Abstract:
:The aim of this study was to identify factors associated with prevention of mother-to-child transmission (PMTCT) in an area of Kenya with widely accessible free PMTCT services. A matched case-control study was conducted at 31 public facilities in western Kenya. HIV-infected mothers with infants aged 6 weeks to 6 months were interviewed and medical charts were reviewed. Cases were mothers of infants with a definitive diagnosis of HIV. Controls were mothers of infants testing HIV negative. Cases and controls were matched in a 1:3 ratio on socio-demographic factors. Fifty cases and 135 controls were enrolled. Conditional (matched) logistic regression analysis was conducted. Odds of being a case were higher for women who first learned their HIV status during pregnancy [OR:2.85, 95%CI:1.41-5.78], did not adhere to antiretroviral therapy (ART) [OR:3.35, 95%CI:1.48-7.58], or had a home delivery [OR:2.42, 95%CI:1.01-5.80]. Based on medical record review, cases had higher odds of their provider not following guidelines for prescription of ART for mothers [OR:8.61, 95%CI:2.83-26.15] and infants [OR:9.72, 95%CI:2.75-34.37]. Stigma from the community [OR:0.37, 95% CI:0.14-1.02] or facility [OR:0.38, 95%CI:0.04-3.41], did not increase the odds of MTCT. Poor adherence to PMTCT guidelines and recommendations by both infected women and health care providers hamper efforts to attain elimination of MTCT.
journal_name
AIDS Patient Care STDSjournal_title
AIDS patient care and STDsauthors
Onono M,Owuor K,Turan J,Bukusi EA,Gray GE,Cohen CRdoi
10.1089/apc.2014.0181subject
Has Abstractpub_date
2015-04-01 00:00:00pages
204-11issue
4eissn
1087-2914issn
1557-7449journal_volume
29pub_type
杂志文章abstract::Treatment with highly active antiretroviral therapy (HAART) decreases morbidity and mortality for persons with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) and reduces costs of care. Yet many patients for whom HAART is indicated do not receive it. This study investigated the reasons why c...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/10872910151133701
更新日期:2001-04-01 00:00:00
abstract::There are few studies that compare opportunistic infection (OI) rates for U.S.-born, Mexican-born, and Central American-born Latinos in the pre- or post-highly active antiretroviral therapy (HAART) era. Data on 803 Latino persons in treatment for HIV infection in Los Angeles, California, were examined to evaluate diff...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/108729103322108148
更新日期:2003-06-01 00:00:00
abstract::Combination antiretroviral therapy (ART) has markedly improved survival in HIV-infected patients, but not without significant adverse effects including ART-associated dyslipdemia and insulin resistance, which may in part contribute to an increased risk of cardiovascular events. Other contributing factors to cardiovasc...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2008.0142
更新日期:2009-04-01 00:00:00
abstract::Although more than 90% of youth perinatally infected with HIV live in sub-Saharan Africa, little is known about the psychosocial factors that impact their wellbeing, or how these youth cope with these challenges. The purpose of this study was to identify the psychosocial challenges and coping strategies among perinata...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2014.0222
更新日期:2015-02-01 00:00:00
abstract::While many factors contribute to mother-to-child transmission (MTCT) of HIV-1, maternal plasma HIV-1 RNA viral load (RNA-VL) has been consistently found as the main risk factor, including when antiretroviral prophylaxis was used to prevent MTCT. However the predictive value of RNA-VL is poor. A recent study of HIV-1-p...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1089/apc.2006.0169
更新日期:2007-09-01 00:00:00
abstract::Addressing women's low uptake of HIV pre-exposure prophylaxis (PrEP) requires improved understanding of their product preferences. Such preferences should be contextualized according to other aspects of their reproductive health, including their contraception practices. We investigated women's preferences across 10 Pr...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2019.0242
更新日期:2020-03-01 00:00:00
abstract::Hepatitis C virus (HCV) and HIV share the same parenteral routes of transmission. This common epidemiology explains the high frequency of combined infections by HCV and HIV. The aim of this review is to clarify some important issues dealing with the reciprocal impact of HIV and HCV-associated infections, including the...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章,评审
doi:10.1089/apc.1998.12.11
更新日期:1998-01-01 00:00:00
abstract::Pregnant women living with HIV are at risk for loss to follow-up and viral rebound after delivery. We conducted a retrospective cohort study of women with HIV who delivered at Parkland Hospital, Dallas, to identify factors associated with postpartum loss to HIV care 1 year after delivery. Logistic regression was used ...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2018.0117
更新日期:2019-01-01 00:00:00
abstract::Eye disease is a well-documented complication of HIV infection. Opportunistic infections generally comprised the majority of pre-antiretroviral therapy (ART) eye complications. With the introduction of ART, opportunistic infections diminished. However, early ART regimens were cumbersome regarding side effects and pill...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2013.0258
更新日期:2014-02-01 00:00:00
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journal_title:AIDS patient care and STDs
pub_type: 杂志文章,评审
doi:10.1089/10872910050206559
更新日期:2000-12-01 00:00:00
abstract::This article discusses some of the issues specifically associated with women and HIV. The myth is that women do not get AIDS and that lesbians do not get AIDS either. It also explores the unique sociocultural context in which HIV-infected women exist. The hope is to put faces on the numbers that are increasing each da...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.1999.13.119
更新日期:1999-02-01 00:00:00
abstract::This article argues that enhancing efficacious social networks or developing new adaptive social ties for HIV-infected individuals without adequate social resources may enhance their adaptive response to the disease and its treatment. It further suggests that the success of an adaptive response to the disease may to s...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章,评审
doi:10.1089/108729100750018326
更新日期:2000-10-01 00:00:00
abstract::Despite recent clinical guidelines recommending early initiation and widespread use of antiretroviral therapy (ART), many HIV-infected individuals are not receiving ART-in particular low-income, minority substance users. Few studies have examined psychological, as opposed to structural, factors related to not receivin...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2013.0120
更新日期:2013-09-01 00:00:00
abstract::This exploratory study examined patient-provider communication dynamics regarding adherence to highly active antiretroviral therapy (HAART) and protective sexual behavior among people living with HIV/AIDS (PLWHA). We conducted 20 direct observations of routine consultations between PLWHA and care providers in two larg...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2006.20.637
更新日期:2006-09-01 00:00:00
abstract::For treatment of HIV/AIDS in jails and prisons to be effective, these institutions must identify as many HIV-positive inmates as they can. We compare HIV status among a drug-addicted jail population determined through a physical examination and a voluntary HIV testing program, with self-reported status in an interview...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2006.20.93
更新日期:2006-02-01 00:00:00
abstract::Kaposi's sarcoma of the breast is extremely rare. We report a case of a patient with AIDS presenting with Kaposi's sarcoma localized to the breast and review another published case of a patient with AIDS and disseminated cutaneous Kaposi's sarcoma with breast involvement. Although rare, the diagnosis should be conside...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/108729100318019
更新日期:2000-02-01 00:00:00
abstract::With the approval of rapid HIV testing and the expected broader use of this technology, community-based organizations incorporating its use face both opportunities and challenges. The primary advantage of rapid testing is the ability to dramatically increase the number of individuals who become aware of their HIV stat...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/108729104322740875
更新日期:2004-01-01 00:00:00
abstract::Adherence to antiretroviral regimens is thought to be imperative for HIV-positive patients. However, little is known about health care professionals' willingness to discuss adherence with patients, nor what barriers, if any, may impede their adherence communication. The aims of the study were to examine physicians' be...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/108729100438854
更新日期:2000-09-01 00:00:00
abstract::In HIV/AIDS, symptoms of depression or post-traumatic stress may interfere with important self-care behaviors such as the ability to adhere to one's medical treatment regimen. However, these problems may frequently go undetected in HIV care settings. The present study used brief self-report screening measures of depre...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1089/apc.2007.0069
更新日期:2008-04-01 00:00:00
abstract::Imaging is often vital in the diagnosis and staging of acquired immune deficiency syndrome (AIDS) patients with regard to infections and malignancies. Non-Hodgkin's lymphoma is an AIDS-defining illness and a common AIDS-related malignancy. These lymphomas are usually high-grade immunoblastic, primary central nervous s...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/10872910260196422
更新日期:2002-08-01 00:00:00
abstract::Health information technology (HIT) offers the potential to improve care for persons living with HIV. Provider satisfaction with HIT is essential to realize benefits, yet its evaluation presents challenges. An HIV-specific, electronic clinical management and reporting system was implemented in Louisiana's eight HIV cl...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2008.0053
更新日期:2009-02-01 00:00:00
abstract::Limited knowledge exists regarding parenting efficacy interventions for mothers living with HIV (MLH). This study evaluated the impact of a supportive group intervention on lowering parenting stress among MLH. Eighty MLH were randomized to a parenting (N=34) or health focused (control) (N=46) group intervention. Pre- ...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章,随机对照试验
doi:10.1089/apc.2014.0187
更新日期:2015-04-01 00:00:00
abstract::Depression is highly prevalent among HIV-infected patients, yet little is known about the quality of HIV providers' depression treatment practices. We assessed depression treatment practices of 72 HIV providers at three academic medical centers in 2010-2011 with semi-structured interviews. Responses were compared to n...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2012.0406
更新日期:2013-03-01 00:00:00
abstract::Forty-six Chinese patients with symptomatic human immunodeficiency virus (HIV) participated in a comparative study assessing the effectiveness of cognitive-behavioral group therapy (CBT) and peer support/counseling group therapy (PSC) in relation to improving mood and quality of life and decreasing uncertainty in illn...
journal_title:AIDS patient care and STDs
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1089/10872910252806135
更新日期:2002-02-01 00:00:00
abstract::The purpose of this study was to examine retrospective reports of rates of HIV disclosure to family and friends over a 15-year time span. Participants included 116 HIV-positive men who have sex with men recruited primarily from an AIDS clinical trials unit associated with a large Midwestern university. Disclosure data...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2005.0002
更新日期:2007-07-01 00:00:00
abstract::We reviewed the short-term response to and safety of protease inhibitor (PI) therapy in HIV-infected children by performing a retrospective chart review of open-label PI containing combination therapy at two urban pediatric HIV centers. Seventy HIV-infected children received 101 PI containing antiretroviral therapy (A...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/10872910050193761
更新日期:2000-11-01 00:00:00
abstract::HIV infection and substance use disorders are chronic diseases with complex contributions to health-related quality of life (HRQOL). We conducted a cross-sectional survey of 951 HIV-infected adults receiving care at 14 HIV Research Network sites in 2003 to estimate associations between HRQOL and specific substance use...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2008.0005
更新日期:2008-11-01 00:00:00
abstract::The HIV care continuum illustrates steps needed to reach HIV viral suppression, including retention in care. The continuum's retention measure does not account for gaps or reengagement in care and thus provides an incomplete picture of long-term engagement. We used a claims database to determine the proportion of priv...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2016.0188
更新日期:2016-11-01 00:00:00
abstract::HIV vaccine availability does not guarantee uptake. Given suboptimal uptake of highly efficacious and already accessible vaccines in the United States, low vaccine coverage in the developing world, and the expectation that initial HIV vaccines will be only partially efficacious, the public health community will face f...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章,评审
doi:10.1089/apc.2004.18.691
更新日期:2004-12-01 00:00:00
abstract::Despite the importance of timely entry into care after HIV diagnosis, the timing of care entry has not been described recently in a large, diverse population of persons with HIV. Dates of HIV diagnosis and entry into HIV care were obtained by interview of HIV-infected adults, most of whom had entered care for HIV, in ...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2008.0213
更新日期:2009-09-01 00:00:00