Abstract：
:Over a three year period, 28 children or young adults up to 20 years of age underwent 60 thoracotomies for pulmonary metastatic osteogenic sarcoma. These patients also received adjuvant chemotherapy. Sixteen of the 28 patients are currently alive and 13 of these are free of disease. The patients have been followed for 6 to 48 months after the initial thoracotomy; median survival is 25 months. Actuarial survival curves produced a 4 year survival of 57%. Although a tumor-free interval of more than 1 year greatly enhanced survival, three patients survived with tumor-free interval of 6 months or less. Patients with disease confined to one lobe at the initial thoracotomy did very well, and yet survivors were seen when disease involved more than one lobe or was bilateral. An aggressive surgical approach toward the pulmonary metastases thus appears to be justified.
journal_name
Surgeryjournal_title
Surgeryauthors
Telander RL,Pairolero PC,Pritchard DJ,Sim FH,Gilchrist GSsubject
Has Abstractpub_date
1978-09-01 00:00:00pages
335-41issue
3eissn
0039-6060issn
1532-7361journal_volume
84pub_type
杂志文章相关文献
SURGERY文献大全abstract：BACKGROUND:Apolipoprotein J (ApoJ) is expressed after vascular injury and remodeling and may inhibit endothelial cell activation in the vascular wall. Recently, ApoJ was identified as upregulated in hyperplastic lesions after prosthetic arterial grafting. This study analyzed the effect of ApoJ on human umbilical vein e...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1067/msy.2001.115823
更新日期：2001-08-01 00:00:00
abstract：BACKGROUND:Interleukin 12 (IL-12) p70 is a heterodimeric protein (p35, p40 subunits) that promotes T-helper TH1-type cytokine response. In critically ill patients, after severe trauma or sepsis, IL-12 production is markedly impaired. We tested the hypothesis that deficiency of the transcription factor c-fos will increa...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1999-08-01 00:00:00
abstract：BACKGROUND:Neointima formation after human saphenous vein grafting (hSVG) involves several matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs). This study assessed the feasibility of modulating MMP activity in hSVGs by adenovirus-mediated gene transfer. METHODS:First, 1 x 10(9) plaque-forming units (p...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1998-08-01 00:00:00
abstract：BACKGROUND:To determine whether the gene expression of both acute-phase reactants (APR) and the major heat-shock protein (hsp-72) can occur simultaneously, transcriptional rates were measured during shock and resuscitation. METHODS:A nuclear runoff technique was applied to hepatic biopsy specimens obtained from pigs b...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1992-08-01 00:00:00
abstract：:During a 3-year period (1984 through 1987), 40 patients with smoke inhalation, cutaneous burns, or a combination of both injuries were studied. Injuries were assigned to the three categories on the basis of bronchoscopic findings and clinical history. Eleven patients had simultaneously sustained a common smoke-inhalat...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1987-08-01 00:00:00
abstract：:In an effort to decrease the large number of patients who develop hypothyroidism after operations for Graves' disease, an identical modification of the conventional subtotal thyroidectomy (CST) was independently designed and tested in a prospective study at two institutions. The modified subtotal thyroidectomy (MST) e...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1983-12-01 00:00:00
abstract：:The term big data has been popularized over the past decade and is often used to refer to data sets that are too large or complex to be analyzed by traditional means. Although the term has been utilized for some time in business and engineering, the concept of big data is relatively new to medicine. The reception from...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2018.06.022
更新日期：2018-10-01 00:00:00
abstract：:Two patients with hepatorenal syndrome were treated by insertion of a peritoneovenous shunt. The renal deficit was corrected rapidly in both cases. A 62-year-old woman with a slow onset syndrome with urine output of 100 to 150 ml/day and urinary sodium excretion of 1 mEq/day responded with large volume urinary output ...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1977-09-01 00:00:00
abstract：:The experience with 14 patients with infected aortic bifurcation grafts has been reviewed. Factors which appeared to predispose to infection in 11 patients included "re-do" operations, concomitant cholecystectomy or gastrostomy, and ruptured abdominal aneurysm. A mixture of gastrointestinal organisms was responsible f...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1976-11-01 00:00:00
abstract：BACKGROUND:Operative resection is the only curative treatment for patients with pheochromocytomas, paragangliomas, and other catecholamine-producing neoplasms. Activation of glycogen synthase kinase 3beta (GSK3beta) is thought to promote tumor growth and neuroendocrine (NE) peptide secretion in NE neoplasms. Thus, we h...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2006.12.005
更新日期：2007-02-01 00:00:00
abstract：:In the past 11 years we have operated on three patients with "tiny" parathyroid adenomas (less than 60 mg). Two of these adenomas were virtually indistinguishable visually from the normal glands. (The third adenoma was found only after fixation and permanent sections.) Despite frozen-section diagnoses of "probable hyp...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1986-12-01 00:00:00
abstract：:Although well accepted in pediatric patients, nonoperative management of blunt hepatic trauma in adults remains controversial. From January 1981 through May 1987, 66 adults were identified with blunt hepatic trauma that had been confirmed by abdominal exploration or abdominal computed tomography (CT): 46 underwent imm...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1988-10-01 00:00:00
abstract：:In an experimental canine model of isolated and tandem arterial stenoses, noninvasive thigh and calf pressure measurements were evaluated against direct intra-arterial pressures. Under control circumstances, proximal iliac arterial stenosis, and high superficial femoral artery stenosis, the noninvasive measurements we...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1981-03-01 00:00:00
abstract：BACKGROUND:The purpose of this study was to define the redox sensitive cis-acting transcriptional mechanisms that regulate inducible nitric oxide synthase (iNOS) promoter function in the hepatocyte. METHODS:Clonal deletion constructs of the rat hepatocyte iNOS promoter (Genbank X95629; 1845 base pair)-reporter plasmid...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1999-08-01 00:00:00
abstract：:Two granular cell tumors of the biliary tree are described, one in a 37-year-old black woman with obstructive jaundice and the other in a 26-year-old white woman with abdominal pain. These are rare soft tissue tumors that have an excellent prognosis when surgically excised. Almost all reported cases have been in young...
journal_title：Surgery
pub_type： 杂志文章,评审
doi：
更新日期：1988-03-01 00:00:00
abstract：BACKGROUND:Muscle protein catabolism, reflected by a decrease in glutamine (GLN), a decrease in muscle protein synthesis, and a negative nitrogen balance can be reduced by either administration of GLN or growth hormone (GH). In this study, the effects of a combination of GH and GLH were studied. METHODS:Patients (n = ...
journal_title：Surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1067/msy.2001.112593
更新日期：2001-05-01 00:00:00
abstract：BACKGROUND:Vocal cord paralysis is associated with extrathyroidal invasive malignancy. This study was performed to analyze the presentation of patients with invasive thyroid malignancy and to determine the preoperative symptomatic and radiographic correlates of vocal cord paralysis. METHODS:In a group of 365 consecuti...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2005.08.009
更新日期：2006-03-01 00:00:00
abstract：BACKGROUND:Recurrent acute pancreatitis often leads to chronic obstructive ductal disease requiring operative decompression. METHODS:From 1983 through 1998, 124 patients with ductal obstruction underwent lateral pancreaticojejunostomy (78 patients), distal pancreatectomy with end-to-side pancreaticojejunostomy (27 pat...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1999-10-01 00:00:00
abstract：BACKGROUND:Retroperitoneal sarcomas are rare tumors that can be locally aggressive with high rates of recurrence. Given that data on survival in patients with retroperitoneal sarcomas are conflicting, we sought to use a nationwide cancer database to identify factors associated with survival in patients with retroperito...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2016.05.041
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Major operative injury initiates immunologic changes that may result in a systemic inflammatory response, leading to organ dysfunction/sepsis. Catecholamines seem to be key mediators. The effects of beta(2) receptor blockade in vitro and in vivo before and after operative injury were studied to clarify their...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2008.09.013
更新日期：2009-02-01 00:00:00
abstract：:The emergence of both absorbable and nonabsorbable synthetic materials has been primary among the many new developments in suture materials. This is a study of 16 types of natural and synthetic suture materials and their resistance to both gram-positive and gram-negative infections. Four hundred and twenty suture inpl...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：BACKGROUND:It is well recognized that hypoxia/reoxygenation and exposure to inflammatory mediators such as cytokines and neutrophils alter the barrier function of the vascular endothelium. The experiments we conducted tested whether hypoxia alone could produce changes in permeability and whether a prolonged period of h...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1998-09-01 00:00:00
abstract：BACKGROUND:Outcomes of bariatric surgery in patients with a body mass index (BMI) <35 kg/m(2) have been an active area of investigation. We examined the comparative effectiveness of Roux-en-Y gastric bypass (RYGB) to routine medical management (nonsurgical controls; NSCs) in achieving appropriate targets defined by the...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2011.07.069
更新日期：2011-10-01 00:00:00
abstract：BACKGROUND:Although various suture techniques for murine pancreas transplantation have been described, severe limitations have limited their widespread use. We therefore designed a surgical model for cervical heterotopic pancreas transplantation using a cuff technique. METHODS:C57BL6 mice were used as donor and recipi...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2006.07.037
更新日期：2007-05-01 00:00:00
abstract：BACKGROUND:In clinically node-negative patients with differentiated thyroid cancer (DTC), indications for routine central lymph node dissection (RCLD) are the subject of intensive research, and surgeons are divided between the pros and cons of this surgery. To better define the role of neck dissection in the treatment ...
journal_title：Surgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.surg.2014.02.010
更新日期：2014-06-01 00:00:00
abstract：BACKGROUND:Although portal venous tumor thrombus (PVTT) is regarded as an ominous prognostic factor in patients with hepatocellular carcinoma (HCC), the optimal treatment method for maximizing both safety and long-term outcome has not yet been discussed. We describe a surgical technique in which the venous wall is peel...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2008.09.005
更新日期：2009-01-01 00:00:00
abstract：:For the surgeon, atherosclerosis is defined by a variety of aneurysmal, occlusive, or ulcerated lesions in major arteries. These end-stage lesions often require operative treatment. However, just as advanced atherosclerosis presents complex clinical phenomena, so its earlier stages display many underlying mechanisms p...
journal_title：Surgery
pub_type： 杂志文章,评审
doi：
更新日期：1978-08-01 00:00:00
abstract：BACKGROUND:Estimates of the number of firearm-related injuries widely vary. Although focus has been primarily on deaths, the societal cost of caring for victims of these injuries is largely unknown. Our goal was to estimate the economic impact of nonfatal, firearm-related injuries in the United States based on recent, ...
journal_title：Surgery
pub_type： 杂志文章
doi：10.1016/j.surg.2014.02.011
更新日期：2014-05-01 00:00:00
abstract：:Prevention of ischemic bowel complications following abdominal aortic reconstruction requires identification of the patient at high risk for developing the complication; on precise, gentle, meticulous operative technique; on knowledge of bowel blood supply; on determining when the IMA must be reconstructed or when it ...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:Ten cases of vascular compression of the duodenum are presented, and 125 cases in the literature since 1962 are reviewed. More common in women than in men, the lesion may result from supine immobilization, wearing body cast, or a rapid weight loss. In about one third of the patients, no predisposing factor can be foun...
journal_title：Surgery
pub_type： 杂志文章
doi：
更新日期：1976-05-01 00:00:00
