Forebrain monoamines and associative learning: III. The US pre-exposure effect.

Abstract:

:This experiment evaluated the effects of forebrain norepinephrine (NE) and serotonin depletion on the unconditioned stimulus (US) pre-exposure phenomenon. Rats with either dorsal bundle lesions, raphe lesions, or which served as vehicle controls were assigned to one of two training conditions. One-half of the animals in the 3 lesion groups received 30 episodes of a stimulus which later served as the US. The remaining rats experienced standard conditioning of CS-US pairing without US pre-exposure. The results indicate that while raphe-lesioned and vehicular rats exhibited the US pre-exposure effect, conditioning was unimpaired in NE-depleted rats following pre-exposure. These findings are consistent with a contextual blocking interpretation of the US pre-exposure effect.

journal_name

Behav Brain Res

authors

Rickert EJ,Lorden JF

doi

10.1016/s0166-4328(89)80115-9

subject

Has Abstract

pub_date

1989-11-01 00:00:00

pages

147-52

issue

2

eissn

0166-4328

issn

1872-7549

pii

S0166-4328(89)80115-9

journal_volume

35

pub_type

杂志文章
  • Effects of an early postnatal hypoxia on the development of spontaneous head movements in rabbits.

    abstract::The early detection of minor brain dysfunctions resulting from perinatal hypoxia is very important since the prognosis of the affected children can be substantially improved by a prompt treatment. Therefore, this paper deals with the influence of an early postnatal hypoxia on the postnatal development of spontaneous h...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/0166-4328(93)90148-j

    authors: Woldag H,Tegetmeyer H

    更新日期:1993-12-31 00:00:00

  • Valproic acid effects in the hippocampus and prefrontal cortex in an animal model of post-traumatic stress disorder.

    abstract::Reactive oxygen species (ROS) and pro-inflammatory cytokines (PIC) are upregulated in post-traumatic stress disorder (PTSD). Histone deacetylase inhibitors (HDACi) modify genetic transcription and can diminish ROS and PIC escalation. They can also modulate levels of neurotransmitters such as catecholamines and seroton...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2014.03.029

    authors: Wilson CB,McLaughlin LD,Ebenezer PJ,Nair AR,Francis J

    更新日期:2014-07-15 00:00:00

  • Perinatal flutamide and mounting and lordosis behavior in adult female Wistar and Sprague-Dawley rats.

    abstract::The present study was designed to investigate the possible role of perinatal androgens acting via the androgen receptor, as opposed to the estrogen receptor, for the differentiation of adult mounting and lordosis behavior in female rats. Female Wistar (W) and Sprague-Dawley (SD) rats were exposed to the anti-androgen ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/s0166-4328(05)80238-4

    authors: Brand T,Slob AK

    更新日期:1991-07-01 00:00:00

  • Preferential looking acuity in preterm infants.

    abstract::Acuity was measured in 48 prematurely born infants using the preferential looking technique. These quantitative results show that acuity development in these infants is related to conceptional rather than postnatal age, in agreement with the qualitative findings of previous studies. Severe intraventricular haemorrhage...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/0166-4328(83)90149-3

    authors: Van Hof-van Duin J,Mohn G,Fetter WP,Mettau JW,Baerts W

    更新日期:1983-10-01 00:00:00

  • Dynamic task observation: A gaze-mediated complement to traditional action observation treatment?

    abstract::Action observation elicits changes in primary motor cortex known as motor resonance, a phenomenon thought to underpin several functions, including our ability to understand and imitate others' actions. Motor resonance is modulated not only by the observer's motor expertise, but also their gaze behaviour. The aim of th...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2019.112351

    authors: D'Innocenzo G,Nowicky AV,Bishop DT

    更新日期:2020-02-03 00:00:00

  • Paw preference in dogs: relations between lateralised behaviour and immunity.

    abstract::Paw use in a task consisting of the removal of a piece of adhesive paper from the snout was investigated in 80 mongrel and pure-bred domestic dogs (Canis familiaris). Population lateralisation was observed, but in opposite directions in the two sexes (animals were not desexed): males preferentially used their left paw...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2004.01.009

    authors: Quaranta A,Siniscalchi M,Frate A,Vallortigara G

    更新日期:2004-08-31 00:00:00

  • The underestimated role of olfaction in avian reproduction?

    abstract::Until the second half of the 20th century, it was broadly accepted that most birds are microsmatic if not anosmic and unable to detect and use olfactory information. Exceptions were eventually conceded for species like procellariiforms, vultures or kiwis that detect their food at least in part based on olfactory signa...

    journal_title:Behavioural brain research

    pub_type: 杂志文章,评审

    doi:10.1016/j.bbr.2008.08.036

    authors: Balthazart J,Taziaux M

    更新日期:2009-06-25 00:00:00

  • Mammary olfactory signalisation in females and odor processing in neonates: ways evolved by rabbits and humans.

    abstract::Mammalian females have long been known to release olfactory attraction in their offspring. Mammary odor cues control infant state, attention and directional responses, delay distress responses, stimulate breathing and positive oral actions, and finally can boost learning. Here, we survey female-offspring odor communic...

    journal_title:Behavioural brain research

    pub_type: 杂志文章,评审

    doi:10.1016/j.bbr.2009.02.008

    authors: Schaal B,Coureaud G,Doucet S,Delaunay-El Allam M,Moncomble AS,Montigny D,Patris B,Holley A

    更新日期:2009-06-25 00:00:00

  • Homing behavior of hippocampus and parahippocampus lesioned pigeons following short-distance releases.

    abstract::The avian hippocampal formation has been proposed to play a critical role in the neural regulation of a navigational system used by homing pigeons to locate their loft once in the familiar area near home. In support of this hypothesis, the homing performance of pigeons with target lesions of either the hippocampus or ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/0166-4328(90)90079-t

    authors: Bingman VP,Mench JA

    更新日期:1990-11-30 00:00:00

  • Different systems in the posterior hypothalamic nucleus of rats control theta frequency and trigger movement.

    abstract::Reduced frequency of theta activity is thought to compromise hippocampal function and so behavioural inhibition. The anxiolytic benzodiazepine chlordiazepoxide (CDP) reduces theta frequency when injected into the medial supramammillary nucleus (mSuM), posterior hypothalamic nucleus (PH) and dorsomedial hypothalamic nu...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2005.04.004

    authors: Woodnorth MA,McNaughton N

    更新日期:2005-08-30 00:00:00

  • Alterations in cognitive function in prepubertal mice with protein malnutrition: relationship to changes in choline acetyltransferase.

    abstract::We have found that protein malnutrition (PM) causes a significant impairment of memory-related behavior on the 15th and 20th day after the start of PM (5% casein) feeding in prepubertal mice but not in postpubertal mice, as measured by a passive-avoidance task. This impairment was almost completely reversed by merely ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2005.08.024

    authors: Nakagawasai O,Yamadera F,Sato S,Taniguchi R,Hiraga H,Arai Y,Murakami H,Mawatari K,Niijima F,Tan-No K,Tadano T

    更新日期:2006-02-15 00:00:00

  • Human avoidance and approach learning: evidence for overlapping neural systems and experiential avoidance modulation of avoidance neurocircuitry.

    abstract::Adaptive functioning is thought to reflect a balance between approach and avoidance neural systems with imbalances often producing pathological forms of avoidance. Yet little evidence is available in healthy adults demonstrating a balance between approach and avoidance neural systems and modulation in avoidance neuroc...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2011.07.054

    authors: Schlund MW,Magee S,Hudgins CD

    更新日期:2011-12-01 00:00:00

  • Dendritic morphology of amygdala and hippocampal neurons in more and less predator stress responsive rats and more and less spontaneously anxious handled controls.

    abstract::We investigated the neurobiological bases of variation in response to predator stress (PS). Sixteen days after treatment (PS or handling), rats were grouped according to anxiety in the elevated plus maze (EPM). Acoustic startle was also measured. We examined the structure of dendritic trees of basolateral amygdala (BL...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2011.09.009

    authors: Adamec R,Hebert M,Blundell J,Mervis RF

    更新日期:2012-01-01 00:00:00

  • Effects of antihypertensive drugs on ultrasound production and cardiovascular responses in 15-day-old rats.

    abstract::When exposed to extreme cold or injected with the alpha(2)-adrenoceptor agonist, clonidine, infant rats emit ultrasonic vocalizations (USVs). Based upon the cardiovascular changes that accompany these two manipulations, especially decreased venous return, it was hypothesized that USVs are the acoustic by-product of th...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/s0166-4328(01)00369-2

    authors: Blumberg MS,Sokoloff G,Kirby RF,Knoot TG,Lewis SJ

    更新日期:2002-04-01 00:00:00

  • Immune activation during mid-gestation disrupts sensorimotor gating in rat offspring.

    abstract::Maternal immune activation (MIA) is a newly developed animal model of schizophrenia. It has recently been reported that when MIA is induced with the cytokine inducer polyinosinic-polycytidilic acid (poly I:C) rats do not show deficits in prepulse inhibition (PPI), a test that is often considered a validity benchmark. ...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2008.02.021

    authors: Wolff AR,Bilkey DK

    更新日期:2008-06-26 00:00:00

  • Cannabidiol attenuates haloperidol-induced catalepsy and c-Fos protein expression in the dorsolateral striatum via 5-HT1A receptors in mice.

    abstract::Cannabidiol (CBD) is a major non-psychoactive compound from Cannabis sativa plant. Given that CBD reduces psychotic symptoms without inducing extrapyramidal motor side-effects in animal models and schizophrenia patients, it has been proposed to act as an atypical antipsychotic. In addition, CBD reduced catalepsy induc...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2016.04.042

    authors: Sonego AB,Gomes FV,Del Bel EA,Guimaraes FS

    更新日期:2016-08-01 00:00:00

  • Effect of disconnecting the orbital prefrontal cortex from the nucleus accumbens core on inter-temporal choice behaviour: a quantitative analysis.

    abstract::Previous experiments showed that destruction of the orbital prefrontal cortex (OPFC) or the nucleus accumbens core (AcbC) in rats altered choice between two delayed food reinforcers. Application of a quantitative model of inter-temporal choice suggested that lesions of either structure increased the delay-dependent de...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2008.03.041

    authors: Bezzina G,Body S,Cheung TH,Hampson CL,Bradshaw CM,Szabadi E,Anderson IM,Deakin JF

    更新日期:2008-08-22 00:00:00

  • Differences in extinction of conditioned fear in C57BL/6 substrains are unrelated to expression of alpha-synuclein.

    abstract::C57BL/6 mice are commonly used as background strains for genetically modified mice, and little attention is usually paid to the notification of the specific substrain. However, it is known that C57BL/6NCrl (B6N) and C57BL/6JOlaHsd (B6JOla) mice differ in the course of extinction of conditioned fear (Stiedl O, Radulovi...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2004.07.007

    authors: Siegmund A,Langnaese K,Wotjak CT

    更新日期:2005-02-28 00:00:00

  • The effects of the intraamygdalar melatonin injections on the anxiety like behavior and the spatial memory performance in male Wistar rats.

    abstract::In the present study, the effects of intraamygdalar administrations of melatonin (1 and 100μg/kg), saline and diazepam on the anxiety-like behavior and spatial memory performance in pinealectomized and sham-pinealectomized Wistar rats were investigated. The animals were tested by open field and elevated plus maze test...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2011.03.029

    authors: Karakaş A,Coşkun H,Kaya A,Kücük A,Gündüz B

    更新日期:2011-09-12 00:00:00

  • Training-induced structural changes in the adult human brain.

    abstract::Structural and functional brain reorganisation can occur beyond the developmental maturation period and this was recently recognised as an intrinsic property of the human central nervous system. Brain injury or altered afferent input due to environmental changes, novel experience and learning new skills are known as m...

    journal_title:Behavioural brain research

    pub_type: 杂志文章,评审

    doi:10.1016/j.bbr.2008.02.015

    authors: Draganski B,May A

    更新日期:2008-09-01 00:00:00

  • Celecoxib delays cognitive decline in an animal model of neurodegeneration.

    abstract::Cyclooxygenase-2 (COX-2) is thought to play a role in the pathogenesis of various neurodegenerative disorders. However, clinical trials with COX-2 inhibitors have yielded contradictory results. In the present study we investigated whether COX-2 plays a role in the behavioral and cognitive impairments seen in olfactory...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2012.07.007

    authors: Borre Y,Lemstra S,Westphal KG,Morgan ME,Olivier B,Oosting RS

    更新日期:2012-10-01 00:00:00

  • Effects of neonatal testicular hormones on preference behaviour in the rat.

    abstract::The effects of neonatal testicular hormones on preference behaviour for an oestrous female rat were investigated. A residential maze was used in which the position of the animals was registered continuously without disturbing them. Two experiments are described. In the first experiment adult male rats which had been c...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/0166-4328(84)90197-9

    authors: Merkx J

    更新日期:1984-04-01 00:00:00

  • Effect of MK 801 on priming of D1-dependent contralateral turning and its relationship to c-fos expression in the rat caudate-putamen.

    abstract::In rats with a unilateral 6-hydroxydopamine lesion of the ascending dopamine neurons, we investigated the relationship between the expression of Fos-like immunoreactivity in the caudate-putamen and contralateral turning behavior in response to dopamine agonists during the induction and expression of sensitization (pri...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/0166-4328(96)00002-2

    authors: Morelli M,Fenu S,Carta A,Di Chiara G

    更新日期:1996-09-01 00:00:00

  • Defense system psychopharmacology: an ethological approach to the pharmacology of fear and anxiety.

    abstract::Defensive behaviors comprise a set of flexible and adaptive responses to threatening situations and stimuli. In semi-natural situations affording a wide variety of responses, defensive behaviors change over time in response to information about the presence of danger, acquired through risk assessment activities. Two t...

    journal_title:Behavioural brain research

    pub_type: 杂志文章,评审

    doi:10.1016/0166-4328(93)90100-5

    authors: Blanchard RJ,Yudko EB,Rodgers RJ,Blanchard DC

    更新日期:1993-12-20 00:00:00

  • Telencephalic ablation in goldfish impairs performance in a 'spatial constancy' problem but not in a cued one.

    abstract::This work was aimed to study if goldfish telencephalon is involved differentially in spatial and cue learning. With this purpose, animals were assigned to two learning conditions, 'spatial constancy' and 'directly cued', and their performance was recorded before and after ablation of the telencephalon. During the pres...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/0166-4328(96)00014-9

    authors: Salas C,Broglio C,Rodríguez F,López JC,Portavella M,Torres B

    更新日期:1996-09-01 00:00:00

  • Blockade of opioid receptors in anterior cingulate cortex disrupts ethanol-seeking behavior in mice.

    abstract::The anterior cingulate cortex (ACC) and opioid receptors have been suggested to play a role in attributing incentive motivational properties to drug-related cues. We examined whether blockade of ACC opioid receptors would reduce cue-induced ethanol-seeking behavior in mice. We show that intra-ACC opioid receptor block...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2010.12.033

    authors: Gremel CM,Young EA,Cunningham CL

    更新日期:2011-06-01 00:00:00

  • Brain sites mediating the discriminative stimulus effects of nicotine in rats.

    abstract::Pharmacological studies suggest that the discriminative stimulus (DS) produced by nicotine is mediated centrally. The aim of the present study was to identify neuroanatomical substrates that mediate the DS properties of nicotine. Specifically, the nucleus accumbens, a brain region known to mediate the DS effects of am...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/0166-4328(95)00245-6

    authors: Shoaib M,Stolerman IP

    更新日期:1996-08-01 00:00:00

  • Dopamine signaling in the medial prefrontal cortex and amygdala is required for the acquisition of fructose-conditioned flavor preferences in rats.

    abstract::Systemic administration of dopamine (DA) D1 (SCH23390: SCH) and D2 (raclopride: RAC) antagonists blocked both acquisition and expression of fructose-conditioned flavor preferences (CFP). It is unclear what brain circuits are involved in mediating these effects. The present study investigated DA signaling within the nu...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2012.05.004

    authors: Malkusz DC,Banakos T,Mohamed A,Vongwattanakit T,Malkusz G,Saeed S,Martinez S,Bohn T,Mahmud F,Liss C,Rozvi A,Touzani K,Sclafani A,Bodnar RJ

    更新日期:2012-08-01 00:00:00

  • Serotonin controlling feeding and satiety.

    abstract::Serotonin has been implicated in the control of satiety for almost four decades. Historically, the insight that the appetite suppressant effect of fenfluramine is linked to serotonin has stimulated interest in and research into the role of this neurotransmitter in satiety. Various rodent models, including transgenic m...

    journal_title:Behavioural brain research

    pub_type: 杂志文章,评审

    doi:10.1016/j.bbr.2014.08.065

    authors: Voigt JP,Fink H

    更新日期:2015-01-15 00:00:00

  • Interaction between subclinical doses of the Parkinson's disease associated gene, α-synuclein, and the pesticide, rotenone, precipitates motor dysfunction and nigrostriatal neurodegeneration in rats.

    abstract::In most patients, Parkinson's disease is thought to emerge after a lifetime of exposure to, and interaction between, various genetic and environmental risk factors. One of the key genetic factors linked to this condition is α-synuclein, and the α-synuclein protein is pathologically associated with idiopathic cases. Ho...

    journal_title:Behavioural brain research

    pub_type: 杂志文章

    doi:10.1016/j.bbr.2016.08.056

    authors: Naughton C,O'Toole D,Kirik D,Dowd E

    更新日期:2017-01-01 00:00:00