Abstract:
PURPOSE:We determined the prevalence of risk factors for the development of acute respiratory distress syndrome (ARDS), outcomes of critical illness, and the impact of highly active antiretroviral therapy in HIV-1-infected patients. We hypothesized that in an urban county hospital, HIV-1-infected patients with ARDS would have a higher mortality than their HIV-1-uninfected counterparts. MATERIALS AND METHODS:Subjects were enrolled between 2006 and 2012. Baseline patient demographics, comorbidities, illness severity, causes of ARDS, and clinical outcomes were obtained. The primary end point was hospital mortality. RESULTS:A total of 178 subjects with ARDS were enrolled in the study; 40 (22%) were infected with HIV-1. The median CD4 count was 75 (15.3-198.3), and 25% were on highly active antiretroviral therapy. HIV-1-infected subjects were significantly younger (44 vs 52 years; P < .01) and had higher rates of asthma, chronic obstructive pulmonary disease, pneumonia, history of hospital-acquired infections, and prior sepsis. HIV-1-infected subjects had greater illness severity by Acute Physiology and Chronic Health Evaluation II scores (29 [24-31] vs 24 [22-25]; P < .01). Hospital mortality was not higher among HIV-1-infected subjects compared with HIV-1-uninfected subjects (50.0% vs 38.4%; P = .19). CONCLUSIONS:In patients with ARDS, HIV-1 infection was associated with greater illness severity but was not associated with higher mortality in ARDS. Future studies need to be done to evaluate the factors that contribute to high morbidity and mortality in medically vulnerable populations who develop ARDS.
journal_name
J Crit Carejournal_title
Journal of critical careauthors
Nirappil FJ,Maheshwari A,Andrews J,Martin GS,Esper AM,Cribbs SKdoi
10.1016/j.jcrc.2014.10.020subject
Has Abstractpub_date
2015-02-01 00:00:00pages
60-4issue
1eissn
0883-9441issn
1557-8615pii
S0883-9441(14)00427-4journal_volume
30pub_type
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journal_title:Journal of critical care
pub_type: 杂志文章,随机对照试验
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更新日期:2017-08-01 00:00:00
abstract:PURPOSE:Data regarding outcome of patients with chronic liver disease with severe hepatic encephalopathy in intensive care unit are currently scarce. METHODS:This study is a retrospective observational case series in a medical intensive care unit (ICU) in a university hospital from 1995 to 2005. Patients with hepatic ...
journal_title:Journal of critical care
pub_type: 杂志文章
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journal_title:Journal of critical care
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更新日期:2015-02-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章,评审
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更新日期:2017-12-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章,多中心研究
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journal_title:Journal of critical care
pub_type: 杂志文章,随机对照试验
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更新日期:2012-12-01 00:00:00
abstract:PURPOSE:To evaluate the role of plasma disappearance rate of indocyanine green (PDR-ICG) as an outcome prediction tool in cardiac surgery. PATIENTS AND METHODS:One hundred ninety patients undergoing coronary artery bypass grafting, valve surgery or combined procedures were enrolled. PDR-ICG measurements along with sta...
journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2013.10.023
更新日期:2014-04-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2009.05.011
更新日期:2010-06-01 00:00:00
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journal_title:Journal of critical care
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更新日期:2018-04-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
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更新日期:2020-04-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2017.06.020
更新日期:2017-12-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2015.03.014
更新日期:2015-08-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
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更新日期:2017-06-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2016.02.016
更新日期:2016-06-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2020.06.014
更新日期:2020-10-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2013.05.017
更新日期:2013-12-01 00:00:00
abstract:PURPOSE:The purpose of study was to evaluate the clinical results of early stabilization of spine fractures in polytrauma patients. MATERIALS AND METHODS:Between August 2003, and May 2012, 166 polytrauma patients with thoracolumbar spine fractures were included. Patients were divided into 2 groups according to injury-...
journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2014.03.003
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Quality improvement (QI) is a central tenant of trauma center accreditation in most countries, but its effectiveness is largely unknown. We sought to explore opportunities for improving trauma QI. METHODS:We performed a qualitative research study using grounded theory analyses of interviews with medical dir...
journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2012.07.010
更新日期:2012-12-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1053/jcrc.2001.25470
更新日期:2001-06-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2016.10.008
更新日期:2017-04-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jcrc.2018.07.020
更新日期:2018-12-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jcrc.2019.08.021
更新日期:2019-12-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2014.07.001
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Changes in mean perfusion pressure (MPP) from premorbid resting values may contribute to the progression of septic acute kidney injury (AKI). OBJECTIVES:In patients with septic shock, we aimed to investigate the association of changes from premorbid values with AKI severity and progression. METHODS:We obta...
journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2015.05.003
更新日期:2015-10-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2017.04.033
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Thromboelastometry/elastography (ROTEM/TEG) showed promising results for diagnosis of sepsis-induced coagulopathy, but their association with the outcome is unclear. Our aim was to assess any difference in ROTEM/TEG measurements between septic survivors and non-survivors. METHODS:Pubmed, Web of Science, Emb...
journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2020.09.034
更新日期:2021-02-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2015.10.013
更新日期:2016-02-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章,评审
doi:10.1016/j.jcrc.2017.08.010
更新日期:2017-12-01 00:00:00
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journal_title:Journal of critical care
pub_type: 评论,信件
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更新日期:2017-06-01 00:00:00