Evaluation of an emergency cricothyrotomy instrument.

abstract：OBJECTIVE:To study whether noninvasive pressure support ventilation (NIPSV) with helium/oxygen (He/oxygen), which can reduce dyspnea, PaCO2, and work of breathing more than NIPSV with air/oxygen in decompensated chronic obstructive pulmonary disease, could have beneficial consequences on outcome and hospitalization cos...

journal_title：Critical care medicine

authors： Jolliet P,Tassaux D,Roeseler J,Burdet L,Broccard A,D'Hoore W,Borst F,Reynaert M,Schaller MD,Chevrolet JC

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:Although misperceptions about prognosis by surrogates in ICUs are common and influence treatment decisions, there is no validated, practical way to measure the effectiveness of prognostic communication. Surrogates' subjective ratings of quality of communication have been used in other domains as markers of ef...

journal_title：Critical care medicine

authors： Chiarchiaro J,Buddadhumaruk P,Arnold RM,White DB

更新日期：2015-03-01 00:00:00

abstract：:Gastric mucosal damage occurs in critically ill patients in intensive care units and develops in the setting of severe physiologic stress. Within 24 hrs of admission to the intensive care unit, 75% to 100% of critically ill patients demonstrate evidence of stress-related mucosal disease. Stress ulcers present a risk o...

journal_title：Critical care medicine

authors： Fennerty MB

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:Review data obtained from high-frequency oscillatory ventilation (HFOV) and mechanical test lung models with respect to delivered tidal volume, distal pressure transmission, endotracheal tube cuff leaks, and simulated clinical conditions. DESIGN:Review of selected studies from PubMed, published abstracts, an...

journal_title：Critical care medicine

authors： Van de Kieft M,Dorsey D,Morison D,Bravo L,Venticinque S,Derdak S

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:Sepsis is life-threatening organ dysfunction due to dysregulated host responses to infection. Current knowledge of human B-cell alterations in sepsis is sparse. We tested the hypothesis that B-cell loss in sepsis involves distinct subpopulations of B cells and investigated mechanisms of B-cell depletion. DES...

journal_title：Critical care medicine

authors： Shankar-Hari M,Fear D,Lavender P,Mare T,Beale R,Swanson C,Singer M,Spencer J

更新日期：2017-05-01 00:00:00

abstract：:A patient with neurogenic pulmonary edema was successfully treated with the alpha-blocking agent, chlorpromazine. A pathophysiologic basis for this drug's efficacy is discussed. ...

journal_title：Critical care medicine

authors： Wohns RN,Tamas L,Pierce KR,Howe JF

更新日期：1985-03-01 00:00:00

abstract：:Eleven patients in hypertensive crisis were treated with iv sodium nitroprusside (SNP). In all cases, rapid clinical improvement was obtained. Nevertheless, 9 patients developed progressive resistance to the hypotensive effect of the drug. For the first 2 h, the mean infusion rate was 1.68 +/- 0.64 micrograms/kg . min...

journal_title：Critical care medicine

authors： Rouby JJ,Gory G,Bourrelli B,Glaser P,Viars P

更新日期：1982-05-01 00:00:00

abstract：OBJECTIVE:To determine a) if the admission osmole gap, the difference between osmolality and osmolarity, is the same in the neurologic-neurosurgical intensive care unit (NNICU) population as in healthy controls; b) which of 11 osmole gap formulas, or osmolality, correlates best with mannitol serum concentrations; c) wh...

journal_title：Critical care medicine

authors： García-Morales EJ,Cariappa R,Parvin CA,Scott MG,Diringer MN

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:Significant mortality in patients with sepsis results from the development of multiple organ dysfunction syndrome. Small-volume resuscitation with 7.5% NaCl hypertonic saline has been proposed to restore physiologic hemodynamics in hemorrhagic shock. Therefore, we hypothesized that hypertonic saline resuscita...

journal_title：Critical care medicine

authors： Shih CC,Chen SJ,Chen A,Wu JY,Liaw WJ,Wu CC

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:Acute renal tubular injury is a serious complication in the postoperative period, which is associated with high mortality and increased ICU stay. We aimed to demonstrate the protective effect of rhEPO against acute tubular injury induced by ischemia-reperfusion and to explore the mechanism of canonical transi...

journal_title：Critical care medicine

authors： Shen S,Jin Y,Li W,Liu X,Zhang T,Xia W,Wang Y,Ma K

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:To determine whether low-dose dopamine administration reduces the incidence or severity of acute renal failure, need for dialysis, or mortality in patients with critical illness. DATA SOURCES AND STUDY SELECTION:We performed a MEDLINE search of literature published from 1966 to 2000 for studies addressing th...

journal_title：Critical care medicine

authors： Kellum JA,M Decker J

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:To describe three female patients of one family with different phenotypes of the same mutation of the ornithine transcarbamylase gene. X-linked inherited ornithine transcarbamylase deficiency is the most frequent urea cycle disorder. Many of the hemizygous males die during the neonatal period. Women, who are ...

journal_title：Critical care medicine

authors： Legras A,Labarthe F,Maillot F,Garrigue MA,Kouatchet A,Ogier de Baulny H

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:To investigate whether inhibition of cyclooxygenase-2, a critical component of the inflammatory pathway, is neuroprotective in a neonatal rat model of cerebral hypoxia-ischemia. The development of brain inflammation largely contributes to neonatal brain injury that may lead to a lifetime of neurologic deficit...

journal_title：Critical care medicine

authors： Fathali N,Ostrowski RP,Lekic T,Jadhav V,Tong W,Tang J,Zhang JH

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:Although contraindicated, there are situations when a patient who has recently taken a phosphodiesterase 5 inhibitor (e.g., sildenafil) might need intravenous nitroglycerin (NTG) treatment. This study determined if, and at what dose, intravenous NTG could be administered safely to men with coronary artery dis...

journal_title：Critical care medicine

authors： Parker JD,Bart BA,Webb DJ,Koren MJ,Siegel RL,Wang H,Malhotra B,Jen F,Glue P

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVES:Cognitive deficits after traumatic brain injury are a leading cause of disability worldwide, yet no effective pharmacologic treatments exist to improve cognition. Traumatic brain injury increases proinflammatory cytokines, which trigger excess function of α5 subunit-containing γ-aminobutyric acid type A rece...

journal_title：Critical care medicine

authors： Khodaei S,Avramescu S,Wang DS,Sheng H,Chan NK,Lecker I,Fernandez-Escobar A,Lei G,Dewar MB,Whissell PD,Baker AJ,Orser BA

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVES:We previously reported gene expression-based endotypes of pediatric septic shock, endotypes A and B, and that corticosteroid exposure was independently associated with increased mortality among pediatric endotype A patients. The Vasopressin vs Norepinephrine as Initial Therapy in Septic Shock trial tested th...

journal_title：Critical care medicine

authors： Wong HR,Hart KW,Lindsell CJ,Sweeney TE

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:To examine the efficacy and safety of proton pump inhibitors in comparison with histamine-2 receptor antagonists for stress-related upper gastrointestinal bleeding prophylaxis among critical care patients. DATA SOURCES:PubMed, EMBASE, Cochrane Library, and ClinicalTrials.gov. STUDY SELECTION:Randomized, con...

journal_title：Critical care medicine

authors： Lin PC,Chang CH,Hsu PI,Tseng PL,Huang YB

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:Limited data are available on the influence of sedation for critical care therapy with the widely used anesthetic propofol on recovery from acute traumatic brain injury. To establish the influence of propofol on endogenous neurogenesis and functional recovery after traumatic brain injury, rats were sedated wi...

journal_title：Critical care medicine

authors： Thal SC,Timaru-Kast R,Wilde F,Merk P,Johnson F,Frauenknecht K,Sebastiani A,Sommer C,Staib-Lasarzik I,Werner C,Engelhard K

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:The elevation of the percentage of regulatory CD4+CD25+ T lymphocytes (Treg) has been recently described during septic shock. The objective of the present study was to investigate whether this increased percentage was due to Treg proliferation. DESIGN:Observational study. SETTING:Adult intensive care units ...

journal_title：Critical care medicine

authors： Venet F,Pachot A,Debard AL,Bohé J,Bienvenu J,Lepape A,Monneret G

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVES:Low tidal volume (= tidal volume ≤ 6 mL/kg, predicted body weight) ventilation using volume control benefits patients with acute respiratory distress syndrome. Airway pressure release ventilation is an alternative to low tidal volume-volume control ventilation, but the release breaths generated are variable ...

journal_title：Critical care medicine

authors： Hirshberg EL,Lanspa MJ,Peterson J,Carpenter L,Wilson EL,Brown SM,Dean NC,Orme J,Grissom CK

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:To analyze plasma interferon-gamma and interleukin-10 concentrations in patients with systemic meningococcal disease and patients with severe Gram-positive septic shock caused by Streptococcus pneumoniae or Staphylococcus aureus. To study the in vitro cytokine (interferon-gamma and interleukin-10) responses i...

journal_title：Critical care medicine

authors： Bjerre A,Brusletto B,Høiby EA,Kierulf P,Brandtzaeg P

更新日期：2004-02-01 00:00:00

abstract：:Fluosol-DA 20% (FDA-20) resuscitation has been proposed for prehospital therapy of hemorrhagic shock (HS). Acute HS (mean arterial pressure 60 mm Hg X 90 min, then 40 mm Hg X 30 min) in 24 splenectomized dogs was treated with 50 ml/kg of lactated Ringer's solution (RL) plus a volume equal to 105% of shed blood volume ...

journal_title：Critical care medicine

authors： Elliott LA,Ledgerwood AM,Lucas CE,McCoy LE,McGonigal M,Sullivan MW

更新日期：1989-02-01 00:00:00

abstract：OBJECTIVE:Acute lung injury is a detrimental complication for victims of burn accidents. Airway obstruction plays an important role in pulmonary dysfunction in these patients. In this study, we tested the hypothesis that aerosolized anticoagulants will reduce the degree of airway obstruction and improve pulmonary funct...

journal_title：Critical care medicine

authors： Enkhbaatar P,Cox RA,Traber LD,Westphal M,Aimalohi E,Morita N,Prough DS,Herndon DN,Traber DL

更新日期：2007-12-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to determine the prognostic value of sublingual PCO2 (P(SL)CO2), lactate concentration, and mixed venous oxygen saturation (S(MV)O2) in hemodynamically unstable intensive care patients and, additionally, to compare the temporal changes of these variables in response to treatment....

journal_title：Critical care medicine

authors： Marik PE,Bankov A

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To determine alterations in intestinal epithelial permeability to solutes in burn injured rats with and without Enterococcus faecalis infection and the role of neutrophils in the intestinal permeability changes. DESIGN:Prospective sham-controlled animal study. SETTING:University research laboratory. SUBJEC...

journal_title：Critical care medicine

authors： Samonte VA,Goto M,Ravindranath TM,Fazal N,Holloway VM,Goyal A,Gamelli RL,Sayeed MM

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVE:Gabexate mesilate is a synthetic protease inhibitor capable of inhibiting both coagulation and cytokine production by monocytes. To investigate whether gabexate mesilate is useful for the prevention of posttraumatic spinal cord injury, we examined its effect on compression trauma-induced spinal cord injury in...

journal_title：Critical care medicine

authors： Taoka Y,Okajima K,Uchiba M,Murakami K,Kushimoto S,Johno M,Naruo M,Okabe H,Takatsuki K

更新日期：1997-05-01 00:00:00

abstract：:The hospital records of 7 patients with severe bronchopulmonary dysplasia (BPD) were reviewed. All patients were ventilator dependent for prolonged periods (mean duration intermittent mandatory ventilation (IMV) 14.3 +/- 3.5 months) but eventually were successfully weaned from mechanical ventilation and sent home. The...

journal_title：Critical care medicine

authors： Morray JP,Fox WW,Kettrick RG,Downes JJ

更新日期：1981-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of spontaneous gasping on cardiorespiratory functions and the ability to resuscitate during experimental cardiac arrest. DATA SOURCES:Studies in rat and pig models during cardiac arrest and cardiopulmonary resuscitation (CPR). STUDY SELECTION:We retrospectively examined the role of sp...

journal_title：Critical care medicine

authors： Yang L,Weil MH,Noc M,Tang W,Turner T,Gazmuri RJ

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the accuracies of the respiratory rate/tidal volume ratio (rate/volume ratio), minute volume, and negative inspired force in predicting weaning outcome in postoperative mechanically ventilated patients. DESIGN:A prospective, observational study. SETTING:Surgical intensive care unit of a 270-bed ...

journal_title：Critical care medicine

authors： Jacob B,Chatila W,Manthous CA

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:Sepsis is a frequent cause of admission, but incidence rates based on administrative data have previously produced large differences in estimates. The aim of the study was to estimate the incidence of community-acquired sepsis based on patients' symptoms and clinical findings at arrival to the hospital. DESI...

journal_title：Critical care medicine

authors： Henriksen DP,Laursen CB,Jensen TG,Hallas J,Pedersen C,Lassen AT

更新日期：2015-01-01 00:00:00