point of transition from ...
journal_title:Diving and hyperbaric medicine
pub_type: 信件
doi:10.28920/dhm49.1.64
更新日期:2019-03-31 00:00:00
abstract:INTRODUCTION:In-water resuscitation has recently been proposed in the European resuscitation guidelines. Initiation of mechanical ventilation underwater might be considered when an immediate ascent to the surface is impossible or dangerous. The present study evaluated the feasibility of such ventilation underwater. ME...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章
doi:
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Both negative wound pressure therapy (NPWT) and hyperbaric oxygen therapy (HBOT) are useful modalities in the treatment of problem wounds. However, none of the commercially available portable negative-pressure devices have been certified safe for use in a recompression chamber. Thus, the NPWT device is remov...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2011-09-01 00:00:00
abstract::Cerebral arterial gas embolism (CAGE) is a feared complication of ambient depressurisation and can also be a complication of hydrogen peroxide ingestion. We present an unusual case of CAGE in a 57-year-old woman exposed to both of these risk factors. We describe her subsequent successful treatment with hyperbaric oxyg...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章
doi:
更新日期:2016-06-01 00:00:00
abstract:INTRODUCTION:This study identified pre-existing medical conditions among scuba diving fatalities in Australia from 2001 to 2013, inclusive, and assessed whether these conditions likely contributed to the deaths. METHODS:The National Coronial Information System (NCIS) was searched for scuba diving-related cases during ...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章
doi:10.28920/dhm50.2.98-104
更新日期:2020-06-30 00:00:00
abstract::It is increasingly common for recreational scuba divers to use breathing mixtures enriched with additional oxygen ('nitrox' or 'enriched air nitrogen') and for technical divers to be exposed to elevated partial pressures of oxygen for prolonged periods of time. The National Oceanic and Atmospheric Administration oxyge...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章
doi:
更新日期:2008-06-01 00:00:00
abstract:INTRODUCTION:Scuba diving is a big part of the tourism sector in Malta, and all the cases of decompression illness (DCI)are treated within the single hyperbaric referral centre in the country. METHODS:This retrospective analysis reviews all the medical records of divers with DCI in Malta within the 30-year period betw...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章
doi:10.28920/dhm49.3.161-166
更新日期:2019-09-30 00:00:00
abstract:BACKGROUND:Since 2009, the United Kingdom diving incident data show an increasing number of fatalities in the over-50s age group. Previous studies also suggest some divers take cardiac medications. Since 2001, diving medicals have not been mandatory for UK sport divers. Instead, an annual medical self-certification for...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章
doi:
更新日期:2015-09-01 00:00:00
abstract::In an emergency, life support can be provided during recompression or hyperbaric oxygen therapy using very basic equipment, provided the equipment is hyperbaric-compatible and the clinicians have appropriate experience. For hyperbaric critical care to be provided safely on a routine basis, however, a great deal of pre...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章,评审
doi:
更新日期:2015-03-01 00:00:00
abstract::Divers suspected of suffering decompression illness (DCI) in locations remote from a recompression chamber are sometimes treated with in-water recompression (IWR). There are no data that establish the benefits of IWR compared to conventional first aid with surface oxygen and transport to the nearest chamber. However, ...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章,评审
doi:10.28920/dhm48.2.84-95
更新日期:2018-06-30 00:00:00
abstract::Recreational scuba diving is a popular leisure activity with the number of divers reaching several millions worldwide. Scuba diving represents a huge challenge for integrative physiology. In mammalian evolution, physiological reflexes developed to deal with lack of oxygen, rather than with an excess, which makes adapt...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章,评审
doi:
更新日期:2013-09-01 00:00:00
abstract::It has been shown that a single bout of exercise performed 20 hours prior to hyperbaric exposure reduces bubble formation and increases survival in rats. Heat shock proteins (HSPs) are stress proteins expressed in cells that are exposed to different stressors. HSPs are known to protect cells, by binding to proteins an...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章
doi:
更新日期:2008-12-01 00:00:00
abstract:INTRODUCTION:The adverse effects of hyperbaric oxygen (HBO) on cardiac physiology are considered a potential hazard during the treatment of some patients. The haemodynamic effects of HBO are poorly understood and the incompatibility of electrical equipment inside the chamber has made assessment difficult. At Fremantle ...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章
doi:
更新日期:2014-09-01 00:00:00
abstract::The South Pacific Underwater Medicine Society (SPUMS) diving medical for recreational scuba divers was last reviewed in 2011. From 2011 to 2019, considerable advancements have occurred in cardiovascular risk assessment relevant to divers. The SPUMS 48th (2019) Annual Scientific Meeting theme was cardiovascular risk as...
journal_title:Diving and hyperbaric medicine
pub_type: 指南
doi:10.28920/dhm50.3.273-277
更新日期:2020-09-30 00:00:00
abstract:INTRODUCTION:We have previously shown that hyperbaric oxygen treatment (HBOT) increased insulin sensitivity in men who were obese or overweight, both with and without type 2 diabetes. The aim of this study was to test whether this insulin-sensitising effect is seen in hyperbaric air (HA). METHODS:Men with type 2 diabe...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章,随机对照试验
doi:10.28920/dhm50.4.386-390
更新日期:2020-12-20 00:00:00
abstract::Sphenoid sinus mucocele is a rare cystic lesion. It grows gradually and causes visual disturbances, ocular motility abnormalities and headache due to cavernous sinus compression. Sudden change in sinus cavity volume by a barotrauma may compress a mucocele and precipitate symptoms that may easily be confused with decom...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章
doi:10.28920/dhm50.2.168-172
更新日期:2020-06-30 00:00:00
abstract:INTRODUCTION:Transcutaneous oximetry measurement (TCOM) is a non-invasive method of determining oxygen tension at the skin level using heated electrodes. AIM:To compare TCOM values generated by different machines and to establish lower limb TCOM values in a cohort of healthy individuals younger than 40 years of age. ...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章
doi:10.28920/dhm47.2.82-87
更新日期:2017-06-01 00:00:00
abstract::Inner-ear decompression sickness (DCS) is an incompletely understood and increasingly recognized condition in compressed-air divers. Previous reports show a high association of inner-ear DCS with persistent foramen ovale (PFO), suggesting that a moderate-to-severe right-to-left shunt might represent a major predisposi...
journal_title:Diving and hyperbaric medicine
pub_type: 信件
doi:
更新日期:2015-06-01 00:00:00
abstract::Divers are exposed to circulatory stress that directly affects the endothelial lining of blood vessels, and even asymptomatic dives are associated with inflammatory responses, microparticle release and endothelial dysfunction. As humans age, there is a relative increase in the risk of cardiovascular disease, attribute...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章,评审
doi:
更新日期:2015-12-01 00:00:00
abstract:INTRODUCTION:During a hyperbaric oxygen therapy (HBOT) session, every medical device that is used within the hyperbaric chamber is exposed to several hazards, including an increased ambient pressure and partial pressure of oxygen. In Europe, all medical devices marketed and/or sold for use in hyperbaric conditions must...
journal_title:Diving and hyperbaric medicine
pub_type: 杂志文章
doi:10.28920/dhm49.2.137-140
更新日期:2019-06-30 00:00:00