Pancreatic cancer: unreliability of frozen section in diagnosis.

Abstract:

:Thirty-two patients with a resectable mass in the head of the pancreas had pancreaticoduodenectomy for suspected or proven cancer. Twenty-eight proved to have cancer (15 periampullary and 13 pancreatic), and four had pancreatitis. The five-year survival for periampullary and pancreatic cancer was 25% and 0%, respectively. The operative mortality was 19%. There were no false-positive frozen section diagnoses. Seventy-five percent with negative frozen section proved to have cancer, of which 17% were five-year survivors. Surgical judgment based on clinical findings may be more reliable than a negative frozen section in the diagnosis of suspected malignancy. Pancreaticoduodenectomy can be done on the basis of clinical judgment when no tumor is seen on frozen section of a mass in the head of the pancreas.

journal_name

South Med J

journal_title

Southern medical journal

authors

Harris PL,Rumley TO,Lineaweaver WC,Copeland EM 3rd

doi

10.1097/00007611-198509000-00007

subject

Has Abstract

pub_date

1985-09-01 00:00:00

pages

1053-6

issue

9

eissn

0038-4348

issn

1541-8243

journal_volume

78

pub_type

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