Radiological features and metastatic patterns of thymic neuroendocrine tumours.

Abstract:

AIM:To investigate the clinical and image features of thymic neuroendocrine tumours (NETs), and characterise the radiological patterns of recurrence and metastasis on serial imaging studies. MATERIALS AND METHODS:The study included 14 patients (11 males) with a histopathological diagnosis of thymic NETs (one typical carcinoid, eight atypical carcinoid, and five large cell neuroendocrine carcinoma). Preoperative images were assessed for features of primary tumours. Follow-up imaging studies were evaluated for the patterns of metastasis or recurrence. RESULTS:Underlying endocrine or autoimmune disorders were present in four patients (29%), including multiple endocrine neoplasia (MEN) type 1 (n=3) and autoimmune thyroiditis (n=1). On preoperative imaging, the primary tumours were commonly lobulate and heterogeneous, infiltrated the surrounding fat, and showed ≥50% abutment of the mediastinal structures, with the mean longest diameter of 14 cm (range: 4.1-28 cm). No significant differences of preoperative imaging features were noted among histopathological subtypes. Metastasis or recurrence was noted in 11 of the 14 patients (79%). Ten patients developed intrathoracic metastasis or recurrence, involving thoracic lymph nodes (n=7), pleura (n=4), lung (n=4), pericardium (n=4), and local recurrence in the postoperative mediastinum (n=3). Eight of the 11 patients also had extra-thoracic metastasis, involving bone (n=6), abdominal lymph nodes (n=4), liver, pancreas, kidney, adrenal gland, spleen and brain (n=1 for each site). CONCLUSIONS:Thymic NETs presented as a large, lobulate, heterogeneous mass with an infiltrative nature. Metastasis and recurrence were frequent, most commonly involving thoracic lymph nodes, while extra-thoracic metastasis to bones and abdominal lymph nodes were also noted.

journal_name

Clin Radiol

journal_title

Clinical radiology

authors

Araki T,Sholl LM,Hatabu H,Nishino M

doi

10.1016/j.crad.2017.11.025

subject

Has Abstract

pub_date

2018-05-01 00:00:00

pages

479-484

issue

5

eissn

0009-9260

issn

1365-229X

pii

S0009-9260(17)30564-0

journal_volume

73

pub_type

杂志文章
  • Bone marrow changes on MRI in children with acute lymphoblastic leukaemia 5 years after treatment.

    abstract::T1-weighted magnetic resonance imaging (MRI) of the lower extremities was performed 5 years after the cessation of therapy on 25 children treated for acute lymphoblastic leukaemia (ALL). Signal intensity pathologies considered to be related with the leukaemia itself or the treatment of ALL were found in nine of 25 chi...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(98)80060-3

    authors: Ojala AE,Pääkkö E,Lanning FP,Harila-Saari AH,Lanning BM

    更新日期:1998-02-01 00:00:00

  • The chest film findings in 'Q' fever--a series of 35 cases.

    abstract::Thirty-five cases of 'Q' fever have been admitted and confirmed serologically over the past 20 years. Thirty-two of these cases had chest films on admission, and lung changes were present in 87%. The lung changes were: 1. Multiple round segmental consolidations, 5--10 cm in diameter, of ground glass density and usuall...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(78)80092-0

    authors: Millar JK

    更新日期:1978-07-01 00:00:00

  • Lung nodules are reliably detectable on ultra-low-dose CT utilising model-based iterative reconstruction with radiation equivalent to plain radiography.

    abstract:AIM:To determine if ultra-low-dose (ULD) computed tomography (CT) utilising model-based iterative reconstruction (MBIR) with radiation equivalent to plain radiography allows the detection of lung nodules. MATERIALS AND METHODS:Ninety-nine individuals undergoing surveillance of solid pulmonary nodules undertook a low-d...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2019.02.001

    authors: Miller AR,Jackson D,Hui C,Deshpande S,Kuo E,Hamilton GS,Lau KK

    更新日期:2019-05-01 00:00:00

  • The distended neonate.

    abstract::A prospective study, followed by a retrospective audit, was made of the radiographs and clinical features of 225 consecutive neonates with abdominal distension presenting during a period of 4 years. More than one major cause for the distension was found in a third of cases. Excluding cases of ano-rectal atresia, diagn...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(83)80217-7

    authors: Carty H,Brereton RJ

    更新日期:1983-07-01 00:00:00

  • HRCT findings of collagen vascular disease-related interstitial pneumonia (CVD-IP): a comparative study among individual underlying diseases.

    abstract:AIM:To identify characteristic high-resolution computed tomography (CT) findings for individual collagen vascular disease (CVD)-related interstitial pneumonias (IPs). MATERIALS AND METHODS:The HRCT findings of 187 patients with CVD, including 55 patients with rheumatoid arthritis (RA), 50 with systemic sclerosis (SSc)...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2018.04.017

    authors: Tanaka N,Kunihiro Y,Kubo M,Kawano R,Oishi K,Ueda K,Gondo T

    更新日期:2018-09-01 00:00:00

  • Standard of the descending (basal) pulmonary artery in children from the routine chest radiograph.

    abstract::The right and left basal artery have been measured in serial radiographs taken annually for 3 years or more, in 48 boys and 45 girls, all clinically normal. Centiles were constructed from 5 to 15 year old children. A study of the gain in size revealed a growth spurt during the pubertal period corresponding to that see...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(76)80130-4

    authors: Simon G,Rona R

    更新日期:1976-10-01 00:00:00

  • Pre-operative imaging of esthesioneuroblastoma.

    abstract::The pre-operative images of three patients with biopsy proven esthesioneuroblastoma are presented. The role of computed tomography (CT) and magnetic resonance imaging (MRI) in the pre-operative determination of tumour extent is discussed. ...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(05)83295-7

    authors: Eustace S,Suojanen J,Buff B,McEniff N,Januario J,Norris C

    更新日期:1995-09-01 00:00:00

  • Scaphoid and pronator fat stripes are unreliable soft tissue signs in the detection of radiographically occult fractures.

    abstract:AIM:To determine the clinical value of scaphoid and pronator fat stripes in identifying occult underlying scaphoid and distal radius fractures, respectively. MATERIALS AND METHODS:In our department, all patients with clinically suspected scaphoid fractures and normal scaphoid series of radiographs undergo magnetic res...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(03)00230-7

    authors: Annamalai G,Raby N

    更新日期:2003-10-01 00:00:00

  • Radiology is valuable to general practitioners; but who pays?

    abstract::This study evaluated an open access general practitioner radiological service. Questionnaires were completed in 216 out of 250 cases both before and after radiological examination. Chests and specials (bariums, intravenous urography, ultrasound) were most often of diagnostic value when confirming normality, while othe...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(89)80088-1

    authors: Stoddart PG,Holl SG

    更新日期:1989-03-01 00:00:00

  • CT-guided percutaneous core-needle biopsy of pancreatic masses: comparison of the standard mesenteric/retroperitoneal versus the trans-organ approaches.

    abstract:AIM:To compare the safety and efficacy of percutaneous computed tomography (CT)-guided core-needle biopsy (CNB) of pancreatic masses traversing the gastrointestinal tract or solid viscera versus trans-mesenteric and retroperitoneal approaches. MATERIALS AND METHODS:CT-guided CNB of pancreatic lesions performed between...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2016.02.021

    authors: Hsu MY,Pan KT,Chen CM,Lui KW,Chu SY,Lin YY,Hung CF,Huang YT,Tseng JH

    更新日期:2016-06-01 00:00:00

  • False-negative MRI breast screening in high-risk women.

    abstract:AIM:To determine the frequency of and reasons for false-negative breast magnetic resonance imaging (MRI) examinations in high-risk women undergoing annual screening. MATERIALS AND METHODS:The family history clinic database was interrogated and women at high risk of breast cancer who had undergone screening MRI and bee...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2016.10.020

    authors: Maxwell AJ,Lim YY,Hurley E,Evans DG,Howell A,Gadde S

    更新日期:2017-03-01 00:00:00

  • 16-Detector multislice CT in the detection of stress fractures: a comparison with skeletal scintigraphy.

    abstract:AIMS:To test the hypothesis that the improved resolution afforded by 16-detector computed tomography (CT) would translate to better stress fracture detection when compared with skeletal scintigraphy. MATERIALS AND METHODS:Thirty-three cases of suspected stress fractures in 26 patients were investigated using skeletal ...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2005.05.014

    authors: Groves AM,Cheow HK,Balan KK,Housden BA,Bearcroft PW,Dixon AK

    更新日期:2005-10-01 00:00:00

  • Multislice computed tomography cardiac imaging: current status.

    abstract::Non-invasive CT coronary artery imaging has previously had little relevance to most UK radiologists due to the limited availability of electron beam CT scanners. Major advances in CT technology have promoted new applications for helical CT, which include cardiac imaging. Widespread installation of 'multislice' helical...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审

    doi:10.1053/crad.2002.1072

    authors: Morgan-Hughes GJ,Marshall AJ,Roobottom CA

    更新日期:2002-10-01 00:00:00

  • Collateral circulation via the circle of Willis in patients with carotid artery steno-occlusive disease: evaluation on 3-T 4D MRA using arterial spin labelling.

    abstract:AIM:To evaluate whether 3-T four-dimensional (4D) arterial spin-labelling (ASL) -based magnetic resonance angiography (MRA) is useful for assessing the collateral circulation via the circle of Willis in patients with carotid artery steno-occlusive disease. MATERIALS AND METHODS:Institutional review board approval and ...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2015.05.002

    authors: Iryo Y,Hirai T,Nakamura M,Inoue Y,Watanabe M,Ando Y,Azuma M,Nishimura S,Shigematsu Y,Kitajima M,Yamashita Y

    更新日期:2015-09-01 00:00:00

  • Large subarticular cysts (geodes) adjacent to the knee-joint in rheumatoid arthritis.

    abstract::Two patients with rheumatoid arthritis are described, who developed very large bone cysts or geodes adjacent to the knee-joint. The existence of cysts adjacent to joints involved by rheumatoid arthritis is well recognised, but the occurrence of very large cysts is unusual and may present diagnostic difficulties. Possi...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(75)80118-8

    authors: Carter AR,Liyanage SP

    更新日期:1975-10-01 00:00:00

  • Duplex ultrasound of the abdominal aorta--a neglected tool in aortic dissection.

    abstract::The use of duplex ultrasound for the diagnosis and assessment of abdominal aortic dissection and visceral arterial involvement is discussed. Ultrasound is simple and non-invasive and may be superior to aortography in diagnosis; it should be performed after ultrasound assessment of the aortic root. It also provides an ...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(05)82147-6

    authors: Thomas EA,Dubbins PA

    更新日期:1990-11-01 00:00:00

  • Systematic tutorials in radiology for clinical medical students.

    abstract::The aims and objectives of radiological teaching to clinical medical students at one teaching hospital are defined and the methods of achieving these using systematic small group tutorials are described. The objectives of the course are to enable a newly qualified doctor to request radiological investigations sensibly...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(84)80125-7

    authors: Jeans WD,Davies ER

    更新日期:1984-05-01 00:00:00

  • CT herniography in the diagnosis of occult groin hernias.

    abstract:AIM:To evaluate the role of computed tomography (CT) after herniography in the diagnosis and management of primary and recurrent groin hernias not detectable on clinical examination. MATERIAL AND METHODS:Fifty-one patients underwent CT post-herniography over a 6-year period for suspected primary or recurrent inguinal ...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2004.02.013

    authors: Markos V,Brown EF

    更新日期:2005-02-01 00:00:00

  • The use of ultrasound for the assessment of enthesitis in patients with spondyloarthritis.

    abstract::Seronegative spondyloarthritis (SpA) represents a group of diseases that share certain genetic, clinical, and radiographic features. Enthesitis, inflammation at the site of tendon insertion into the bone, involving both the axial and the peripheral joints, is an important sign of SpA. Clinical diagnosis of enthesitis,...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.crad.2012.07.018

    authors: Eder L,Barzilai M,Peled N,Gladman DD,Zisman D

    更新日期:2013-03-01 00:00:00

  • Imaging of children with urinary tract infection: a tailored approach.

    abstract::We reviewed the initial imaging studies of 283 children with urinary tract infection in order to decide on the most effective approach. A voiding cystogram was performed in all, complemented by either urography (147 patients), ultrasonography (65), or both (71 patients). In the latter group there was good correlation ...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(89)80031-5

    authors: Ben-Ami T,Rozin M,Hertz M

    更新日期:1989-01-01 00:00:00

  • With advances in medical imaging can the radiologist reliably diagnose Wilms' tumours?

    abstract:AIM:To evaluate whether radiologists can accurately differentiate Wilms' tumours from other paediatric abdominal masses with renal involvement using modern imaging methods alone. METHODS:From February 1993 to June 1997, 23 patients presented to the Paediatric Oncology Service at The Royal Hospital for Sick Children, E...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(99)90563-9

    authors: Scott DJ,Wallace WH,Hendry GM

    更新日期:1999-05-01 00:00:00

  • Case report: obstructive jaundice secondary to an intussuscepting duodenal villous adenoma.

    abstract::Small intestinal tumours are rare, forming 1% of all gastrointestinal tumours; most occur in the duodenum. Villous adenomas form only a very small proportion of the duodenal tumours. They usually occur in the periampullary region and show a marked propensity for malignant change. The usual mode of presentation is with...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(05)80040-6

    authors: Vinnicombe S,Grundy A

    更新日期:1992-07-01 00:00:00

  • A retrospective validation of an imaging protocol for the management of solitary central cartilage tumours of the proximal humerus and around the knee.

    abstract:AIM:To validate an imaging protocol for the management of solitary central cartilage tumours (CCTs) of the proximal humerus and around the knee. MATERIALS AND METHODS:Over a 10-year period, 387 patients were identified with a CCT in the proximal humerus, distal femur, and proximal tibia, who were referred to a single ...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2019.08.017

    authors: Davies AM,Patel A,James SL,Botchu R

    更新日期:2019-12-01 00:00:00

  • The radiology of external carotid-internal carotid anastomosis.

    abstract::Surgical anastomosis between branches of the external and internal carotid arteries may be beneficial in selected cases of transient ischaemic attacks and reversible ischaemic neurological deficit. It is the responsibility of the radiologist, at the time of initial angiographic evaluation, to recognise patients who mi...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(79)80197-x

    authors: Cail WS,Morris JL

    更新日期:1979-09-01 00:00:00

  • Magnetic resonance imaging in osteomalacic insufficiency fractures of the pelvis.

    abstract:AIMS:To report the magnetic resonance imaging (MRI) findings of osteomalacic insufficiency fractures of the pelvis. MATERIALS AND METHODS:In all, 12 persons presenting with chronic pelvic pain and with a definitive diagnosis of osteomalacia (OM) were enrolled in this study. Radiological work-up included direct radiogr...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2004.04.021

    authors: Kanberoglu K,Kantarci F,Cebi D,Yilmaz MH,Kurugoglu S,Bilici A,Koyuncu H

    更新日期:2005-01-01 00:00:00

  • Computed tomography in the assessment of response to limb compression in unilateral lymphoedema.

    abstract::In this prospective study computed tomography (CT) was used to monitor the response of compression therapy in 27 patients with chronic unilateral lymphoedema over a 12 week period. Computed tomography examination of abnormal and normal limbs (proximal and distal portions) was performed in the first, third and 12th wee...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/s0009-9260(05)83188-5

    authors: Collins CD,Mortimer PS,D'Ettorre H,A'Hern RP,Moskovic EC

    更新日期:1995-08-01 00:00:00

  • Trans-organ versus trans-mesenteric computed tomography-guided percutaneous fine-needle aspiration biopsy of pancreatic masses: feasibility and safety.

    abstract:AIM:To evaluate the safety and efficacy of computed tomography (CT)-guided percutaneous fine-needle aspiration biopsy (FNAB) of pancreatic masses that traverses the gastrointestinal tract or solid viscera. MATERIALS AND METHODS:From January 2002 to December 2012, 144 patients underwent 165 CT-guided biopsies of pancre...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2014.05.111

    authors: Hsu MY,Pan KT,Chen CM,Lui KW,Chu SY,Hung CF,Huang YT,Tseng JH

    更新日期:2014-10-01 00:00:00

  • Using magnetic resonance diffusion tensor imaging to evaluate renal function changes in diabetic patients with early-stage chronic kidney disease.

    abstract:AIM:To investigate the clinical value of diffusion tensor imaging (DTI) in assessing renal function changes in diabetic patients with early-stage chronic kidney disease (CKD), and the relationship of DTI parameters with estimated glomerular filtration rate (eGFR) and urinary biomarkers. MATERIALS AND METHODS:Thirty-si...

    journal_title:Clinical radiology

    pub_type: 杂志文章

    doi:10.1016/j.crad.2018.09.011

    authors: Ye XJ,Cui SH,Song JW,Liu K,Huang XY,Wang L,Zhou YJ,Yan ZH,Wang GB

    更新日期:2019-02-01 00:00:00

  • The transjugular intrahepatic portosystemic shunt (TIPS).

    abstract::The creation of an intrahepatic portosystemic shunt via a transjugular approach (TIPS) is an interventional radiological procedure used to treat the complications of portal hypertension. TIPS insertion is principally indicated to prevent or arrest variceal bleeding when medical or endoscopic treatments fail, and in th...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.crad.2008.09.017

    authors: Owen AR,Stanley AJ,Vijayananthan A,Moss JG

    更新日期:2009-07-01 00:00:00

  • Implementing lung cancer screening: the US experience.

    abstract::The reduced lung cancer mortality observed with low-dose computed tomography (LDCT) screening in the National Lung Screening Trial (NLST) has led to annual screening in the United States as a covered benefit by both private insurers and the federal health insurance programme, the Centers for Medicare and Medicaid Serv...

    journal_title:Clinical radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.crad.2016.12.003

    authors: Aberle DR

    更新日期:2017-05-01 00:00:00