Abstract：
BACKGROUND:Upper abdominal surgery is associated with severe postoperative pain and a concomitant reduction in pulmonary function and oxygen saturation. Laparoscopic cholecystectomy is said to result in less postoperative pain compared with open cholecystectomy. METHODS:In a pragmatic, randomized trial, postoperative pain, opiate analgesic consumption, oxygen saturation, and pulmonary function (forced vital capacity, forced expiratory volume in 1 second, and peak expiratory flow rate) were assessed after laparoscopic (n = 67) and minilaparotomy (n = 65) cholecystectomy. RESULTS:Compared with minilaparotomy cholecystectomy, laparoscopic cholecystectomy was associated with lower linear analogue pain scores (median 40 vs 59, p < 0.001), lower patient-controlled morphine consumption (median 22 vs 40 mg, p < 0.001), a smaller reduction in postoperative pulmonary function (mean peak expiratory flow rate 64% of preoperative value vs 49%, p < 0.001), and better oxygen saturation (mean 92.9% vs 91.2%, p = 0.008). CONCLUSIONS:This study confirms that the postoperative pain and pulmonary changes associated with upper abdominal surgery are significantly reduced by the laparoscopic technique. These findings suggest that laparoscopic cholecystectomy may result in a reduced risk of postoperative pulmonary complications.
journal_name
Surgeryjournal_title
Surgeryauthors
McMahon AJ,Russell IT,Ramsay G,Sunderland G,Baxter JN,Anderson JR,Galloway D,O'Dwyer PJsubject
Has Abstractpub_date
1994-05-01 00:00:00pages
533-9issue
5eissn
0039-6060issn
1532-7361journal_volume
115pub_type
临床试验,杂志文章,随机对照试验相关文献
SURGERY文献大全abstract：BACKGROUND:Although fine-needle aspiration (FNA) is 90% sensitive in the detection of papillary carcinoma (PC) of the thyroid, its specificity has been reported as low as 52%. Consequently, patients who have an FNA suspicious for PC may undergo operation for a benign process. The ribonucleoprotein telomerase has been n...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/s0039-6060(97)90219-1
更新日期：1997-12-01 00:00:00
abstract：:One possible cause of pulmonary failure after trauma is the type of asanguinous fluid used for resuscitation, i.e., crystalloid or colloid. To investigate this issue, patients having a laparotomy for trauma randomly received either Ringer's lactate (RLS) alone or Ringer's lactate with albumin (ALB). Both groups receiv...
journal_title：Surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1977-06-01 00:00:00
abstract：:The proliferation of transplantation programs has not been paralleled by a similar increase in the availability of organ donors. Between 1984 and 1987, 104 orthotopic heart transplantations were performed at Loyola University Medical Center. During the same period, 25 patients died while awaiting a donor organ. To red...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1990-10-01 00:00:00
abstract：BACKGROUND:Interleukin (IL)-10 is a potent antiinflammatory cytokine inhibiting the release of tumor necrosis factor--alpha (TNF-alpha) and IL-8 by activated macrophages and polymorphonuclear leukocytes. Cardiopulmonary bypass (CPB) represents a unique situation where an inflammatory reaction is predictably induced. Th...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/s0039-6060(96)80217-0
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND:After resection of advanced abdominal neuroblastoma, children may have persistent postoperative diarrhea. Until recently, the magnitude of this problem had not been appreciated. METHODS:To assess the incidence, severity, and management of chronic postoperative diarrhea in these patients, we reviewed the cas...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1067/msy.1998.88092
更新日期：1998-05-01 00:00:00
abstract：BACKGROUND:Misdiagnosed primary hyperparathyroidism (PHPT) during thyroid surgery may lead to a difficult reoperation. Because PHPT is often asymptomatic, calcium measurements have been recommended before thyroid surgery, but no study has focused on the results of a prospective PHPT screening. METHODS:The prospective ...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1067/msy.2002.121379
更新日期：2002-03-01 00:00:00
abstract：BACKGROUND:Diaphragm pacing (DP) can replace mechanical ventilation in tetraplegics and in trials has assisted respiration in amyotrophic lateral sclerosis patients. This report describes results of DP in patients with cardiac pacemakers. METHODS:Prospective, single-center and multicenter, nonrandomized, controlled, i...
journal_title：Surgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.surg.2010.07.008
更新日期：2010-10-01 00:00:00
abstract：:Minced adult human, rat, and dog pancreatic fragments were cultured under various conditions in an attempt to selectively purify pancreatic islet tissue from exocrine digestive enzymes. Islet purification was assessed by measuring tissue insulin and amylase concentrations, proportional to islet beta cell mass and exoc...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1976-08-01 00:00:00
abstract：BACKGROUND:Neoadjuvant chemotherapy (NACT) has been frequently used for locally advanced esophageal squamous cell cancer (ESCC). It is therefore important to establish criteria for evaluating the response to NACT based on survival analysis. METHODS:This study analyzed 100 patients with ESCC (cT1, 2/3/4:25/57/18, cN0/1...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2010.02.016
更新日期：2010-11-01 00:00:00
abstract：INTRODUCTION:End-stage renal disease (ESRD) is associated with poor medical outcomes. This study aimed to compare early outcomes of elective and emergency operation for diverticulitis among older adults with and without a diagnosis of ESRD. METHODS:Patients 65 years of age and older with a primary diagnosis of diverti...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2014.03.034
更新日期：2014-08-01 00:00:00
abstract：BACKGROUND:Hepatotoxicity from neoadjuvant chemotherapy before liver resection for colorectal metastases (CRLM) has been recently reported. The purpose of the present study was to evaluate the prevalence and the clinical relevance of this phenomenon. It was a retrospective study conducted at an academic secondary refer...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2009.01.004
更新日期：2010-02-01 00:00:00
abstract：:Until recently, vascular surgeons have had to make judgments based on an impression of their experiences rather than upon the actual facts. Presently, with the simplified and less costly use of computers, the establishment of a computerized data base is feasible. Our goal had been to develop a system suitable for micr...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1980-12-01 00:00:00
abstract：BACKGROUND:Certain behavioral traits and inadequate social support are known risk factors for complications after cancer surgery. Despite their importance, it is unclear whether conventional patient preoperative evaluation captures them. This study was conducted to assess concordance between documentation and patient s...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2019.04.015
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:The presence or absence of lymph node metastases is known to be an important prognostic factor for patients with pancreatic cancer. Few studies have investigated the ratio of the number of lymph nodes harboring metastatic cancer to the total number of lymph nodes examined (lymph node ratio [LNR]) with regard...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2006.12.013
更新日期：2007-05-01 00:00:00
abstract：BACKGROUND:Major operative injury initiates immunologic changes that may result in a systemic inflammatory response, leading to organ dysfunction/sepsis. Catecholamines seem to be key mediators. The effects of beta(2) receptor blockade in vitro and in vivo before and after operative injury were studied to clarify their...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2008.09.013
更新日期：2009-02-01 00:00:00
abstract：:To test the hypothesis that nonprotein calorie intake and nitrogen intake are equally important in establishing positive nitrogen balance, weight gain, and serum protein response in the depleted primate treated with total parenteral nutrition (TPN), 10 adult male chair-adapted primates (Macaque fascicularis) were stud...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:We have previously shown that the timing of surgical removal of an estrogen-receptor-bearing mammary adenocarcinoma within the estrous cycle of the female C3HeB/FeJ mouse profoundly influences the frequency of subsequent tumor cell metastasis. In order to investigate the role of the immune response in this phenomenon,...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1988-08-01 00:00:00
abstract：:The shear stress resistance of cultured human endothelium was investigated on 6 mm polytetrafluoroethylene vascular grafts. Endothelial cell attachment was promoted by precoating the grafts with fibrin glue, which contained human fibronectin and inhibitors of fibrinolysis (aprotinin and tranexam acid). To evaluate the...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1989-04-01 00:00:00
abstract：BACKGROUND:The reconstruction of outflow is a crucial step in living donor liver transplantation. This study describes a suitable technique that uses synthetic vascular conduits in presence of multiple draining veins of right lobe of liver and the outcome of the recipients to evaluate safety of using multiple synthetic...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2015.03.018
更新日期：2015-11-01 00:00:00
abstract：:Adenocarcinomas of the colon arise from adenomatous polyps. We hypothesized that sucrase-isomaltase (SI), a glycoprotein hydrolase, found in normal small intestine, fetal colon, and colon carcinomas is a marker associated with progression of adenomatous polyps with dysplasia to adenocarcinomas. To examine this hypothe...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1990-08-01 00:00:00
abstract：:Postendarterectomy platelet deposition and thrombus formation may play an important role not only in vessel wall healing but also in the small incidence of postoperative cerebral ischemia and postoperative stenosis. A study has been performed using a canine model to investigate the healing response to carotid endarter...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1983-03-01 00:00:00
abstract：BACKGROUND:The effects of intestinal inflammation on the central nervous system are unknown. The dorsal motor nucleus of the vagus (DMNV) integrates peripheral and central signals and sends efferent signals to the gastrointestinal system. The purpose of this study was to determine the effects of intestinal inflammation...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2008.03.042
更新日期：2008-08-01 00:00:00
abstract：:Direct measurement of the femoral artery pressure before operation has been used to predict the postoperative change in ankle and toe pressure in 102 limbs (83 patients) that underwent aortoiliac surgery for the treatment of atherosclerotic occlusion or stenosis affecting both the aortoiliac and femoral artery segment...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1982-07-01 00:00:00
abstract：BACKGROUND:Management of critically ill patients is a challenge in low resource settings where there is a paucity of trained staff, infrastructure, resources, and drugs. We aimed to study the characteristics of surgical patients admitted in intensive care unit in a limited resource setting and determine factors associa...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2019.04.010
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:Interleukin (IL)-18 is a proinflammatory cytokine involved in the regulation of cell-mediated and innate immune responses to infection, trauma, and inflammation. Elevated levels of IL-18 have been noted to correlate with organ dysfunction after injury. This study evaluates the relationship between IL-18 prom...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1067/msy.2003.248
更新日期：2003-08-01 00:00:00
abstract：BACKGROUND:Although hepatic resection is the most reliable treatment for hepatocellular carcinoma, impaired liver function because of cirrhosis or chronic hepatitis contributes to relatively high rates of postoperative complications. We have reviewed a series of hepatectomies at our institution and investigated risk fa...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：INTRODUCTION:Hypothermia is a well-known risk factor for postoperative complications because it prolongs the monocyte inflammatory response. The purpose of this study was to investigate whether temperature-activated ion channels (transient receptor protein channels [TRP] A1 and V1) mediate the effects of temperature on...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2015.03.065
更新日期：2015-09-01 00:00:00
abstract：:Coexistent caval and portal hypertension was recognized on preoperative angiographic study of a patient with cirrhosis and variceal bleeding. This hemodynamic situation can preclude adequate reduction of portal hypertension by portasystemic shunt and can result in fatal postoperative bleeding. Resection of a very larg...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1980-05-01 00:00:00
abstract：:Malignant intra-abdominal neuroendocrine tumors are rare; consequently, a standard chemotherapeutic protocol for patients with unresectable disease has not been established. This prompted a review of our experience with dimethyltriazeno imidazole carboxamide (dacarbazine) (DTIC) treatment for these tumors. From 1976 t...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1987-12-01 00:00:00
abstract：:Cadaver allograft skin, porcine xenograft skin, and amniotic membranes have been proved to be adequate temporary thermal wound coverings in four clinical situations: coverage of shallow wounds while awaiting epithelialization (SW), coverage of deep wounds after eschar excision (DEW), coverage of widely meshed autograf...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1986-10-01 00:00:00
