Abstract:
:Serial myoglobin determinations were made in 20 neonates during the first week of life to determine whether birth asphyxia results in ischemic damage to muscle with the subsequent pathologic release of myoglobin. Serum myoglobin values were significantly elevated in asphyxiated infants compared with control infants. High myoglobin values correlated with a longer duration of oliguria in the neonatal intensive care unit population. The value of urine dipstick testing for myoglobinuria screening was also evaluated. Infants with elevated myoglobin values were more likely to have a strongly positive urine dipstick for occult blood in the first 48 hours of life. These data suggest that ischemic damage to muscle with pathologic release of myoglobin occurs in the neonatal period and that urine dipstick testing provides a reasonable screening examination for myoglobinuria.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Kasik JW,Leuschen MP,Bolam DL,Nelson RMsubject
Has Abstractpub_date
1985-08-01 00:00:00pages
255-8issue
2eissn
0031-4005issn
1098-4275journal_volume
76pub_type
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