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Identification and characterization of β-sitosterol target proteins.

Abstract：

:β-Sitosterol is the most abundant plant sterol in the human diet. It is also the major component of several traditional medicines, including saw palmetto and devil's claw. Although β-sitosterol is effective against enlarged prostate in human clinical trials and has anti-cancer and anti-inflammatory activities, the mechanisms of action are poorly understood. Here, we report the identification of two new binding proteins for β-sitosterol that may underlie its beneficial effects.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Lomenick B,Shi H,Huang J,Chen C

doi

10.1016/j.bmcl.2015.03.007

subject

Has Abstract

pub_date

2015-11-01 00:00:00

pages

4976-4979

issue

21

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(15)00203-6

journal_volume

25

pub_type

杂志文章

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