Lumbrical sparing in carpal tunnel syndrome: anatomic, physiologic, and diagnostic implications.

Abstract:

:Motor axons supplying lumbrical muscles are less severely affected than axons supplying thenar muscles in the carpal tunnel syndrome; sometimes lumbrical motor fibers are less affected than digit 2 sensory fibers. This pattern is consistent with compression of both the anterior and posterior aspects of the median nerve in the carpal tunnel because nerve fibers responsible for thenar, lumbrical, and digit 2 functions lie in an anterior-posterior gradient within the distal median nerve. Recognition of lumbrical sparing supports the electrodiagnosis of carpal tunnel syndrome when the distal latency to thenar muscles or the palm-to-wrist mixed median nerve conduction velocity is normal.

journal_name

Neurology

journal_title

Neurology

authors

Logigian EL,Busis NA,Berger AR,Bruyninckx F,Khalil N,Shahani BT,Young RR

doi

10.1212/wnl.37.9.1499

subject

Has Abstract

pub_date

1987-09-01 00:00:00

pages

1499-505

issue

9

eissn

0028-3878

issn

1526-632X

journal_volume

37

pub_type

杂志文章
  • Subacute, reversible motor neuron disease.

    abstract::Four patients with a clinical syndrome closely resembling amyotrophic lateral sclerosis recovered completely, without treatment, 5 to 12 months after onset. Electrodiagnostic tests revealed acute and chronic denervation, with normal motor and sensory nerve conduction studies. The CSF was normal, and tests for paraprot...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.41.10.1541

    authors: Tucker T,Layzer RB,Miller RG,Chad D

    更新日期:1991-10-01 00:00:00

  • Serum creatine phosphokinase and pyruvate kinase in neuromuscular disorders and Duchenne dystrophy carriers.

    abstract::Serum levels of creatine phosphokinase (CPK) and pyruvic kinase (PK) were determined in 42 controls, 57 patients with various neuromuscular disorders, and 23 female relatives of Duchenne dystrophy patients. CPK and PK enzyme activities were increased in comparable numbers of muscle disease patients and female carriers...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.28.10.1047

    authors: Seay AR,Ziter FA,Wu LH,Wu JT

    更新日期:1978-10-01 00:00:00

  • Conjugal amyotrophic lateral sclerosis: report of a young married couple.

    abstract::We report a 38-year-old nurse who developed amyotrophic lateral sclerosis (ALS) beginning in September 1990. In May 1991, her 38-year-old husband developed dysarthria, which progressed to typical ALS. This is the fourth report in the literature of conjugal ALS occurring outside of Guam. Although this event is most lik...

    journal_title:Neurology

    pub_type: 杂志文章,评审

    doi:10.1212/wnl.43.11.2378

    authors: Cornblath DR,Kurland LT,Boylan KB,Morrison L,Radhakrishnan K,Montgomery M

    更新日期:1993-11-01 00:00:00

  • Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease.

    abstract:BACKGROUND:Treatment with 3-hydroxy-3-methylglutaryl-coenzyme-A reductase inhibitors ("statins") has been associated in some epidemiologic studies with reduced risk of Alzheimer disease (AD). However, direct evidence of statin effects on neuropathologic markers of AD is lacking. We investigated whether antecedent stati...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000277657.95487.1c

    authors: Li G,Larson EB,Sonnen JA,Shofer JB,Petrie EC,Schantz A,Peskind ER,Raskind MA,Breitner JC,Montine TJ

    更新日期:2007-08-28 00:00:00

  • A human brain network derived from coma-causing brainstem lesions.

    abstract:OBJECTIVE:To characterize a brainstem location specific to coma-causing lesions, and its functional connectivity network. METHODS:We compared 12 coma-causing brainstem lesions to 24 control brainstem lesions using voxel-based lesion-symptom mapping in a case-control design to identify a site significantly associated w...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000003404

    authors: Fischer DB,Boes AD,Demertzi A,Evrard HC,Laureys S,Edlow BL,Liu H,Saper CB,Pascual-Leone A,Fox MD,Geerling JC

    更新日期:2016-12-06 00:00:00

  • Linking MRI to daily life experience: the example of poststroke depression.

    abstract:OBJECTIVE:The state-of-the-art tools of neurology, in particular modern neuroimaging techniques, have yet to benefit from the revolution in mobile technologies that provide new insights into the mechanisms underlying clinical syndromes. This study demonstrates the manner in which mobile technologies may provide informa...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e31824528b2

    authors: Lassalle-Lagadec S,Allard M,Dilharreguy B,Schweitzer P,Swendsen J,Sibon I

    更新日期:2012-01-31 00:00:00

  • Effects of statins on human cerebral cholesterol metabolism and secretion of Alzheimer amyloid peptide.

    abstract::Cerebral cholesterol metabolism has been linked with production of amyloid peptide (Abeta) crucial in AD. The association between use of cholesterol-lowering drugs (statins) and AD disease is currently being intensely discussed. In this case-control study on elderly nondemented subjects, the authors provide the first ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.59.8.1257

    authors: Fassbender K,Stroick M,Bertsch T,Ragoschke A,Kuehl S,Walter S,Walter J,Brechtel K,Muehlhauser F,Von Bergmann K,Lütjohann D

    更新日期:2002-10-22 00:00:00

  • IgG receptor IIa alleles determine susceptibility and severity of Guillain-Barré syndrome.

    abstract:OBJECTIVE:Guillain-Barré syndrome (GBS) is characterized by nerve infiltration of leukocytes and autoantibodies of the immunoglobulin G (IgG) isotype directed against nerve constituents. Leukocyte receptors for IgG (FcgammaR) constitute an important link between the humoral and cellular parts of the immune system and c...

    journal_title:Neurology

    pub_type: 临床试验,杂志文章

    doi:10.1212/wnl.54.8.1661

    authors: van der Pol WL,van den Berg LH,Scheepers RH,van der Bom JG,van Doorn PA,van Koningsveld R,van den Broek MC,Wokke JH,van de Winkel JG

    更新日期:2000-04-25 00:00:00

  • Neurofilament protein levels in CSF are increased in dementia.

    abstract::The neurofilament is the major cytoskeletal structure of myelinated axons. In this study, CSF levels of the light subunit of the neurofilament protein (NFL) were increased in patients with vascular dementia (VAD), AD, and frontotemporal dementia (FTD) compared with neurologically healthy individuals. Because NFL is lo...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.52.5.1090

    authors: Rosengren LE,Karlsson JE,Sjögren M,Blennow K,Wallin A

    更新日期:1999-03-23 00:00:00

  • MRI correlates of neurofibrillary tangle pathology at autopsy: a voxel-based morphometry study.

    abstract:BACKGROUND:Neurofibrillary tangles (NFTs), composed of hyperphosphorylated tau proteins, are one of the pathologic hallmarks of Alzheimer disease (AD). We aimed to determine whether patterns of gray matter atrophy from antemortem MRI correlate with Braak staging of NFT pathology. METHODS:Eighty-three subjects with Bra...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000324924.91351.7d

    authors: Whitwell JL,Josephs KA,Murray ME,Kantarci K,Przybelski SA,Weigand SD,Vemuri P,Senjem ML,Parisi JE,Knopman DS,Boeve BF,Petersen RC,Dickson DW,Jack CR Jr

    更新日期:2008-09-02 00:00:00

  • Gamma-hydroxybutyrate in experimental myoclonus.

    abstract::In Swiss mice, muscimol (3 mg per kilogram, intraperitoneally) caused myoclonic jerks of the hindquarters. These jerks were strong, repetitive, more or less regular, and of high frequency (peak response, 76 per minute). Pretreatment with sodium gamma-hydroxybutyrate (50 to 200 mg per kilogram) caused a dose-dependent ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.32.4.434

    authors: Menon MK

    更新日期:1982-04-01 00:00:00

  • Racial differences in statin adherence following hospital discharge for ischemic stroke.

    abstract:OBJECTIVE:To compare nonadherence to statins in older black and white adults following an ischemic stroke. METHODS:We studied black and white adults ≥66 years of age with Medicare fee-for-service insurance coverage hospitalized for ischemic stroke from 2007 to 2012 who filled a statin prescription within 30 days follo...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000003910

    authors: Albright KC,Zhao H,Blackburn J,Limdi NA,Beasley TM,Howard G,Bittner V,Howard VJ,Muntner P

    更新日期:2017-05-09 00:00:00

  • Recovery of behavioral abnormalities after right hemisphere stroke.

    abstract::We studied recovery of function in 41 patients with right hemisphere stroke. Recovery was rapid for left neglect, prosopagnosia, anosognosia, and unilateral spatial neglect on drawing (USN). Recovery was slower for h mianopia, hemiparesis, motor impersistence, and extinction. Rates of recovery were intermediate for co...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.33.3.345

    authors: Hier DB,Mondlock J,Caplan LR

    更新日期:1983-03-01 00:00:00

  • Treatment of inclusion-body myositis with high-dose intravenous immunoglobulin.

    abstract::We report the treatment of four patients with inclusion-body myositis (IBM) and severe slowly progressive weakness using high-dose intravenous immunoglobulin (IVIg). After two monthly infusions, the strength of the proximal and less atrophic muscle groups improved or normalized in three of the four patients. The impro...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.43.5.876

    authors: Soueidan SA,Dalakas MC

    更新日期:1993-05-01 00:00:00

  • Epilepsy in the nevoid basal-cell carcinoma syndrome (Gorlin syndrome): report of a case due to a focal neuronal heterotopia.

    abstract::We present a case of uncontrolled temporal lobe epilepsy due to a focal left temporal neuronal heterotopia associated with the nevoid-basal-cell carcinoma syndrome. This is the first pathologically described lesion associated with temporal lobe epilepsy in this syndrome. Because the patient's seizures resolved after a...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.46.2.574

    authors: Hogan RE,Tress B,Gonzales MF,King JO,Cook MJ

    更新日期:1996-02-01 00:00:00

  • Prevalence of repetitive and reward-seeking behaviors in Parkinson disease.

    abstract::We surveyed 297 patients with Parkinson disease (PD) with systematic screens and rigorous definitional criteria. Pathologic hypersexuality lifetime prevalence was 2.4%. Compulsive shopping was 0.7%. Combined with our pathologic gambling data, the lifetime prevalence of these behaviors was 6.1% and increases to 13.7% i...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000238503.20816.13

    authors: Voon V,Hassan K,Zurowski M,de Souza M,Thomsen T,Fox S,Lang AE,Miyasaki J

    更新日期:2006-10-10 00:00:00

  • CNS neutrophilic vasculitis in neuro-Sweet disease.

    abstract::In the Clinical/Scientific Note “CNS neutrophilic vasculitis in neuro-Sweet disease” by R. Charlson et al. (Neurology® 2015;85:829–830), there is an error in the discussion and the references. The last name of the first author of reference 2 should be Hisanaga, not Hisanga as originally published. The authors regret t...

    journal_title:Neurology

    pub_type: 已发布勘误

    doi:10.1212/WNL.0000000000002139

    authors:

    更新日期:2015-11-17 00:00:00

  • Serum folate and chronic fatigue syndrome.

    abstract::We assayed serum folate levels of 60 patients with chronic fatigue syndrome (CFS) and found that 50% had values below 3.0 micrograms/l. Some patients with CFS are deficient in folic acid. ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.43.12.2645

    authors: Jacobson W,Saich T,Borysiewicz LK,Behan WM,Behan PO,Wreghitt TG

    更新日期:1993-12-01 00:00:00

  • Juvenile-onset glycogen storage disease type II with novel mutations in acid alpha-glucosidase gene.

    abstract::The authors describe two novel mutations of the acid alpha-glucosidase gene, P361L and R437C, which define the juvenile-onset glycogen storage disease type II (GSDII) in a 16-year-old Chinese patient. The asymptomatic 13-year-old brother of the proband is also a compound heterozygote of the two mutations. These result...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000048661.95327.bf

    authors: Lam CW,Yuen YP,Chan KY,Tong SF,Lai CK,Chow TC,Lee KC,Chan YW,Martiniuk F

    更新日期:2003-02-25 00:00:00

  • Severity of REM atonia loss in idiopathic REM sleep behavior disorder predicts Parkinson disease.

    abstract:BACKGROUND:Over 50% of persons with idiopathic REM sleep behavior disorder (RBD) will develop Parkinson disease (PD) or dementia. At present, there is no way to predict who will develop disease. Since polysomnography is performed in all patients with idiopathic RBD at diagnosis, there is an opportunity to analyze if ba...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e3181ca0166

    authors: Postuma RB,Gagnon JF,Rompré S,Montplaisir JY

    更新日期:2010-01-19 00:00:00

  • Cerebrovascular perfusion in marijuana users during a month of monitored abstinence.

    abstract:OBJECTIVE:To determine possible effects of prolonged marijuana use on the cerebrovascular system during a month of monitored abstinence and to assess how the intensity of current use might have influenced cerebrovascular perfusion in these marijuana users. METHOD:The authors recorded blood flow velocity in the anterio...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.WNL.0000150882.69371.DD

    authors: Herning RI,Better WE,Tate K,Cadet JL

    更新日期:2005-02-08 00:00:00

  • Earlier is better: the benefits of early diagnosis.

    abstract::The concept of earlier diagnosis of amyotrophic lateral sclerosis (ALS) requires in-depth investigation of its benefits and consequences. First, how good must a treatment be before ALS is determined to be a treatable condition? Analogy with cancer therapy suggests that a good quality of life after treatment is an esse...

    journal_title:Neurology

    pub_type: 杂志文章,评审

    doi:

    authors: Brooks BR

    更新日期:1999-01-01 00:00:00

  • Cerebellar learning distinguishes inflammatory neuropathy with and without tremor.

    abstract:OBJECTIVES:This study aims to investigate if patients with inflammatory neuropathies and tremor have evidence of dysfunction in the cerebellum and interactions in sensorimotor cortex compared to nontremulous patients and healthy controls. METHODS:A prospective data collection study investigating patients with inflamma...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e318292a2b8

    authors: Schwingenschuh P,Saifee TA,Katschnig-Winter P,Reilly MM,Lunn MP,Manji H,Aguirregomozcorta M,Schmidt R,Bhatia KP,Rothwell JC,Edwards MJ

    更新日期:2013-05-14 00:00:00

  • Estrogen treatment of dyskinetic disorders.

    abstract::Estrogen have been reported in animal studies to both enhance and block central dopaminergic activity and in one clinical report to improve tardive dyskinesia. In the present study estrogen (Premarin, 2.5 mg per day) administration caused varying degrees of improvement in less than one-third of 21 patients with chorea...

    journal_title:Neurology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1212/wnl.32.5.547

    authors: Koller WC,Barr A,Biary N

    更新日期:1982-05-01 00:00:00

  • History of head trauma and risk of intracranial meningioma: population-based case-control study.

    abstract::A population-based case-control study in western Washington state was performed to assess the relation between head trauma and meningioma. Based on 200 case and 400 control subjects, head trauma was associated with an increased risk of meningioma (odds ratio = 1.83; 95% CI = 1.28, 2.62), especially head traumas occurr...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.58.12.1849

    authors: Phillips LE,Koepsell TD,van Belle G,Kukull WA,Gehrels JA,Longstreth WT Jr

    更新日期:2002-06-25 00:00:00

  • Amyotrophic lateral sclerosis: thyrotropin-releasing hormone and histidyl proline diketopiperazine in the spinal cord and cerebrospinal fluid.

    abstract::In spinal cords from seven amyotrophic lateral sclerosis (ALS) patients and four controls, we found no difference in thyrotropin-releasing hormone (TRH) concentration relative to protein content, but there was a reduction per tissue wet weight in ALS. Immunohistochemical localization of TRH in ALS cord was unaltered. ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.36.9.1218

    authors: Jackson IM,Adelman LS,Munsat TL,Forte S,Lechan RM

    更新日期:1986-09-01 00:00:00

  • Adult-onset leukoencephalopathy with vanishing white matter with a missense mutation in EIF2B5.

    abstract::We report of a woman aged 52 years born to consanguineous parents and seeking treatment for progressive dementia and delusion. Neurologic examination revealed dementia and emotional instability, indifference, and confabulation. There was also mild spasticity of the bilateral lower limbs. MRI revealed diffuse white mat...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000123117.11264.0e

    authors: Ohtake H,Shimohata T,Terajima K,Kimura T,Jo R,Kaseda R,Iizuka O,Takano M,Akaiwa Y,Goto H,Kobayashi H,Sugai T,Muratake T,Hosoki T,Shioiri T,Okamoto K,Onodera O,Tanaka K,Someya T,Nakada T,Tsuji S

    更新日期:2004-05-11 00:00:00

  • Familial frontotemporal dementia with ubiquitin-positive, tau-negative inclusions.

    abstract:OBJECTIVE:To describe the clinical features, neuropathology, and genetic studies in a family with autosomal dominant frontotemporal dementia (FTD). BACKGROUND:Clinical Pick's disease, or FTD with parkinsonism, has been described in several families linked to chromosome 17 (FTDP-17). Most of these have shown tau protei...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.54.4.818

    authors: Kertesz A,Kawarai T,Rogaeva E,St George-Hyslop P,Poorkaj P,Bird TD,Munoz DG

    更新日期:2000-02-22 00:00:00

  • Neurofilament and glial fibrillary acidic protein in multiple sclerosis.

    abstract:OBJECTIVE:To evaluate levels of neurofilament light (NFL) and glial fibrillary acidic protein (GFAP) in CSF from patients with multiple sclerosis (MS) in relation to clinical progress of the disease. METHODS:CSF levels of NFL and GFAP were determined by sensitive ELISAs in 99 patients with different subtypes of MS, cl...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000142988.49341.d1

    authors: Norgren N,Sundström P,Svenningsson A,Rosengren L,Stigbrand T,Gunnarsson M

    更新日期:2004-11-09 00:00:00

  • Tobacco smoking and the risk of Parkinson disease: A 65-year follow-up of 30,000 male British doctors.

    abstract:OBJECTIVE:To investigate the causal relevance of current tobacco smoking for the risk of Parkinson disease (PD). METHODS:We compared the risks of death from PD with smoking habits in 30,000 male doctors in the British Doctors cohort study in 1951 and in survivors who had been resurveyed periodically for 5 decades. Cau...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000009437

    authors: Mappin-Kasirer B,Pan H,Lewington S,Kizza J,Gray R,Clarke R,Peto R

    更新日期:2020-05-19 00:00:00