Abstract:
AIM:To investigate the clinical and image features of thymic neuroendocrine tumours (NETs), and characterise the radiological patterns of recurrence and metastasis on serial imaging studies. MATERIALS AND METHODS:The study included 14 patients (11 males) with a histopathological diagnosis of thymic NETs (one typical carcinoid, eight atypical carcinoid, and five large cell neuroendocrine carcinoma). Preoperative images were assessed for features of primary tumours. Follow-up imaging studies were evaluated for the patterns of metastasis or recurrence. RESULTS:Underlying endocrine or autoimmune disorders were present in four patients (29%), including multiple endocrine neoplasia (MEN) type 1 (n=3) and autoimmune thyroiditis (n=1). On preoperative imaging, the primary tumours were commonly lobulate and heterogeneous, infiltrated the surrounding fat, and showed ≥50% abutment of the mediastinal structures, with the mean longest diameter of 14 cm (range: 4.1-28 cm). No significant differences of preoperative imaging features were noted among histopathological subtypes. Metastasis or recurrence was noted in 11 of the 14 patients (79%). Ten patients developed intrathoracic metastasis or recurrence, involving thoracic lymph nodes (n=7), pleura (n=4), lung (n=4), pericardium (n=4), and local recurrence in the postoperative mediastinum (n=3). Eight of the 11 patients also had extra-thoracic metastasis, involving bone (n=6), abdominal lymph nodes (n=4), liver, pancreas, kidney, adrenal gland, spleen and brain (n=1 for each site). CONCLUSIONS:Thymic NETs presented as a large, lobulate, heterogeneous mass with an infiltrative nature. Metastasis and recurrence were frequent, most commonly involving thoracic lymph nodes, while extra-thoracic metastasis to bones and abdominal lymph nodes were also noted.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Araki T,Sholl LM,Hatabu H,Nishino Mdoi
10.1016/j.crad.2017.11.025subject
Has Abstractpub_date
2018-05-01 00:00:00pages
479-484issue
5eissn
0009-9260issn
1365-229Xpii
S0009-9260(17)30564-0journal_volume
73pub_type
杂志文章abstract::T1-weighted magnetic resonance imaging (MRI) of the lower extremities was performed 5 years after the cessation of therapy on 25 children treated for acute lymphoblastic leukaemia (ALL). Signal intensity pathologies considered to be related with the leukaemia itself or the treatment of ALL were found in nine of 25 chi...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(98)80060-3
更新日期:1998-02-01 00:00:00
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doi:10.1016/s0009-9260(78)80092-0
更新日期:1978-07-01 00:00:00
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更新日期:2019-05-01 00:00:00
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journal_title:Clinical radiology
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doi:10.1016/s0009-9260(83)80217-7
更新日期:1983-07-01 00:00:00
abstract:AIM:To identify characteristic high-resolution computed tomography (CT) findings for individual collagen vascular disease (CVD)-related interstitial pneumonias (IPs). MATERIALS AND METHODS:The HRCT findings of 187 patients with CVD, including 55 patients with rheumatoid arthritis (RA), 50 with systemic sclerosis (SSc)...
journal_title:Clinical radiology
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doi:10.1016/j.crad.2018.04.017
更新日期:2018-09-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(76)80130-4
更新日期:1976-10-01 00:00:00
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journal_title:Clinical radiology
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doi:10.1016/s0009-9260(05)83295-7
更新日期:1995-09-01 00:00:00
abstract:AIM:To determine the clinical value of scaphoid and pronator fat stripes in identifying occult underlying scaphoid and distal radius fractures, respectively. MATERIALS AND METHODS:In our department, all patients with clinically suspected scaphoid fractures and normal scaphoid series of radiographs undergo magnetic res...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(03)00230-7
更新日期:2003-10-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(89)80088-1
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2016.02.021
更新日期:2016-06-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2016.10.020
更新日期:2017-03-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2005.05.014
更新日期:2005-10-01 00:00:00
abstract::Non-invasive CT coronary artery imaging has previously had little relevance to most UK radiologists due to the limited availability of electron beam CT scanners. Major advances in CT technology have promoted new applications for helical CT, which include cardiac imaging. Widespread installation of 'multislice' helical...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1053/crad.2002.1072
更新日期:2002-10-01 00:00:00
abstract:AIM:To evaluate whether 3-T four-dimensional (4D) arterial spin-labelling (ASL) -based magnetic resonance angiography (MRA) is useful for assessing the collateral circulation via the circle of Willis in patients with carotid artery steno-occlusive disease. MATERIALS AND METHODS:Institutional review board approval and ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2015.05.002
更新日期:2015-09-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(75)80118-8
更新日期:1975-10-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)82147-6
更新日期:1990-11-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(84)80125-7
更新日期:1984-05-01 00:00:00
abstract:AIM:To evaluate the role of computed tomography (CT) after herniography in the diagnosis and management of primary and recurrent groin hernias not detectable on clinical examination. MATERIAL AND METHODS:Fifty-one patients underwent CT post-herniography over a 6-year period for suspected primary or recurrent inguinal ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2004.02.013
更新日期:2005-02-01 00:00:00
abstract::Seronegative spondyloarthritis (SpA) represents a group of diseases that share certain genetic, clinical, and radiographic features. Enthesitis, inflammation at the site of tendon insertion into the bone, involving both the axial and the peripheral joints, is an important sign of SpA. Clinical diagnosis of enthesitis,...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2012.07.018
更新日期:2013-03-01 00:00:00
abstract::We reviewed the initial imaging studies of 283 children with urinary tract infection in order to decide on the most effective approach. A voiding cystogram was performed in all, complemented by either urography (147 patients), ultrasonography (65), or both (71 patients). In the latter group there was good correlation ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(89)80031-5
更新日期:1989-01-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(99)90563-9
更新日期:1999-05-01 00:00:00
abstract::Small intestinal tumours are rare, forming 1% of all gastrointestinal tumours; most occur in the duodenum. Villous adenomas form only a very small proportion of the duodenal tumours. They usually occur in the periampullary region and show a marked propensity for malignant change. The usual mode of presentation is with...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80040-6
更新日期:1992-07-01 00:00:00
abstract:AIM:To validate an imaging protocol for the management of solitary central cartilage tumours (CCTs) of the proximal humerus and around the knee. MATERIALS AND METHODS:Over a 10-year period, 387 patients were identified with a CCT in the proximal humerus, distal femur, and proximal tibia, who were referred to a single ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2019.08.017
更新日期:2019-12-01 00:00:00
abstract::Surgical anastomosis between branches of the external and internal carotid arteries may be beneficial in selected cases of transient ischaemic attacks and reversible ischaemic neurological deficit. It is the responsibility of the radiologist, at the time of initial angiographic evaluation, to recognise patients who mi...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(79)80197-x
更新日期:1979-09-01 00:00:00
abstract:AIMS:To report the magnetic resonance imaging (MRI) findings of osteomalacic insufficiency fractures of the pelvis. MATERIALS AND METHODS:In all, 12 persons presenting with chronic pelvic pain and with a definitive diagnosis of osteomalacia (OM) were enrolled in this study. Radiological work-up included direct radiogr...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2004.04.021
更新日期:2005-01-01 00:00:00
abstract::In this prospective study computed tomography (CT) was used to monitor the response of compression therapy in 27 patients with chronic unilateral lymphoedema over a 12 week period. Computed tomography examination of abnormal and normal limbs (proximal and distal portions) was performed in the first, third and 12th wee...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)83188-5
更新日期:1995-08-01 00:00:00
abstract:AIM:To evaluate the safety and efficacy of computed tomography (CT)-guided percutaneous fine-needle aspiration biopsy (FNAB) of pancreatic masses that traverses the gastrointestinal tract or solid viscera. MATERIALS AND METHODS:From January 2002 to December 2012, 144 patients underwent 165 CT-guided biopsies of pancre...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2014.05.111
更新日期:2014-10-01 00:00:00
abstract:AIM:To investigate the clinical value of diffusion tensor imaging (DTI) in assessing renal function changes in diabetic patients with early-stage chronic kidney disease (CKD), and the relationship of DTI parameters with estimated glomerular filtration rate (eGFR) and urinary biomarkers. MATERIALS AND METHODS:Thirty-si...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2018.09.011
更新日期:2019-02-01 00:00:00
abstract::The creation of an intrahepatic portosystemic shunt via a transjugular approach (TIPS) is an interventional radiological procedure used to treat the complications of portal hypertension. TIPS insertion is principally indicated to prevent or arrest variceal bleeding when medical or endoscopic treatments fail, and in th...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2008.09.017
更新日期:2009-07-01 00:00:00
abstract::The reduced lung cancer mortality observed with low-dose computed tomography (LDCT) screening in the National Lung Screening Trial (NLST) has led to annual screening in the United States as a covered benefit by both private insurers and the federal health insurance programme, the Centers for Medicare and Medicaid Serv...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2016.12.003
更新日期:2017-05-01 00:00:00