Abstract:
:Human immunodeficiency virus type 1 (HIV-1)-seropositive patients are at risk for the development of a variety of acute and chronic renal diseases. The most common cause of chronic renal failure in HIV-1-seropositive patients is HIV-associated nephropathy (HIVAN). HIVAN occurs almost exclusively in black patients and the majority of published cases are of patients who present with acquired immunodeficiency syndrome (AIDS). This disease is currently the third leading cause of end-stage renal disease in blacks aged 20-64. Because HIV-1-seropositive patients may develop a wide variety of acute and chronic renal diseases, definitive diagnosis requires renal biopsy. Emerging data suggest a direct role of HIV-1 infection of kidney cells in the pathogenesis of HIVAN. There have been no well-controlled clinical trials in the treatment of HIVAN. The therapeutic agents with the most promise are angiotensin-converting enzyme inhibitors and antiretroviral medications. Long-term renal prognosis may be changing in the setting of improved aggressive antiretroviral therapy. Patient survival is determined primarily by the stage of HIV-1 infection. In this article, we present the case history of a patient who developed HIVAN. We then review the current literature concerning the epidemiology, differential diagnosis, etiology, and treatment of HIVAN.
journal_name
AIDS Patient Care STDSjournal_title
AIDS patient care and STDsauthors
Ross MJ,Klotman PE,Winston JAdoi
10.1089/10872910050206559subject
Has Abstractpub_date
2000-12-01 00:00:00pages
637-45issue
12eissn
1087-2914issn
1557-7449journal_volume
14pub_type
杂志文章,评审abstract::Gastrointestinal ulcerations in persons infected with HIV have many causes, the most common being opportunistic infections and neoplasms. Recently, idiopathic ulcerative lesions of the colon and rectum have been described. Two cases are reported of idiopathic colonic and anorectal inflammation and ulceration which fai...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.1998.12.903
更新日期:1998-12-01 00:00:00
abstract::Risk behaviors associated with sexually transmitted infections (STIs) among people living with HIV (PLWH) have not been well characterized in the US military. We identified risk behaviors associated with a new STI in this population after the repeal of "Don't Ask, Don't Tell." US Military HIV Natural History Study par...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2020.0095
更新日期:2020-12-01 00:00:00
abstract::Complications of Bacillus Calmette-Guerin (BCG) vaccination have been reported in immunocompetent as well as in immunocompromised individuals. Severe and/or late complications have been associated with impairment of cell-mediated immunity. A case of BCG lymphadenitis in a vertically infected HIV-positive boy 9.5 years...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.1998.12.677
更新日期:1998-09-01 00:00:00
abstract::In the United States, gay, bisexual, and other men who have sex with men (GBMSM) are disproportionately affected by the HIV/AIDS epidemic. Despite great strides in HIV prevention, including biobehavioral HIV prevention strategies such as pre-exposure prophylaxis and treatment as prevention, there has been relatively l...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2017.0244
更新日期:2018-01-01 00:00:00
abstract::Adolescents of parents infected with HIV/AIDS (HIV-affected adolescents) were recruited from August 1993 to March 1995 to examine their depression as a function of their social support. Adolescent depression and the size, frequency of contact, satisfaction, negative role model influence, and positive social support we...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2006.0066
更新日期:2007-06-01 00:00:00
abstract::Prisoner reentry is a stressful process and many prisoners return to behaviors that led to incarceration upon community reentry. We assess how individual-level vulnerabilities interact with system-level barriers that impact the community reentry process. An additional area explored was the impact of reentry services o...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2010.0372
更新日期:2011-08-01 00:00:00
abstract::Imaging is often vital in the diagnosis and staging of acquired immune deficiency syndrome (AIDS) patients with regard to infections and malignancies. Non-Hodgkin's lymphoma is an AIDS-defining illness and a common AIDS-related malignancy. These lymphomas are usually high-grade immunoblastic, primary central nervous s...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/10872910260196422
更新日期:2002-08-01 00:00:00
abstract::There are few studies that compare opportunistic infection (OI) rates for U.S.-born, Mexican-born, and Central American-born Latinos in the pre- or post-highly active antiretroviral therapy (HAART) era. Data on 803 Latino persons in treatment for HIV infection in Los Angeles, California, were examined to evaluate diff...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/108729103322108148
更新日期:2003-06-01 00:00:00
abstract::This article argues that enhancing efficacious social networks or developing new adaptive social ties for HIV-infected individuals without adequate social resources may enhance their adaptive response to the disease and its treatment. It further suggests that the success of an adaptive response to the disease may to s...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章,评审
doi:10.1089/108729100750018326
更新日期:2000-10-01 00:00:00
abstract::The average reported age of sexual debut for youth in the United States is 14.4 years, with approximately 7% reporting their sexual debut prior to age 13. While the research literature on sexual debut for youth addresses gender and ethnic differences (with males and African-American youth experiencing earlier sexual d...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2011.9879
更新日期:2011-08-01 00:00:00
abstract::With the advent of the highly active antiretroviral therapy (HAART), adherence became one of the key issues within the behavioral management of the treatment of human immunodeficiency virus (HIV) infection. One of the central limitations in studying adherence to HAART is that usually one has to rely on self-reported m...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/10872910260351267
更新日期:2002-10-01 00:00:00
abstract::We sought to determine the consequences of stopping highly active antiretroviral therapy (HAART) in a group of 41 HIV-infected individuals with undetectable HIV viral loads and CD4+ counts greater than 500 cells per microliter for 6 months or more. Clinical and laboratory parameters were monitored, as was the time to ...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2005.19.429
更新日期:2005-07-01 00:00:00
abstract::HIV-seropositive, active injection-drug users (IDUs), compared with other HIV populations, continue to have low rates of highly active antiretroviral therapy (HAART) use, contributing to disparities in their HIV health outcomes. We sought to identify individual-level, interpersonal, and structural factors associated w...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2009.0240
更新日期:2010-07-01 00:00:00
abstract::Increased lopinavir (LPV) exposure obtained in vivo through combination with low-dose ritonavir may overcome a certain grade of resistance but not all. We sought to analyze LPV variability and possible risk factors. LPV trough plasma concentrations were determined by high-performance liquid chromatography after 1, 4, ...
journal_title:AIDS patient care and STDs
pub_type: 临床试验,杂志文章
doi:10.1089/apc.2004.18.629
更新日期:2004-11-01 00:00:00
abstract::We used a standardized screening tool to examine frequency of depression and its relation to antiretroviral medication adherence among HIV-infected persons on highly active antiretroviral therapy (HAART) in the Study to Understand the Natural History of HIV/AIDS in the Era of Effective Therapy (SUN Study). This is a p...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章,多中心研究
doi:10.1089/apc.2012.0132
更新日期:2012-12-01 00:00:00
abstract::Although many methods for assessing adherence have been developed, most are not feasible for busy clinical settings. Using patients from the Adherence and Efficacy of Protease inhibitor Therapy (ADEPT) study (1998-2000), we systematically evaluated the relationship between psychosocial, environmental, clinical, and ot...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2006.20.760
更新日期:2006-11-01 00:00:00
abstract::HIV-seropositive blacks, Hispanics, women of all ethnicities, and injection drug users (IDUs) have low rates of clinical trial participation. The opinions of research nurses and study coordinators as potential facilitators and barriers to access to clinical trials may contribute to this disparity. Study coordinators a...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2006.0173
更新日期:2007-08-01 00:00:00
abstract::This study compared a multiple method measurement model of highly active antiretroviral therapy (HAART) adherence with single-method models to determine optimal validity in predicting HIV viral load. Repeated measures of antiretroviral adherence were collected over a 15-month period using three different measurement m...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章,随机对照试验
doi:10.1089/apc.2006.20.701
更新日期:2006-10-01 00:00:00
abstract::The purpose of this study was to evaluate the relationship between the coping self-efficacy (CSE) scale and adherence to HIV medication in men and women enrolled in a large HIV treatment program in Kenya. Data were collected from a sample of 354 volunteers attending Nazareth Hospital's nine satellite clinics located i...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2011.0125
更新日期:2011-09-01 00:00:00
abstract::Kaposi's sarcoma of the breast is extremely rare. We report a case of a patient with AIDS presenting with Kaposi's sarcoma localized to the breast and review another published case of a patient with AIDS and disseminated cutaneous Kaposi's sarcoma with breast involvement. Although rare, the diagnosis should be conside...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/108729100318019
更新日期:2000-02-01 00:00:00
abstract::The rate of HIV seroprevalence in Nigeria is troublesome because it is one of the highest prevalence rates worldwide. As in most developing countries, vertical transmission from mother to child accounts for most of the HIV infections in Nigerian children. The purpose of this study was to determine the awareness, attit...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2006.0065
更新日期:2007-04-01 00:00:00
abstract::Linking and engaging HIV-positive patients in care is the key bridging step to glean the documented health and prevention advantages of antiretroviral therapy (ART). In China, HIV transmission among men who have sex with men (MSM) is surging, yet many HIV-positive MSM do not use HIV care services. We conducted a quali...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2015.0296
更新日期:2016-02-01 00:00:00
abstract::As the New York City HIV=AIDS epidemic began generalizing beyond traditionally high-risk groups in the early 1990s, AIDS Service Organizations (ASO) sought to increase access to medical care and broaden service offerings to incorporate the needs of low-income women and their families. Strategies to achieve entry into ...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2008.0056
更新日期:2009-01-01 00:00:00
abstract::Adolescents account for most undiagnosed HIV infections in the United States. Although the Centers for Disease Control and Prevention (CDC) recommends universal HIV screening for all patients ≥13 years, <10% of adolescents have been tested for HIV. To identify earlier opportunities for adolescent HIV prevention and di...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2020.0033
更新日期:2020-09-01 00:00:00
abstract::Health information technology (HIT) offers the potential to improve care for persons living with HIV. Provider satisfaction with HIT is essential to realize benefits, yet its evaluation presents challenges. An HIV-specific, electronic clinical management and reporting system was implemented in Louisiana's eight HIV cl...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2008.0053
更新日期:2009-02-01 00:00:00
abstract::Kaposi's sarcoma (KS) is the most common malignancy observed in patients with acquired immune deficiency syndrome (AIDS). Although KS involves the head and neck in AIDS patients, difficult airway due to KS in an AIDS patient has rarely been reported in the literature. We report a patient with AIDS and cutaneous KS who...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/108729101750279650
更新日期:2001-06-01 00:00:00
abstract::This exploratory study examined patient-provider communication dynamics regarding adherence to highly active antiretroviral therapy (HAART) and protective sexual behavior among people living with HIV/AIDS (PLWHA). We conducted 20 direct observations of routine consultations between PLWHA and care providers in two larg...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2006.20.637
更新日期:2006-09-01 00:00:00
abstract::The prevalence of smoking in HIV-infected subjects is high. As a smoking cessation aid, varenicline (Champix(®), Pfizer, Saint-Laurent, QC, Canada or Chantix(®), Pfizer, Mission, KS) has not been previously evaluated in HIV-infected smokers. In this multicenter pilot open label study, varenicline 1.0 mg was used twice...
journal_title:AIDS patient care and STDs
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1089/apc.2011.0199
更新日期:2012-01-01 00:00:00
abstract::The introduction of protease inhibitors (PIs) and highly active antiretroviral therapy in the mid-1990s dramatically altered the treatment of HIV infection, enabling suppression of viral replication to undetectable levels and preventing disease progression. Most PIs present a strong barrier against viral resistance; t...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.2007.0099
更新日期:2008-04-01 00:00:00
abstract::Viral folliculitis is an infrequently reported entity. We describe two patients with viral folliculitides, including a case of herpetic sycosis caused by herpes simplex (HSV) and a case of herpes zoster (HZ) without blisters. Clinicians should consider viral etiologies in the differential diagnosis of superficial infe...
journal_title:AIDS patient care and STDs
pub_type: 杂志文章
doi:10.1089/apc.1999.13.513
更新日期:1999-09-01 00:00:00