Abstract:
:In this study the authors examined the influence of 71, beta-estradiol on cutaneous fibroblasts taken off either from healthy patients with no family history for cancer, or from patients with breast cancer. Fibroblasts were taken from the subcutaneous tissue of the mammary gland by a biopsy carried out in each patients on the same quadrant of the granular surface. Soon after biopsy, the tissue fragments have been washed, dished ed incubated in RPMI at 37 degrees C in a humidified atmosphere of 5% CO2 and 95% air. The action of the hormone was evaluated by the means of cells count for field, in 20 fields in each dish with an inverted microscope (20 x magnification). The results demonstrated that cutaneous fibroblasts from patients with breast cancer show higher values of cell density than those from healthy one. This phenomenon is present both in basal conditions and after hormonal treatment. Two different dosages were used, but only the highest (100 microliters/ml of 17, beta-estradiol) was responsible for an increase of the cell density in all of the treated patients as compared the control groups. These data suggests the presence of a threshold dosage for the estrogens. Below such a dosage there are no effects on cellular growth.
journal_name
Ann Ital Chirjournal_title
Annali italiani di chirurgiaauthors
Continenza MA,Ricciardi G,De Nuntiis M,Rizzo FM,Rizzo GLsubject
Has Abstractpub_date
1994-11-01 00:00:00pages
715-8issue
6eissn
0003-469Xissn
2239-253Xjournal_volume
65pub_type
杂志文章abstract:INTRODUCTION:Factor VII deficiency is a rare cause of haemorrhagic syndrome. The Authors describe a case of a 46 years old patient with congenital factor VII deficiency that successfully underwent breast surgery after treatment with Novoseven® before the procedure. MATERIALS AND METHODS:The AA used the schedule report...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:2014-06-25 00:00:00
abstract::Hepatocellular carcinoma (HCC) is a slowly growing tumor, whose natural history is not completely known. Since the hepatocarcinogenetic process may evolve for years in a stepwise fashion from premalignant to overt HCC, detection of early, better treatable tumors is made possible by surveillance of patients at risk. A ...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:A high rate of association between neuroendocrine tumors (NETs) and secondary primary malignancy (SPM) has been described in literature and this association can occur either in a synchronous or a metachronous presentation. A wide range of hypothesis has been postulated to explain the high rate of association...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
doi:
更新日期:2017-10-04 00:00:00
abstract::Hemosuccus pancreaticus is a rare clinical condition, defined as a bleeding from an artery around the pancreas or a lesion on the pancreas, to the pancreatic duct. The intensity of bleeding can vary from occult bleeding to life threatening massive acute bleeding. In this article, we aimed to present a 68-year-old man ...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
doi:
更新日期:2020-01-01 00:00:00
abstract::By long experience with the problems on hiatal hernias and reflux the author summarizes and analyzes errors and progress in development, interpretation, diagnostic methods and treatment. After the pioneer work done by Akerlund 1926 the hiatal hernia was a sometimes dangerous surgical target. It remained for a long tim...
journal_title:Annali italiani di chirurgia
pub_type: 社论,评审
doi:
更新日期:1993-05-01 00:00:00
abstract::The authors review the results of clinical experiences regarding arterial and venous homografts. For the treatment of mycotic aneurysms and infected prostheses, in situ repair with vascular homografts represents a valuable alternative to conventional surgical treatments. In fact the large caliber arterial homografts a...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
doi:
更新日期:2001-03-01 00:00:00
abstract:AIM:The liver is the most common site of metastases in colorectal cancer but metastases seem to be less common in patients with a chronically liver damage. The aim of our study was to assess the development of metachronous liver metastases in patients affected by HBV or HCV related liver diseases. MATERIAL OF STUDY:We...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:2013-05-01 00:00:00
abstract::Six cases of anal canal squamous carcinoma are presented. The authors precise the present view about pathological, epidemiological, clinical and therapeutical aspects of these lesions. They stress, also, the primary role of embryology and anatomy in the oncogenesis of such tumours; the importance to single out specifi...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
doi:
更新日期:1994-07-01 00:00:00
abstract:UNLABELLED:Cystic lymphangioma is a rare benign tumor commonly located in the head or neck. Approximately 100 adult cases have been reported in the literature. The etiopathogenesis is unclear, though trauma has been suggested as one of the possible causes. CASE REPORT:We report a case of recurrent cystic lymphangioma ...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
doi:
更新日期:2014-01-01 00:00:00
abstract::Primary aortoenteric fistulas (PAEF) are rare entities associated with a high mortality. Although several causes have been reported, their occurrence is usually due to erosion of an abdominal aortic aneurysm into the intestinal tract. The most common sites for the fistula are the third and fourth portions of duodenum....
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:2004-05-01 00:00:00
abstract::Gynaecomastia is a disease with a high incidence (approximately 65% of adult males between 15 and 40 Ys.). In this paper the authors present their experience about the medical and surgical treatment comparing different surgical techniques: adenomammectomy, liposuction and liposuction associated with adenomammectomy. 6...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:1999-09-01 00:00:00
abstract::After radical surgery for colo-rectal cancer, the prevention of local recurrence and/or distant metastasis, represents the key factor of the active measures adopted by surgeons and oncologists. Recent trends of the research in this field, show that an effective chemotherapy is the goal to achieve. Our review of the li...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
doi:
更新日期:1993-03-01 00:00:00
abstract::Intestinal malrotation is a rare cause of bowel obstruction in adults and it could create a perplexing situation for surgeons not familiar with this pediatric pathology. Symptomatic patients present either acutely with bowel obstruction and intestinal ischemia with a midgut or cecal volvolus, or chronically with vague...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
doi:
更新日期:2010-09-01 00:00:00
abstract::Metastatic cancer to the liver from gastrointestinal primary should be treated with surgical resection as a first priority. Biological and physical restrictions on the dissemination of metastatic cancer result in disease dissemination isolated within the liver in selected patients. Although there are numerous prognost...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
doi:
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to review the characteristics, intraoperative and radiological findings of abdominal wall endometriosis (AWE). METHODS:This retrospective observational cohort study was executed through analysis of the medical records of patients who underwent excision of AWE between January 2000 and...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:2018-01-01 00:00:00
abstract::Determination of serum pancreatic enzymes remains the gold standard for the diagnosis of acute pancreatitis. Clinical symptoms and signs are of major importance in suspecting the disease, but they are not accurate enough to confirm the diagnosis. Among pancreatic enzymes, total amylase, pancreatic isoamylase and lipas...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:1995-03-01 00:00:00
abstract::Cathartic colon is a rare pathology which hits old people and is radiologically characterized by dolichocolon and megarectum. It is nearly sure that the unusual length of the whole colon might be the first source of the cathartic disease. Rectal ampulla dilatation (megarectum) is due to the extended use of laxatives w...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Venous leg ulcer is the most frequent cause of trophic lesions of the limbs in patients with chronic venous insufficiency. Appropriate management of cutaneous vascular lesions is based on systemic, vascular and local assessment. The Authors used a protease-modulating matrix in 126 patients suffering from venous leg ul...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Fournier's gangrene is a synergistic necrotic fasciitis or myositis of genitalia, perineum and abdominal wall. Several etiologic factors have been reported, microorganisms isolated and co-morbidity factors identified. Immediate and accurate diagnosis decreases mortality rate, which ranges from 3-67%. Aggress...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND AND AIMS:vertical banded gastroplasty (GPV) is the most frequently performed restrictive procedure for morbid obesity, but long-term follow-up is almost nonexistent. A poor outcome after GPV and a low quality of life has been reported. The aim of the study was to determine long-term outcome after 5 years fol...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:2003-11-01 00:00:00
abstract::Carcinoid tumors of the ampulla are an uncommon finding. The authors report an asymptomatic case of ampullary carcinoid in which the diagnosis was obtained only with definitive histology after radical surgery. The differential diagnosis of these tumors is quite difficult, mostly because they are often asymptomatic. Su...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Neuroendocrine carcinoma cases, more frequent in the GI tract, have rarely been reported in extrapulmonary areas. Neuroendocrine carcinoma of the bladder is one of the malignancies with a poor prognosis, which is expected to cause rapid metastases. In addition, neuroendocrine carcinoma of the bladder constitutes < 1% ...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:2019-03-04 00:00:00
abstract::Peritoneal mesothelioma is a rare neoplasm (annual incidence: 1-2 cases per million in the general population) and forms about 10% of all mesotheliomas. The authors report a case of malignant mesothelioma of the peritoneum in a male, 61 years old. After laparotomy the patient was treated with intraperitoneal administr...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract:INTRODUCTION:Prognosis of colon cancer is worse if complications are present at the moment of diagnosis. The high mortality rate with surgery in emergency in such cases needs a careful reflection about the best suitable operation to perform. MATERIALS AND METHODS:107 consecutive patients observed along a 9 year-period...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract::Anal stenosis is a fibrous narrowing of the anal channel. It develops, in most cases, in the aftermath of proctologic surgical procedures with extensive anoderm excision or in the presence of chronic anal inflammation in patients with Crohn Disease. However rare, this condition is thoroughly debilitating for the patie...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
doi:
更新日期:2018-01-01 00:00:00
abstract::The presence of lesions on the retroperitoneum generally worsens the prognosis in traumatic pathology; it implies more attention and skills from both the medical and surgical aspect. All type of trauma, blunt or open, may involve retroperitoneal structures and organs; specifically there may be lesions on the great ves...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
doi:
更新日期:2000-07-01 00:00:00
abstract::To date the basic guidelines in surgical oncology of the stomach may be summarized in the correct definition of "R0" exeresis (curative operation), but there is still much debate on which should practically be the extension of the gastric resection and which the kind of lymphatic dissection in order to fulfill all the...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
doi:
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:Esophageal anastomotic leaks are associated with significant morbidity and mortality. The purpose of this study was to retrospectively assess the role of the anastomotic positioning (thoracic or cervical) on the incindence of the anastomotic leak and its severity. METHODS:In the period 2002-07, we have perfo...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:2013-03-01 00:00:00
abstract::Thrombosed haemorrhoids and anal haematomas are very usual in patients with haemorrhoids. Conservative treatment and surgery are effective by the features and time of presentation. Authors refer about pathological and clinical findings and discuss the treatment. ...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章,评审
doi:
更新日期:1995-11-01 00:00:00
abstract:OBJECTIVES:Acute hypercalcemia is a serious condition and represents a physician-surgical emergency: the difficulty in setting a precise diagnosis is due to several possibilities that can cause the condition. It is our purpose to critically evaluate the most actual schemes of treatment and the conditions that could fav...
journal_title:Annali italiani di chirurgia
pub_type: 杂志文章
doi:
更新日期:2004-05-01 00:00:00