Abstract:
:Exercise stress testing is a well-established method for the diagnostic, prognostic, and functional assessment of patients with known or suspected CAD. A variety of alternative tests have been described in patients unable to perform leg exercise. Atrial pacing and dipyridamole imaging have been evaluated most extensively, and results compare favorably with those of exercise testing for diagnosing the presence of CAD. Both tests may be used to assess prognosis after myocardial infarction, and dipyridamole imaging may be useful in patients undergoing preoperative evaluation. The use of the cold pressor test and isometric handgrip exercise have also been described. However, the value of both tests is limited by a relatively low sensitivity for detecting the presence of CAD. Other testing modalities--arm ergometry, intravenous infusion of beta-adrenergic agonists, and transthoracic pacing--show promise but require further assessment to confirm their value.
journal_name
Am Heart Jjournal_title
American heart journalauthors
Stratmann HG,Kennedy HLdoi
10.1016/0002-8703(89)90417-1subject
Has Abstractpub_date
1989-06-01 00:00:00pages
1344-65issue
6eissn
0002-8703issn
1097-6744pii
0002-8703(89)90417-1journal_volume
117pub_type
杂志文章,评审abstract:BACKGROUND:Lipid lowering through statin therapy significantly reduces the risk of cardiovascular events. The ENHANCE study is an international 2-year, randomized, double-blind, controlled trial designed to test the hypothesis that treatment of hypercholesterolemia by use of 2 complementary agents, ezetimibe (a specifi...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2004.06.024
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:Transradial approach (TRA) for cardiac catheterizations and interventions improves clinical outcomes compared with transfemoral access, and its use is increasing worldwide. However, there are limited data on successive use of same artery for repeat procedures. METHODS:Between May 2010 and May 2011, all cons...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2012.10.016
更新日期:2013-03-01 00:00:00
abstract::Three cases of rupture of the interventricular septum occurring coincident with acute inferior myocardial infarction are reported and the relevant literature is reviewed. One patient under-went successful surgical repair and, in addition, had an aneurysmectomy. Clues and pitfalls in diagnosis as well as the possible c...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(76)80407-3
更新日期:1976-07-01 00:00:00
abstract:BACKGROUND:The magnitude of benefit of cardiac resynchronization therapy (CRT) varies significantly among its recipients; approximately 30% of CRT patients do not report clinical improvement. Optimization of CRT pacing parameters can further improve cardiac function, both acutely and chronically. Echocardiographic opti...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2012.02.007
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:Sexuality is an important factor influencing quality of life that may be altered for patients with coronary disease. Little is known about the extent to which patients want their cardiologists to counsel them about sexuality. PURPOSE:Our study evaluated the extent to which patients with known coronary disea...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2002.124053
更新日期:2002-08-01 00:00:00
abstract::Recent developments have provided a unique opportunity for the organization of regional ST-elevation myocardial infarction (STEMI) receiving center (SRC) networks. Because cumulative evidence has demonstrated that rapid primary percutaneous coronary intervention (PCI) is the most effective reperfusion strategy for acu...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/j.ahj.2006.06.001
更新日期:2006-10-01 00:00:00
abstract::The effectiveness of postextrasystolic potentiation (PESP) was assessed to detect residual function of the left ventricle in seven patients with idiopathic dilated cardiomyopathy (IDC). The postextrasystolic changes in the aortic pressure pulse, global left ventricular function, and quantitative regional left ventricu...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(87)90661-2
更新日期:1987-06-01 00:00:00
abstract::The medical records of 254 patients with atrial fibrillation were reviewed to determine the incidence of embolic events in relation to type of cardiovascular disease, duration of atrial fibrillation, and use of anticoagulants. During a total follow-up of 833 patient-years in atrial fibrillation, there were 32 instance...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(86)90318-2
更新日期:1986-11-01 00:00:00
abstract::Fingolimod, a sphingosine-1-phosphate receptor (S1PR) modulator, was the first oral disease-modifying therapy approved for relapsing forms of multiple sclerosis; it reduces autoreactive lymphocytes' egress from lymphoid tissues by down-regulating S1PRs. Sphingosine-1-phosphate signaling is implicated in a range of phy...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/j.ahj.2014.06.028
更新日期:2014-11-01 00:00:00
abstract::Although many patients with coronary artery disease (CAD) have a positive exercise test without pain, the frequency and significance of this "silent" ischemia is unclear. Therefore, we studied 122 consecutive clinically stable patients with angiographically defined CAD (greater than 75 per cent luminal stenosis) and a...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(78)90234-x
更新日期:1978-04-01 00:00:00
abstract:AIM:The EARISA Registry was designed to describe diagnostic and therapeutic resources used in Italian cardiology centers for patients with the epidemiologically most relevant cardiac diseases. This article focuses on patients with unstable angina; characteristics associated with invasive procedures were specifically an...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2000.107997
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:Previous studies have demonstrated that the adenosine monophosphate deaminase 1 (AMPD1) C34T polymorphism may be associated with survival in cardiac populations with a protective effect of the T allele. However, these studies included limited number of patients with few cardiovascular events. METHODS:We pro...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2006.04.003
更新日期:2006-10-01 00:00:00
abstract:AIMS:Paclitaxel-eluting stents (PESs) have been shown to inhibit neointimal hyperplasia after percutaneous coronary intervention. Coroflex Please (B Braun, Melsungen, Germany) is a newly developed PES. We compared the clinical and angiographic efficacy of Coroflex Please with Taxus Liberte (Boston Scientific, Natick, M...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2013.02.009
更新日期:2013-05-01 00:00:00
abstract::Left ventricular ejection fraction and regional wall motion were assessed by multigated equilibrium radionuclide ventriculography within 24 hours of onset of first acute transmural myocardial infarction (MI) in 32 patients. Abnormal left ventricular wall motion was noted in all 16 patients with anterior infarction and...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(83)90644-0
更新日期:1983-11-01 00:00:00
abstract:OBJECTIVE:Implantation of drug-eluting stents has emerged as the predominant percutaneous revascularization strategy in diabetic patients, despite limited outcomes data. Accordingly, our aim was to conduct a meta-analysis to assess the benefit and safety profile of drug-eluting stents in diabetic patients. METHODS:We ...
journal_title:American heart journal
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ahj.2007.11.017
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Peak exercise oxygen consumption (peak VO2) is an important discriminator of survival in patients with systolic heart failure and is used to select ambulatory patients for transplantation. The major trials assessing the relationship between peak VO2 and survival have used a variety of low-level exercise prot...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1067/mhj.2001.117508
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:All patients who present to an emergency department (ED) are triaged. The ED triage score may determine when patients are seen by a physician. Half of patients with acute myocardial infarction (AMI) were given a low priority score in Ontario in 2000/2001. We assessed the appropriateness of ED triage and its ...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2011.05.015
更新日期:2011-09-01 00:00:00
abstract:OBJECTIVES:We sought to determine the relationship of adverse diastolic remodeling (ie, worsening diastolic or persistent restrictive filling) with infarct scar characteristics, and to evaluate its prognostic value after ST-segment elevation myocardial infarction (STEMI). BACKGROUND:Severe diastolic dysfunction (restr...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2016.05.020
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:In the setting of ST-segment elevation myocardial infarction, timely restoration of normal blood flow is associated with improved myocardial salvage and survival. Despite improvements in door-to-needle and door-to-balloon times, there remains an unmet need with respect to improved symptom-to-door times. A pr...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.ahj.2014.05.010
更新日期:2014-10-01 00:00:00
abstract::1. A 4-year-old boy with the congenital partial defect of the left pericardium who presented with myocardial infarction, died of incarceration of the left ventricle. 2. This is the fourth reported case of death from this anomaly in the world. 3. Because this anomaly occasionally causes sudden death, it is important to...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(80)90068-x
更新日期:1980-12-01 00:00:00
abstract:BACKGROUND:Current guidelines (American College of Cardiology/American Heart Association) for percutaneous coronary intervention (PCI) limit the performance of elective cases to hospitals with the capability for cardiac surgery. The number of hospitals in the United States with this capability is limited, which restric...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2004.03.040
更新日期:2004-10-01 00:00:00
abstract:BACKGROUND:Intracranial hemorrhage is an uncommon but very dangerous complication in patients receiving thrombolytic therapy for acute myocardial infarction. Neurosurgical evacuation is often an available treatment option. However, the association between neurosurgical evacuation and clinical outcomes in these patients...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0002-8703(99)70152-3
更新日期:1999-09-01 00:00:00
abstract:BACKGROUND:We aimed to characterize the clinical and pathologic findings of aortic dissection (AD) over a nearly 60-year period. METHODS:The Jesse E. Edwards Registry of Cardiovascular Disease database was queried for cardiac specimens from autopsies with AD as a diagnosis and compared 2 cohorts: early (1956-1992) and...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2018.11.006
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Parasympathetic dysautonomia is an established feature of advanced Chagas cardiomyopathy. However, in the absence of cardiac involvement, the presence of vagal dysfunction remains controversial. In a cross-sectional study, we compared patients with Chagas disease without cardiac involvement and healthy indiv...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2001.111406
更新日期:2001-02-01 00:00:00
abstract::Patients with impaired glucose tolerance (IGT) have increased risk for developing type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). Lifestyle modification and medication can prevent or delay progression to diabetes (PD), but whether such interventions also reduce the risk of CVD has not been rigorously...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2008.05.017
更新日期:2008-10-01 00:00:00
abstract::Three patients with subpulmonic ventricular septal defect and pulmonary valve fluttering by echocardiography are presented. The echographic changes appear identical to that reported with infundibular pulmonic stenosis and the mechanism causing this fluttering is probably similar. ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(77)80336-0
更新日期:1977-07-01 00:00:00
abstract::Dobutamine (and dopamine) are potent positive inotropic drugs which are frequently given to treat decompensated congestive heart failure. This study reports on the use of ambulatory dobutamine (and dopamine) infusions in 21 outpatients with advanced congestive heart failure. Each patient was initially hospitalized, an...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(87)90757-5
更新日期:1987-09-01 00:00:00
abstract::Saphenous vein graft (SVG) failure is a common finding in patients following coronary artery bypass graft (CABG) surgery. In the literature SVG failure rates have been reported from 25 to over 50% within 10 years. Although common, it remains unclear to what extent SVG failure affects clinical outcome, due to differenc...
journal_title:American heart journal
pub_type: 社论
doi:10.1016/j.ahj.2013.01.019
更新日期:2013-05-01 00:00:00
abstract::Hemodynamic studies were performed in 27 patients at a mean interval of 40.3 (range 24 to 59) months following mitral valve replacement with pericardial xenografts. Six patients had sequential studies, one before operation and two separate investigations at mean intervals of 11.2 and 42.8 months following valve replac...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(78)90301-0
更新日期:1978-05-01 00:00:00
abstract::Because of its unique ability to demonstrate the metabolic consequences of myocardial ischemia, positron emission tomography (PET) is extremely valuable in assessing myocardial viability. PET imaging can identify the myocardial segments that are likely to improve after revascularization and may be more sensitive and s...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/0002-8703(91)90803-p
更新日期:1991-07-01 00:00:00