Abstract:
AIM:To explore possible correlations between tumour apparent diffusion coefficient (ADC), morphological tumour volume, and clinical and histological characteristics in endometrial carcinomas and to evaluate interobserver agreement for preoperative staging by MRI and for ADC measurements. MATERIALS AND METHODS:Preoperative conventional MRI including diffusion-weighted imaging (DWI) was performed in 105 endometrial carcinoma patients. Three radiologists independently reviewed the images for the presence of deep myometrial invasion, cervical stromal invasion, and lymph node metastases, and measured tumour ADC in regions of interest (ROIs). ADC values were analysed in relation to histomorphological characteristics and tumour volume. Kappa coefficients (κ) and intraclass correlation coefficients (ICC) for interobserver agreement for MRI staging results and ADC measurements, respectively, were calculated, and receiver operating characteristic (ROC) curves for identification of deep of myometrial invasion were generated. RESULTS:Mean tumour ADC was significantly lower in tumours with deep myometrial invasion (ADC = 0.75 × 10(-3) mm(2)/s) compared to tumours with superficial or no myometrial invasion (ADC = 0.85 × 10(-3) mm(2)/s; p < 0.001). ADC was negatively correlated to tumour size (p = 0.007). The interobserver agreement was fair (κ = 0.32) for depth of myometrial invasion, good for cervical stromal invasion (κ = 0.66), and moderate for lymph node metastases (κ = 0.54), and the interobserver variability for ADC value measurements was low (ICC = 0.60). CONCLUSION:Tumour ADC measurements may in the future provide an adjunct tool, aiding in the preoperative identification of high-risk patients with deep myometrial infiltration.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Husby JA,Salvesen ØO,Magnussen IJ,Trovik J,Bjørge L,Salvesen HB,Haldorsen ISdoi
10.1016/j.crad.2014.12.016subject
Has Abstractpub_date
2015-05-01 00:00:00pages
487-94issue
5eissn
0009-9260issn
1365-229Xpii
S0009-9260(15)00020-3journal_volume
70pub_type
杂志文章abstract::Computed tomography (CT) studies of the brain are one of the most frequent examinations interpreted by radiologists out of hours. Apparently normal appearances in patients with significant neurological morbidity can be perplexing. As the contents of the cranium are normally remarkably symmetrical on axial CT, disease ...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2008.08.012
更新日期:2009-03-01 00:00:00
abstract::We have retrospectively assessed the computed tomography (CT) findings in 92 patients suffering severe blunt abdominal trauma. Surgical findings and clinical follow-up were correlated with the CT findings. In nine patients CT was first used after emergency surgery and provided baseline data which was useful for furthe...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80373-3
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abstract::The relationship of microcalcification to lobulo-ductal dysplasia and non-invasive carcinoma was studied in 20 women with in situ carcinoma of the breast. All had microcalcification on the mammogram and in half there was also mammographic evidence of disruption of the breast structure. Three-quarters of the women pres...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(78)80109-3
更新日期:1978-07-01 00:00:00
abstract::Mycobacterial infection is re-emerging as a major health care concern. Although Mycobacterium tuberculosis(MTB) is still the most important pathogen, atypical mycobacterium (AMB) infections are becoming increasingly common. We present a pictorial review of the imaging features of these infections in the chest, abdomen...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1053/crad.2001.0755
更新日期:2001-07-01 00:00:00
abstract::Thirty-seven instant (unprepared) barium enemas in 30 patients with proven Crohn's colitis were reviewed. Plain films in 28 indicated that confluence or discontinuity of the colitis did not substantially alter the pattern of faecal residue. In only one patient was residue found overlying active mucosal disease. Aphtho...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81454-0
更新日期:1993-05-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/s0009-9260(03)00188-0
更新日期:2003-08-01 00:00:00
abstract:AIM:To prospectively analyse the occurrence of right coronary artery (RCA) artefact and assess its relationship with patient heart rate (HR) and HR variability (HRV) in order to determine the most appropriate parameters for high-pitch cardiovascular computed tomography (CT) acquisition, minimize the likelihood of artef...
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pub_type: 杂志文章
doi:10.1016/j.crad.2014.01.013
更新日期:2014-07-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(80)80095-x
更新日期:1980-01-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2020.03.028
更新日期:2020-06-01 00:00:00
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doi:10.1016/j.crad.2016.10.020
更新日期:2017-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/s0009-9260(83)80148-2
更新日期:1983-09-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2017.11.025
更新日期:2018-05-01 00:00:00
abstract::The accuracy of high field, endorectal MRI in the staging of localized prostate cancer has been the focus of many previous reports. We present our findings with a mid-field magnet. Twenty-two patients with clinically localized prostate cancer were prospectively staged with endorectal MRI using a 0.5 T magnet. All pati...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(96)80133-4
更新日期:1996-08-01 00:00:00
abstract::Two patients with benign chondrolipomatous tumours of the breast were subjected to mammography. In one case this was as part of the investigation of a breast lump detected clinically, while in the other the lesion was detected during routine follow-up of a woman with long-standing cystic hyperplasia. The mammographic ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(88)80560-9
更新日期:1988-05-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章,多中心研究
doi:10.1016/s0009-9260(03)00058-8
更新日期:2003-05-01 00:00:00
abstract::We report a case of a patient with sickle cell disease who presented with mesenteric nodes and pulmonary TB and who subsequently relapsed on triple therapy and presented with disseminated tuberculous osteomyelitis and cervical lymphadenopathy. We emphasize the difficulty of establishing the diagnosis at all stages of ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80648-8
更新日期:1992-03-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2007.10.014
更新日期:2008-05-01 00:00:00
abstract:AIM:To assess the effect of the presence and locality of symptomatic lower-limb deep vein thrombosis (DVT) on mortality and morbidity following contrast venography (CV), the reference standard for diagnosing below-knee DVT, with a view to determining the prevalence of recurrent episodes of DVT and post-thrombotic syndr...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2015.12.014
更新日期:2016-04-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
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更新日期:2010-12-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1053/crad.2002.1116
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journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2012.07.016
更新日期:2013-04-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2007.09.014
更新日期:2008-05-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)82906-x
更新日期:1994-01-01 00:00:00
abstract:AIM:To investigate the imaging features of chondrosarcoma of the temporomandibular joint (TMJ) and review the literature. MATERIALS AND METHODS:Computed tomography (CT), magnetic resonance imaging (MRI), and integrated positron-emission tomography (PET)/CT images of nine patients with histopathologically confirmed cho...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2020.07.016
更新日期:2020-11-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80093-5
更新日期:1992-05-01 00:00:00
abstract::Left ventriculography with selective coronary angiography was performed on 13 patients with acute myocardial infarcts complicated by cardiogenic shock of left ventricular failure and hypotension. Twelve patients (92-3%) tolerated the procedure well. Irreversible ventricular fibrillation resulting in death occurred in ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(77)80105-0
更新日期:1977-03-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2005.09.002
更新日期:2006-01-01 00:00:00
abstract:AIM:To examine whether Positron Emission Tomography Response Criteria in Solid Tumours (PERCIST) is useful to predict tumour response and prognosis of patients with oesophageal cancer who received neoadjuvant chemoradiotherapy (NACRT) followed by surgery. MATERIALS AND METHODS:This multicentre retrospective study incl...
journal_title:Clinical radiology
pub_type: 杂志文章,多中心研究
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更新日期:2020-01-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80872-4
更新日期:1991-09-01 00:00:00
abstract::Since 1971, 82 patients with advanced carcinoma of the cervix have been included in a randomised clinical trial in association with the Working Party on Radiotherapy and Hyperbaric Oxygen of the Medical Research Council. External irradiation was given in 10 fractions by an unconventional schedule, either in air or HBO...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1979-07-01 00:00:00