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1,3,4-Thiadiazoles: a potent multi targeted pharmacological scaffold.

Abstract：

:Despite a significant work on thiadiazoles, continuous efforts are still being made to identify novel heterocyclic compounds with potent biological activities. This review may help the medicinal chemists to develop new leads possessing 1,3,4-thiadiazole nucleus with higher efficacy and reduced side effects. This review throws light on the detailed synthetic approaches which have been used for the synthesis of thiadiazoles. This has been followed by the in depth analysis of the thiadiazoles with respect to their medicinal significance.

journal_name

Eur J Med Chem

journal_title

European journal of medicinal chemistry

authors

Haider S,Alam MS,Hamid H

doi

10.1016/j.ejmech.2014.12.035

subject

Has Abstract

pub_date

2015-03-06 00:00:00

pages

156-77

eissn

0223-5234

issn

1768-3254

pii

S0223-5234(14)01144-1

journal_volume

92

pub_type

杂志文章,评审

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