Interactions between specific parameters of MDMA use and cognitive and psychopathological measures.

Abstract:

:The aim of the present study was to investigate the relevance of different parameters of 3,4-methylenedioxymethamphetamine (MDMA) use, including age of first use, cumulative lifetime dose and highest daily dose for predicting cognitive performance and self-reported psychopathology. Moreover, interactions between those parameters were examined. Ninety-six new MDMA users were interviewed to assess their drug use, and they completed a battery of cognitive tests concerning attention and information processing speed, episodic memory and executive functioning and self-reported psychopathology. Subjects participated again after 1year to provide follow-up data. Significant associations between age of first use and cumulative lifetime dose have been found for attention and information processing speed. Furthermore, the results showed a significant effect of age of first use on the recognition performance of the episodic memory. The findings of the current study provide a first estimation of the interactions between different MDMA use parameters. Future research should focus upon additional parameters of drug use and concentrate on consequent follow-up effects.

authors

Wagner D,Adolph S,Koester P,Becker B,Gouzoulis-Mayfrank E,Daumann J

doi

10.1016/j.pnpbp.2014.12.004

subject

Has Abstract

pub_date

2015-04-03 00:00:00

pages

32-7

eissn

0278-5846

issn

1878-4216

pii

S0278-5846(14)00241-3

journal_volume

58

pub_type

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