Abstract：
:The authors describe the status of lipid peroxidation (diene conjugates and malonic dialdehyde) and the endogenous antioxidant enzyme superoxide dismutase in the course of the treatment of patients with acute focal pneumonia by means of the use of transthoracic intrapulmonary injections of unithiol and autologous ultraviolet blood radiation (AUVBR). Three groups of patients were entered into the study. The first group included 64 patients who were given transthoracic intrapulmonary injections of unithiol, the second group 58 patients who received 5-7 sessions of AUVBR, in the third group, 52 patients were given transthoracic intrapulmonary injections of unithiol coupled with 3-5 sessions of AUVBR. The control group was made up of 40 patients given intravenous unithiol injections in routine therapeutic doses. The results of the treatment evidence that combined correction of lipid peroxidation carried out in the third group patients was most effective. As regards the times, the positive dynamics of lipid peroxidation and superoxide dismutase activity correlated with the clinical, biochemical and x-ray improvement. Therefore the method of correction in question is a pathogenetically based approach, permitting one to enhance the clinical efficacy of the treatment of patients suffering from acute focal pneumonias and to reduce the times of their stay in the hospital by 5-7 days, on the average.
journal_name
Ter Arkhjournal_title
Terapevticheskii arkhivauthors
Provotorov VM,Zizemskaia EVsubject
Has Abstractpub_date
1992-01-01 00:00:00pages
29-32issue
3eissn
0040-3660issn
2309-5342journal_volume
64pub_type
杂志文章abstract：:Analysis of the results of the diagnostic bronchoalveolar lavage (BAL) in 108 patients has shown that based on the study of the cellular composition of the bronchoalveolar washing (BAW) one can form a judgment about the activity of chronic bronchitis and disseminated processes in the lungs. In individual patients, the...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：AIM:To examine validity of using interferon inductors (amixin and cycloferon) in combined treatment of patients with non-specific ulcerous colitis (NUC). MATERIAL AND METHODS:113 NUC patients received basic antiinflammatory therapy (glucocorticoids and preparations of 5-aminosalycylic acid). Patients of groups 1 and 2...
journal_title：Terapevticheskii arkhiv
pub_type： 临床试验,杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:There was No correlation between the state of immunological reactivity in patients with acute pneumonia and the nature of infiltration of the pulmonary tissue (focal, confluent). Indices characterizing the cellular and humoral immunity links, were, to a large extent, related to a course of disease (complicated, uncomp...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:Based on clinico-endoscopic, x-ray, immunological and immunohistochemical studies the authors demonstrate the role of disorders in the components of humoral and cellular immunity in the development of intestinal inflammation and amyloidosis in patients with periodical disease. Circulatory disorders, congestive hyperem...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：AIM:To investigate verbal dyspnea characteristics in patients with bronchial asthma (BA) and hyperventilation syndrome (HVS). MATERIAL AND METHODS:The trial covered 52 patients with BA, 10 patients with BA combination with HVS and 18 patients with HVS. Verbal dyspnea characteristics were studied with PM. Simon questio...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：:In Russia, diabetes mellitus afflicts 8 million people, 90% of them had type 2 diabetes mellitus (T2DM) and this figure is growing steadily. At the same time there is a rise in the incidence of macrovascular events (unstable angina pectoris, myocardial infarction). Coronary heart disease and its attack are a major cau...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章,评审
doi：
更新日期：2010-01-01 00:00:00
abstract：:The paper is concerned with a case of Brill-Symmers' disease started with the thrombocytopenic syndrome relating to hypersplenism. After splenectomy the first benign stage of disease without eradication therapy lasted over 10 years. Signs of immunological incompetence (signs of secondary infection) and recurring immun...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：AIM:To detect endogenic intoxication syndrome (EIS) and to assess its severity depending on clinical manifestations of rheumatoid arthritis (RA) using laboratory tests. MATERIAL AND METHODS:Laboratory tests including analysis of synovial fluid, blood count with estimation of leucocytic intoxication index, urinalysis, ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：AIM:To compare effectiveness of two long-acting calcium antagonists--amlodipin and diltiazem--in patients with ischemic heart disease (IHD) and stable angina of effort (SAE). MATERIAL AND METHODS:31 IHD patients with SAE entered the double blind randomized trial. The patients received either amlodipin (5-10 mg once a ...
journal_title：Terapevticheskii arkhiv
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2001-01-01 00:00:00
abstract：:The authors provide data obtained during echocardiographic examination of 16 patients with different patterns of alcoholic heart injury primarily at the early stages of alcoholism. The group of patients without heart rhythm abnormality showed a decrease in myocardial contractile function, moderate dilatation of the le...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:A total of 50 patients with essential hypertension, I-II stages, were investigated to study changes in peripheral and intracardiac hemodynamics and myocardial contractility in moderate restriction of sodium chloride in "salt-sensitive" patients (SSP). In such patients (84% of all examinees) with mild arterial hyperten...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：AIM:To evaluate influence of the treatment with systemic glucocorticoid hormones (SGH) during acute exacerbation of moderate and severe chronic obstructive pulmonary disease (COPD) on parameters of respiratory function. MATERIAL AND METHODS:A total of 66 patients with severe COPD were included in the study. Airway res...
journal_title：Terapevticheskii arkhiv
pub_type： 临床试验,杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：AIM:To study types of anxious disorders (AD) in patients with rheumatoid arthritis (RA) and AD correlations with clinicolaboratory indices. MATERIAL AND METHODS:80 RA patients and 38 healthy subjects have undergone MMPI test. RESULTS:95% of the examinees were found to have AD which seem to form in active participatio...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:The authors hold that perfection of local therapeutic service in present-day situation when insurance principles are introduced in medical care may be achieved through design of medico-economic standards of guaranteed minimum of medical aid for each citizen of Russian Federation. This approach allows accurate estimati...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：AIM:To study coronary-myocardial reserve in patients with a programmed pacemaker. MATERIALS AND METHODS:Stress-echocardiography was performed in 64 patients with coronary heart disease (CHD). The stress was induced by a gradual increase in the frequency of electrostimulation (ES) by 10 imp/min from initial 90 imp/min ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:Data are presented on external respiration at rest and during exercise (bicycle ergometry) in 20 patients with chronic circulatory insufficiency due to a variety of heart diseases, as well as variation in the above in the course of treatment with digoxin and calcium antagonist corinfar. External respiration parameters...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：AIM:To study changes in the condition of lymphocyte membranes of patients with acute viral hepatitis B (AVHB) in narcotic addicts. MATERIALS AND METHODS:136 patients with AVHB have been examined for endogenic intoxication (plasma levels of middle-size molecular peptides, urine levels of red cells). 74% of the examinee...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:The use of imatinib mesylate (Glivec) (Novartis Pharma AG, Switzerland) that is the drug of choice in treating patients with chronic myeloid leukemia (CML) has increased 7-year survival and improved the prognosis of the disease. The drug is generally tolerated well; the proportion of patients in whom imatinib treatmen...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：:To develop some individual prognostic criteria of SLE clinical course the Wald's analysis of immunogenetic markers (HLA) was used. The obtained summarized diagnostic coefficients allow predicting a subacute or chronic pattern of the disease, the rate of generalization and the most frequent location of the process in c...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：AIM:To assess the efficacy and safety of long-term treatment with nucleos(t)ide analogues in patients with chronic hepatitis B. MATERIALS AND METHODS:We conducted an observational study in 101 chronic hepatitis B (HBeAg-negative and HBeAg-positive) patients treated (≥3 years) with entecavir, tenofovir or telbivudine. ...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.26442/ 00403660.2019.02.000073
更新日期：2019-03-18 00:00:00
abstract：:Basing on computer processing of 126 primary clinical and laboratory parameters obtained from 92 patients with myelodysplasia and using multifactorial regression analysis, the authors have developed prognostic models of life span and probability of transformation into acute leukemia. The model of life span enabled rec...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:The paper is concerned with a study in which eosinophilic exudative pleuritis was the first sign of drug allergy (penicillin, streptomycin, claphoran), also manifesting itself in fever, hemorrhagic eruption, eosinophilia in the blood. Fast recovery was achieved after discontinuation of antibacterial therapy and prescr...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:A study was made of the impact of a single intake of nifedipine, intal, sodium thiosulfate and essentiale on respiratory function, the blood content of ionized calcium, total calcium, hydroperoxides, total and non-protein thiol groups, and prostaglandins in bronchial asthma patients. All the drugs exerted an antioxida...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:The 5- and 10-year survival rates of all 114 patients with primary DM were 89 and 81%, respectively. Significantly lower survival rates were noted in the patients receiving late and inadequate therapy. Corticosteroid therapy radically changed the outcome of DM, mainly due to early diagnosis and adequate therapy. A sta...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：AIM:To characterize the genotype and genotype-phenotype correlations in patients with Gaucher disease (GD) in the Russian Federation. MATERIALS AND METHODS:One hundred adult patients with GD type 1 were examined. Their clinical study encompassed the evaluation of the severity of osteoarticular lesions from instrumenta...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：:The radioaerosol technique with the use of radioalbumin from the TSK-5 kit and of an ultrasonic inhaler makes it possible to determine primarily the mucociliary clearance of the central parts of the tracheobronchial tree. In patients without any pathology of the respiratory organs, the clearance of the inhaled radioph...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：AIM:To study effectiveness and tolerance of monoclonal antibodies to tumor necrosis factor (the drug remicade) in patients with rheumatoid arthritis (RA). MATERIAL AND METHODS:Remicade treatment results are considered for 25 RA patients receiving methotrexate the activity of which was inadequate for these patients. Re...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：AIM:To study dynamics of ischemic heart disease in exposure of the population of an industrial city to social-economic stress. MATERIAL AND METHODS:Official annual records of Saratov city Health Administration for 1989-1998. In public health evaluation, cardiovascular morbidity is the index rapidly reacting to social-...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
abstract：AIM:To assess orthogonal ECG system McFee-Parungao in exercise test performed by patients with ischemic heart disease (IHD). MATERIAL AND METHODS:The trial included 103 patients: 41 patients with IHD, 23 patients with IHD combined with arterial hypertension and 39 control patients free of IHD. All the patients perform...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：AIM:To determine the effects of menopausal hormone therapy dosage on levels of proinflammatory cytokines and immunoglobulins in bodily fluids of patients with type 2 diabetes mellitus (DM) and chronic obstructive pulmonary disease (COPD) during perimenopause. MATERIALS AND METHODS:The study included 119 perimenopausal...
journal_title：Terapevticheskii arkhiv
pub_type： 杂志文章
doi：10.26442/terarkh2018901079-83
更新日期：2018-11-22 00:00:00
