Does coronary calcium scoring with a SCORE better predict significant coronary artery stenosis than without? Correlation with computed tomography coronary angiography.

Abstract:

OBJECTIVE:To determine effectiveness of coronary artery calcium score (CACS) alone and combined with Systematic Coronary Risk Evaluation (SCORE) in adult patients for significant coronary artery stenosis by using computed tomography coronary angiography (CTCA) as reference standard. METHODS:Two thousand twenty-one patients with suspected coronary artery disease (CAD) underwent CACS test and CTCA. Patients were examined with dual-source CT and were grouped according to their age, gender, CACS, and estimated SCORE risk. Coronary plaque existence and degree of stenosis were assessed with CTCA. Sensitivity, specificity, and ROC curves were analyzed. RESULTS:CACS was the single independent variable in estimating relative risk of critical stenosis and had superior outcome when compared with SCORE risk in logistic regression and ROC curve. Area under the ROC curve was greatest in the interval between 50-59 years. When SCORE was combined with CACS in patients with zero CACS, percentage of significant stenosis increased from 1.4% to 7.0% in patients with high or very high SCORE risk, and decreased to 0.9 % in patients with low or moderate SCORE risk. CONCLUSIONS:CACS combination with SCORE risk predicts coronary artery stenosis. When CACS is zero, CTCA can be performed in patients with high or very high SCORE risk.

journal_name

Eur Radiol

journal_title

European radiology

authors

Durhan G,Hazırolan T,Sunman H,Karakaya J,Karçaaltıncaba M,Aytemir K,Karaağaoğlu E,Akata D

doi

10.1007/s00330-014-3477-2

subject

Has Abstract

pub_date

2015-03-01 00:00:00

pages

776-84

issue

3

eissn

0938-7994

issn

1432-1084

journal_volume

25

pub_type

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