Abstract：
OBJECTIVES:To verify the association between EGFR status and clinical response to microwave ablation (MWA) and survival. METHODS:NSCLC patients with known EGFR status and treated with MWA in combination with chemotherapy were retrospectively enrolled in the study. RESULTS:A total of 61 patients were recruited. EGFR mutations were found in 28 patients (39.4 %), and were more common in women (67.7 %) and nonsmokers (74.1 %). Complete ablation was achieved in 69.7 % of patients with EGFR mutant tumours and in 82.1 % of patients with EGFR wild-type tumours (p = 0.216). The median progression-free survival (PFS) and overall survival (OS) were 8.3 months and 27.2 months in patients with an EGFR mutant tumour. The corresponding values were 5.4 months (p = 0.162) and 17.8 months (p = 0.209) in patients with an EGFR wild-type tumour. Patients with complete ablation had longer PFS (7.8 months vs. 4.2 months, p = 0.024) and OS (28.1 months vs. 12.6 months, p = 0.001) than those with incomplete ablation. Multivariate analyses also showed that response to MWA was an independent prognostic factor for OS, but EGFR status was not, and that neither response to MWA nor EGFR status was a prognostic factor for PFS. CONCLUSIONS:The EGFR status was not related to response to MWA, and response to MWA was a predictor of survival. KEY POINTS:• EGFR mutations were commonly seen in women and in nonsmokers • EGFR status had no correlation with the response to MWA, PFS and OS. • The response to MWA could predict PFS and OS.
journal_name
Eur Radioljournal_title
European radiologyauthors
Wei Z,Ye X,Yang X,Huang G,Li W,Wang J,Han X,Meng M,Ni Ydoi
10.1007/s00330-016-4474-4subject
Has Abstractpub_date
2017-04-01 00:00:00pages
1685-1694issue
4eissn
0938-7994issn
1432-1084pii
10.1007/s00330-016-4474-4journal_volume
27pub_type
杂志文章abstract：OBJECTIVE:To investigate dual-energy CT of hypervascular liver lesions in patients with HCC. METHODS:Forty patients with hepatocellular carcinomas were investigated with abdominal dual-energy CT. In each patient unenhanced and contrast-enhanced imaging with arterial und portovenous delay were performed. Hypervascular ...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-010-1964-7
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVES:To compare the scan acquisition time, radiation dose, subjective and objective image quality of two dual-source CT scanners (DSCT) for detection of acute pulmonary embolism. METHODS:Two hundred twenty-one scans performed on the 2nd-generation DSCT and 354 scans on the 3rd-generation DSCT were included in th...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-019-06650-6
更新日期：2020-05-01 00:00:00
abstract：:Ultrasonography (US) is the most commonly used liver imaging modality worldwide. Unfortunately, it has limited sensitivity in the detection of small tumor nodules. Moreover, US findings are often nonspecific, as appearances of benign and malignant liver lesions overlap. The introduction of microbubble contrast agents ...
journal_title：European radiology
pub_type： 杂志文章,评审
doi：10.1007/s10406-007-0231-8
更新日期：2007-12-01 00:00:00
abstract：:The purpose of this study was to describe and characterize the MR imaging findings in a group of patients who underwent surgery for adhesive capsulitis. Twenty-four MR imaging studies in 24 consecutive patients with clinical evidence of adhesive capsulitis were performed prior to arthroscopic capsulotomy. There were 1...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-002-1349-7
更新日期：2002-08-01 00:00:00
abstract：OBJECTIVES:To investigate the feasibility of a newly developed noise reduction technique at coronary CT angiography (CTA) that uses multi-phase data-averaging and non-rigid image registration. METHODS:Sixty-five patients underwent coronary CTA with prospective ECG-triggering. The range of the phase window was set at 7...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-014-3381-9
更新日期：2015-01-01 00:00:00
abstract：:The purpose of the present study was to evaluate the usefulness of a new gray-scale test pattern (NGTP) that was developed to easily adjust the gradients of thoracic CT imaging and enable visual consistency. The Society of Motion Picture and Television Engineers (SMPTE) pattern and the NGTP were used for comparison. T...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-004-2315-3
更新日期：2004-12-01 00:00:00
abstract：OBJECTIVE:To describe and evaluate a novel technical development to improve detection of intracranial vessel occlusions using multiphase CT angiography (MPCTA). MATERIALS AND METHODS:The institutional ethics committee approved the study. Fifty patients (30 consecutive distal (M2 or smaller) anterior circulation occlus...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-017-5124-1
更新日期：2018-04-01 00:00:00
abstract：:The purpose of this study was to assess the performance of a new motion correction algorithm. Twenty-five dynamic MR mammography (MRM) data sets and 25 contrast-enhanced three-dimensional peripheral MR angiographic (MRA) data sets which were affected by patient motion of varying severeness were selected retrospectivel...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-006-0224-3
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:To develop and validate a volume-based, quantitative imaging marker by integrating multi-parametric MR images for predicting glioblastoma survival, and to investigate its relationship and synergy with molecular characteristics. METHODS:We retrospectively analysed 108 patients with primary glioblastoma. The d...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-017-4751-x
更新日期：2017-09-01 00:00:00
abstract：:Vertebral fractures are the hallmark of osteoporosis and are associated with increased morbility and mortality. Because a majority of vertebral fractures often occur in absence of specific trauma and are asymptomatic, their identification is radiographic. The two most widely used methods to determine the severity of v...
journal_title：European radiology
pub_type： 杂志文章,评审
doi：10.1007/s00330-008-0899-8
更新日期：2008-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the integrity of endometrial enhancement after magnetic resonance imaging-guided high-intensity focused ultrasound (MR-HIFU) ablation of submucosal uterine fibroids based on contrast-enhanced MRI findings, and to identify the risk factors for endometrial impairment. METHODS:In total, 117 submucos...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-017-4765-4
更新日期：2017-09-01 00:00:00
abstract：BACKGROUND:Hypersensitivity pneumonitis (HP) has a variable clinical course. Modelling of quantitative CALIPER-derived CT data can identify distinct disease phenotypes. Mortality prediction using CALIPER analysis was compared to the interstitial lung disease gender, age, physiology (ILD-GAP) outcome model. METHODS:CAL...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-016-4697-4
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVES:To determine the integrative value of contrast-enhanced computed tomography (CECT), transcriptomics data and clinicopathological data for predicting the survival of bladder urothelial carcinoma (BLCA) patients. METHODS:RNA sequencing data, radiomics features and clinical parameters of 62 BLCA patients were ...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-019-06371-w
更新日期：2020-01-01 00:00:00
abstract：OBJECTIVES:To compare software estimates of volumetric breast density (VBD) based on breast tomosynthesis (BT) projections to those based on digital mammography (DM) images in a large screening cohort, the Malmö Breast Tomosynthesis Screening Trial (MBTST). METHODS:DM and BT images of 9909 women (enrolled 2010-2015) w...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-018-5582-0
更新日期：2019-01-01 00:00:00
abstract：:The imaging findings that ultrasonographically differentiate focal acute pancreatitis (FAP) from a malignant lesion of the pancreas are described. Focal acute pancreatitis is ultrasonographically (US) characterized as a hypoechoic, homogeneous, localized, subsegmental, non-expansive and diffusely demarcated lesion loc...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s003300050756
更新日期：1999-01-01 00:00:00
abstract：:Contrast-enhanced MRI (CE-MRI) of the breast has been investigated for over 10 years. The reports of sensitivity for cancer detection have generally been greater than 90 %. However, estimates of specificity have varied greatly. Differing results are due to differences in study populations, technical methods and criter...
journal_title：European radiology
pub_type： 杂志文章,评审
doi：10.1007/pl00006909
更新日期：1997-01-01 00:00:00
abstract：OBJECTIVES:To assess changes in portal and splanchnic arterial haemodynamics in patients undergoing transjugular intrahepatic portosystemic shunt (TIPS) using four-dimensional (4D) flow MRI, a non-invasive, non-contrast imaging technique. METHODS:Eleven patients undergoing TIPS implantation were enrolled. K-t GRAPPA a...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-015-3663-x
更新日期：2015-09-01 00:00:00
abstract：:Mesodermal tumors of the urinary bladder are rare and the majority of them are malignant. We report a case of an intramural leiomyoma of the bladder presenting with symptoms of a mild lower urinary tract infection. The patient was managed with partial cystectomy and the outcome was excellent. ...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s003300051034
更新日期：2000-01-01 00:00:00
abstract：AIM:To describe the effect of hepatobiliary-specific MR imaging contrast agent (HBCA) administration on the signal intensity of peritoneal and pleural fluid effusions on T1-weighted MR images. MATERIALS AND METHODS:From October 2015 to May 2016 139 patients (mean 60±10 years old, 69 % males) with peritoneal or pleural...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-017-5261-6
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVES:To assess the accuracy of MRI-derived liver surface nodularity (LSN) score for staging of hepatic fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). METHODS:Forty-seven patients with clinicopathological diagnosis of NAFLD who underwent 1.5-T liver MRI within 12 months of liver biopsy were ...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-020-07114-y
更新日期：2021-01-01 00:00:00
abstract：:The aim of this study was to assess the capability of a 3D isotropic MRI T2-weighted sequence (3D T2 ISO) in the depiction of changes of neurovascular bundles (NVBs) after bilateral nerve-sparing radical retropubic prostatectomy (RRP). Furthermore, our aim was also to introduce a new MRI classification score of the NV...
journal_title：European radiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00330-008-1102-y
更新日期：2009-01-01 00:00:00
abstract：:We retrospectively reviewed surgical biopsy findings of lesions diagnosed as radial scars (RS) at stereotactic core-needle biopsy (SCNB). RS was diagnosed in 52 of 1415 (3.7%) consecutive mammographically detected lesions that underwent 14-gauge automated SCNB. Subsequent surgical biopsy findings were available for 43...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-006-0196-3
更新日期：2006-08-01 00:00:00
abstract：:CT-guided procedures remain an important tool for diagnosis and tissue acquisition for primary diagnosis and molecular/tissue correlation. New imaging devices such as MDCT and PET/CT will improve diagnosis but percutaneous procedures will be needed to confirm and support new molecular and DNA treatments. Coagulopathic...
journal_title：European radiology
pub_type： 杂志文章,评审
doi：10.1007/s10406-005-0130-9
更新日期：2005-11-01 00:00:00
abstract：:We report a case of alveolar soft part sarcoma (ASPS) of the thigh with lung metastases in a 22-year-old woman. The findings of digital subtraction angiography (DSA) and MRI contributed to the diagnosis of ASPS. Especially dynamic contrast-enhanced MRI was useful for evaluating the effect of chemoembolotherapy. ...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s003300050477
更新日期：1998-01-01 00:00:00
abstract：OBJECTIVES:To investigate the morphological classification of intraductal papillary neoplasm of the bile duct (IPNB), as well as morphological differences between IPNB without mucin secretion (IPNB-NM) and IPNB with mucin secretion (IPMN-B). METHODS:Eighty-one patients with IPNB were retrospectively analysed. Imaging ...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-017-5123-2
更新日期：2018-04-01 00:00:00
abstract：:Lung tumour ablation with a thin-calibre laser applicator system was evaluated. We quantified feasibility, technical success and complication rates in relation to lesion diameter and location. Forty-two patients with 64 lung tumours were treated (39 patients with metastases and three with primary tumours). Mean follow...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-006-0171-z
更新日期：2006-08-01 00:00:00
abstract：:We examined 20 prediagnostic CTs from 16 patients for whom the diagnosis of pancreatic cancer was delayed until full diagnostic CT was performed. Three radiologists independently reviewed the prediagnostic CTs along with 50 CTs of control subjects, including patients without pancreatic disease (n = 38) or with chronic...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-009-1422-6
更新日期：2009-10-01 00:00:00
abstract：OBJECTIVES:The study aims were to identify CT features that predict outcome of fibrotic idiopathic interstitial pneumonia (IIP) when information from lung biopsy data is unavailable. METHODS:HRCTs of 146 consecutive patients presenting with fibrotic IIP were studied. Visual estimates were made of the extent of abnorma...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-011-2098-2
更新日期：2011-08-01 00:00:00
abstract：OBJECTIVES:To assess whether using the Tree flowchart obviates unnecessary magnetic resonance imaging (MRI)-guided biopsies in breast lesions only visible on MRI. METHODS:This retrospective IRB-approved study evaluated consecutive suspicious (BI-RADS 4) breast lesions only visible on MRI that were referred to our inst...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-017-4755-6
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVES:Our aim was to investigate regional difference in brain activities in response to antiepileptic drug (AED) medications in benign epilepsy with central-temporal spikes (BECTS) using resting-state functional magnetic resonance imaging (fMRI). METHODS:Fifty-seven patients with BECTS underwent resting-state fMR...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-016-4531-z
更新日期：2017-05-01 00:00:00
