Abstract：
BACKGROUND:This study was conducted to identify the relevant cutoff value and to evaluate the usefulness of postoperative-stimulated serum thyroglobulin (Tg) at the time of (131)I ablation for the prediction of disease status in patients with differentiated thyroid carcinoma (DTC) who received high-dose (131)I ablation therapy after total thyroidectomy. METHODS:We analyzed 218 consecutively enrolled patients who were diagnosed with DTC and underwent total thyroidectomy. All patients underwent (131)I ablation at doses of 100-200 mCi, and stimulated serum Tg was measured at the time of (131)I ablation therapy. To assess disease-free status after (131)I ablation therapy, stimulated serum Tg levels, diagnostic whole-body scan (DxWBS) and neck ultrasonography (US) were performed 6-12 months after (131)I ablation. RESULTS:The relevant cutoff value of postoperative stimulated Tg for the prediction of disease-free status was 2 ng/mL. A total of 138 patients (63.3%) showed values of <2 ng/mL. Postoperative-stimulated Tg < 2 ng/mL had a negative predictive value of 94.9%, which increased to 97.7% when low Tg was combined with negative neck US findings. CONCLUSION:Postoperative-stimulated Tg at the time of (131)I remnant ablation is a useful biochemical marker for the prediction of disease status in patients with DTC. When high-dose (131)I remnant ablation is performed after total thyroidectomy, the stimulated Tg measurement and DxWBS that are usually performed 6-12 months after (131)I ablation therapy may be skipped, at least in low- and intermediate-risk patients with postoperative stimulated Tg of < 2 ng/mL and negative neck US findings.
journal_name
Surgeryjournal_title
Surgeryauthors
Lee JI,Chung YJ,Cho BY,Chong S,Seok JW,Park SJdoi
10.1016/j.surg.2012.12.008subject
Has Abstractpub_date
2013-06-01 00:00:00pages
828-35issue
6eissn
0039-6060issn
1532-7361pii
S0039-6060(12)00756-8journal_volume
153pub_type
杂志文章相关文献
SURGERY文献大全abstract：:The main goal of surgery for retroperitoneal fibrosis is to free the ureters from sclerotic tissue and pressure them from further extension of the disease; the omentum may be used as an efficient barrier against recurrence of fibrosis. We present 11 patients with idiopathic retroperitoneal fibrosis treated with ureter...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1982-02-01 00:00:00
abstract：BACKGROUND:In clinically node-negative patients with differentiated thyroid cancer (DTC), indications for routine central lymph node dissection (RCLD) are the subject of intensive research, and surgeons are divided between the pros and cons of this surgery. To better define the role of neck dissection in the treatment ...
journal_title：Surgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.surg.2014.02.010
更新日期：2014-06-01 00:00:00
abstract：:The effect of wood smoke inhalation (SI) on pulmonary vascular permeability was studied in open-chested, anesthetized dogs. Animals were divided into two groups. A prenodal lymphatic vessel was cannulated in group I (n = 7), and baseline (BL) lung lymph flow (QL) and lymph (CL) and plasma (CP) protein concentrations w...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1989-04-01 00:00:00
abstract：:Over a three year period, 28 children or young adults up to 20 years of age underwent 60 thoracotomies for pulmonary metastatic osteogenic sarcoma. These patients also received adjuvant chemotherapy. Sixteen of the 28 patients are currently alive and 13 of these are free of disease. The patients have been followed for...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1978-09-01 00:00:00
abstract：:The findings of decreased adenosine triphosphate (ATP) levels in liver, kidney, and other tissues of animals in hemorrhagic shock were the rationale for previous experimental attempts to improve cell function by administration of fluids that contained high concentrations of ATP. The beneficial effects of this resuscit...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1987-09-01 00:00:00
abstract：BACKGROUND:The long-term outcome of bilateral adrenalectomy in the management of patients with Cushing's syndrome has not been previously well studied. METHODS:We reviewed our long-term results in 34 patients treated with bilateral adrenalectomy between 1983 and the present. Fourteen presented with occult or metastati...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：BACKGROUND:Ventral abdominal wall hernias are common lesions and may be associated with life-threatening complications. The application of laparoscopic principles to the treatment of ventral hernias has reduced recurrence rates from a range of 25% to 52% to a range of 3.4% to 9%. In this study, we review our experience...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/s0039-6060(03)00283-6
更新日期：2003-10-01 00:00:00
abstract：:The proliferative defects observed in phagocytic stem cells after major thermal injuries may be caused by an inadequate production of colony-stimulating factors (CSFs), a family of hemopoietic cytokines necessary for the production and function of granulocytes and monocytes. In this study a biologic response modifier ...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：:A rat gastric chamber preparation was used to determine the interrelations between H+ back diffusion, mucosal blood flow, the area of mucosa treated with bile salts and ulcer formation. The rate of H+ back diffusion was found to be dependent on both mucosal blood flow and the area of mucosa exposed to bile salts. It i...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1978-03-01 00:00:00
abstract：BACKGROUND:Many postoperative concerns after common general operative procedures may be addressed over the phone, thereby saving time and resources for both the patient and surgeon. METHODS:Over a 6-month time period, patients who underwent laparoscopic cholecystectomy, appendectomy for uncomplicated appendicitis, and...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2013.05.005
更新日期：2013-10-01 00:00:00
abstract：:A dominant belief throughout the last half of the 1970s was that operative rates in the United States continued to show steady increases. This strongly suggested that an excessive number of operations were being performed. Unsubstantiated statements regarding surgical rates have been accepted at face value, and little...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1981-02-01 00:00:00
abstract：BACKGROUND:Postoperative ileus, a transient impairment of bowel motility initiated by intestinal inflammation, is common after an abdominal operation and leads to increased hospital stays and costs. Hydrogen has potent anti-inflammatory and antioxidant properties and potential therapeutic value. Solubilized hydrogen ma...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2016.05.026
更新日期：2016-09-01 00:00:00
abstract：BACKGROUND:Because retrospective clinical studies yield conflicting results and experimental data are completely absent, this study was performed to determine whether anastomotic repair in the intestine deteriorates with age. METHODS:Ileal and colonic anastomoses were constructed in two groups of healthy rats, ages 2 ...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/s0039-6060(96)80207-8
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND:Primary tissue failure is the most frequent indication for reoperation in patients with a mitral bioprosthetic valve (MBPV). Complete excision of the bioprosthesis is time-consuming and may be complicated by cardiac rupture at the atrioventricular junction or the posterior left ventricular wall where a strut...
journal_title：Surgery
pub_type： 杂志文章,评审
doi：10.1016/s0039-6060(05)80033-9
更新日期：1995-10-01 00:00:00
abstract：BACKGROUND:Controversy exists about the routes of invasion (extrathyroidal versus lymphogenic extension) when differentiated carcinoma (DTC) and medullary thyroid carcinoma (MTC) invade the cervicovisceral axis (ie, larynx, trachea, esophagus). METHODS:We carried out an institutional analysis, from November 1994 to Oc...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1067/msy.2001.108699
更新日期：2001-01-01 00:00:00
abstract：:Although well accepted in pediatric patients, nonoperative management of blunt hepatic trauma in adults remains controversial. From January 1981 through May 1987, 66 adults were identified with blunt hepatic trauma that had been confirmed by abdominal exploration or abdominal computed tomography (CT): 46 underwent imm...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1988-10-01 00:00:00
abstract：:The possibility of vagal reinnervation to intrasplenic islet grafts was examined by measuring portal insulin response to electric stimulation of the dorsal vagus nerve in autografted dogs. Grafted islets responded appropriately to an exogenous cholinergic agent given intravenously. However, no insulin secretory respon...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1986-12-01 00:00:00
abstract：:During the 23-year period from January 1959 to February 1982, 142 patients (78 men and 64 women) underwent arterial reconstructive operations for obstruction of the brachiocephalic arteries. A single vessel was involved in 75% and multiple vessels were involved in 25% of the cases. Distal involvement of internal carot...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1983-11-01 00:00:00
abstract：:A 5 MHz continuous-wave Doppler probe was used intraoperatively to evaluate 25 in situ saphenous vein bypass grafts. At least one arteriovenous fistula per case and five retained competent posterior valvular leaflets were identified before completion angiography. The Doppler was able to distinguish a retained valve fr...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1984-11-01 00:00:00
abstract：:A retrospective study was performed on 65 patients with intractable angina and subtotal coronary occlusions undergoing aortocoronary artery bypass (ACB) to determine whether the local occlusion (L.O.) or the ischemic arrest (I.A.) technique was perferable in performing the distal coronary artery bypass. In 23 patients...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1975-10-01 00:00:00
abstract：BACKGROUND:The purpose of this study was to investigate the effects of treating human thyroid cancer cell lines with demethylating agents and histone deacetylase (HDAC) inhibitors to see if they would downregulate expression and activity of the matrix metalloproteinases (MMP)-2 and MMP-9, resulting in inhibition of gro...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2010.10.007
更新日期：2011-04-01 00:00:00
abstract：:That the fetus swallows amniotic fluid and has the capability of intestinal absorption of protein and carbohydrate is known, but its significance in fetal nutrition is not clear. We have infused nutrient solutions of dextrose and amino acids intra-amniotically in a chronic third-trimester fetal rabbit model and examin...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1985-09-01 00:00:00
abstract：:Four hundred forty-one patients who were operated on for primary hyperparathyroidism were observed for up to 22 years. Mortality was significantly higher than expected during the first postoperative years, for both men and women. This was predominantly due to a higher than expected incidence of diseases of the circula...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1987-07-01 00:00:00
abstract：:Pancreatic abscess is a highly lethal sequela of pancreatitis. The purpose of this study was to identify clinical and laboratory factors associated with the antecedent episode of pancreatitis or at the time of manifestation of a pancreatic abscess and factors related to its treatment that might have prognostic signifi...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1984-09-01 00:00:00
abstract：:The immunoregulatory events leading to the generation of suppressor T cells after burn injury were studied by means of a mouse burn model. Immunoresponsiveness was assessed on various postburn days with a primary in vitro mixed lymphocyte reaction (MLR). Responses of burned mice were depressed between 3 and 14 days af...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1984-06-01 00:00:00
abstract：:Sixty patients with recurrent ulcers after vagotomy were treated by partial gastrectomy without revagotomy. One patient died after surgery. Seven others died of unrelated causes and one patient was lost to follow-up before 5 years, without rerecurrence having been diagnosed. Of the remaining 51 patients, one underwent...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1986-05-01 00:00:00
abstract：BACKGROUND:Alcoholism is the leading cause of end-stage liver failure in the United States, but the application of liver transplantation to the treatment of alcoholic liver disease remains controversial because of medical and ethical concerns. Information about the outcome of patients who undergo transplantation for al...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：BACKGROUND:Wound complications after lower extremity arterial reconstruction can range from a minor lymphatic leak that causes minimal disability to a severe infection that jeopardizes the limb and life of the affected patient. This study was designed to define more clearly the incidence, severity, and the cost of thes...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/s0039-6060(96)80135-8
更新日期：1996-04-01 00:00:00
abstract：:The extrahepatic diversion of essential splanchnic hepatotrophic factors may cause the liver atrophy and insufficiency that follows portacaval shunting. To investigate this, control dogs with end-to-side portacaval shunts (control-PCS, n = 6) were compared with dogs shunted 1 month after intraportal pancreatic islet a...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1989-08-01 00:00:00
abstract：BACKGROUND:Misdiagnosed primary hyperparathyroidism (PHPT) during thyroid surgery may lead to a difficult reoperation. Because PHPT is often asymptomatic, calcium measurements have been recommended before thyroid surgery, but no study has focused on the results of a prospective PHPT screening. METHODS:The prospective ...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1067/msy.2002.121379
更新日期：2002-03-01 00:00:00
