Activation-Associated Accelerated Apoptosis of Memory B Cells in Critically Ill Patients With Sepsis.

abstract：OBJECTIVES:To evaluate the effect of a part-time rapid response system on the occurrence rate of cardiopulmonary arrest by comparing the times of rapid response system operation versus nonoperation. DESIGN:Retrospective cohort study. SETTING:A 1,360-bed tertiary care hospital. PATIENTS:Adult patients admitted to the...

journal_title：Critical care medicine

authors： Kim Y,Lee DS,Min H,Choi YY,Lee EY,Song I,Park JS,Cho YJ,Jo YH,Yoon HI,Lee JH,Lee CT,Do SH,Lee YJ

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:To describe the current status and the clinical data related to the effects of tight glucose control by intensive insulin therapy in critically ill patients. DESIGN:Review article. SETTING:University hospital. PATIENTS:Medical and surgical critically ill patients in whom a correlation between blood glucose...

journal_title：Critical care medicine

authors： Preiser JC,Devos P

更新日期：2007-09-01 00:00:00

abstract：:The authors determined the correction factor (Ct) for three sizes of commonly available central venous catheters. These catheters are used as the injectate catheter when a 2.5 Fr transthoracic thermistor is used to determine cardiac output by thermodilution. The valves for Ct were highly reproducible. These determinat...

journal_title：Critical care medicine

authors： Baskoff JD,Maruschak GF

更新日期：1981-12-01 00:00:00

abstract：OBJECTIVES:The objectives of this article are to introduce and explore a novel paradigm based on complex nonlinear systems, and to evaluate its application to critical care research regarding the systemic host response and multiple organ dysfunction syndrome (MODS). DATA SOURCES:Published original work, review article...

journal_title：Critical care medicine

authors： Seely AJ,Christou NV

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVES:Acute hemolysis is associated with organ damage, inflammation, and impaired vascular function. Stimulation of the cholecystokinin-1 receptor-dependent vagal anti-inflammatory reflex with lipid-rich enteral nutrition was demonstrated to prevent tissue damage and attenuate inflammation. This study investigates...

journal_title：Critical care medicine

authors： de Haan JJ,Windsant IV,Lubbers T,Hanssen SJ,Hadfoune M,Prinzen FW,Greve JW,Buurman WA

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To compare the impact of two different customization strategies in the performance of the admission Mortality Probability Model II (MPM II0) using formal statistical assessment. DESIGN:Analysis of the database of a multicenter, multinational, prospective cohort study, EURICUS-1, involving 89 intensive care u...

journal_title：Critical care medicine

authors： Moreno R,Apolone G

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:To study the course of gastric regional PCO2 (PrCO2) in patients with cardiogenic shock requiring intra-aortic balloon (IAB) counterpulsation and the prognostic value of PrCO2 in this patient population. DESIGN:A prospective, observational clinical study. SETTING:Medical intensive care unit in a university ...

journal_title：Critical care medicine

authors： Janssens U,Graf J,Koch KC,vom Dahl J,Hanrath P

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVES:Streptococcus pneumoniae is the most common causative pathogen in community-acquired pneumonia. In patients, thrombocytopenia is correlated with an adverse outcome of pneumonia. Platelets can modulate the host response to infection in several ways, that is, by facilitating clot formation, production of antim...

journal_title：Critical care medicine

authors： van den Boogaard FE,Schouten M,de Stoppelaar SF,Roelofs JJ,Brands X,Schultz MJ,van't Veer C,van der Poll T

更新日期：2015-03-01 00:00:00

abstract：:The applicability of continuous arteriovenous hemofiltration (CAVH) for renal replacement therapy was evaluated in three infants and two young children with catastrophic medical and surgical illnesses. In the first four patients, CAVH was used in conjunction with either peritoneal or hemodialysis. In the fifth patient...

journal_title：Critical care medicine

authors： Leone MR,Jenkins RD,Golper TA,Alexander SR

更新日期：1986-12-01 00:00:00

abstract：OBJECTIVE:To review how endogenous protein C activation might change in disease states and to discuss the implications of these findings in the context of severe sepsis. DATA SOURCE:A review of the published literature in PubMed together with data from abstracts from 2001 to present. DATA EXTRACTION AND SYNTHESIS:Act...

journal_title：Critical care medicine

authors： Liaw PC

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVES:Light chains κ and λ are immunoglobulin constituents but also circulate independently in blood as free light chains. We investigated whether a concomitant abnormality in free light chain and immunoglobulin levels could identify a high risk of death sepsis subpopulation to inform future IV immunoglobulin tria...

journal_title：Critical care medicine

authors： Shankar-Hari M,Singer M,Spencer J

更新日期：2017-11-01 00:00:00

abstract：:The EEGs of 40 infants paralyzed with D-tubocurarine or pancuronium during the neonatal period were reviewed retrospectively. The 23 infants who survived were re-examined at 1-3 yr of age. Sixteen infants had normal or mildly abnormal EEGs in the neonatal period; 3 died of nonneurologic causes; the remainder were norm...

journal_title：Critical care medicine

authors： Tharp BR,Laboyrie PM

更新日期：1983-12-01 00:00:00

abstract：OBJECTIVES:During cardiopulmonary resuscitation (CPR), elimination of CO2 was shown to be limited by low tissue perfusion, especially when very low perfusion pressures were generated. It has therefore been suggested that sodium bicarbonate (NaHCO3), by producing CO2, might aggravate the hypercarbic component of the exi...

journal_title：Critical care medicine

authors： Bar-Joseph G,Weinberger T,Castel T,Bar-Joseph N,Laor A,Bursztein S,Ben Haim S

更新日期：1998-08-01 00:00:00

abstract：:Bradycardia is common in critical care units. It may be transient, asymptomatic and of little consequence, or life-threatening. Bradycardia may result from abnormalities of the sinus node, atrioventricular node, or the His-Purkinje system. It may also be precipitated by drug effects or enhanced vagal tone. Proper diag...

journal_title：Critical care medicine

authors： Kaushik V,Leon AR,Forrester JS Jr,Trohman RG

更新日期：2000-10-01 00:00:00

abstract：:An emergency cricothyrotomy device was placed in 11 anesthetized dogs in order to assess airway damage and problems in placement, ventilation, and design. Posterior airway perforation without esophageal damage occurred in three animals. Submucosal hematomas or cricoid cartilage injury occurred in seven animals. As pla...

journal_title：Critical care medicine

authors： Bjoraker DG,Kumar NB,Brown AC

更新日期：1987-02-01 00:00:00

abstract：:The acute effects of controlled O2 therapy on hemodynamics and blood gases were investigated in 22 patients with decompensated chronic obstructive pulmonary disease (COPD). An inspired O2 fraction (FIO2) of 0.24 and 0.28 given to the first 12 patients markedly improved arterial and mixed-venous blood oxygenation with ...

journal_title：Critical care medicine

authors： Lejeune P,Mols P,Naeije R,Hallemans R,Melot C

更新日期：1984-12-01 00:00:00

abstract：OBJECTIVE:To investigate the mechanism by which methylprednisolone protects the liver from hypoxia-induced injury. DESIGN:Prospective control study using the isolated rat liver. SETTING:Animal research facility. SUBJECTS:Male, fasted, pathogen-free Sprague-Dawley rats. INTERVENTIONS:Low-flow hypoxia was produced by...

journal_title：Critical care medicine

authors： Motoyama S,Saito S,Minamiya Y,Saito R,Nakamura M,Okuyama M,Imano H,Ogawa J

更新日期：2003-05-01 00:00:00

abstract：:Oral amiodarone's slow absorption handicaps rapid treatment of life-threatening arrhythmias. We used iv amiodarone to treat ten patients with hemodynamically significant atrial arrhythmias and life-threatening ventricular arrhythmias refractory to all conventional medical treatment. Arrhythmias were controlled in nine...

journal_title：Critical care medicine

authors： Alves LE,Rose EP,Cahill TB Jr

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVES:To examine whether niacin attenuates lung inflammation and improves survival during sepsis and to determine whether the beneficial effects of niacin are associated with downregulation of the nuclear factor (NF)-κB pathway. DESIGN:Prospective laboratory study. SETTING:University laboratory. SUBJECTS:Male S...

journal_title：Critical care medicine

authors： Kwon WY,Suh GJ,Kim KS,Kwak YH

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to quantify the effect of hypertonic saline solution on contused and noncontused brain tissue in patients with traumatic brain injury. We hypothesize that hypertonic saline would increase the volume of brain contusion while decreasing the volume of noncontused hemispheric areas. DES...

journal_title：Critical care medicine

authors： Lescot T,Degos V,Zouaoui A,Préteux F,Coriat P,Puybasset L

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of, the risk factors associated with, and the outcome of tracheostomy in a heterogeneous population of mechanically ventilated patients. DESIGN:Prospective, observational cohort study. SETTING:A total of 361 intensive care units from 12 countries. PATIENTS:A cohort of 5,081 patie...

journal_title：Critical care medicine

authors： Frutos-Vivar F,Esteban A,Apezteguía C,Anzueto A,Nightingale P,González M,Soto L,Rodrigo C,Raad J,David CM,Matamis D,D' Empaire G,International Mechanical Ventilation Study Group.

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:To determine the proportion of patients with documented bacterial aspiration pneumonia among comatose ICU patients with symptoms suggesting either bacterial aspiration pneumonia or non-bacterial aspiration pneumonitis. DESIGN:Prospective observational study. SETTING:University-affiliated 30-bed ICU. PATIE...

journal_title：Critical care medicine

authors： Lascarrou JB,Lissonde F,Le Thuaut A,Bachoumas K,Colin G,Henry Lagarrigue M,Vinatier I,Fiancette M,Lacherade JC,Yehia A,Joret A,Lebert C,Bourdon S,Martin Lefèvre L,Reignier J

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:Studies have shown that endothelium-dependent relaxation (mediated by endothelium-derived nitric oxide) is depressed during the early, hyperdynamic stage of sepsis. Although it is known that ATP-MgCl2 produces beneficial effects following various adverse circulatory conditions, it remains unknown whether thi...

journal_title：Critical care medicine

authors： Wang P,Ba ZF,Cioffi WG,Bland KI,Chaudry IH

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND AND METHODS:We postulated that low-dose heparin (10 IU/kg.hr) administered as a continuous iv infusion may prevent or ameliorate the induction of thrombin-induced disseminated intravascular coagulation in baboons under general anesthesia. In a nonrandomized experiment lasting 8 hrs, animals were divided into...

journal_title：Critical care medicine

authors： du Toit HJ,Coetzee AR,Chalton DO

更新日期：1991-09-01 00:00:00

abstract：OBJECTIVE:The benefit of continuous on-site presence by a staff academic critical care specialist in the intensive care unit of a teaching hospital is not known. We compared the quality of care and patient/family and provider satisfaction before and after changing the staffing model from on-demand to continuous 24-hr c...

journal_title：Critical care medicine

authors： Gajic O,Afessa B,Hanson AC,Krpata T,Yilmaz M,Mohamed SF,Rabatin JT,Evenson LK,Aksamit TR,Peters SG,Hubmayr RD,Wylam ME

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:Our objective was to quantify the association between intensive care unit-acquired dysglycemia (hyperglycemia, hypoglycemia, and high variability) and in-hospital mortality. DESIGN:Retrospective, observational study. SETTING:eICU Research Institute participating hospitals with an active tele-ICU program bet...

journal_title：Critical care medicine

authors： Badawi O,Waite MD,Fuhrman SA,Zuckerman IH

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Acute lung injury with subsequent pneumonia and sepsis represents a major cause of morbidity and mortality in thermally injured patients. Production of nitric oxide by the neuronal and inducible nitric oxide synthase may be critically involved in the pathophysiology of the disease process at different time po...

journal_title：Critical care medicine

authors： Lange M,Connelly R,Traber DL,Hamahata A,Cox RA,Nakano Y,Bansal K,Esechie A,von Borzyskowski S,Jonkam C,Traber LD,Hawkins HK,Herndon DN,Enkhbaatar P

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:Intravesical pressure measurement is considered to be the gold standard for the assessment of intra-abdominal pressure. However, this method is indirect and depends on a physiologic bladder function. We evaluated a modified piezoresistive technique and a water-capsule technique for direct and continuous intra...

journal_title：Critical care medicine

authors： Schachtrupp A,Henzler D,Orfao S,Schaefer W,Schwab R,Becker P,Schumpelick V

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:Neutropenia recovery may be associated with an increased risk of respiratory function deterioration. A history of pneumonia complicating neutropenia has been identified as the leading cause of adult respiratory distress syndrome during neutropenia recovery in patients receiving anticancer chemotherapy, sugges...

journal_title：Critical care medicine

authors： Azoulay E,Attalah H,Yang K,Herigault S,Jouault H,Brun-Buisson C,Brochard L,Harf A,Schlemmer B,Delclaux C

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To develop practice parameters for the evaluation of adult patients who develop a new fever in the intensive care unit (ICU) for the purpose of guiding clinical practice. PARTICIPANTS:A task force of 13 experts in disciplines related to critical care medicine, infectious diseases, and surgery was convened fr...

journal_title：Critical care medicine

authors： O'Grady NP,Barie PS,Bartlett J,Bleck T,Garvey G,Jacobi J,Linden P,Maki DG,Nam M,Pasculle W,Pasquale MD,Tribett DL,Masur H

更新日期：1998-02-01 00:00:00