Abstract：
BACKGROUND:Less invasive operations such as laparoscopic surgery have been developed for treating gastrointestinal malignancies. However, the advantages of video-assisted thoracoscopic surgery for esophageal cancer (VATS-e) with regard to postoperative morbidity and mortality remains controversial. METHODS:We investigated the postoperative clinical course of patients who underwent esophagectomy for esophageal cancer in terms of systemic inflammatory response syndrome (SIRS) induced by VATS-e (VATS-e group) or conventional open surgery (OS group) combined with laparoscopic gastric tube reconstruction. RESULTS:Compared with the OS group (n = 27), the VATS-e group (n = 22) had a greater thoracic operation time (VATS-e versus OS, 181 ± 56 vs 143 ± 45 minutes, respectively), and lesser duration of stay in the intensive care unit (17 ± 2 vs 32 ± 21 hours, respectively). The VATS-e group also had a lesser SIRS duration (1.5 vs 4.3 days), a lesser incidence of SIRS, a lesser number of positive SIRS criteria, and lesser serum interleukin-6 levels immediately after operation and on postoperative day (POD) 1. The heart rate in the VATS-e group was less than that in the OS group on POD 3. The respiratory rate in the VATS-e group was significantly less than that in the OS group on PODs 3, 5, and 7. Although no difference was observed in the frequencies of postoperative complications between the 2 groups, the VATS-e group had less postoperative pneumonia. CONCLUSION:VATS-e attenuates postoperative SIRS, and is therefore a potentially less invasive operative procedure.
journal_name
Surgeryjournal_title
Surgeryauthors
Tsujimoto H,Takahata R,Nomura S,Yaguchi Y,Kumano I,Matsumoto Y,Yoshida K,Horiguchi H,Hiraki S,Ono S,Yamamoto J,Hase Kdoi
10.1016/j.surg.2011.12.006subject
Has Abstractpub_date
2012-05-01 00:00:00pages
667-73issue
5eissn
0039-6060issn
1532-7361pii
S0039-6060(11)00688-Xjournal_volume
151pub_type
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