Pancreatic proteases and oxygen-derived free radicals in acute ischemic enteropathy.

Abstract:

:The specific susceptibility of the intestinal mucosa to low blood flow states is related to the "physiologic" makeup of the intestinal milieu. Pancreatic proteases appear to play a crucial role in the ischemic autodigestion of the intestinal mucosa. Moreover, trypsin can activate the conversion of xanthine dehydrogenase into superoxide radicals producing xanthine oxidase. Oxygen-derived free radicals account for at least part of the damage to the postischemic intestinal mucosa.

journal_name

Surgery

journal_title

Surgery

authors

Bounous G

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

92-4

issue

1

eissn

0039-6060

issn

1532-7361

pii

0039-6060(86)90208-4

journal_volume

99

pub_type

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