Abstract:
:The outcome of 29 patients who underwent lung resection for treatment of metastatic malignant melanoma from January 1976 to November 1988 was studied. Twenty-two patients underwent total resection for cure of all apparent metastatic disease, whereas seven patients did not undergo total resection. Of the 22 patients who underwent curative resection, the median survival was 11 months, with a 2-year survival of 13.6% and a 5-year survival of 4.5%. Four patients who underwent curative resection are currently alive and free of disease, with one patient surviving more than 10 years. The patients who underwent palliative resection had a median survival of 5 months, only one patient living longer than 10 months. The difference in survival of the patients who underwent curative resection compared with palliative resection was statistically significant. The thickness of the primary cutaneous malignant melanoma, the presence of regional lymph node metastases, the disease-free interval from primary diagnosis to metastatic pulmonary disease, and whether one or two metastatic nodules were removed during curative lung resection were not statistically significant in altering survival. These results demonstrate that although prolonged survival for metastatic melanoma is rare, lung resection in selected patients may be associated with long-term survival.
journal_name
Surgeryjournal_title
Surgeryauthors
Karp NS,Boyd A,DePan HJ,Harris MN,Roses DFsubject
Has Abstractpub_date
1990-03-01 00:00:00pages
256-61issue
3eissn
0039-6060issn
1532-7361journal_volume
107pub_type
杂志文章相关文献
SURGERY文献大全abstract::The acute and chronic changes produced in canine femoral arteries by ischemia and by perfusion with D10W were examined by light and by scanning electron microscopy. Mild changes of injury characterized by medial and adventitial inflammation and an increase in intimal lining cells occur following 30 minutes of perfusio...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1977-05-01 00:00:00
abstract::To assess the relative importance of cardiac versus peripheral vascular failure in patients dying of septic shock, a series of 42 patients with documented septic shock was retrospectively evaluated. Patients were included in the study if serial hemodynamic and metabolic studies had been performed: the first one within...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1986-02-01 00:00:00
abstract:BACKGROUND:Obesity is known as a risk factor for intra- and postoperative complications in pancreatic operation. However, the operative outcomes in obese patients undergoing laparoscopic distal pancreatectomy remain unclear. METHODS:A total number of 423 patients underwent laparoscopic distal pancreatectomy at Oslo Un...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2016.05.046
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:We previously developed an intraoperative 10-point Surgical Apgar Score-based on blood loss, lowest heart rate, and lowest mean arterial pressure-to predict major complications after colorectal resection. However, because complications often arise after uncomplicated hospitalizations, we sought to evaluate w...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.01.015
更新日期:2010-09-01 00:00:00
abstract::One hundred five students in our surgical clerkship were evaluated independently by two faculty members, a chief resident, a written multiple-choice examination, and two oral examinations. Faculty and chief resident evaluations included a written explanation and a score from 1 (honors) to 5 (failing). Oral and written...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1984-07-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to compare faculty ratings between live versus video-recorded resident performances and faculty versus skills coaches' ratings of video-recorded resident performances. METHODS:PGY1 residents were observed, video-recorded, and rated during a Verification of Proficiency examina...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2012.03.016
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Primary hyperparathyroidism is associated with an increased cardiovascular morbidity and mortality. However, mechanisms underlying this association are currently unclear. As there is clear evidence of the independent role of aldosterone on the cardiovascular system, the aim of this study was to evaluate aldo...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2009.09.041
更新日期:2009-12-01 00:00:00
abstract::Intracellular pH provides an important measure of the adequacy of local tissue perfusion. The purpose of this study was to measure regional intracellular myocardial pH (impH) in the ischemic zone in vivo during experimental canine coronary occlusion, with and without coronary reperfusion. Twenty adult dogs were studie...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1987-08-01 00:00:00
abstract::Sixty patients with recurrent ulcers after vagotomy were treated by partial gastrectomy without revagotomy. One patient died after surgery. Seven others died of unrelated causes and one patient was lost to follow-up before 5 years, without rerecurrence having been diagnosed. Of the remaining 51 patients, one underwent...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1986-05-01 00:00:00
abstract::In recent years, much attention has been paid to the assessment of the quality of health care. This focus has been driven mainly by a desire to improve health care and decrease inequalities within health care systems. As well as addressing key areas such as structure, process, and outcome, which are normally taken fro...
journal_title:Surgery
pub_type: 杂志文章,评审
doi:10.1016/j.surg.2009.03.019
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:With over 110,000 bariatric operations performed in the United States annually, it is important to understand the biochemical abnormalities causing endocrine dysfunction associated with these procedures. Here we compare 2 malabsorptive procedures, duodenal switch and Roux-en-Y gastric bypass, to determine th...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2016.08.046
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:The Affordable Care Act aims to improve patient outcomes. Race/ethnicity and insurance status impact outcomes after traumatic brain injury. We sought to gauge the Affordable Care Act's effect on outcomes after traumatic brain injury, as graded by race/ethnicity and insurance status. METHODS:The National Tra...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2017.09.006
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Current isolation techniques recover only 20% to 50% of the pancreatic islets. Brain death (BD) is characterized by activation of proinflammatory cytokines (PICs) with reduced islet yields and functionality. We previously reported that 17beta-estradiol (E2) induces cytoprotection to human islets exposed to P...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2004.05.009
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND:Identification of recurrent laryngeal nerve (RLN) has decreased the rates of permanent RLN palsy during thyroid operations; however, unexpected RLN palsy still occurs, even though the visual integrity was assured and most nerve injuries were not recognized intraoperatively. The aim of this study is to determ...
journal_title:Surgery
pub_type: 临床试验,杂志文章
doi:10.1016/j.surg.2008.02.006
更新日期:2008-06-01 00:00:00
abstract:INTRODUCTION:Standard resection for benign and borderline neoplasms of the pancreas is associated with a substantial risk of postoperative morbidity and long-term functional impairment, whereas enucleation leads to less morbidity and preserves healthy parenchyma as well as pancreatic function. The aim of this study was...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2014.10.008
更新日期:2015-11-01 00:00:00
abstract::We have investigated the effect of bile on fat-stimulated release and basal plasma levels of cholecystokinin-33/39 (CCK) and neurotensin in six awake dogs prepared with chronic gastric and duodenal cannulas. Experimental bile diversion was achieved by catheterization of the common bile duct through the duodenal cannul...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1986-08-01 00:00:00
abstract:BACKGROUND:Mortality after acute respiratory distress syndrome is higher in males than in females. Gender differences in pulmonary vascular reactivity and local inflammatory response may explain this disparity. We hypothesized that endothelium-dependent pulmonary vasorelaxation is impaired in males and that this effect...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2005.03.002
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND:Central gastrectomy (CG) for gastric cancer was developed to preserve pyloric function and maintain a large gastric volume. Whether this procedure is feasible for limited cases of gastric cancer is unclear. METHODS:On the basis of Union Internationale Contre le Cancer TNM classification, pathologic characte...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1067/msy.2003.33
更新日期:2003-01-01 00:00:00
abstract::Hyperparathyroid crisis is a rare, life-threatening condition that requires prompt removal of the involved parathyroid gland(s). This report describes a patient with hyperparathyroid crisis caused by a mediastinal parathyroid adenoma, which was localized before operation and removed at the initial operation, without n...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1993-05-01 00:00:00
abstract:BACKGROUND:Regulation of coronary vasomotor tone by serotonin is significantly changed after cardioplegic arrest and reperfusion. The current study investigates whether cardiopulmonary bypass may also affect peripheral arteriolar response to serotonin in patients with or without diabetes. METHODS:Human peripheral micr...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2018.03.007
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:The aim of this study was to assess the risk of recurrent laryngeal nerve palsy (RLNP) after thyroidectomy with routine identification of the recurrent laryngeal nerve (RLN) during the operation. METHODS:The present study was confined to 521 patients, 348 total lobectomies and 178 total thyroidectomies, tre...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2004.09.008
更新日期:2005-03-01 00:00:00
abstract:INTRODUCTION:Policies that mandate colorectal screening coverage by private insurers are associated with increased use of screening procedures. We seek to understand whether such mandates have improved access to care and short-term operative outcomes for patients undergoing operations of the colon and rectum (OCR). ME...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2013.04.037
更新日期:2013-08-01 00:00:00
abstract::We reviewed 137 patients with colon injury and applied multiple regression analysis to determine the influence of various parameters on colon-related infection. The complications of intra-abdominal abscess, wound infection, and peristomal abscess occurred in 25% of patients. The mortality rate was 3.6%, and four of fi...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1986-10-01 00:00:00
abstract::In 112 patients with severe ischemia of the lower limb and without a suitable saphenous vein, 99 femoropopliteal and 22 femorodistal bypass procedures were performed with the modified human umbilical vein (Biograft, Meadox Medicals Inc., Oakland, N.J.). Seventy-eight percent of the operations were performed for limb s...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1985-03-01 00:00:00
abstract:BACKGROUND:To avoid the complications associated with overfeeding or underfeeding, the energy requirements of patients receiving total parenteral nutrition (TPN) must be accurately prescribed. However, until recently it has not been possible to directly measure the rates of total energy expenditure (TEE) in surgical pa...
journal_title:Surgery
pub_type: 临床试验,杂志文章
doi:10.1016/s0039-6060(05)80010-8
更新日期:1995-07-01 00:00:00
abstract::This study evaluates the effect of reverse electrical pacing on intestinal absorption and transit time in an enterostomy model. Twenty-five male Sprague-Dawley rats (148 to 208 gm) underwent division and anastomosis of the proximal jejunum to eliminate the proximal gastroduodenal pacemaker. A 30.0 cm loop ileostomy wa...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1986-08-01 00:00:00
abstract::One possible cause of pulmonary failure after trauma is the type of asanguinous fluid used for resuscitation, i.e., crystalloid or colloid. To investigate this issue, patients having a laparotomy for trauma randomly received either Ringer's lactate (RLS) alone or Ringer's lactate with albumin (ALB). Both groups receiv...
journal_title:Surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1977-06-01 00:00:00
abstract::Serial thickness measurements of the glomerular basement membrane were performed over a 24-month period in four groups of inbred male Lewis rats. Group I consisted of normal animals age-matched to the remaining experimental groups. In groups II, III, and IV, diabetes was induced by intravenous alloxan (42 to 44 mg/kg)...
journal_title:Surgery
pub_type: 杂志文章
doi:
更新日期:1980-07-01 00:00:00
abstract:BACKGROUND:Many postoperative concerns after common general operative procedures may be addressed over the phone, thereby saving time and resources for both the patient and surgeon. METHODS:Over a 6-month time period, patients who underwent laparoscopic cholecystectomy, appendectomy for uncomplicated appendicitis, and...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2013.05.005
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:As a measure of quality, ambulatory surgery centers have begun reporting rates of hospital transfer at discharge. This process, however, may underestimate the acute care needs of patients after care. We conducted this study to determine rates and evaluate variation in hospital transfer and hospital-based, ac...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2013.12.008
更新日期:2014-05-01 00:00:00