Abstract：
:In three patients with multiple myeloma, stage IIIA, a complete remission lasting from 6 to 8 years was attained, in spite of the fact that not all of them received treatment. In the latter case the remission lasted from 5 to 6 years. One of the patients had diffuse Gk + BIk myeloma, one presented with multiple focal one with protein BIk production, and one patient had multiple focal myeloma with spinal cord compression and complete lower paraplegia without verified secretion of monoclonal immunoglobulin. The times of therapy until the attainment of a complete remission were 3,5 and 13 years, whereas the total survival amounted to 9, 5 and 20 years since the appearance of the first disease symptoms. Sarcolysine was employed as the basic cytostatic agent in all the cases. Annual control examinations of the patients in a state of remission have not revealed any signs of myeloma. One patient is manifesting osteolytic deficiencies, however biopsy withdrawn from the focus of osteolysis have not shown any tumor. Immunochemical assay of serum and urine has failed to detect paraprotein, blood immunoglobulins have been discovered to be within normal. The author analyses 4 similar cases reported in literature. It is assumed that it would be premature to regard the patients described above as completely recovered from the biological standpoint and that it would be more wise to consider such cases as prolonged and fairly profound remissions.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Andreeva NEsubject
Has Abstractpub_date
1985-01-01 00:00:00pages
7-10issue
7eissn
0040-3660issn
2309-5342journal_volume
57pub_type
杂志文章abstract：:A study of the indices of iron metabolism in 29 patients with hereditary hemorrhagic telangiectasia revealed a decrease in the level of serum iron, an increase in serum latent and total iron-binding capacity values. The level of blood transferrin studied by radial immunodiffusion was elevated. The level of ferritin in...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：AIM:To compare a short-term hypotensive effect of intranasal ventilation with continuous positive airway pressure (CPAP-therapy) in patients with arterial hypertension stage I and placebo-control patients. MATERIAL AND METHODS:The CPAP-therapy and placebo-control groups consisted of 12 young men with arterial hyperten...
journal_title：Terapevticheskii arkhiv
pub_type： 临床试验,杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：AIM:To study changes in left atrial volume, geometry and function in myocardial infarction (MI) patients treated with beta-adrenoblocker and ACE inhibitor. MATERIAL AND METHODS:65 patients with Q-wave myocardial infarction (MI) were followed up for 6 months. Regular check-ups included clinical examination, ECG, echo-C...
journal_title：Terapevticheskii arkhiv
pub_type： 临床试验,杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:The results of intracoronary thrombolytic therapy with avelysine given to 21 patients with acute myocardial infarction are described. Intracoronary thrombolysis was performed on the average 5 h and 30 min after myocardial infarction onset. Recanalization of the coronary artery was attained in 16 patients, with no leth...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：AIM:To study causes and sequelae of intradialysis hypotension (IH) in patients with terminal renal failure (TRF). MATERIAL AND METHODS:Forty one patients with TRF on chronic hemodialysis (CH) were divided into two groups. The study group consisted of 24 patients with episodes of IH. Seventeen patients of the control g...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:The authors relate the results of 10 years of observations of 113 patients suffering from gluten enteropathy (GE) of the adults. In all the patients, the diagnosis was supported by the presence of hyper-regenerative atrophy of the small intestinal mucosa (total in 70% and subtotal in 30%). Metabolic disorders and cell...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：AIM:To investigate verbal dyspnea characteristics in patients with bronchial asthma (BA) and hyperventilation syndrome (HVS). MATERIAL AND METHODS:The trial covered 52 patients with BA, 10 patients with BA combination with HVS and 18 patients with HVS. Verbal dyspnea characteristics were studied with PM. Simon questio...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：AIM:To characterize hypertensive patients, residents of Moscow, treated at Moscow Municipal Cardiological Center (MMCC) in 1999. MATERIAL AND METHODS:A total of 1056 case histories of patients with the diagnosis of arterial hypertension or essential hypertension, directed to MMCC in 1999, were analyzed. The files were...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：AIM:To ascertain regularities of development of cellular immunity in patients with Astrakhan fever (AF) with reference to AF severity, treatment and course. MATERIAL AND METHODS:Cellular factors of immunity--relative and absolute contents of T-lymphocytes (early and late), T-helpers and T-suppressors, B-lymphocytes, n...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：AIM:to study the prevalence, pattern of and trends in affective disorders (AD) in patients with acute myocardial infarction (AMI) and to assess whether they might be corrected with the antidepressant tianeptin. SUBJECTS AND METHODS:The study enrolled 108 patients with AMI. To detect and evaluate affective spectrum dis...
journal_title：Terapevticheskii arkhiv
pub_type： 临床试验,杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：AIM:To evaluate alterations in the immune system (IS) in patients with different forms of secondary immunodeficiency and design of differentiated programs of reestablishment of defective functions depending on pathogenetically important type of deficiency of immunocompetent cells. MATERIALS AND METHODS:Clinicoimmunolo...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:Echocardiographic alterations were compared with the clinical picture in 32 patients with different forms of hereditary spinocerebellar degenerations (HSCD). Three groups of patients were examined. Group I included patients with Friedreich's ataxia (FA), group II consisted of patients with familial cerebellar degenera...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：AIM:To devise the technique and evaluate the efficacy of videothoracoscopic collagen pleurodesis (VCP) in malignant pleural exudates (MPE). MATERIAL AND METHODS:VCP was performed in 24 patients with recurrent MPE. 20 patients were diagnosed to have non-small-cell cancer of the lung, 4 patients--breast cancer. The oper...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2004-01-01 00:00:00
abstract：AIM:To study markers of myocardial electrical instability in patients with coronary heart disease (CHD) during silent myocardial ischemic episodes. SUBJECTS AND METHODS:Eighty-two patients with stable CHD (mean age 62.6 +/- 5.4 years) were examined. In addition to standard physical examination, a complex of their stud...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:The most important condition for effective prophylactic medical examination is early detection of diseases. The efficacy of prophylactic medical examination of rheumatic fever patients rises considerably under the conditions of stage-by-stage therapy. Another important condition for early detection and diagnosis is ra...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:Diphtheria morbidity among adult population of Moscow is growing. The tests of different modes and schemes of heterogeneous antidiphtheria serum administration have found out that the highest efficacy of serotherapy was achieved with a single intravenous dose. Another treatment of diphtheria is hemosorption. Widely us...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：AIM:To characterize correlations between the levels of vitamin D, parathormone, calcium, blood phosphates in patients with different stages of chronic disease of the kidney (CDK) given no therapy replacing renal function (TRRF). MATERIAL AND METHODS:Serum levels of creatinine, electrolytes, parathormone (PTH), 25(OH)-...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:Blood plasma free radical lipid oxidation was studied in 98 patients with acute dysentery (AD) and 64 patients with food toxinfection (FTI). Free radical lipid oxidation was assessed by the intensity of chemiluminescence and the level of lipid peroxides. Activation of blood plasma lipid peroxidation was established wi...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：:Arteparon was locally used in 87 patients after reconstructive surgery on the joints. Arteparon administration was conducted 2 weeks following corrective operations: arthrotomy, allo- and autoplasty, replantation of the limb segments, arthroplasty, one-pole endoprosthesis. The drug was introduced into the hip, knee, a...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：AIM:To characterize a group of patients with follicular lymphoma (FL) with leukemization and to evaluate the efficiency of different therapy options (R-CHOP/R-FMC/high-dose chemotherapy (HDCT)). SUBJECTS AND METHODS:18 (7.2%) out of 250 patients diagnosed with FL, who were examined and treated at the National Research...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.17116/terarkh201789745-50
更新日期：2017-01-01 00:00:00
abstract：AIM:To study morphofunctional peculiarities of gastric mucosa in native and migrant rural population of North Siberia. MATERIAL AND METHODS:A comprehensive clinicomorphological examination including physical examination, ultrasonic scanning, cholecystography, duodenal intubation, intragastric pH-metry, esophagogastrod...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:The authors describe the status of lipid peroxidation (diene conjugates and malonic dialdehyde) and the endogenous antioxidant enzyme superoxide dismutase in the course of the treatment of patients with acute focal pneumonia by means of the use of transthoracic intrapulmonary injections of unithiol and autologous ultr...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:Forty patients aged 33 to 66 years suffering from chronic alcoholism, stages II-III, were examined. All the patients were subjected to contrast ventriculography before and after exercise test to identify the latent forms of heart failure. According to the coronarography findings, 9 out of the 40 patients demonstrated ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:The paper discusses the pathogenesis of urinary tract infections, the mechanisms of resistance in their pathogens to antimicrobials and uroseptics, and approaches to defining patient management tactics. :В статье обсуждается патогенез инфекций мочевых путей, механизмы формирования устойчивости их возбудителей к антиб...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,评审
doi：10.17116/terarkh20158711123-133
更新日期：2015-01-01 00:00:00
abstract：AIM:To study the association of adiponectin gene G276Т (ADIPOQ) polymorphism with the development of metabolic syndrome (MS) in ethnic Kyrgyz patients. MATERIAL AND METHODS:A total of 171 patients with MS (a study group) and 117 patients without MS (a comparison group) were examined. MS was defined on the basis of the...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.17116/terarkh2015871085-90
更新日期：2015-01-01 00:00:00
abstract：:A study was made of immunologic cell markers in 32 patients with acute myeloid leukemia by indirect immunofluorescence with the aid of xenogeneic antisera and monoclonal antibodies obtained by the authors. Ia-like antigen demonstrated by monoclonal antisera IKO-I expressed in myeloblastic leukemia with maturation in m...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：AIM:To study clinical features of typhoid fever (TF) in migrants (subjects in military service in Tadjikistan). MATERIAL AND METHODS:In chronic water epidemic TF symptoms were studied in 547 young soldiers and officers serving in Tadjikistan with incomplete biological and/or professional adaptation. RESULTS:In most c...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：AIM:To study effectiveness and tolerance of monoclonal antibodies to tumor necrosis factor (the drug remicade) in patients with rheumatoid arthritis (RA). MATERIAL AND METHODS:Remicade treatment results are considered for 25 RA patients receiving methotrexate the activity of which was inadequate for these patients. Re...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：:The authors present the results of examination of 38 patients with various diseases of the pericardium using the CT method. It possesses a high sensitivity and permits one to reveal pericardial effusions as well as tumor lesions of the pericardium. CT has a high resolving power and provides for visualization of of the...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Mitral prolapse (MP) investigations were performed in 76 pilots. MP occurs in pilots rather frequently and in 15% may be responsible for syncope conditions resultant from cardiac arrhythmia, coronaroangiospastic and hypotonic responses to stress. MP diagnosis requires comprehensive examination combining clinical and s...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
