当前位置： SCI文献检索 > Annali Italiani di Chirurgia期刊下所有文献 > Antibiotic prophylaxis in elective laparoscopic cholecystectomy is useless. A prospective multicenter study.

Antibiotic prophylaxis in elective laparoscopic cholecystectomy is useless. A prospective multicenter study.

Abstract：

AIM:We performed a prospective study to evaluate the effect of antibiotic prophylaxis (AP) on the incidence of infection in elective laparoscopic cholecystectomy (LC). MATERIAL OF STUDY:All patients were at low-medium anesthetic and infectious risk and underwent LC for benign disease. At induction of anesthesia 41 patients received ampicillin-sulbactam 3g, 40 patients received ciprofloxacin 400mg intravenously, and 53 patients received no AP. RESULTS:Postoperative infection was observed in 11 patients (8.2%) in the entire study group. All ob served infections were superficial surgical site infections (SSIs), always located at the umbilical incision. Infection occurred in 3 patients (7.3%) in ampicillin-sulbactam group, in 3 patients (7.5%) in ciprofloxacin group and in 5 patients (9.4%) in nonantibiotic group (p=0.916). Univariate analysis showed that duration of operation, placement of a drain and postoperative hospital stay were significantly associated with the development of SSIs. At multivariate analysis, only duration of operation was statistically significant in predicting SSIs. DISCUSSION:The present study did not show any advantage in the use of AP, although in case of difficult surgery the risk of SSIs is increased, in particular in the umbilical incision. In all patients, the bile culture was sterile, then the infection of the umbilical site is not due to bacterial infection from the gallbladder. CONCLUSIONS:AP in elective LC should not be routinely performed. A particular attention to the preoperative cleaning and topical antibiotic therapy of the umbilical area is advised. :In letteratura c’è un crescente consenso nell’evitare l’utilizzo della profilassi antibiotica (PA) nella colecistectomia per via laparoscopica elettiva (CLE). Tuttavia, la PA è ancora ampiamente utilizzata allo scopo di ridurre l’incidenza di infezioni postoperatorie. Abbiamo eseguito uno studio prospettico di comparazione tra utilizzo di ampicilina-sulbactam, ciprofloxacina e assenza di PA nei pazienti a basso-medio rischio anestesiologico (ASA I-III) e infettivo (patologie croniche in buon compenso) sottoposti a CLE per patologia benigna (litiasi e polipi). A 41 pazienti sono stati somministrati 3g di ampicillina- sulbactam e.v., 40 pazienti hanno assunto 400mg di ciprofloxacina e.v. e 53 pazienti non hanno effettuato nessuna PA. Nell’intero gruppo di studio si sono registrati 11 casi (8,2%) di infezione postoperatoria. Tutte le infezioni hanno coinvolto unicamente il sito chirurgico e, in particolare, l’incisione ombelicale. L’infezione si è verificata in 3 pazienti (7,3%) nel gruppo ampicilina-sulbactam, in 3 pazienti (7,5%) nel gruppo ciprofloxacina e in 5 pazienti (9,4%) nel gruppo non sottoposto a PA (p=0.916). All’analisi statistica univariata la durata dell’intervento chirurgico, il posizionamento di un drenaggio e la degenza ospedaliera, si sono dimostrati significativamente associati all’insorgenza di infezioni postoperatorie. All’analisi statistica multivariata unicamente la durata dell’intervento chirurgico è risultato significativamente associato all’insorgenza di infezioni del sito chirurgico. La PA nella CLE non è consigliabile. In caso di difficoltà durante l’intervento chirurgico, il rischio di infezione del sito chirurgico è aumentato, in particolare nella sede dell’incisione ombelicale. Si raccomanda una particolare attenzione alla disinfezione preoperatoria dell’area ombelicale anche con l’utilizzo di antibiotici per via topica.

journal_name

Ann Ital Chir

journal_title

Annali italiani di chirurgia

authors

Spaziani E,Picchio M,Di Filippo A,Greco E,Cerioli A,Maragoni M,Faccì G,Lucarelli P,Marino G,Stagnitti F,Narilli P

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

228-33

issue

3

eissn

0003-469X

issn

2239-253X

pii

S0003469X14023148

journal_volume

86

pub_type

杂志文章,多中心研究

相关文献

Annali Italiani di Chirurgia文献大全
  • [Clinical study of the imaging validity in detecting infiltration of the mesenteric-portal axis in pancreatic carcinoma].

    abstract：:The authors examine the value of different imaging techniques (CT, MRI) in the diagnosis of the involvement of the mesenteric-portal vessels in the pancreatic cancer. In 20 jaundiced patients they obtained in all cases a correct diagnosis about the etiology of the jaundice. The correspondence of the preoperative imagi...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Napolitano L,Di Donato F,Gargano E

    更新日期：2002-07-01 00:00:00

  • Laparoscopic cholecystectomy for a symptomatic cholelithiasis in a patient presenting situs viscerum inversus totalis. A case report.

    abstract：INTRODUCTION:Situs Viscerum Inversus totalis (SIT) is a rare anomaly with genetic predisposition, in which organs are translated, completely or partially, on the opposite side of the body. Generally there are no organic dysfunctions. Situs Inversus can cause difficulties in the diagnostic and therapeutic management of ...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Evoli LP,Miglionico L,Graziosi L,Cavazzoni E,Bugiantella W,Dei Santi V,Donini A

    更新日期：2012-01-01 00:00:00

  • Single incision laparoscopic surgery for hepatic hydatid disease. Report of a case.

    abstract：:A 76 year-old female patient with a long-time history of nonspecific abdominal pain admitted to our hospital. Imaging studies showed 5 cm liver hydatid cyst between segments 2 and 3. She was recommended surgery and was informed about the details of single incision laparoscopic surgery (SILS). We performed single-incis...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Karabicak I,Yuruker S,Seren DT,Kesicioglu T,Cinar H,Ozen N

    更新日期：2013-07-01 00:00:00

  • Metachronous solitary left adrenal gland metastasis of right colon cancer treated with laparoscopic approach.

    abstract：AIM:Adrenal gland metastasis are the second most common type of adrenal mass lesions after adenomas and they could be related to numerous malignancies; Literature shows that adrenal metastasis deriving from colorectal cancer are very rare. MATERIAL OF THE STUDY:A 71-year old - male patient, treated two years before wi...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Oldani A,Monni M,Soligo E,Gentilli S,Garavoglia M

    更新日期：2014-06-24 00:00:00

  • [Colonic diverticulosis complicated with perforation. Analysis of several prognosis variables and criteria for emergency surgery].

    abstract：:The aim of this study was to analyse the clinical course, surgical strategy and results in patients with perforated large bowel diverticulitis. Over a 15-year period ending in January 1997, 25 patients (13 males and 12 females; mean age 64.1 years) underwent operation for perforation of acute diverticulitis. Depending...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Ressetta G,Simeth C,Ziza F,La Bruna D,Balani A

    更新日期：1998-01-01 00:00:00

  • Neuromuscolar and vascular hamartoma of the duodenum. A clinical case and review of the literature.

    abstract：BACKGROUND AND AIMS:The NMVH of the intestine is a rare lesion, typical located in the small bowel. After the first 2 cases, reported in 1982, other 12 cases have been described, ten localized in the jejunual or ileal tract, only 1 in the cecum. SUBJECTS AND METHODS:A case of NMVH of the duodenum, simulating a Crohns ...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Minni F,Margiotta A,Guerra E,Marrano N,Selva S,Ricci C,Grottola T,Santini D

    更新日期：2005-03-01 00:00:00

  • Spleen preserving distal pancreatectomy in isolated pancreatic trauma.

    abstract：INTRODUCTION:Isolated pancreatic trauma is a rare condition and commonly come up in children or young adults.The poor initial symptoms lead to delay diagnosis and treatment. The treatment of isolated distal pancreatic trauma including the Wirsung's duct is generally distal pancreatectomy. In an emergency setting, splen...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Barut B,Ciftci F,Kayaalp C

    更新日期：2017-09-12 00:00:00

  • [Volvolus in an adult patient due to intestinal malrotation. Case report and review of literature].

    abstract：:Intestinal malrotation is a rare cause of bowel obstruction in adults and it could create a perplexing situation for surgeons not familiar with this pediatric pathology. Symptomatic patients present either acutely with bowel obstruction and intestinal ischemia with a midgut or cecal volvolus, or chronically with vague...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章,评审

    doi：

    authors： Nardone A,Tamini N,Nespoli L,Pirovano R

    更新日期：2010-09-01 00:00:00

  • Correction of an end colostomy prolapse with the Delorme technique. A case report.

    abstract：INTRODUCTION:We report a case of correction of an end colostomy prolapse with Delorme technique in an advanced stage oncologic patient to emphasize the clinical implications and advantages of this procedure. CASE REPORT:A 51-year-old male patient with a stage IV rectal adenocarcinoma underwent laparoscopy for a pallia...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Marrosu A,Paliogiannis P,Sassu MA,Attene F,Trignano M

    更新日期：2012-11-01 00:00:00

  • Rare extragonadal teratomas in children: complete tumor excision as a reliable and essential procedure for significant survival. Clinical experience and review of the literature.

    abstract：BACKGROUND:Extragonadal teratomas are rare tumors in neonates and infants and can sometimes show unusual, distinctive feature such as an unusual location, a clinical sometimes acute, presentation and a "fetiform" histotype of the lesion. We have extrapolated, from our entire experience of teratomas, 4 unusual cases, mo...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章,评审

    doi：

    authors： Paradies G,Zullino F,Orofino A,Leggio S

    更新日期：2014-01-01 00:00:00

  • [The sentinel lymph node biopsy. Evolution and convalidation of the technique].

    abstract：BACKGROUND:Sentinel node biopsy is a minimally invasive technique alternative to routine axillary dissection in breast cancer staging. This technique selects women with positive nodes who may benefit from axillary dissection, avoiding unnecessary operations in negative node biopsies. AIMS:In this article we report a 5...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Riccio PA,Marabini P,Seracchioli S,Mingolla GP,Pavanello PM,Andreini L,Nannini R,Severi S,Monti G,Ferrari G

    更新日期：2007-09-01 00:00:00

  • [Aspects of the complications after restorative proctocolectomy in the treatment of ulcerative colitis. Review of the literature and personal experience].

    abstract：PURPOSE:Analysis of complications and causes of failure after stapled restorative proctocolectomy with ileal J pouchanal anastomosis in patients with ulcerative colitis is presented. PATIENTS AND METHODS:The procedure was performed in 28 patients, 19 males (68%) and 9 females (32%); diverting ileostomy was always perf...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Colombo PL,Tinozzi FP,Abelli M,Laera MR,Testone G,Moglia P,Albertario S,Morone G,Bianchi C,Tinozzi S

    更新日期：2002-03-01 00:00:00

  • Elastofibroma: management and surgical outcome.

    abstract：:Elastofibroma is a benign slow-growing neoplasm of soft tissues, originally defined Elastofibroma dorsi because of the typical localization in the connective tissue placed between the bottom corner of the scapula and the chest wall. From 1990 to 2013 at our center, 115 patients underwent elestofibroma surgical removal...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Tambasco D,Seccia A,Cimino A,Seccia A

    更新日期：2014-03-20 00:00:00

  • Concomitant thyroid cancer in patients with primary hyperparathyroidism in an endemic goitre region.

    abstract：OBJECTIVE:Primary hyperparathyroidism (pHPT) is often accompanied by underlying thyroid pathology and 1 to 36% of these thyroid pathologies are malignant. How the identification of these lesions affects patient management is unclear. We present a single-center experience with the prevalence of concomitant thyroid cance...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Simsek B,Guldogan CE,Ozden S,Saylam B,Karabeyoglu SM,Tez M

    更新日期：2017-01-01 00:00:00

  • Acute hyperparathyroidism: our experience with 36 cases.

    abstract：OBJECTIVES:Acute hypercalcemia is a serious condition and represents a physician-surgical emergency: the difficulty in setting a precise diagnosis is due to several possibilities that can cause the condition. It is our purpose to critically evaluate the most actual schemes of treatment and the conditions that could fav...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Gasparri G,Camandona M,Mullineris B,Raggio E,Vigna S,Dei Poli M

    更新日期：2004-05-01 00:00:00

  • Epidemiological aspects of acute pancreatitis.

    abstract：:An epidemiologic analysis is carried out on incidence rate, mortality rate and etiology of acute pancreatitis, both from a general point of view and by the Spanish experience. In particular the linkages between biliary lithiasis, alcoholism and acute pancreatitis are investigated. ...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Carballo F,Martínez de Pancorbo C

    更新日期：1995-03-01 00:00:00

  • The possible role of radiofrequency as complementary treatment of locally advanced gastric cancer.

    abstract：AIM:The prognosis of locally advanced gastric cancer (T3-T4) is bad. The presence of lymph nodes (N3-N4) or haematogenous metastases (liver, lung) gets worse the evolution; principally the hepatic malignancies are cause of scarce survival. The possible use of a palliative treatment as radiofrequency ablation (the good ...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Carditello A,Scisca C,Stilo F,Parisi A,Basile M

    更新日期：2005-01-01 00:00:00

  • [Different proliferative capacity of human fibroblasts after 17 beta-estradiol administration].

    abstract：:In this study the authors examined the influence of 71, beta-estradiol on cutaneous fibroblasts taken off either from healthy patients with no family history for cancer, or from patients with breast cancer. Fibroblasts were taken from the subcutaneous tissue of the mammary gland by a biopsy carried out in each patient...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Continenza MA,Ricciardi G,De Nuntiis M,Rizzo FM,Rizzo GL

    更新日期：1994-11-01 00:00:00

  • One stage curative resection of double intestinal neuroendocrine tumors with thirty-two bilobar liver metastases. A case report.

    abstract：:Neuroendocrine tumours (NETs) of the midgut are often multifocal and have a noticeable attitude to metastasize to locoregional lymph nodes and liver. Surgery is the only curative treatment for metastatic NETs of the midgut, even though only a minority of patients are candidates to radical surgical resection. The optim...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Mirarchi M,De Raffele E,Cuicchi D,Lecce F,Cruciani G,Cola B

    更新日期：2015-07-01 00:00:00

  • Chronic pancreatitis: diagnosis and staging.

    abstract：:Chronic pancreatitis is a dynamic disease characterized on one side by a progressive destruction of the pancreatic parenchyma and change in the architecture of the gland and on the other by the impairment of its function. Diagnosis of chronic pancreatitis may be a quite easy or a very difficult attempt according to th...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章,评审

    doi：

    authors： Manes G,Kahl S,Glasbrenner B,Malfertheiner P

    更新日期：2000-01-01 00:00:00

  • [The ultrasound microbubble contrast in the diagnosis and the decisional iter of the treatment of the traumatic spleen lesions].

    abstract：AIM OF THE STUDY:To estimate our 3-year experience on the diagnosis and monitoring of the spleen traumatic lesions with the employment of ultrasound microbubbles contrast. METHOD:From the 174 patients who were joints to our department in regimen of urgency for abdominal traumatic lesions, we have estimated 24 patiens ...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Filiotis N,Sammarco G,Teodossiu G,Lazzaro R,Carbonara G,Cuccia F,Ambrosino F,Marra E,Triggiani E,Selvaggio G,Campisi A,Caruso G

    更新日期：2006-09-01 00:00:00

  • [Colostomy control using an original occluding device. A clinico-experimental study].

    abstract：:After having examined different methods as to continence colostomy, the authors introduce their own control system for the stoma. The study was carried out on 6 colostomized patients. Preliminary, the intraluminal pressure in closed colostomy was recorded. Pressure waves, largely varying from patient to patient, were ...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Aglietti L,Cosenza UM,Aglietti A,Valdarnini D,Soranna V

    更新日期：1990-01-01 00:00:00

  • Decellularized human dermal matrix produced by a skin bank A new treatment for abdominal wall defects.

    abstract：BACKGROUND:Interest is increasing for human decellularized scaffolds for their ability to favor healing and cell infiltration after transplantation, in the treatment of abdominal wall defects. The purpose of the present study is to show the clinical results obtained after the application of human decellularized dermal ...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Ghetti M,Bondioli E,Purpura V,Cenacchi G,Ruscelli P,Melandri D

    更新日期：2017-01-01 00:00:00

  • Double primary venous aneurysm of the small saphenous vein.

    abstract：:Venous aneurysms are rare lesions and of little significance in every day clinical practice. While in many cases asymptomatic they can be the cause of great morbidity due to thrombosis and subsequent possibility of pulmonary embolism. Venous aneurysms are classified in deep and superficial according to affected vein. ...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Ioannidis O,Varnalidis I,Alexandris K,Anastasiadou C,Megalopoulos A

    更新日期：2016-10-14 00:00:00

  • Pathology of dysplasia and cancer in inflammatory bowel disease.

    abstract：:In both Crohn's disease and ulcerative colitis, colorectal cancer (CRC) secondary prevention basically relies on the histology detection of dysplasia. In inflammatory bowel diseases (IBD) setting, dysplasia identifies the subgroup of patients eligible to a (more) strict surveillance program (or prophylactic colectomy)...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Mescoli C,Frego M,Rugge M

    更新日期：2011-01-01 00:00:00

  • The role of radiotherapy in the carotid stenosis.

    abstract：OBJECTIVE:Cervical radiation for head and neck cancer has been associated with an increased incidence of carotid arterial stenosis. Modern radiation therapy delivers higher doses with increasing long-term survival. In our study 50 patients with head and neck malignancies treated with radiotherapy are analized with colo...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Simonetti G,Pampana E,Di Poce I,Orsini A,Pugliese F,Izzo S,Basso L,Nicolanti V,Al Mansour M,Di Cello P,Izzo L

    更新日期：2014-11-01 00:00:00

  • The Japanese database for the staging of lung cancer.

    abstract：:From the beginning of the 60s, Japanese Lung Cancer Society (JLCS) proposed an original TNM classification of lung cancer based on a database of resected cases. The final step was the UICC classification edited in 1973. Complete hilar-mediastinal lymph node dissection was started in the same era and the concept of sta...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Tsuchiya R

    更新日期：1999-11-01 00:00:00

  • [Traumatic retroperitoneal lesions].

    abstract：:The presence of lesions on the retroperitoneum generally worsens the prognosis in traumatic pathology; it implies more attention and skills from both the medical and surgical aspect. All type of trauma, blunt or open, may involve retroperitoneal structures and organs; specifically there may be lesions on the great ves...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章,评审

    doi：

    authors： Cardia G,Loverre G,Pomarico N,Nacchiero M

    更新日期：2000-07-01 00:00:00

  • A dissection of a manometric trace of the upper esophageal sphincter and the crico-esophageal coordination.

    abstract：:A dissection of a manometric trace of the upper esophageal sphincter and the crico-esophageal coordination Although manometry is the most accurate method for diagnosing esophageal motility disorders, several patient suffering of high dysphagia remain undiagnosed. Most Authors concentrate their efforts in studying the ...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Migliore M

    更新日期：2013-03-01 00:00:00

  • Simulated use of the "grasping tie" as for colo-rectostomy after low rectal resection.

    abstract：:Simulated test of effectiveness of the original tool grasping tie, technically already illustrated in two previous papers listed in bibliography, for fixing a spongy rubber tube, simulating a rectal stump on the anvil's axle of a circular stapler, by tightening over it a nylon ribbon slip-knot (the tie). After connect...

    journal_title：Annali italiani di chirurgia

    pub_type： 杂志文章

    doi：

    authors： Picardi N

    更新日期：2003-01-01 00:00:00