Recombinant human erythropoietin pretreatment attenuates acute renal tubular injury against ischemia-reperfusion by restoring transient receptor potential channel-6 expression and function in collecting ducts.

abstract：OBJECTIVE:Our first objective was to determine a blood lactate threshold predictive of survival in human immunodeficiency virus patients experiencing lactic acidosis related to nucleoside analogs, and second, to test l-carnitine for the treatment of patients exceeding that threshold. DESIGN:a) Retrospective study usin...

journal_title：Critical care medicine

authors： Claessens YE,Cariou A,Monchi M,Soufir L,Azoulay E,Rouges P,Goldgran-Toledano D,Branche F,Dhainaut JF

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:A lack of intensive care units beds in Israel results in critically ill patients being treated outside of the intensive care unit. The survival of such patients is largely unknown. The present study's objective was to screen entire hospitals for newly deteriorated patients and compare their survival in and ou...

journal_title：Critical care medicine

authors： Simchen E,Sprung CL,Galai N,Zitser-Gurevich Y,Bar-Lavi Y,Levi L,Zveibil F,Mandel M,Mnatzaganian G,Goldschmidt N,Ekka-Zohar A,Weiss-Salz I

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:Life-threatening conditions cause severe changes in the organization and conformation of macromolecules, creating urgent requirements for protein repair to ensure survival. As molecular chaperones, heat shock proteins (HSP) that have specialized functions in protein folding are now well established to restore...

journal_title：Critical care medicine

authors： Christians ES,Yan LJ,Benjamin IJ

更新日期：2002-01-01 00:00:00

abstract：:Laboratory evaluation and use of the Engström metabolic computer (EMC) in a clinical setting are described. The accuracy of the EMC was tested using an inert gas dilution technique. Mean errors in oxygen consumption (VO2) and CO2 production compared with predicted values were less than 2% of predicted, and generally l...

journal_title：Critical care medicine

authors： Regan CJ,Snowdon SL,Campbell IT

更新日期：1990-08-01 00:00:00

abstract：:Twenty preterm infants in respiratory distress, each with an umbilical catheter in place, were studied during their first 24 h of hospitalization, to determine the effects of continuous transcutaneous oxygen (PtcO2) monitoring on the frequency of arterial blood gas (ABG) determinations and on the incidence of hypoxia ...

journal_title：Critical care medicine

authors： Kilbride HW,Merenstein GB

更新日期：1984-02-01 00:00:00

abstract：OBJECTIVES:The purposes of this report are to a) describe the University of Michigan experience with venoarterial or venovenous extracorporeal life support for severe pediatric pulmonary rescue therapy, and b) examine survivors and nonsurvivors for differences that might be useful for examination in future, prospective...

journal_title：Critical care medicine

authors： Moler FW,Custer JR,Bartlett RH,Palmisano J,Meliones JN,Delius RE,Braden EI,Snedecor S

更新日期：1992-08-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that PaCO2 levels generated during permissive hypercapnia may enhance arterial oxygenation, when ventilation is maintained. DESIGN:Prospective study. SETTING:Research laboratory in a hospital. SUBJECTS:One group of eight mongrel dogs (four male; four female). INTERVENTIONS:The dogs ...

journal_title：Critical care medicine

authors： Torbati D,Mangino MJ,Garcia E,Estrada M,Totapally BR,Wolfsdorf J

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVES:Previous studies in adults suggest that various types of physiologic stress appear to decrease phagocytic cell function. Adherence and chemotaxis of, and phagocytosis and bacterial killing by, neonatal neutrophils are altered compared with adult neutrophil function. Stresses encountered by the fetus and neon...

journal_title：Critical care medicine

authors： Beachy JC,Weisman LE

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVE:To study the course of gastric regional PCO2 (PrCO2) in patients with cardiogenic shock requiring intra-aortic balloon (IAB) counterpulsation and the prognostic value of PrCO2 in this patient population. DESIGN:A prospective, observational clinical study. SETTING:Medical intensive care unit in a university ...

journal_title：Critical care medicine

authors： Janssens U,Graf J,Koch KC,vom Dahl J,Hanrath P

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVES:Although highly active antiretroviral therapy has led to improved survival in HIV-infected individuals, outcomes for HIV-infected patients with sepsis in the post-highly active antiretroviral therapy era are conflicting. Access to highly active antiretroviral therapy and healthcare disparities continue to af...

journal_title：Critical care medicine

authors： Cribbs SK,Tse C,Andrews J,Shenvi N,Martin GS

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:To study the impact of a clinical pharmacist in a pediatric intensive care unit. The goals of the study were to determine the type and quantity of patient care interventions recommended by a clinical pharmacist and to specifically examine cost savings (or loss) that resulted from clinical pharmacist recommend...

journal_title：Critical care medicine

authors： Krupicka MI,Bratton SL,Sonnenthal K,Goldstein B

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:To address issues of antibiotic dosing during sustained low-efficiency dialysis by using available pharmacokinetic data, intermittent and continuous renal replacement therapy dialysis guidelines, and our experience with sustained low-efficiency dialysis. DATA RESOURCES:Published clinical trials, case reports...

journal_title：Critical care medicine

authors： Bogard KN,Peterson NT,Plumb TJ,Erwin MW,Fuller PD,Olsen KM

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVES:Mild decrease in core temperature (therapeutic hypothermia) provides lasting neuroprotection following cardiac arrest or cerebral ischemia. However, current methods for producing therapeutic hypothermia trigger a cold-defense response that must be countered by sedatives, muscle paralytics, and mechanical ven...

journal_title：Critical care medicine

authors： Feketa VV,Zhang Y,Cao Z,Balasubramanian A,Flores CM,Player MR,Marrelli SP

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:In the ICU, discussions between clinicians and surrogate decision makers are often accompanied by conflict about a patient's prognosis or care plan. Trust plays a role in limiting conflict, but little is known about the determinants of trust in the ICU. We sought to identify the dimensions of trust and clinic...

journal_title：Critical care medicine

authors： Hutchison PJ,McLaughlin K,Corbridge T,Michelson KN,Emanuel L,Sporn PH,Crowley-Matoka M

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:Light chains κ and λ are immunoglobulin constituents but also circulate independently in blood as free light chains. We investigated whether a concomitant abnormality in free light chain and immunoglobulin levels could identify a high risk of death sepsis subpopulation to inform future IV immunoglobulin tria...

journal_title：Critical care medicine

authors： Shankar-Hari M,Singer M,Spencer J

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Information booklets have not been assessed by the families of intensive care unit (ICU) patients. This study explored the information that the relatives of adult ICU patients wanted to find in the information booklets. DESIGN:Multicenter survey. SETTING:Twenty-three French ICUs. SUBJECTS:One close relativ...

journal_title：Critical care medicine

authors： Soltner C,Lassalle V,Galienne-Bouygues S,Pottecher J,Floccard B,Delapierre L,Jungfer F,Sargentini C,Alberti C,Beydon L,Lifrea Group.

更新日期：2009-07-01 00:00:00

abstract：:Ten infants with acquired subglottic stenosis were treated successfully using the anterior cricoid split operation. Eight had been preterm infants who required endotracheal intubation and assisted ventilation for the respiratory distress syndrome. Two had been born at term; 1 required mechanical ventilation for aspira...

journal_title：Critical care medicine

authors： Frankel LR,Anas NG,Perkin RM,Seid AB,Peterson B,Park SM

更新日期：1984-04-01 00:00:00

abstract：OBJECTIVES:To determine whether aerosolized antibiotics can be delivered efficiently to the lower respiratory tract in mechanically ventilated patients and to define possible clinical responses to these agents. DESIGN:Prospective serial study with cases as their own control. SETTING:A 10-bed respiratory care unit for...

journal_title：Critical care medicine

authors： Palmer LB,Smaldone GC,Simon SR,O'Riordan TG,Cuccia A

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:To evaluate whether current criteria for the diagnosis of brain death fulfill the requirement for the "irreversible cessation of all functions of the entire brain, including the brainstem." DATA SOURCES:Clinical, philosophical, legal, and public policy literature on the subject of brain death. DATA EXTRACTI...

journal_title：Critical care medicine

authors： Truog RD,Fackler JC

更新日期：1992-12-01 00:00:00

abstract：:Cerebral arteriovenous differences in oxygen content [C(a-v)O2] and glucose content [C(a-v)gluc] were used to predict outcome in 20 patients who remained comatose after resuscitation for cardiopulmonary arrest. Cerebral prognosis was good when C(a-v)O2 values were greater than 1.8 mMol/L and the oxygen glucose index (...

journal_title：Critical care medicine

authors： Ducassé JL,Marc-Vergnes JP,Cathala B,Genestal M,Lareng L

更新日期：1984-10-01 00:00:00

abstract：OBJECTIVE:To determine if there is a difference in nosocomial pneumonia frequency rate in mechanically ventilated trauma patients treated with sucralfate vs. ranitidine for stress ulcer prophylaxis. DESIGN:Prospective, randomized trial. SETTING:A 640-bed urban teaching hospital and trauma center. PATIENTS:Ninety-two...

journal_title：Critical care medicine

authors： Pickworth KK,Falcone RE,Hoogeboom JE,Santanello SA

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVES:To review the intensive care unit experience of patients with admitted or acquired nosocomial endocarditis (NE) defined according to the Duke criteria. DESIGN:Prospective, cohort study. SETTING:University teaching hospital. PATIENTS:We reviewed the records of 22 patients documented with NE during a 6-yr p...

journal_title：Critical care medicine

authors： Gouëllo JP,Asfar P,Brenet O,Kouatchet A,Berthelot G,Alquier P

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVE:To determine the association of pulmonary artery catheter (PAC) use with in-hospital mortality. DESIGN:Prospective, observational study. SETTING:The medical intensive care units (MICU) of two teaching hospitals. METHODS:The study included 751 adults who were admitted to the MICU, excluding those who stayed...

journal_title：Critical care medicine

authors： Afessa B,Spencer S,Khan W,LaGatta M,Bridges L,Freire AX

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:To study the importance of endothelin-1-induced vasoconstriction in a model of acute and maintained low cardiac output, by investigating regional changes within the mesenteric and particularly the intestinal mucosal circulation. DESIGN:Prospective, controlled animal study. SETTING:University-affiliated rese...

journal_title：Critical care medicine

authors： Burgener D,Laesser M,Treggiari-Venzi M,Oi Y,Jolliet P,Strasser S,Hadengue A,Aneman A

更新日期：2001-08-01 00:00:00

abstract：:Acute kidney injury (AKI) is commonly and increasingly encountered in patients with critical illness. In the past, epidemiologic studies have consistently found that oliguria further increases the risk of death from AKI. Compared with patients outside the intensive care unit (ICU), critically ill patients are more lik...

journal_title：Critical care medicine

authors： Bagshaw SM,Bellomo R,Kellum JA

更新日期：2008-04-01 00:00:00

abstract：:offstudied hemodynamic and renal effects of increasing the dosage of dopamine (DP) by 5 micrograms/kg X min, in 7 patients with peritonitis and clinical findings of septic shock, all of whom were already receiving variable dosages of DP. Stroke index (SI) (p less than .01), except in 3 cases, and mean arterial pressur...

journal_title：Critical care medicine

authors： de la Cal MA,Miravalles E,Pascual T,Esteban A,Ruiz-Santana S

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that the effects of intravenous injection of latex particles would demonstrate the contribution of phagocytosis by mononuclear phagocytes to the development of Escherichia coli-induced acute lung injury in neutropenic guinea pigs. DESIGN:Prospective, controlled, experimental study. Int...

journal_title：Critical care medicine

authors： Ishizaka A,Hasegawa N,Sayama K,Urano T,Nakamura H,Sakamaki F,Soejima K,Waki Y,Tasaka S,Nakamura M,Matsubara H,Kanazawa M

更新日期：1996-06-01 00:00:00

abstract：:Twenty-one patients who underwent cardiopulmonary bypass for myocardial revascularization received postoperatively controlled mechanical ventilation (CMV) or intermittent mandatory ventilation (IMV), with or without positive end-expiratory pressure (PEEP). Functional residual capacity (FRC), right-to-left intrapulmona...

journal_title：Critical care medicine

authors： Downs JB,Mitchell LA

更新日期：1976-11-01 00:00:00

abstract：OBJECTIVES:To validate scoring algorithm criteria established by the Japanese Association for Acute Medicine (JAAM) for disseminated intravascular coagulation (DIC) and to evaluate its diagnostic property by comparing the two leading scoring systems for DIC, from the Japanese Ministry of Health and Welfare (JMHW) and I...

journal_title：Critical care medicine

authors： Gando S,Iba T,Eguchi Y,Ohtomo Y,Okamoto K,Koseki K,Mayumi T,Murata A,Ikeda T,Ishikura H,Ueyama M,Ogura H,Kushimoto S,Saitoh D,Endo S,Shimazaki S,Japanese Association for Acute Medicine Disseminated Intravascular Coagulati

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Endotoxin (lipopolysaccharide [LPS]) has been associated with sepsis and the high mortality rate seen in septic shock. The administration of a small amount of LPS to healthy subjects produces a mild syndrome qualitatively similar to that seen in clinical sepsis. We used this model to test the efficacy of an ...

journal_title：Critical care medicine

authors： Bunnell E,Lynn M,Habet K,Neumann A,Perdomo CA,Friedhoff LT,Rogers SL,Parrillo JE

更新日期：2000-08-01 00:00:00