Modulation of matrix metalloproteinase activity in human thyroid cancer cell lines using demethylating agents and histone deacetylase inhibitors.

abstract：BACKGROUND:Anastomotic leakage represents a major complication after anterior resection of the rectum. The incidence of anastomotic leakage varies considerably among clinical studies in part owing to the lack of a standardized definition of this complication. The aim of the present article was to propose a definition a...

journal_title：Surgery

authors： Rahbari NN,Weitz J,Hohenberger W,Heald RJ,Moran B,Ulrich A,Holm T,Wong WD,Tiret E,Moriya Y,Laurberg S,den Dulk M,van de Velde C,Büchler MW

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Biologic mesh choice in ventral hernia repair is challenging due to lack of prospective data. This study examines long-term, single-center biologic mesh outcomes. METHODS:Prospective operative outcomes data was queried for open ventral hernia repair with biologic mesh. Univariate and multivariate analysis w...

journal_title：Surgery

authors： Huntington CR,Cox TC,Blair LJ,Schell S,Randolph D,Prasad T,Lincourt A,Heniford BT,Augenstein VA

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the genotype-phenotype relationship of pancreatic neuroendocrine tumors in patients with multiple endocrine neoplasia type 1 treated at our institution. METHODS:We conducted a retrospective chart review of all patients with multiple endocrine neoplasia type 1 treated...

journal_title：Surgery

authors： Christakis I,Qiu W,Hyde SM,Cote GJ,Grubbs EG,Perrier ND,Lee JE

更新日期：2018-01-01 00:00:00

abstract：:The outcome of 29 patients who underwent lung resection for treatment of metastatic malignant melanoma from January 1976 to November 1988 was studied. Twenty-two patients underwent total resection for cure of all apparent metastatic disease, whereas seven patients did not undergo total resection. Of the 22 patients wh...

journal_title：Surgery

authors： Karp NS,Boyd A,DePan HJ,Harris MN,Roses DF

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Bilateral axillo-breast approach (BABA) robotic thyroidectomy (RoT) has good postoperative and excellent cosmetic outcomes. To assess the surgical completeness of BABA RoT, it was compared to open thyroidectomy (OT) after propensity score matching of the cohorts. METHODS:Between 2008 and 2010, 760 patients ...

journal_title：Surgery

authors： Lee KE,Koo do H,Im HJ,Park SK,Choi JY,Paeng JC,Chung JK,Oh SK,Youn YK

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:New surgeons are faced with inadequate mentoring when first entering practice. Our study examined challenges faced by young surgeons during their transition in practice and their mentoring experience when entering practice. METHODS:An article-based survey was mailed in August 2019 to general, colorectal, va...

journal_title：Surgery

authors： Stolarski A,He K,Sell N,Chugh P,O'Neal P,Smink DS,Whang E,Kristo G

更新日期：2020-12-28 00:00:00

abstract：INTRODUCTION:A diverting stoma is often performed at the time of low anterior resection (LAR) for rectal cancer after neoadjuvant chemoradiation (nCRT) to protect the anastomosis. The aim of this study was to compare surgical outcomes in large cohorts of mid-high rectal cancer patients undergoing LAR after nCRT with an...

journal_title：Surgery

authors： Messaris E,Connelly TM,Kulaylat AN,Miller J,Gusani NJ,Ortenzi G,Wong J,Bhayani N

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Propranolol has been shown previously to restore bone marrow function and improve anemia after lung contusion/hemorrhagic shock. We hypothesized that daily clonidine administration would inhibit central sympathetic outflow and restore bone marrow function in our rodent model of lung contusion/hemorrhagic sho...

journal_title：Surgery

authors： Alamo IG,Kannan KB,Ramos H,Loftus TJ,Efron PA,Mohr AM

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Physiologic and psychological stress are commonly experienced by operating room (OR) personnel, yet there is little research about the stress levels in OR teams and their impact on performance. Previously published procedures to measure physiologic activation are invasive and impractical for the OR. The purp...

journal_title：Surgery

authors： Phitayakorn R,Minehart RD,Pian-Smith MC,Hemingway MW,Petrusa ER

更新日期：2015-11-01 00:00:00

abstract：:This study evaluated the mixed leukocyte culture (MLC) technique to quantitate differences in kidney allograft survival between unrelated animals. Each of five beagles received two heterotopic kidney allografts, one from a mongrel dog showing high MLC stimulation and one from a second mongrel dog showing a low MLC sti...

journal_title：Surgery

authors： Kahn DR,Bach FH,Dufek JH,Burkholder PM,Dacumos GC

更新日期：1975-07-01 00:00:00

abstract：:The intravenous infusion of amino acid and carbohydrate solutions is a well-established technique for nutritional support of the pediatric surgical patient. By using peripheral veins for total parenteral nutrition (TPN), weight gain can be achieved and the complications of central venous catheters avoided. Over a 2-ye...

journal_title：Surgery

authors： Benner JW,Coran AG,Weintraub WH,Wesley JR

更新日期：1979-09-01 00:00:00

abstract：BACKGROUND:Gross vascular invasion is a well-established prognostic indicator in hepatocellular carcinoma (HCC), but the biological significance of microscopic invasion remains unclear. METHODS:Curatively resected primary HCCs were classified retrospectively into 3 groups: HCCs without vascular invasion (V0), HCCs wit...

journal_title：Surgery

authors： Tanaka S,Mogushi K,Yasen M,Noguchi N,Kudo A,Nakamura N,Ito K,Miki Y,Inazawa J,Tanaka H,Arii S

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Total parenteral nutrition is an etiologic factor in the formation of biliary sludge. We studied whether enteral nutrition is also a risk factor for sludge. METHODS:Fifty patients with a needle catheter jejunostomy (NCJ) placed during a major abdominal operation underwent preoperative and weekly postoperati...

journal_title：Surgery

authors： Schwesinger WH,Page CP,Strodel WE,Ghiatis AA,Chopra S,Gross GW,Sirinek KR

更新日期：1998-10-01 00:00:00

abstract：:During a 3-year period (1984 through 1987), 40 patients with smoke inhalation, cutaneous burns, or a combination of both injuries were studied. Injuries were assigned to the three categories on the basis of bronchoscopic findings and clinical history. Eleven patients had simultaneously sustained a common smoke-inhalat...

journal_title：Surgery

authors： Herndon DN,Barrow RE,Traber DL,Rutan TC,Rutan RL,Abston S

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:Barriers to trauma care for rural populations are well documented, but little is known about the magnitude of urban-rural disparities in injury mortality. This study sought to quantify differences in injury mortality comparing rural and nonrural residents with traumatic injuries. METHODS:Using data from the...

journal_title：Surgery

authors： Jarman MP,Castillo RC,Carlini AR,Kodadek LM,Haider AH

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Prolonged warm ischemic injury in non-heart-beating donors (NHBDs) significantly affects hepatic allograft function after liver transplantation (LTx). METHODS:The effects of FK506 and the platelet activating factor antagonist E5880 on postoperative function of hepatic allografts procured from NHBDs were eva...

journal_title：Surgery

authors： Takada Y,Taniguchi H,Fukunaga K,Yuzawa K,Otsuka M,Todoroki T,Iijima T,Fukao K

更新日期：1998-06-01 00:00:00

abstract：:We studied 28 patients who had undergone 30 operations for pheochromocytoma since 1964. The tumor types included bilateral, extra-adrenal, malignant, recurrent, and multiple endocrine neoplasia, with 20 tumors confined to the adrenal gland. The preoperative studies used to localize the tumor included ultrasonography, ...

journal_title：Surgery

authors： Cullen ML,Staren ED,Straus AK,Doolas A,Shah R,Patel S,Economou SG

更新日期：1985-11-01 00:00:00

abstract：:Abnormalities of the immune response are commonly observed after surgery. In many cases, they are part of a physiologic rather than of a pathologic response to trauma. In this study we show that after elective surgery in otherwise healthy subjects the B cell compartment is deeply affected, as documented by the appeara...

journal_title：Surgery

authors： Di Padova F,Durig M,Di Padova C,Pozzoli M,Tritapepe R

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:Clinical parameters influencing the effect of preoperative portal vein embolization (PVE) in hypertrophying the nonembolized lobe of patients with either normal or abnormal liver parenchyma and its effect upon portal pressure were examined to identify the patient population for whom this approach is most sui...

journal_title：Surgery

authors： Wakabayashi H,Ishimura K,Okano K,Karasawa Y,Goda F,Maeba T,Maeta H

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Patients undergoing ventral hernia repair (VHR) are at risk of an inadvertent enterotomy during surgery. Inadvertent enterotomies potentially contaminate the surgical field presenting a management dilemma for the surgeon. The aim of our study was to define the incidence and risk factors for a recognized inad...

journal_title：Surgery

authors： Krpata DM,Prabhu AS,Tastaldi L,Huang LC,Rosen MJ,Poulose BK

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor (VEGF) promotes tumor angioinvasion while VEGF-C is a potent lymphangiogenic factor. This study aims at evaluating serum VEGF (sVEGF) and sVEGF-C levels in recurrent papillary thyroid carcinoma (PTC) patients. METHODS:Serum samples were collected preoperatively from 85 pat...

journal_title：Surgery

authors： Yu XM,Lo CY,Lam AK,Lang BH,Leung P,Luk JM

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Although many randomized trials and other multicenter studies have demonstrated the benefits of carotid endarterectomy (CEA) in selected symptomatic and asymptomatic patients, including women, there is a remarkable lack of reports regarding the outcome of CEA with respect to sex. To analyze and compare the o...

journal_title：Surgery

authors： Ballotta E,Renon L,Da Giau G,Sarzo G,Abbruzzese E,Saladini M,Baracchini C,Meneghetti G

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Minority-serving hospitals have greater readmission rates after operative procedures including colectomy; however, little is known about the contribution of hospital factors to readmission risk and mortality in this setting. This study evaluated the impact of hospital factors on readmissions and inpatient mo...

journal_title：Surgery

authors： Hechenbleikner EM,Zheng C,Lawrence S,Hong Y,Shara NM,Johnson LB,Al-Refaie WB

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Interleukin (IL)-18 is a proinflammatory cytokine involved in the regulation of cell-mediated and innate immune responses to infection, trauma, and inflammation. Elevated levels of IL-18 have been noted to correlate with organ dysfunction after injury. This study evaluates the relationship between IL-18 prom...

journal_title：Surgery

authors： Stassen NA,Breit CM,Norfleet LA,Polk HC Jr

更新日期：2003-08-01 00:00:00

abstract：:Planned excisions of tumors involving the abdominal or chest wall should not be compromised because of lack of tissue for wound closure. Reconstruction with an inert polypropylene mesh provides a strong and stable covering for the defect. Mobilization of adjacent skin flaps to provide covering for the mesh is desirabl...

journal_title：Surgery

authors： Karakousis CP,Elias EG,Douglass HO Jr

更新日期：1975-10-01 00:00:00

abstract：BACKGROUND:The role of routine prophylactic central-neck lymph node dissection (CLND) for papillary thyroid cancer (PTC) remains controversial. We perform CLND for PTC only in patients with enlarged nodes as determined by preoperative ultrasound and intraoperative inspection and palpation. METHODS:We identified all pa...

journal_title：Surgery

authors： Shen WT,Ogawa L,Ruan D,Suh I,Duh QY,Clark OH

更新日期：2010-08-01 00:00:00

abstract：:With the aim of developing guidelines for investigation and management of adrenal incidentalomas, 2066 patients with adrenal masses were analyzed from a total of 61,054 computerized tomographic (CT) scans done from 1985 through 1989. Excluding patients with previous or concurrent malignancies, adrenal tumors localized...

journal_title：Surgery

authors： Herrera MF,Grant CS,van Heerden JA,Sheedy PF,Ilstrup DM

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Patient-reported outcome measures are being used increasingly to assess disease severity and response to surgery. The purpose of this study was to create and validate a patient-reported outcome measure for symptoms of thyroid enlargement and hyperparathyroidism, 2 conditions where the presence of preoperativ...

journal_title：Surgery

authors： Burneikis T,Colvin J,Jin J,Berber E,Krishnamurthy VD,Shin J,Siperstein A

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:We have previously reported that vascular inducible nitric oxide synthase (iNOS) gene transfer inhibits injury-induced intimal hyperplasia in vitro and in vivo. One mechanism by which NO may prevent intimal hyperplasia is by preserving the endothelium or promoting its regeneration. To study this possibility ...

journal_title：Surgery

authors： Tzeng E,Kim YM,Pitt BR,Lizonova A,Kovesdi I,Billiar TR

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Resumption of elective surgery during the current coronavirus disease 2019 pandemic crisis has been debated widely and largely discouraged. The aim of this prospective cohort study was to assess the feasibility of resuming elective operations during the current and possible future peaks of this coronavirus d...

journal_title：Surgery

authors： Gammeri E,Cillo GM,Sunthareswaran R,Magro T

更新日期：2020-10-01 00:00:00